Libyan Journal of Medicine最新文献

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The effect of rebound exercise on cognition and balance of females with overweight and obesity.
IF 1.8 4区 医学
Libyan Journal of Medicine Pub Date : 2025-12-01 Epub Date: 2024-12-06 DOI: 10.1080/19932820.2024.2438513
Chidiebele Petronilla Ojukwu, Izuchukwu Simeon Nnyaba, Stephen Sunday Ede, Adaora Justina Okemuo, Judith Amaka Enebe
{"title":"The effect of rebound exercise on cognition and balance of females with overweight and obesity.","authors":"Chidiebele Petronilla Ojukwu, Izuchukwu Simeon Nnyaba, Stephen Sunday Ede, Adaora Justina Okemuo, Judith Amaka Enebe","doi":"10.1080/19932820.2024.2438513","DOIUrl":"10.1080/19932820.2024.2438513","url":null,"abstract":"<p><p>Balance issues have been reported to be common among females with overweight or obesity with associated fall risks. Despite the increasing reports of the negative impacts of obesity on balance and cognition, there is a scarcity of research aimed at evaluating effective interventions. To examine the effects of rebound exercises on cognition and balance among females with overweight and obesity. This Quasi-experimental study used the purposive sampling method to recruit 20 female students (aged 17-35 years) with overweight and obese at the Evangel University Akaeze, Ebonyi State Nigeria. Rebound exercise intervention was administered to all participants at the gym for 30 minutes in each session, three times a week for six weeks, while their cognitive performances, stationary balance, and dynamic balance were measured pre-and post-trial using Trail Marking Test Apparatuses, Unilateral Pedal Tests, and Meter Backward Walk Test respectively. There was a significant (<i>p</i> < 0.001) difference in the participants' cognition values across weeks 1, 3, and 6 with a progressive improvement over time. There was also a significant (<i>p</i> < 0.05) difference in the participants' static and dynamic balance values across weeks 1, 3, and 6 with a progressive improvement in balance performance over time. Rebound exercise significantly improved the cognition and balance of females with overweight or obese. This finding suggests a promising intervention to improve balance and cognitive-related problems in this population. Registered retrospectively in the Pan African Clinical Trial Registry, identification number for the registry is PACTR202405746557031. Dated 2 May 2024.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"20 1","pages":"2438513"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-effectiveness of prevention program for type 2 diabetes mellitus in high risk patients in the Republic of Srpska, Bosnia and Herzegovina.
IF 1.8 4区 医学
Libyan Journal of Medicine Pub Date : 2025-12-01 Epub Date: 2024-12-15 DOI: 10.1080/19932820.2024.2437226
Dragana Grujić-Vujmilović, Kristina Veljković, Živana Gavrić, Snježana Popović-Pejičić
{"title":"Cost-effectiveness of prevention program for type 2 diabetes mellitus in high risk patients in the Republic of Srpska, Bosnia and Herzegovina.","authors":"Dragana Grujić-Vujmilović, Kristina Veljković, Živana Gavrić, Snježana Popović-Pejičić","doi":"10.1080/19932820.2024.2437226","DOIUrl":"https://doi.org/10.1080/19932820.2024.2437226","url":null,"abstract":"<p><p>The Republic of Srpska (RS), as a part of the Western Balkans (WB) region, has a higher diabetes prevalence than the EU. This study aims to assess the cost-effectiveness of early treatment of high-risk patients with pre-diabetes and undiagnosed diabetes in our setting. We designed a Markov chain Monte Carlo (MCMC) model which reflects the current International Diabetes Federation (IDF) three-step plan for the prevention of T2DM in those at increased risk. The model captures the evolution of the disease in FINDRISC high-risk patients from normal glucose tolerance (NGT) to impaired fasting glucose (IFG) or impaired glucose tolerance (IGT) and then to T2DM and its complications. We developed two MCMC models, in order to follow the progression of the disease in high-risk cases, ie, when