Libyan Journal of Medicine最新文献

{"title":"Mapping the scholarly landscape of Saudi Arabia-related folk medicine: a bibliometric study.","authors":"Mohammed M Ghoneim, Eslam Kamal Fahmy, Manal Nael, Mohamed El-Sherbiny, Rasha Hamed Al-Serwi, Saddam Hossain, Khaled Elokely, Naved Ahmad","doi":"10.1080/19932820.2026.2681841","DOIUrl":"10.1080/19932820.2026.2681841","url":null,"abstract":"<p><p>Folk medicine remains an important component of health practices in Saudi Arabia and continues to attract growing scholarly attention. This study maps the scholarly landscape of folk medicine research related to Saudi Arabia by examining publication trends, author keywords, collaboration among institutions and countries, and the impact of authors and sources. Publications were retrieved from the Scopus and Web of Science databases using Saudi Arabia as the country affiliation. After PRISMA-guided identification, screening, deduplication, and eligibility assessment, 2527 publications published between 1989 and 2024 were retained for analysis. Bibliometrix was used for bibliometric computation and visualization, and VOSviewer was used to map country co-authorship and keyword co-occurrence networks. The results show sustained growth in publication output, strong participation by Saudi institutions, and broad international collaboration. The most prominent research themes were antioxidant activity, antimicrobial properties, herbal medicine, and traditional medicine. These findings provide a bibliometric overview of knowledge production in this area and may inform future systematic, clinical, and policy-oriented research on traditional medicine in Saudi Arabia.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2681841"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13235254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148158855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Decayed, Missing, Filled Teeth (DMFT) index and diabetes mellitus among adults in Central Sudan: a community-based cross-sectional study.","authors":"Amal O Bashir, Muhamood Moothedath, Adil Abalkhail, Faraj Alotaiby, Saeed M Omar, Ishag Adam","doi":"10.1080/19932820.2026.2732308","DOIUrl":"10.1080/19932820.2026.2732308","url":null,"abstract":"<p><p>The association between diabetes mellitus (DM) and the Decayed, Missing, Filled Teeth (DMFT) index is not yet settled. This study aimed to assess associations between DM and the DMFT index among adults in Central Sudan. A community-based cross-sectional study was conducted among adults (aged ≥ 18 years) in Central Sudan using a multistage stratified random sampling design. Dental morbidity was assessed using the DMFT index as a continuous dependent variable. Modified multivariate Poisson regression was used to calculate Adjusted Relative Risks (ARR) for associated factors. Seven hundred and seventy-three adults were enrolled. The median (interquartile range, IQR) DMFT index was 5 (2-10), and 14.6% of participants had DM. After adjustment, older age, lower education, and unemployment were significantly associated with the DMFT index. DM was associated with the DMFT index (ARR = 1.18, 95% CI = 1.10-1.26). Glycated (HbA1c) levels were also independently associated with increased DMFT index (ARR = 1.03, 95% CI = 1.02-1.04). DM is associated with DMFT index among adults in Central Sudan. There is a need to integrate oral and systemic health initiatives in Sudan.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2732308"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149018708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fractured instruments in endodontics: understanding incidence, mechanisms, and emerging retrieval techniques.","authors":"Ali Robaian AlQahtani","doi":"10.1080/19932820.2026.2690693","DOIUrl":"https://doi.org/10.1080/19932820.2026.2690693","url":null,"abstract":"<p><p>Fractured instrument retrieval remains one of the most challenging aspects of endodontics, with reported incidence rates ranging from 0.3% to 12%. This complication is particularly common with nickel‒titanium (NiTi) rotary files used in curved canals. Instrument separation hinders effective canal disinfection, compromises the quality of obturation, and may necessitate additional interventions such as bypassing, retrieval, or surgical management. Conventional retrieval techniques often lead to dentin loss, compromising root structure. The use of dental operating microscopes and their integration with ultrasonic troughs, microtubes, and specialized retrieval kits, including loop devices, has significantly enhanced the predictability of retrieval procedures while minimizing the loss of tooth structure. However, the effectiveness of these methods remains highly dependent on operator skill. Numerous innovations are continually emerging to facilitate retrieval, with recent attention on magnetic fields. Studies on such emerging devices utilizing magnetic and electromagnetic attraction have introduced a promising new direction for further exploration. This review aims to provide a comprehensive, evidence-based perspective to guide clinical decision-making and keep practitioners updated about the latest advancements in minimally invasive retrieval techniques in endodontic practice.