Luminescence最新文献_第5页

Unlocking Pranoprofen's Hidden Glow: β-Cyclodextrin-Driven Fluorescence Amplification of Pranoprofen for Pharmaceutical and Biological Analysis 解锁普诺洛芬的隐藏光芒：β-环糊精驱动的普诺洛芬荧光扩增用于药物和生物分析。

IF 3 4区化学

Luminescence Pub Date : 2026-03-06 DOI: 10.1002/bio.70461

Aya Magdy Saad, Jenny Jeehan Mohamed Nasr, Asmaa Kamal El-Deen

{"title":"Unlocking Pranoprofen's Hidden Glow: β-Cyclodextrin-Driven Fluorescence Amplification of Pranoprofen for Pharmaceutical and Biological Analysis","authors":"Aya Magdy Saad, Jenny Jeehan Mohamed Nasr, Asmaa Kamal El-Deen","doi":"10.1002/bio.70461","DOIUrl":"10.1002/bio.70461","url":null,"abstract":"<div>\u0000 \u0000 <p>This study introduces a novel approach for enhancing the inherent native fluorescence of pranoprofen, a nonsteroidal anti-inflammatory drug (NSAID), commonly used to treat allergic conjunctivitis. The fluorescence was significantly amplified when pranoprofen was encapsulated within the hydrophobic cavity of β-cyclodextrin, which provided a favorable microenvironment that stabilized its protonated form. The enhanced fluorescence intensity was measured at 404 nm following excitation at 273 nm with a large Stokes shift of around 130 nm. The method was validated following ICH guidelines and demonstrated excellent linearity over a concentration range of 0.10–6.0 μg/mL, with a correlation coefficient of 0.9999 and a low limit of detection (LOD) of 0.034 μg/mL. The proposed method was effectively applied for the analysis of pranoprofen in ophthalmic solutions and aqueous humor, yielding recoveries ranging from 98.9 to 101.1%. Furthermore, multifaceted sustainability assessment tools confirmed the method's eco-sustainability. This analytical strategy offers a reliable, rapid, and eco-friendly solution for the routine analysis of pranoprofen in pharmaceutical and clinical analysis.</p>\u0000 </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"41 3","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrazone-Derived Schiff Bases as Dual-Mode Sensors: Fluorescence Turn-On Detection of Zn2+ and Colorimetric Detection of Zn2+ and Cu2+ Ions 腙衍生的希夫碱作为双模传感器：Zn2+的荧光开启检测和Zn2+和Cu2+离子的比色检测。

IF 3 4区化学

Luminescence Pub Date : 2026-03-06 DOI: 10.1002/bio.70456

Aditya C P, Haritha C, Swathi M, Chinna Ayya Swamy P

{"title":"Hydrazone-Derived Schiff Bases as Dual-Mode Sensors: Fluorescence Turn-On Detection of Zn2+ and Colorimetric Detection of Zn2+ and Cu2+ Ions","authors":"Aditya C P, Haritha C, Swathi M, Chinna Ayya Swamy P","doi":"10.1002/bio.70456","DOIUrl":"10.1002/bio.70456","url":null,"abstract":"<div>\u0000 \u0000 <p>Three novel Schiff base chemosensors (<b>HZ-1</b>, <b>HZ-2</b>, and <b>HZ-3</b>) were synthesized by condensing 4-hydroxy-[1,1′-biphenyl]-3-carbaldehyde with distinct hydrazine derivatives: (Z)-(anthracen-9-ylmethylene)hydrazine, (Z)-(pyren-1-ylmethylene)hydrazine, and (Z)-4-(hydrazonomethyl)-N,N-diphenylaniline. Structural variation was confined to the hydrazine moiety, enabling a systematic investigation of its influence on photophysical and sensing properties. UV-Vis absorption and fluorescence studies revealed marked differences in optical behavior, with <b>HZ-1</b> and <b>HZ-3</b> chemosensors showing significant fluorescence enhancement upon selective metal ion binding as compared with <b>HZ-2</b>. The limit of detection (LOD) for each sensor was in the micromolar range, confirming their high sensitivity. Job's plot analysis indicated a predominant 2:1 ligand-to-metal stoichiometry. Complementary density functional theory (DFT) calculations provided insights into frontier molecular orbitals and electron density distributions, rationalizing the observed spectral variations. Overall, this study demonstrates how precise modification of the hydrazine fragment can tailor the electronic environment and sensing performance of Schiff bases, offering valuable design strategies for efficient fluorescent metal ion chemosensors.</p>\u0000 </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"41 3","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Near-Infrared Off–On Fluorescent Probe for Sensitive and Specific Imaging of Fibroblast Activation Protein-α Activity in Pancreatic Cancer 近红外开关荧光探针对胰腺癌成纤维细胞活化蛋白-α活性的敏感和特异性成像。

