Laeknabladid最新文献_第6页

[Unlicensed drugs in Iceland in the years 2020 and 2021 with comparison to Sweden in 2020]. [2020年和2021年冰岛无证药品与2020年瑞典的对比]。

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-09-01 DOI: 10.17992/lbl.2023.09.756

Armey Valdemarsdottir, Anna Bryndis Blondal, Hjalti Kristinsson

{"title":"[Unlicensed drugs in Iceland in the years 2020 and 2021 with comparison to Sweden in 2020].","authors":"Armey Valdemarsdottir, Anna Bryndis Blondal, Hjalti Kristinsson","doi":"10.17992/lbl.2023.09.756","DOIUrl":"https://doi.org/10.17992/lbl.2023.09.756","url":null,"abstract":"Introduction: Prescriptions of unlicensed drugs along with public discussion have increased in recent years. The cause of this increase is unclear.Material and methods: This is a retrospective descriptive study of applications of unlicensed drugs in Iceland in the years 2020 and 2021, as well as applications in Sweden for the year 2020. Information was collected on unlicensed prescription applications, registered drugs and stock-out time. Information was analyzed and categorized to describe the scope of unlicensed prescriptions in the two countries during the study time.Results: In Iceland, 49.161 applications were approved in 2020 and 46.581 in 2021. The most common reason for using unlicensed products was that no registered drug was on the market with the same ATC-number (Anatomical Therapeutic Chemical code) and formulation. Shortage of drug was the reason for unlicensed prescription in 8.8% of cases in 2020 and 7.6% in 2021. The list of the 50 most prescribed drugs included the same drugs in 70% of the cases in both years. The five most prescribed drugs were the same in both years. In Sweden, 38.458 applications were approved in 2020. Of the most prescribed unlicensed drug, 46% were as no registered drug with same ATC-number and dosage form was marketed.Conclusion: Many unlicensed drugs, prescribed in Iceland, are the same year after year. Only a small part of the applications approved were due to shortage of drug. The use of drugs without marketing license in Iceland in 2020 was higher than in Sweden when adjusted for the size of the market and population. Getting the five most prescribed unlicensed drugs licensed in Iceland could reduce largely, the total of prescription of unlicensed drugs in Iceland.","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 9","pages":"387-394"},"PeriodicalIF":0.4,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10483855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Quis custodiet medicum?] [谁留着医生？]

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-09-01 DOI: 10.17992/lbl.2023.09.755

Tryggvi Helgason

引用次数: 0

[Physician innovators]. [医生创新者]。

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-09-01 DOI: 10.17992/lbl.2023.09.754

Gunnar Thorarensen

引用次数: 0

[The many faces of Group A Streptococcal infections, case-series of invasive infections in children in Iceland]. [冰岛儿童A群链球菌感染的多面性，侵袭性感染病例系列]。

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-09-01 DOI: 10.17992/lbl.2023.09.758

Elin Ola Klemenzdottir, Arna Yr Karelsdottir, Valtyr Stefansson Thors

引用次数: 0

[To cause no harm. Use and misuse of proton pump inhibitors]. 不造成伤害。质子泵抑制剂的使用和误用]。

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-07-01 DOI: 10.17992/lbl.2023.0708.750

Gudjon Kristjansson

引用次数: 0

[Methylphenidate-induced psychosis in a young adult with newly diagnosed ADHD: A case report]. [甲哌醋酯诱发的新诊断ADHD的年轻成人精神病:一例报告]。

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-07-01 DOI: 10.17992/lbl.2023.0708.753

Ragna Kristin Gudbrandsdottir, Engilbert Sigurdsson, Oddur Ingimarsson

引用次数: 0

[How can Artificial Intelligence be of use in the Healthcare System?] [人工智能如何应用于医疗保健系统?]］

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-07-01 DOI: 10.17992/lbl.2023.0708.749

Steindor Ellertsson

引用次数: 0

[Postpartum hemorrhage in singleton births in Iceland 2013 - 2018, incidence proportion and risk factors]. [冰岛2013 - 2018年单胎产后出血发生率及危险因素分析]。

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-07-01 DOI: 10.17992/lbl.2023.0708.751