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2690693"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health literacy, medication adherence, and quality-of-life scores in Jordanian adults with chronic diseases: a dual analytical study using the long-term conditions questionnaire and the EuroQol five-dimension three-level questionnaire.","authors":"Walid Al-Qerem, Anan Jarab, Judith Eberhardt, Salwa Abdo, Lujain Al-Saa'di, Razan Al-Shehadeh, Dana Khasim, Ruba Zumot, Sarah Khalil","doi":"10.1080/19932820.2026.2690691","DOIUrl":"10.1080/19932820.2026.2690691","url":null,"abstract":"<p><strong>Aims: </strong>This study examined the association of health literacy with quality-of-life outcomes among Jordanian adults with chronic diseases using two patient-reported outcome measures, the Long-Term Conditions Questionnaire (LTCQ) and the EuroQol five-dimension, three-level questionnaire (EQ-5D-3L). It also compared conventional regression and machine-learning (ML) approaches for modelling these relationships.</p><p><strong>Materials and methods: </strong>In this cross-sectional online study, Arabic-language questionnaires were completed by Jordanian adults aged 18 years or older with at least one chronic physical, mental, or neurological condition. The survey, designed to take 10-12 minutes, included the LTCQ, EQ-5D-3L, Medication Adherence Report Scale (MARS-5), and 12-item Health Literacy Scale (HLS-Q12). A total of 901 complete responses were analyzed. Data were split into training (<i>n</i> = 633) and test (<i>n</i> = 268) sets. Multiple linear regression was used for LTCQ, Tobit regression for EQ-5D-3L index scores, and ML models were trained to explore nonlinear associations.</p><p><strong>Results: </strong>Health literacy and medication adherence were positively associated with both LTCQ (beta = 3.923 and 2.219, respectively; both <i>p</i> < 0.001) and EQ-5D-3L index scores (beta = 0.025, <i>p</i> = 0.001; beta = 0.020, <i>p</i> = 0.009). Number of medications was inversely associated with both outcomes. In 10-fold cross-validation, Extreme Gradient Boosting (XGBoost) showed the lowest average root mean square error (RMSE) for LTCQ (9.18; coefficient of determination [R²] = 0.384) and EQ-5D-3L (0.172; R² = 0.193), although differences between the leading models were modest.</p><p><strong>Conclusion: </strong>LTCQ and EQ-5D-3L showed overlapping but distinct association patterns. LTCQ was more strongly linked with psychosocial and self-management variables, whereas EQ-5D-3L was more closely aligned with medication burden and clinical comorbidity. These findings should be interpreted as associative rather than causal and as differences in captured dimensions rather than evidence of instrument superiority.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2690691"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13288714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148273530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to ethics reporting standards in locally accredited medical journals: a case study from a developing country.","authors":"Amin Bredan","doi":"10.1080/19932820.2026.2698880","DOIUrl":"10.1080/19932820.2026.2698880","url":null,"abstract":"<p><p>To contribute to local government efforts to regulate scholarly journals in Libya, this study was undertaken to evaluate the reporting of ethics approval and participant consent in Libyan medical journals accredited for faculty promotion. A total of 752 articles involving human research, published between 2021 and 2025 in eleven accredited Libyan medical journals, were examined for the presence of documented ethics approval and participant consent. Four of eleven journals had clear policies requiring reporting of both criteria. Overall, 18.1% of articles reported ethics approval together with consent, 12.4% reported only approval, 20.5% reported only consent, and 49.1% reported neither. Chi-square analysis showed a significant difference in reporting patterns across the journal quartiles (χ²(9) = 31.9, <i>p</i> < 0.001). Journals in lower locally-assigned quartiles were significantly less likely to report ethics approval, while consent reporting did not differ by quartile. Prospective studies had the highest full compliance rate (23.8%) and case reports the lowest (2.5%), and in the most compliant journal, 65.4% of prospective studies were fully compliant. In one journal, no articles were fully compliant. In conclusion, a large fraction of articles in Libyan accredited journals lacks documentation of ethics approval and participant consent, in contradiction to the journals' stated policies. The Ministry of Higher Education and Scientific Research is called on to enforce reporting standards in the journals it has accredited for faculty promotion.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2698880"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13520857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148814785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating immunophenotyping and morphology in the diagnosis of acute leukemia at the National Oncology Center, Sana'a, Yemen.","authors":"Salah Mansour Ali Al-Aghbri, Hafiz A Al-Nood, Naif Mohammed Al-Haidary, Fuad Ahmed Balkam","doi":"10.1080/19932820.2026.2735579","DOIUrl":"10.1080/19932820.2026.2735579","url":null,"abstract":"<p><p>Accurate diagnosis of acute leukemia (AL) is essential for management. Morphological assessment is used in resource-limited settings, but interpretation can be challenging in ambiguous cases. Flow cytometric immunophenotyping provides diagnostic precision, yet its utility in Yemen remains underreported. This study aimed to assess the concordance between morphological diagnosis and flow cytometric immunophenotyping in newly diagnosed patients at the National Oncology Center, Sana'a, Yemen, and describe discordant cases and antigen-expression patterns. An exploratory prospective cross-sectional diagnostic-agreement study was conducted in July-August 2024. Seventy-five newly diagnosed patients were evaluated using morphology and immunophenotyping. Concordance, antigen expression patterns, discordant cases, and hematological parameters were assessed. By immunophenotyping, 42 patients (56.0%) had precursor acute lymphoblastic leukemia (ALL), 32 (42.7%) had acute myeloid leukemia (AML), and 1 (1.3%) had Burkitt lymphoma/leukemia. For comparative analyses, the Burkitt case was included in the ALL analytical group. The participants included 40 males (53.3%) and 35 females (46.7%), with ages ranging from 8 months to 75 years (mean 24.5 ± 21.2 years). In the analytical groups, children accounted for 69.8% of ALL-group cases, whereas 81.3% of AML cases were adults. The concordance between morphology and immunophenotyping was 89.3%, with <i>κ </i>= 0.79 (95% CI: 0.65-0.93, <i>p </i>< 0.001). Eight cases (10.7%) were discordant, including reclassification of ALL to AML and vice versa. Aberrant antigen expression contributed to misclassification, with examples of CD19 positivity in AML and CD2/CD7 co-expression in AML profiles. Hematological parameters did not differ significantly between AML and ALL, including platelet count (<i>p </i>= 0.084). Morphology demonstrates high agreement with immunophenotyping in the diagnosis of acute leukemia. Flow cytometry supports more precise lineage assignment, particularly in ambiguous cases and those with aberrant markers. Expanding the diagnostic infrastructure and improving access to immunophenotyping may strengthen leukemia diagnosis and care in Yemen, particularly when used as part of an integrated diagnostic approach.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2735579"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13591964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary cross-cultural adaptation and validation of the organizational commitment questionnaire (OCQ-18) in a Tunisian nursing context.","authors":"Sawsen Jomâa, Sabine Pohl, Asma Kasdallah, Asma Zorgati","doi":"10.1080/19932820.2026.2743457","DOIUrl":"10.1080/19932820.2026.2743457","url":null,"abstract":"<p><p>A few validated instruments exist in Arabic to assess Organizational commitment, which limits research and practical applications in Arabic-speaking contexts. This study aimed to translate, culturally adapt and validate the Organizational Commitment Questionnaire developed by Allen, Meyer and Smith (1993) for use in Arabic-speaking nurses. A cross-sectional study was conducted among nurses at Sahloul University Hospital in Sousse, Tunisia using a convenience sampling method. The main inclusion criterion was primarily having more than 6 months