Libyan Journal of Medicine最新文献

{"title":"Endoscopic urgency triaging impacts acute variceal bleeding patient survival and hospital stay length.","authors":"Amr Shaaban Hanafy, Ahmed Behiry, Dalia Mahmoud Abdelmonem Elsherbini, Hasnaa Ali Ebrahim, Ateya Megahed Ibrahim, Khalid I AlQumaizi, Moaz Abulfaraj, Mohamed El-Sherbiny, Hany A Elkattawy","doi":"10.1080/19932820.2025.2516313","DOIUrl":"10.1080/19932820.2025.2516313","url":null,"abstract":"<p><p>Upper gastrointestinal bleeding (UGIB) needs accurate endoscopic timing. This study investigates the debate on the necessity of upper endoscopy in UGIB, proposes predictors for adverse outcomes if urgent endoscopy is deferred, and assesses the risk to patient health or results compared to non-urgent endoscopy. A non-randomized controlled study conducted at a single center involved 200 patients with acute life-threatening UGIB. The study group comprised 100 who had an urgent endoscopy within 6 h and a control group included 100 who waited or declined the procedure within 6-24 h. Glasgow-Blatchford score was used for risk stratification of UGIB. Doppler ultrasound was applied to measure lower esophageal wall thickness. D-dimer, lactate, and procalcitonin were measured. The study group revealed recurrent bleeding after 13.5 ± 3.6 days. Death occurred in 4 (4%) which is statistically significant lower (<i>p</i> = 0.024) compared to the control group due to hypovolemic shock, pulmonary embolization, or aspiration pneumonia. Control group showed recurrent bleeding following 15.8 ± 4.7 days (<i>p</i> = 0.306). Death occurred in 14 (14%) of patients due to hypovolemic shock, disseminated intravascular coagulation, or pulmonary embolization. A shorter hospital stay (8.4 ± 3.2 days) was evident in the study group compared to the control group (16.4 ± 2.76 days, <i>p</i> < 0.001). D-dimer, serum lactate, and procalcitonin (Adjusted Odds Ratio (AOR) = 1.004, 2.207, 0.563, <i>p</i> < 0.001, <0.001, 0.011, respectively), and their corresponding values at follow-up (AOR = 0.988, 0.528, 177.04, <i>p</i> < 0.001, 0.011, <0.001, respectively) were significantly associated with higher mortality. Waiting time till endoscopy, baseline D-dimer (AOR = 1.794, 0.998, <i>p</i> < 0.001, 0.014, respectively), creatinine, procalcitonin, and esophageal wall thickness at follow-up were significantly associated with longer hospital stay. The study suggests that higher lower esophageal wall thickness and elevated serum lactate, D-dimer, and procalcitonin are novel triaging markers for early endoscopic intervention, which can improve patient outcomes, reduce blood transfusion risks, and eliminate unnecessary procedures.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"20 1","pages":"2516313"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12160328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Androgen receptor expression in triple negative breast cancer: an Algerian population study.","authors":"Amel Hedjem, Amal Kouchkar, Amel Ladjeroud, Nacera Zerrouki, Fatima Benaissa, Nasir A Ibrahim, Mohammed Saad Aleissa, Nosiba S Basher, Assia Derguini, Takfarinas Idres, Karim Houali","doi":"10.1080/19932820.2025.2535778","DOIUrl":"10.1080/19932820.2025.2535778","url":null,"abstract":"<p><p>Triple-negative breast cancer (TNBC) is a molecular subtype of breast cancer characterized by the absence of estrogen and progesterone receptors and the lack of HER2 overexpression. TNBC is highly heterogeneous, complicating the identification of new therapeutic targets. However, the expression of the androgen receptor (AR) in the luminal androgen receptor (LAR TNBC) subgroup has opened the door to alternative therapeutic approaches. This study aimed to assess AR expression and correlate it with clinicopathological factors in 160 early-stage TNBC patients treated from February 2015 to February 2017. Our findings reveal that AR expression is observed in 16.87% (27/160) of ≥1% AR positivity cases. Moreover, a significant 12.5% (20/160) was found in ≥10% AR positive cases. Positive AR expression was inversely correlated with a high Ki-67 proliferation index and with the basal immunophenotype. The five-year survival rate for our cohort was 83.12%, and no significant association between AR expression and overall survival was observed (<i>p</i> = 0.77). The study highlights the potential role of AR expression in TNBC and its implications for therapeutic strategies, although no significant association with overall survival was found.