Karen Sol Saevarsdottir, Emma M Swift, Kristjana Einarsdottir, Johanna Gunnarsdottir

{"title":"[Postpartum hemorrhage in singleton births in Iceland 2013 - 2018, incidence proportion and risk factors].","authors":"Karen Sol Saevarsdottir, Emma M Swift, Kristjana Einarsdottir, Johanna Gunnarsdottir","doi":"10.17992/lbl.2023.0708.751","DOIUrl":"https://doi.org/10.17992/lbl.2023.0708.751","url":null,"abstract":"Introduction: Many countries have reported an increased incidence proportion of postpartum hemorrhage (PPH). The proportion might also have increased at the National University Hospital of Iceland, based on the registration of the ICD-10 code O72. This study aimed to assess the incidence proportion and risk factors for ≥1000 ml PPH in singleton births in Iceland 2013-2018.Methods: This population-based cohort study included data from the Icelandic Birth register on 21.110 singleton births in 2013-2018. Incidence proportion of PPH was assessed based on three definitions: PPH >500 ml, PPH ≥1000 ml, and O72. Binomial regression was used to assess both the change in the proportion of ≥1000 ml PPH over time, stratified by maternal BMI, and risk factors for ≥1000 ml PPH.Results: There was an inconsistency in the proportion of PPH when defined by blood loss >500 ml and O72. In obese women, PPH ≥1000 ml was more than twice as likely in those delivering in 2018 compared with 2013 (OR 2.23; CI 1.35-3.81). The strongest risk factors were emergency cesarean (OR 2.68; CI 2.22-3.22) and instrumental delivery (OR 2.18; CI 1.80-2.64), but macrosomia, primiparity and BMI ≥30 were also independent risk factors.Conclusion: The incidence proportion of ≥1000 ml PPH has increased among obese women. The detrimental health effects of obesity and the increased prevalence of interventions among these women could explain these results. It is necessary to use registered blood loss in milliliters in the Icelandic Birth Register because of the under-registration of the diagnostic code O72.","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 708","pages":"331-337"},"PeriodicalIF":0.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9689668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Current use of proton pump inhibitors and when to limit, stop or not start treatment]. 【目前质子泵抑制剂的使用及何时限制、停止或不开始治疗】。

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-07-01 DOI: 10.17992/lbl.2023.0708.752

Holmfridur Helgadottir, Einar Stefan Bjornsson

{"title":"[Current use of proton pump inhibitors and when to limit, stop or not start treatment].","authors":"Holmfridur Helgadottir, Einar Stefan Bjornsson","doi":"10.17992/lbl.2023.0708.752","DOIUrl":"https://doi.org/10.17992/lbl.2023.0708.752","url":null,"abstract":"Proton pump inhibitors (PPIs) are potent inhibitors of gastric acid secretion that have changed treatment practice for gastric acid-related disorders. The major adequate indications for their use are treatment of gastro-esophageal reflux disease, peptic ulcers, eradication of Helicobacter pylori infection in combination with antibiotics and prophylaxis for patients on non-steroidal anti-inflammatory or antiplatelet drugs. Since their introduction, clinical success has been accompanied by widespread use of PPIs, which has steadily increased over the last decades without concomitant increase in the incidence of acid-related disorders. PPIs are now among the most widely prescribed class of medications worldwide and around 10% of Icelanders are current PPI users. This increase has been linked to PPI prescription without an indication, or continued use for longer duration than recommended. In recent years, concerns have been raised about PPI overuse and the associated increased risk of harm, not only in terms of increased costs but also the potential risk of physical dependence and long-term side effects of PPIs. The article is based on search in PubMed, the authors' own clinical experience and research, and is intended to provide practice advice on the use of PPIs with focus on appropriate prescription and deprescription of PPIs.","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 708","pages":"338-345"},"PeriodicalIF":0.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9689669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Spontaneous retroperitoneal hemorrhage]. 自发性腹膜后出血。

IF 0.4 4区医学

Laeknabladid Pub Date : 2023-06-01 DOI: 10.17992/lbl.2023.06.748

Jon Bjarnason, Luis Fernando Bazan Asencios, H. Thorisson, K. Reynisson

引用次数: 0