of work experience. The Organizational Commitment Questionnaire was translated following the guidelines of Vallerand (1989). Content validity was ensured by expert review, construct validity was examined through exploratory factor analysis, and reliability was assessed using Cronbach's alpha coefficients and intraclass correlation coefficients to evaluate internal consistency and stability. A total of 180 participants completed the Arabic OCQ. The Arabic scale showed a strong Pearson correlation with the original English version (r = 0.696, <i>p</i> < 0.01). EFA supported the three-factor structure (affective, continuance, and normative commitment) consistent with Allen and Meyer's model. The Kaiser-Meyer-Olkin index was 0.806, and Bartlett's test was significant (<i>p</i> < 0.001). Internal consistency was acceptable across subscales (Cronbach's <i>α</i> = 0.63, 0.67, and 0.74), and the intraclass correlation coefficients indicated excellent reliability of a single administration (ICC mean = 0.941). The Arabic version showed adequate psychometric properties, supporting its validity and reliability for assessing organizational commitment among Arabic-speaking nurses and enabling cross-cultural research in occupational and health psychology.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2743457"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13660546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selenium/Zinc nanocomposite (Se/Zn NC) bioengineered by <i>Bacillus rugosus</i> metabolites: physicochemical characterization, anti-inflammatory, and antidiabetic activities.","authors":"Ibrahim M Ibrahim, Hanadi A Alahmadi, Anes A Al-Sharqi, Vin Aldoski, Dareen Alyousfi, Rawabi A Alashari, Sozan M Abdelkhalig, Mohammed K Alghamdi, Mona Othman I Albureikan, Faisal Miqad K Albaqami, Zinab Alatawi, Nidal Mohammed Zabermawi, Ahmed Ghareeb","doi":"10.1080/19932820.2026.2746284","DOIUrl":"10.1080/19932820.2026.2746284","url":null,"abstract":"<p><p>This study reports the biosynthesis of a Selenium/Zinc nanocomposite (Se/Zn NC) using a marine bacterial extract from <i>Bacillus rugosus</i> SYG20. FT-IR detected Zn-O stretching vibrations at 614.81, 500.71, and 463.61 cm⁻¹, together with shifts in biomolecule peaks. XRD revealed a hexagonal wurtzite structure with an average crystallite size of 14.9 nm, and UV-Vis spectroscopy gave an optical band gap of 3.46 eV. TEM showed spherical particles of 10-80 nm, while HRTEM lattice fringes and a polycrystalline diffraction pattern matching cubic ZnSe planes confirmed strong interfacial Se-Zn coordination. DLS indicated a hydrodynamic diameter of 87 nm with a polydispersity index of 0.28. EDX confirmed Se incorporation at 7.0 wt% (Zn:Se atomic ratio ≈ 1.6:1). XPS showed Zn in the divalent state and Se bound to the metal centers rather than as elemental selenium, with a Zn 2p binding-energy shift indicating interfacial coordination rather than a native oxide layer. Hemolysis remained below 1.5% even at 1000 μg/mL, and cytotoxicity against WI-38 normal fibroblasts showed a wide safety margin (IC₅₀ = 392.64 ± 4 μg/mL). The nanocomposite exhibited strong antioxidant activity, with IC₅₀ values of 11.85 ± 0.11 μg/mL (DPPH) and 11.46 ± 0.05 μg/mL (ABTS⁺^•), reaching 94.4% and 93.9% inhibition, respectively. Anti-inflammatory assays gave IC₅₀ values of 6.67 ± 0.5 μg/mL for COX-1 and 14.12 ± 0.1 μg/mL for COX-2. Protein denaturation was inhibited with an IC₅₀ of 2.04 ± 0.05 μg/mL, nearly matching diclofenac sodium (2.01 ± 0.04 μg/mL). Antidiabetic screening showed α-amylase and α-glucosidase inhibition with IC₅₀ values of 5.24 and 7.84 μg/mL, and 95.4% and 95.7% blockade at 1000 μg/mL. These in vitro findings support the potential of <i>B. rugosus</i>-derived Se/Zn NC against oxidative stress-related metabolic disorders.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2746284"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13665700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rotation-traction manipulation versus cervical traction for axial neck pain caused by cervical degenerative disc disease: a multicenter randomized controlled trial.","authors":"Yuhang Yang, Ping Wang, Minshan Feng, Xunlu Yin, Aifeng Liu, Chengliang Zhong, Shengqiang Zhang, Futai Gong, Jian Liu, Zhiquan Wang, Bifeng Fu","doi":"10.1080/19932820.2026.2697380","DOIUrl":"10.1080/19932820.2026.2697380","url":null,"abstract":"<p><strong>Background: </strong>Axial neck pain is a common manifestation of cervical degenerative disc disease (CDD). Rotation-traction manipulation (RTM) is widely used in China, but its comparative effectiveness and safety versus cervical traction remain uncertain.