early treatment is undertaken or when it is not undertaken. The health costs and quality adjusted life years (QALY) were discounted at an annual rate of 3%. The key model parameters were varied in one-way and probabilistic sensitivity analysis. Early treatment resulted in increased life expectancy, postponement of the onset of diabetes and increased QALY for all patients. The discounted incremental cost-effectiveness-ratios (ICER) in NGT, IFG, IGT, and T2DM patients were -289.9, 9724.03, -1478.59 and 4084.67 €. In high-risk IGT patients, ICER was the most favorable, being both a cost saving and QALY gaining, with the consistent results confirmed by the sensitivity analysis. The results recommend the acceptance of a new health policy of identifying IGT patients with the use of FINDRISC questionnaire and plasma glucose measurements; providing them with a lifestyle change program; and implementing intensive diabetes treatment, as their disease progresses. Our results are especially significant for the Western Balkan countries, since this was the first cost-effectiveness study of T2DM prevention in this region.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"20 1","pages":"2437226"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A survey into the utilization of probiotics and medicinal plants among individuals afflicted with gastrointestinal disorders in healthcare institutions in Saïda, Algeria. 对阿尔及利亚赛达市医疗机构中胃肠道疾病患者使用益生菌和药用植物情况的调查。
IF 2.4 4区 医学
Libyan Journal of Medicine Pub Date : 2024-12-31 Epub Date: 2024-02-18 DOI: 10.1080/19932820.2024.2317492
Lamia Abir Tazi, Yasmina Benabdesslem, Sabrina Amara, Kadda Hachem
{"title":"A survey into the utilization of probiotics and medicinal plants among individuals afflicted with gastrointestinal disorders in healthcare institutions in Saïda, Algeria.","authors":"Lamia Abir Tazi, Yasmina Benabdesslem, Sabrina Amara, Kadda Hachem","doi":"10.1080/19932820.2024.2317492","DOIUrl":"10.1080/19932820.2024.2317492","url":null,"abstract":"<p><p><b>Aim:</b> Functional gastrointestinal (GI) disorders are recognized as a major public health concern worldwide. These disorders involve persistent digestive symptoms indicative of digestive tract dysfunction.<b>Materials and Methods:</b> A survey examining the utilisation of probiotics and medicinal plants as supplementary treatments was conducted on 160 patients with GI disorders at healthcare institutions in Saïda from March to April 2023 using questionnaires that had been previously adapted and tested for reliability with Cronbach's alpha test. Raw data collected through the questionnaires were transferred to a database and analysed using SPSS software.<b>Results:</b> Overall, 49.38% of participants possessed knowledge of or actively utilised probiotics; such awareness was strongly associated with the participants' educational attainment (<i>p</i> = 0.029). The noteworthy probiotic supplements were Biocharbon (36.09%), Lactocil (15.38%), Smebiocta (13.61%), Ultrabiotic Adult (12.43%), Effidigest (12.43%), and Ultralevure (7.69%). During crisis, individuals tended to consume natural goods rich in probiotics, including yoghurt (13.26%) and fermented milk (8.60%), as well as foods rich in prebiotic fibre, including vegetables (18.99%), fruits (13.26%), wheat (9.67%), bran (7.52%), rye (6.81%), and oat flakes (6.45%). Additionally, 77.56% of patients used medicinal plants during crises, with <i>Mentha spicata</i> (12.2%), <i>Thymus vulgaris</i> (11.3%), <i>Pimpinella anisum</i> (8.5%), <i>Cuminum cyminum</i> (8.0%), <i>Punica granatum</i> (7.8%), <i>Trachyspermum ammi</i> (7.5%), and <i>Senna acutifolia</i> (7.0%) being the more commonly favoured options in phytotherapy. The main focus of these herbs was to alleviate bloating (57%), constipation (30.12%), and diarrhoea (12.87%) (<i>p</i> < 0.001). The most frequently utilised plant parts were leaves (47.30%), seeds (25.21%), and bark (13.21%). Most patients (82.91%) favoured infusion as their preferred consumption method, and approximately 85.43% believed in phytotherapy's ability to extend symptomatic relief.