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"20 1","pages":"2535778"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation and validation for the Arabic version of asthma numeracy questionnaire (Ar-ANQ) in adults: a factor and Rasch analyses study.","authors":"Walid Al-Qerem, Anan Jarab, Khaled Al Oweidat, Judith Eberhardt, Majd Kasasbeh, Lujain Al-Sa'di","doi":"10.1080/19932820.2025.2538333","DOIUrl":"10.1080/19932820.2025.2538333","url":null,"abstract":"<p><p>Asthma is a prevalent chronic respiratory disease associated with significant morbidity and mortality globally. Effective self-management of asthma depends on adequate numeracy skills, which are essential components of health literacy (HL). Although the Asthma Numeracy Questionnaire (ANQ) has been validated among parents of asthmatic children, no previous studies have specifically validated the tool among adult patients with asthma. Therefore, this study aimed to validate the Arabic version of the Ar-ANQ among adult patients with asthma in Jordan, assess their asthma-related numeracy skills, and identify demographic and clinical factors associated with numeracy. A cross-sectional study was conducted with 398 adult patients with asthma attending the Respiratory Therapy Unit at the University of Jordan Hospital (JHU) from November 2024 to April 2025. Participants completed the Arabic Ar-ANQ and provided demographic information. The questionnaire's validity and reliability were evaluated using Confirmatory Factor Analysis (CFA) and Rasch analysis. Associations between Ar-ANQ scores and sociodemographic variables were analyzed using quantile regression. Confirmatory Factor Analysis (CFA) confirmed the unidimensional structure of the Ar-ANQ (SRMR = 0.02, CFI = 0.98, GFI = 0.99, TLI = 0.95), demonstrating high internal consistency (Cronbach's α = 0.80). Rasch analysis further supported the instrument's reliability, with acceptable infit and outfit statistics, as well as item and person separation reliability indices. Numeracy skills varied significantly among participants, influenced by education level and income, with higher Ar-ANQ scores observed among those with higher educational attainment and income levels. The Ar-ANQ is a valid and reliable instrument for evaluating numeracy skills essential for effective asthma self-management among adult asthmatic patients. Its use can facilitate targeted educational interventions and improved asthma control.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"20 1","pages":"2538333"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness of prevention program for type 2 diabetes mellitus in high risk patients in the Republic of Srpska, Bosnia and Herzegovina.","authors":"Dragana Grujić-Vujmilović, Kristina Veljković, Živana Gavrić, Snježana Popović-Pejičić","doi":"10.1080/19932820.2024.2437226","DOIUrl":"10.1080/19932820.2024.2437226","url":null,"abstract":"<p><p>The Republic of Srpska (RS), as a part of the Western Balkans (WB) region, has a higher diabetes prevalence than the EU. This study aims to assess the cost-effectiveness of early treatment of high-risk patients with pre-diabetes and undiagnosed diabetes in our setting. We designed a Markov chain Monte Carlo (MCMC) model which reflects the current International Diabetes Federation (IDF) three-step plan for the prevention of T2DM in those at increased risk. The model captures the evolution of the disease in FINDRISC high-risk patients from normal glucose tolerance (NGT) to impaired fasting glucose (IFG) or impaired glucose tolerance (IGT) and then to T2DM and its complications. We developed two MCMC models, in order to follow the progression of the disease in high-risk cases, ie, when early treatment is undertaken or when it is not undertaken. The health costs and quality adjusted life years (QALY) were discounted at an annual rate of 3%. The key model parameters were varied in one-way and probabilistic sensitivity analysis. Early treatment resulted in increased life expectancy, postponement of the onset of diabetes and increased QALY for all patients. The discounted incremental cost-effectiveness-ratios (ICER) in NGT, IFG, IGT, and T2DM patients were -289.9, 9724.03, -1478.59 and 4084.67 €. In high-risk IGT patients, ICER was the most favorable, being both a cost saving and QALY gaining, with the consistent results confirmed by the sensitivity analysis. The results recommend the acceptance of a new health policy of identifying IGT patients with the use of FINDRISC questionnaire and plasma glucose measurements; providing them with a lifestyle change program; and implementing intensive diabetes treatment, as their disease progresses. Our results are especially significant for the Western Balkan countries, since this was the first cost-effectiveness study of T2DM prevention in this region.