</p><p><strong>Methods: </strong>In this prospective multicenter randomized controlled trial, 154 adults with CDD-related axial neck pain were randomized 1:1 to receive RTM (7 sessions over 2 weeks) or cervical traction (daily for 2 weeks). Outcomes were assessed at baseline, during treatment, and at 1 and 3 months after treatment. The primary outcome was pain intensity measured by the visual analogue scale (VAS); secondary outcomes were neck tenderness score (NTS) and cervical range of motion (ROM). Intention-to-treat analyses with multiple imputation were performed.</p><p><strong>Results: </strong>All 154 randomized participants were included in the analyses, and 151 completed follow-up. Both groups showed significant improvement over time in VAS and ROM (both P < 0.001). Confirmatory mixed-effects analyses did not demonstrate significant between-group differences in VAS or ROM after adjustment for multiple comparisons. Exploratory analyses suggested that RTM provided faster improvement during the treatment phase and a small cumulative advantage in pain reduction, whereas cumulative ROM improvement did not differ significantly between groups. RTM was also associated with a faster reduction in neck tenderness severity. Adverse events were mild and infrequent, and no treatment-related radiographic deterioration was observed.</p><p><strong>Conclusions: </strong>Both RTM and cervical traction were associated with clinical improvement in patients with CDD-related axial neck pain. Confirmatory analyses did not demonstrate robust superiority of RTM for pain or cervical ROM, whereas exploratory analyses suggested faster early improvement and a small cumulative pain benefit with RTM. NTS findings should be interpreted cautiously because the tenderness score has not been formally validated. No serious adverse events were observed.</p><p><strong>Trial registration: </strong>Chinese Clinical Trial Registry, ChiCTR2400082667. Registered retrospectively on 4 April 2024.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2697380"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual reality and perioperative anxiety: a randomized controlled trial.","authors":"Mouna Ouaz, Zayati Mohamed, Khalifa Issam, Bannour Imen, Attia Hela, Majdoub Ali","doi":"10.1080/19932820.2026.2616840","DOIUrl":"10.1080/19932820.2026.2616840","url":null,"abstract":"<p><p>Preoperative anxiety is a feeling of insecurity, physical and psychological discomfort that arises from the prospect of undergoing surgery. Managing anxiety is a therapeutic cornerstone in anesthetic care. Virtual reality has shown a significant effect on managing anxiety and pain by leveraging the principle of distraction, hypnosis, or a combination of distraction and relaxation. We aim to study the impact of virtual reality on perioperative anxiety during surgeries performed under regional anesthesia. This was a monocentric, prospective, randomized study conducted over a three-month period from March 2023 to May 2023 in the anesthesia and resuscitation department of Taher Sfar Hospital in Mahdia. A total of 72 patients scheduled for orthopedic surgeries were included. Patients were randomized to be allocated to: VR+ group (<i>n</i> = 36), who experienced virtual reality during the operation, or the VR- group (<i>n</i> = 36), who did not experience virtual reality. The consumption of anxiolytics (Midazolam) was evaluated intraoperatively along with perioperative anxiety levels (ICD-11 code MB24.6). Anxiety levels were assessed using the STAI-6, and LIKERT scales. Patient satisfaction was measured using the LIKERT scale. Data from 68 patients were analyzed, with 34 patients in each group. Our study showed that there were no significant differences in preoperative anxiety levels between the groups (average STAI-6 score: VR- = 43.2 vs. VR+ = 44.8). Virtual reality reduced the frequency of anxiolytic use intraoperatively: 61.7% in the VR- group vs. 5.8% in the VR+ group (<i>p</i> < 0.001), as well as the quantity used. Postoperative anxiety reduction was comparable between groups. All patients included in the study exhibited very low anxiety levels according to the STAI-6 score, taking preoperative anxiety levels into account. Virtual reality can be considered an effective method for managing perioperative anxiety during surgeries under regional anesthesia and helps prevent postoperative complications.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"21 1","pages":"2616840"},"PeriodicalIF":2.5,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12821343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}