<b>Conclusion:</b> The understanding of probiotics is still in its infancy, whereas phytotherapy is more widely accepted by patients. Nonetheless, patients are open to the exploration of natural alternatives to conventional medicines.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2317492"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10878339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139900765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do-not-attempt resuscitation policy reduced in-hospital cardiac arrest rate and the cost of care in a developing country. 发展中国家的 "不尝试复苏 "政策降低了院内心脏骤停发生率和护理成本。
IF 2.4 4区 医学
Libyan Journal of Medicine Pub Date : 2024-12-31 Epub Date: 2024-02-25 DOI: 10.1080/19932820.2024.2321671
David O Alao, Snaha M Abraham, Nada Mohammed, George D Oduro, Mohammed A Farid, Roxanne M Roby, Chris Oppong, Arif A Cevik
{"title":"Do-not-attempt resuscitation policy reduced in-hospital cardiac arrest rate and the cost of care in a developing country.","authors":"David O Alao, Snaha M Abraham, Nada Mohammed, George D Oduro, Mohammed A Farid, Roxanne M Roby, Chris Oppong, Arif A Cevik","doi":"10.1080/19932820.2024.2321671","DOIUrl":"10.1080/19932820.2024.2321671","url":null,"abstract":"<p><p>We aim to study the characteristics and outcomes of patients with a Do-Not-Attempt Resuscitation and to determine its impact on the Cost of In-Hospital Cardiac Arrest. A retrospective study of all adult patients admitted to the hospital from June 2021 to May 2022 who had a Do-Not-Resuscitate order. We abstracted patients' socio-demographics, physiologic parameters, primary diagnosis, and comorbidities from the electronic medical records. We calculated the potential economic cost using the median ICU length of stay for the admitted IHCA patients during the study period. There were 28,866 acute admissions over the study period, and 788 patients had DNR orders. The median (IQR) age was 71 (55-82) years, and 50.3% were males. The most prevalent primary diagnosis was sepsis, 426 (54.3%), and cancer was the most common comorbidity. More than one comorbidities were present in 642 (80%) of the cohort. Of the DNR patients, 492 (62.4%) died, while 296 (37.6%) survived to discharge. Cancer was the primary diagnosis in 65 (22.2%) of those who survived, compared with 154 (31.3%) of those who died (P = 0.002). Over the study period, 153 patients had IHCA and underwent CPR, with an IHCA rate of 5.3 per 1,000 hospital admissions. Without a DNR policy, an additional 492 patients with cardiac arrest would have had CPR, resulting in an IHCA rate of 22.3 per 1000 hospital admissions. Most DNR patients in our setting had sepsis complicated by multiple comorbidities. The DNR policy reduced our IHCA incidence by 76% and prevented unnecessary post-resuscitation ICU care.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2321671"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10898264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139974243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of multi-drug resistant bacteria in intensive care units at Tripoli University Hospital, Tripoli, Libya. 利比亚的黎波里,的黎波里大学医院重症监护室耐多药细菌的流行情况。
IF 2.4 4区 医学
Libyan Journal of Medicine Pub Date : 2024-12-31 Epub Date: 2024-05-08 DOI: 10.1080/19932820.2024.2348235
Khaled Ibrahim, Dalal Thwood, Hajer ELgheriani, Mohamed Salem, Zaynab Elgadiym, Ahmed Zaghdani, Inas Alhudiri, Abdulraouf Habibi, Abdurrezagh Elfahem, Saadeddin Belaid, Otman Ermithi, Mahmoud Almaghrabi, Abubaker ELmaryul, Suad Almadah, Abdunnabi Rayes, Salah Edin El Meshri, Allaaeddin El Salabi, Adam Elzagheid