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"20 1","pages":"2437226"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction.","authors":"","doi":"10.1080/19932820.2025.2475687","DOIUrl":"10.1080/19932820.2025.2475687","url":null,"abstract":"","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"20 1","pages":"2475687"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitudes, and practices toward Mpox and vaccination: a cross-sectional study in Saudi Arabia.","authors":"Amal K Suleiman","doi":"10.1080/19932820.2025.2528299","DOIUrl":"10.1080/19932820.2025.2528299","url":null,"abstract":"<p><p>Mpox is re-emerging globally and poses a growing public health threat, particularly in nonendemic countries such as Saudi Arabia. Given the limited national research on this topic, this study aimed to assess public perceptions, knowledge, and willingness to receive Mpox vaccination among the Saudi population. A cross-sectional online survey was conducted between March and August 2024 using a self-administered questionnaire adapted from previous studies. Participants aged 18 years and older residing in Saudi Arabia were included. Incomplete responses were excluded. Data were analyzed using Epi Info 7.2, employing descriptive statistics and Fisher's exact test to evaluate associations (<i>p</i> < 0.05 considered significant). A total of 2847 complete responses were received (response rate: 94.9%). Among respondents, 71.0% reported being aware of Mpox, while 47.1% had received information on how the virus spreads. Non-Saudi residents represented 61.1% of the sample. The most frequently cited information sources were social media and websites (54.2%), followed by word-of-mouth (22.3%), traditional media (18.5%), and healthcare workers (5.0%). A substantial proportion (93.2%) reported a lack of awareness regarding preventive measures, and 67.3% expressed hesitancy toward Mpox vaccination. These findings reveal significant gaps in knowledge and preparedness concerning Mpox among the population in Saudi Arabia. Strengthening public education and enhancing communication through reliable health sources are essential to improve awareness and support future vaccination efforts.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"20 1","pages":"2528299"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12217092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A survey into the utilization of probiotics and medicinal plants among individuals afflicted with gastrointestinal disorders in healthcare institutions in Saïda, Algeria.","authors":"Lamia Abir Tazi, Yasmina Benabdesslem, Sabrina Amara, Kadda Hachem","doi":"10.1080/19932820.2024.2317492","DOIUrl":"10.1080/19932820.2024.2317492","url":null,"abstract":"<p><p><b>Aim:</b> Functional gastrointestinal (GI) disorders are recognized as a major public health concern worldwide. These disorders involve persistent digestive symptoms indicative of digestive tract dysfunction.<b>Materials and Methods:</b> A survey examining the utilisation of probiotics and medicinal plants as supplementary treatments was conducted on 160 patients with GI disorders at healthcare institutions in Saïda from March to April 2023 using questionnaires that had been previously adapted and tested for reliability with Cronbach's alpha test. Raw data collected through the questionnaires were transferred to a database and analysed using SPSS software.