{"title":"Prevalence of multi-drug resistant bacteria in intensive care units at Tripoli University Hospital, Tripoli, Libya.","authors":"Khaled Ibrahim, Dalal Thwood, Hajer ELgheriani, Mohamed Salem, Zaynab Elgadiym, Ahmed Zaghdani, Inas Alhudiri, Abdulraouf Habibi, Abdurrezagh Elfahem, Saadeddin Belaid, Otman Ermithi, Mahmoud Almaghrabi, Abubaker ELmaryul, Suad Almadah, Abdunnabi Rayes, Salah Edin El Meshri, Allaaeddin El Salabi, Adam Elzagheid","doi":"10.1080/19932820.2024.2348235","DOIUrl":"10.1080/19932820.2024.2348235","url":null,"abstract":"<p><p>Among hospitalized patients worldwide, infections caused by multidrug-resistant (MDR) bacteria are a major cause of morbidity and mortality. This study aimed to isolate MDR bacteria from five intensive care units (ICUs) at Tripoli University Hospital (TUH). A prospective cross-sectional study was conducted over a seven-month period (September 2022 to March 2023) across five ICUs at TUH. A total of 197 swabs were collected from Patients', healthcare workers' and ICUs equipment. Samples collected from patients were nasal swabs, oral cavity swabs, hand swabs, sputum specimens, skin swabs, umbilical venous catheter swabs, and around cannula. Swabs collected from health care workers were nasal swabs, whereas ICUs equipment's samples were from endotracheal tubes, oxygen masks, and neonatal incubators. Identification and antimicrobial susceptibility test was confirmed by using MicroScan auto SCAN 4 (Beckman Coulter). The most frequent strains were Gram negative bacilli 113 (57.4%) with the predominance of <i>Acinetobacter baumannii</i> 50/113 (44%) followed by <i>Klebsiella pneumoniae</i> 44/113 (40%) and <i>Pseudomonas aeruginosa</i> 6/113 (5.3%). The total Gram positive bacterial strains isolated were 84 (42.6%), coagulase negative <i>Staphylococci</i> 55 (66%) with MDRs (89%) were the most common isolates followed by <i>Staphylococcus aureus</i> 15 (17.8%). Different antibiotics were used against these isolates; Gram- negative isolates showed high resistance rates to ceftazidime, gentamicin, amikacin and ertapenem. <i>A. baumannii</i> were the most frequent MDROs (94%), and the highest resistance rates in Gram-positive strains were observed toward ampicillin, oxacillin, ampicillin/sulbactam and Cefoxitin, representing 90% of total MDR Gram-positive isolates. ESBL and MRS were identified in most of strains. The prevalence of antibiotic resistance was high for both Gram negative and Gram positive isolates. This prevalence requires strict infection prevention and control intervention, continuous monitoring, implementation of effective antibiotic stewardship, immediate, concerted and collaborative action to monitor its prevalence and spread in the hospital.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2348235"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11080667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Ramadan on cognitive functions in young boys. 斋月对男孩认知功能的影响
IF 2.4 4区 医学
Libyan Journal of Medicine Pub Date : 2024-12-31 Epub Date: 2024-01-09 DOI: 10.1080/19932820.2024.2301830
Amira Miladi, Mohamed Ali Saafi, Imed Latiri
{"title":"Effects of Ramadan on cognitive functions in young boys.","authors":"Amira Miladi, Mohamed Ali Saafi, Imed Latiri","doi":"10.1080/19932820.2024.2301830","DOIUrl":"10.1080/19932820.2024.2301830","url":null,"abstract":"<p><p>Fasting during Ramadan involves abstaining from food and drink from dawn to sunset, potentially influencing cognitive functions essential for the intellectual development of the youth. Therefore, understanding the effects of fasting on these functions in children/adolescents provides valuable perspectives to enhance education and promote mental well-being. However, studies on children/adolescents in this context are still limited. To evaluate the impact of Ramadan fasting on cognitive functions, including information processing speed, inhibition, decision-making, and auditory attention processes among children and adolescents aged 11 to 15 years. This study was conducted with 24 healthy children/adolescents (aged 12.84 ± 0.69 years). The experimental protocol consisted of two sessions: Before-Ramadan (BR) and at the beginning of the second week of Ramadan (R2). At each session, the boys were randomly tested on simple reaction time (SRT), choice reaction time (CRT), negative priming reaction time (NPRT), and auditory discrimination (P300). The tests were administered and scored by the same person in the different sessions. The study found that Ramadan