<b>Results:</b> Overall, 49.38% of participants possessed knowledge of or actively utilised probiotics; such awareness was strongly associated with the participants' educational attainment (<i>p</i> = 0.029). The noteworthy probiotic supplements were Biocharbon (36.09%), Lactocil (15.38%), Smebiocta (13.61%), Ultrabiotic Adult (12.43%), Effidigest (12.43%), and Ultralevure (7.69%). During crisis, individuals tended to consume natural goods rich in probiotics, including yoghurt (13.26%) and fermented milk (8.60%), as well as foods rich in prebiotic fibre, including vegetables (18.99%), fruits (13.26%), wheat (9.67%), bran (7.52%), rye (6.81%), and oat flakes (6.45%). Additionally, 77.56% of patients used medicinal plants during crises, with <i>Mentha spicata</i> (12.2%), <i>Thymus vulgaris</i> (11.3%), <i>Pimpinella anisum</i> (8.5%), <i>Cuminum cyminum</i> (8.0%), <i>Punica granatum</i> (7.8%), <i>Trachyspermum ammi</i> (7.5%), and <i>Senna acutifolia</i> (7.0%) being the more commonly favoured options in phytotherapy. The main focus of these herbs was to alleviate bloating (57%), constipation (30.12%), and diarrhoea (12.87%) (<i>p</i> < 0.001). The most frequently utilised plant parts were leaves (47.30%), seeds (25.21%), and bark (13.21%). Most patients (82.91%) favoured infusion as their preferred consumption method, and approximately 85.43% believed in phytotherapy's ability to extend symptomatic relief.<b>Conclusion:</b> The understanding of probiotics is still in its infancy, whereas phytotherapy is more widely accepted by patients. Nonetheless, patients are open to the exploration of natural alternatives to conventional medicines.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2317492"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10878339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139900765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do-not-attempt resuscitation policy reduced in-hospital cardiac arrest rate and the cost of care in a developing country.","authors":"David O Alao, Snaha M Abraham, Nada Mohammed, George D Oduro, Mohammed A Farid, Roxanne M Roby, Chris Oppong, Arif A Cevik","doi":"10.1080/19932820.2024.2321671","DOIUrl":"10.1080/19932820.2024.2321671","url":null,"abstract":"<p><p>We aim to study the characteristics and outcomes of patients with a Do-Not-Attempt Resuscitation and to determine its impact on the Cost of In-Hospital Cardiac Arrest. A retrospective study of all adult patients admitted to the hospital from June 2021 to May 2022 who had a Do-Not-Resuscitate order. We abstracted patients' socio-demographics, physiologic parameters, primary diagnosis, and comorbidities from the electronic medical records. We calculated the potential economic cost using the median ICU length of stay for the admitted IHCA patients during the study period. There were 28,866 acute admissions over the study period, and 788 patients had DNR orders. The median (IQR) age was 71 (55-82) years, and 50.3% were males. The most prevalent primary diagnosis was sepsis, 426 (54.3%), and cancer was the most common comorbidity. More than one comorbidities were present in 642 (80%) of the cohort. Of the DNR patients, 492 (62.4%) died, while 296 (37.6%) survived to discharge. Cancer was the primary diagnosis in 65 (22.2%) of those who survived, compared with 154 (31.3%) of those who died (P = 0.002). Over the study period, 153 patients had IHCA and underwent CPR, with an IHCA rate of 5.3 per 1,000 hospital admissions. Without a DNR policy, an additional 492 patients with cardiac arrest would have had CPR, resulting in an IHCA rate of 22.3 per 1000 hospital admissions. Most DNR patients in our setting had sepsis complicated by multiple comorbidities. The DNR policy reduced our IHCA incidence by 76% and prevented unnecessary post-resuscitation ICU care.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2321671"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10898264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139974243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of multi-drug resistant bacteria in intensive care units at Tripoli University Hospital, Tripoli, Libya.","authors":"Khaled Ibrahim, Dalal Thwood, Hajer ELgheriani, Mohamed Salem, Zaynab Elgadiym, Ahmed Zaghdani, Inas Alhudiri, Abdulraouf Habibi, Abdurrezagh Elfahem, Saadeddin Belaid, Otman Ermithi, Mahmoud Almaghrabi, Abubaker ELmaryul, Suad Almadah, Abdunnabi Rayes, Salah Edin El Meshri, Allaaeddin El Salabi, Adam Elzagheid","doi":"10.1080/19932820.2024.2348235","DOIUrl":"10.1080/19932820.2024.2348235","url":null,"abstract":"<p><p>Among hospitalized patients worldwide, infections caused by multidrug-resistant (MDR) bacteria are a major cause of morbidity and mortality. This study aimed to isolate MDR bacteria from five intensive care units (ICUs) at Tripoli University Hospital (TUH). A prospective cross-sectional study was conducted over a seven-month period (September 2022 to March 2023) across five ICUs at TUH. A total of 197 swabs were collected from Patients', healthcare workers' and ICUs equipment. Samples collected from patients were nasal swabs, oral cavity swabs, hand swabs, sputum specimens, skin swabs, umbilical venous catheter swabs, and around cannula. Swabs collected from health care workers were nasal swabs, whereas ICUs equipment's samples were from endotracheal tubes, oxygen masks, and neonatal incubators. Identification and antimicrobial susceptibility test was confirmed by using MicroScan auto SCAN 4 (Beckman Coulter). The most frequent strains were Gram negative bacilli 113 (57.4%) with the predominance of <i>Acinetobacter baumannii</i> 50/113 (44%) followed by <i>Klebsiella pneumoniae</i> 44/113 (40%) and <i>Pseudomonas aeruginosa</i> 6/113 (5.3%). The total Gram positive bacterial strains isolated were 84 (42.6%), coagulase negative <i>Staphylococci</i> 55 (66%) with MDRs (89%) were the most common isolates followed by <i>Staphylococcus aureus</i> 15 (17.8%). Different antibiotics were used against these isolates; Gram- negative isolates showed high resistance rates to ceftazidime, gentamicin, amikacin and ertapenem. <i>A. baumannii</i> were the most frequent MDROs (94%), and the highest resistance rates in Gram-positive strains were observed toward ampicillin, oxacillin, ampicillin/sulbactam and Cefoxitin, representing 90% of total MDR Gram-positive isolates. ESBL and MRS were identified in most of strains. The prevalence of antibiotic resistance was high for both Gram negative and Gram positive isolates. This prevalence requires strict infection prevention and control intervention, continuous monitoring, implementation of effective antibiotic stewardship, immediate, concerted and collaborative action to monitor its prevalence and spread in the hospital.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2348235"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11080667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Ramadan on cognitive functions in young boys.","authors":"Amira Miladi, Mohamed Ali Saafi, Imed Latiri","doi":"10.1080/19932820.2024.2301830","DOIUrl":"10.1080/19932820.2024.2301830","url":null,"abstract":"<p><p>Fasting during Ramadan involves abstaining from food and drink from dawn to sunset, potentially influencing cognitive functions essential for the intellectual development of the youth. Therefore, understanding the effects of fasting on these functions in children/adolescents provides valuable perspectives to enhance education and promote mental well-being. However, studies on children/adolescents in this context are still limited. To evaluate the impact of Ramadan fasting on cognitive functions, including information processing speed, inhibition, decision-making, and auditory attention processes among children and adolescents aged 11 to 15 years. This study was conducted with 24 healthy children/adolescents (aged 12.84 ± 0.69 years). The experimental protocol consisted of two sessions: Before-Ramadan (BR) and at the beginning of the second week of Ramadan (R2). At each session, the boys were randomly tested on simple reaction time (SRT), choice reaction time (CRT), negative priming reaction time (NPRT), and auditory discrimination (P300). The tests were administered and scored by the same person in the different sessions. The study found that Ramadan fasting did not have an effect on various reaction times or on electro-physiological data, including P300 amplitude and latency. The current study, conducted with healthy children/adolescents, indicates that Ramadan fasting had no impact on various reaction times (SRT, CRT, NPRT), suggesting the preservation of information processing speed and decision-making, even in the face of increased task complexity. This is evident, on the one hand, through the maintenance of the ability to react to unexpected events, and, on the other hand, through the mastery of resistance to automatism, thus reflecting the preservation of inhibitory function (NPRT). Regarding P300 data, the absence of changes in latencies and amplitudes suggests that Ramadan fasting did not alter either the evaluation time of auditory stimuli or auditory attention processes.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2301830"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10786423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}