fasting did not have an effect on various reaction times or on electro-physiological data, including P300 amplitude and latency. The current study, conducted with healthy children/adolescents, indicates that Ramadan fasting had no impact on various reaction times (SRT, CRT, NPRT), suggesting the preservation of information processing speed and decision-making, even in the face of increased task complexity. This is evident, on the one hand, through the maintenance of the ability to react to unexpected events, and, on the other hand, through the mastery of resistance to automatism, thus reflecting the preservation of inhibitory function (NPRT). Regarding P300 data, the absence of changes in latencies and amplitudes suggests that Ramadan fasting did not alter either the evaluation time of auditory stimuli or auditory attention processes.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2301830"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10786423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors influencing fatigue among patients undergoing hemodialysis: a multi-center cross-sectional study. 影响血液透析患者疲劳的因素:一项多中心横断面研究。
IF 2.4 4区 医学
Libyan Journal of Medicine Pub Date : 2024-12-31 Epub Date: 2024-01-09 DOI: 10.1080/19932820.2023.2301142
Bushra Alshammari, Sameer A Alkubati, Awatif Alrasheeday, Eddieson Pasay-An, J Silvia Edison, Norah Madkhali, Ahmed K Al-Sadi, Maha Salem Altamimi, Sahar Obeid Alshammari, Areej A Alshammari, Farhan Alshammari
{"title":"Factors influencing fatigue among patients undergoing hemodialysis: a multi-center cross-sectional study.","authors":"Bushra Alshammari, Sameer A Alkubati, Awatif Alrasheeday, Eddieson Pasay-An, J Silvia Edison, Norah Madkhali, Ahmed K Al-Sadi, Maha Salem Altamimi, Sahar Obeid Alshammari, Areej A Alshammari, Farhan Alshammari","doi":"10.1080/19932820.2023.2301142","DOIUrl":"10.1080/19932820.2023.2301142","url":null,"abstract":"<p><p>Fatigue has been reported to be the most common symptom experienced by patients receiving hemodialysis (HD) therapy. Fatigue can lead to a reduction in their ability to engage in both routine and self-care activities, which can negatively affect their self-confidence and quality of life. This study aimed to determine the level of fatigue and the factors that affecting its level among patients receiving uHD.</p><p><strong>Methods: </strong>A cross-sectional design was utilized to explore the level of fatigue among patients receiving maintenance HD using the Mul-tidimensional Assessment of Fatigue (MAF) scale. Data were collected from four dialysis centers in two Saudi Arabia cities, Hail and Al-Qassim, between January 2022 and October 2022.</p><p><strong>Results: </strong>The questionnaire was completed by 236 patients. Older patients, male patients, and retired pa-tients reported significantly higher levels of fatigue (<i>p</i> < 0.001). In contrast, marital status, educational level, and financial status did not significantly affect the level of fatigue among patients (<i>p</i> = 0.193, 0.285, and 0.126, respectively). Patients who had seven or more dependents reported more fatigue than those who had lower levels of fatigue or who did not have dependents (<i>p</i> = 0.004). In addition, patients who had a regular exercise regimen reported significantly lower fatigue than those who did not have an exercise regimen (<i>p</i> = 0.011). Multiple linear regression demonstrated that employment status (student), comorbidity condition (one chronic disease), dialysis duration, satisfaction with dialysis time, and dialysis time were found to affect the fatigue scores (R2 = 0.302, p ˂ 0.001).</p><p><strong>Conclusion: </strong>The findings of this study gives a broader understanding of factors influencing fatigue among patients with HD that will help to develop strategies of more focused interventions to reduce fatigue among patients with HD.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2301142"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10786431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between serum Midkine and Omentin-1 levels and the severity of sepsis in patients and their prognostic value. 患者血清 Midkine 和 Omentin-1 水平与败血症严重程度的关系及其预后价值。
IF 1.8 4区 医学
Libyan Journal of Medicine Pub Date : 2024-12-31 Epub Date: 2024-07-23 DOI: 10.1080/19932820.2024.2383025
Lin Gao, Qindi Liu, Zhiming Kuang, Shanbin Yuan
{"title":"Relationship between serum Midkine and Omentin-1 levels and the severity of sepsis in patients and their prognostic value.","authors":"Lin Gao, Qindi Liu, Zhiming Kuang, Shanbin Yuan","doi":"10.1080/19932820.2024.2383025","DOIUrl":"10.1080/19932820.2024.2383025","url":null,"abstract":"<p><p>To explore the relationship between serum levels of midkine and omentin-1 and the severity of sepsis in patients, and their prognostic value. A retrospective analysis was conducted on the clinical data of 180 sepsis patients. According to the severity of the patient's condition, they were separated into sepsis group (<i>n</i> = 76), severe sepsis group (<i>n</i> = 59), and sepsis shock group (<i>n</i> = 45). Based on the survival within 28 days of admission, they were grouped into survivors group (<i>n</i> = 128) and nonsurvivors group (<i>n</i> = 52). The serum Midkine level and APACHE II score in the sepsis shock group were higher than those in the severe sepsis group and sepsis group, while the Omentin-1 level was lower than that in the severe sepsis group and sepsis group (<i>p</i> < 0.05). The serum Midkine level and APACHE II score in the severe sepsis group were higher than those in the sepsis group, while the Omentin-1 level was lower than that in the sepsis group (<i>p</i> < 0.05). The Midkine and APACHE II score in the nonsurvivors group was higher than those in the survivors group, while the Omentin-1 score was lower than that in the survivors group (<i>p</i> < 0.05). Midkine and APACHE II score were independent risk factors for the prognosis of sepsis patients, while Omentin-1 was a protective factor for the prognosis of sepsis patients (<i>p</i> < 0.05). The AUC of the combined prediction of serum Midkine and Ommentin-1 for the prognosis of sepsis patients was 0.880, with a sensitivity of 90.38% and a specificity of 72.66%. The combined prediction of serum Midkine and Ommentin-1 was better than that of individual prediction of Midkine and Ommentin-1. Serum Midkine is highly expressed and Omentin-1 is lowly expressed in sepsis patients, and the combination of the two has a high predictive power for the prognosis of sepsis patients.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2383025"},"PeriodicalIF":1.8,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11268220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Implementing Electronic Nursing Records on Quality and Safety Indicators in Care. 实施电子护理记录对护理质量和安全指标的影响。
IF 1.8 4区 医学
Libyan Journal of Medicine Pub Date : 2024-12-31 Epub Date: 2024-11-21 DOI: 10.1080/19932820.2024.2421625
Manel Chouchene Douma, Mohamed Ben Rejeb, Najet Zardoub, Ahlem Braham, Houda Chouchene, Olfa Bouallegue, Houyem Said Latiri
{"title":"Impact of Implementing Electronic Nursing Records on Quality and Safety Indicators in Care.","authors":"Manel Chouchene Douma, Mohamed Ben Rejeb, Najet Zardoub, Ahlem Braham, Houda Chouchene, Olfa Bouallegue, Houyem Said Latiri","doi":"10.1080/19932820.2024.2421625","DOIUrl":"10.1080/19932820.2024.2421625","url":null,"abstract":"<p><p>Electronic Health Records (EHR) have been adopted to improve the quality of care. Despite the growing use of health information technology, nursing documentation remains a challenge. In Tunisia, the implementation of the Electronic Medical Record (EMR) system is gaining momentum as part of national initiatives to modernize healthcare. However, nursing documentation is still largely paper-based, and no studies in Tunisia have adressed this topic. This research aims to assess the effect of the Electronic Nursing Record (ENR) on the quality and safety of care indicators (QSCI). This is an interventional study structured in four phases: development, pre-implementation, implementation, and evaluation, integrating the principles of the 'Standards for Reporting Implementation Studies' (StaRI). A list of QSCI was defined and validated through a literature review and Delphi consensus. The impact of the ENR on these indicators was evaluated in a Tunisian university hospital through a quasi-experimental study. Indicators were measured before ENR, one month after, and six months after. Data analyses was conducted using SPSS with statistical tests. Initially, the study led to the identification and validation of seventeen QSCI. Subsequently, a quasi-experimental study was conducted to evaluate the impact of ENR implementation on these indicators. The results revealed a significant improvement in the intervention group (using ENR), particularly in the traceability of vital signs (p < 10⁻<sup>3</sup>) and infusion administration (p = 0.027). Conversely, the control group (using paper-based documentation) performed better in terms of traceability of inter-team handovers (95.1% compared to 71.9% for the intervention group). The electronic documentation system is seen as a major transformation in healthcare in many hospitals worldwide. Moreover, electronic nursing documentation is crucial for patient safety. Its implementation in our hospital revealed a positive impact of the ENR on certain aspects of care quality while highlighting gaps in inter-team handovers.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2421625"},"PeriodicalIF":1.8,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11583327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of human rhinovirus in COPD exacerbations in Abu Dhabi: molecular epidemiology and clinical significance. 人类鼻病毒在阿布扎比慢性阻塞性肺病恶化中的作用:分子流行病学和临床意义。
IF 1.8 4区 医学
Libyan Journal of Medicine Pub Date : 2024-12-31 Epub Date: 2024-01-30 DOI: 10.1080/19932820.2024.2307679
Ahmad R Alsayed, Anas Abed, Heba A Khader, Luai Hasoun, Mohammed Al Maqbali, Mahmoud J Al Shawabkeh
{"title":"The role of human rhinovirus in COPD exacerbations in Abu Dhabi: molecular epidemiology and clinical significance.","authors":"Ahmad R Alsayed, Anas Abed, Heba A Khader, Luai Hasoun, Mohammed Al Maqbali, Mahmoud J Al Shawabkeh","doi":"10.1080/19932820.2024.2307679","DOIUrl":"10.1080/19932820.2024.2307679","url":null,"abstract":"<p><p>This study aimed to describe the molecular epidemiology and seasonality of human rhinovirus (HRV) in chronic obstructive pulmonary disease (COPD) and its association with COPD exacerbations in Abu Dhabi, the United Arab Emirates (UAE). Sputum specimens were collected for analysis from all COPD patients who visited a medical center from November 2021 to October 2022. The real-time quantitative polymerase chain reaction (qPCR) test was used to detect HRV. Of the 78 COPD patients included in the study, 58 (74%) patients presented with one or more exacerbation episodes. The incidence of COPD exacerbation peaked over the winter and substantially decreased during the summer. HRV positivity in patients during exacerbation (E1) was 11/58 (19%) and 15/58 (26%) two weeks after the exacerbation episode (E2). There was no significant difference in the HRV load in these patients. No statistically significant difference was observed in the detection of HRV during exacerbation compared to patients with stable COPD. This is the first study to assess the association between HRV detection by qPCR and COPD exacerbations in the UAE. The high sensitivity of the detection technology helped collect reliable epidemiologic data. Few studies have provided similar Middle East data. This study's pattern of COPD exacerbations and HRV detection parallels that of temperate countries. This information can help with future, more extensive surveillance of respiratory viruses in the UAE and the Middle East and their association with COPD exacerbations.</p>","PeriodicalId":49910,"journal":{"name":"Libyan Journal of Medicine","volume":"19 1","pages":"2307679"},"PeriodicalIF":1.8,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139643179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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