IF 3 4区化学

Luminescence Pub Date : 2026-03-05 DOI: 10.1002/bio.70430

Jiao Xu, Yutong Li, Zhipeng Li, Jianliang Shen, Bo Peng

{"title":"A Near-Infrared Off–On Fluorescent Probe for Sensitive and Specific Imaging of Fibroblast Activation Protein-α Activity in Pancreatic Cancer","authors":"Jiao Xu, Yutong Li, Zhipeng Li, Jianliang Shen, Bo Peng","doi":"10.1002/bio.70430","DOIUrl":"10.1002/bio.70430","url":null,"abstract":"<div>\u0000 \u0000 <p>Fibroblast activation protein-α (FAP-α) is a crucial biomarker for pancreatic cancer, yet developing activatable near-infrared (NIR) fluorescent probes for its real-time imaging faces challenges in achieving high signal-to-background ratios and specificity. Here, we present <b>ZGP-D</b>, a novel FAP-α-activated NIR probe designed to overcome these limitations. <b>ZGP-D</b> integrates a DDAO fluorophore with a FAP-α-specific Cbz–Gly–Pro peptide, creating an efficient intramolecular charge transfer (ICT) quenching mechanism that ensures a minimal background signal. Upon specific enzymatic cleavage by FAP-α, the probe exhibits a robust > 40-fold fluorescence turn-on at 657 nm, demonstrating exceptional sensitivity with a detection limit of 0.024 μg/mL and superior selectivity over various biological interferents. <b>ZGP-D</b> successfully visualized endogenous FAP-α in living cells, clearly distinguishing high-expression pancreatic cancer cells (BXPC-3) from low-expression cells. Furthermore, in a BXPC-3 xenograft mouse model, local administration of <b>ZGP-D</b> enabled high-contrast tumor imaging, achieving a tumor-to-normal tissue signal ratio of 4.2. This work establishes <b>ZGP-D</b> as a highly sensitive and specific molecular tool for monitoring FAP-α activity, highlighting its significant potential for advancing cancer diagnostics and fluorescence-guided surgery.</p>\u0000 </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"41 3","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Luminescent Dyes From Waste Source: Futuristic Advanced Material for Bioimaging and Sensing 来自废物来源的发光染料：生物成像和传感的未来先进材料。

IF 3 4区化学

Luminescence Pub Date : 2026-02-24 DOI: 10.1002/bio.70458

Vishu Sharma, R. K. Soni, Nazia Tarannum, Neha Mittal, Prerna Kaushik

{"title":"Luminescent Dyes From Waste Source: Futuristic Advanced Material for Bioimaging and Sensing","authors":"Vishu Sharma, R. K. Soni, Nazia Tarannum, Neha Mittal, Prerna Kaushik","doi":"10.1002/bio.70458","DOIUrl":"10.1002/bio.70458","url":null,"abstract":"<div>\u0000 \u0000 <p>The development of luminescent dyes from waste sources represents a sustainable and cost-effective alternative to conventional dyes, addressing environmental concerns while offering advanced functionality for bioimaging and sensing applications. Traditional luminescent materials often suffer from high toxicity, low biocompatibility, and photostability issues. Recent research has explored the synthesis of luminescent dyes from agricultural, industrial, and synthetic waste, leading to materials with improved quantum yields, stability, and reduced environmental impact. This review explores luminescent dyes from conventional organic fluorophores to waste-derived nano-dyes (CDs, QDs, UCNPs) and their applications in bioimaging and chemical sensing. Advances in silica nanoparticle–based luminescent systems, quantum dots, upconversion nanoparticles, metal–organic complexes, and hybrid dye systems have significantly enhanced optical properties and biocompatibility. Waste-derived carbon quantum dots and other nanostructured materials have demonstrated promising applications in biomedical imaging, pollutant detection, and environmental monitoring. Despite significant progress, challenges such as scalability, reproducibility, and regulatory considerations remain. The future of luminescent dye research lies in optimizing synthesis methodologies, improving functional properties, and integrating green chemistry principles. This review provides an in-depth analysis of the latest advancements in waste-derived luminescent dyes, their potential applications, and the challenges that must be addressed to facilitate their broader adoption in biomedical and environmental fields.</p>\u0000 </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"41 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Properties of K2SO4:Cu,Na Phosphor as a Novel Sensitive OSL Detector Under Infrared Stimulation 红外刺激下K2SO4:Cu，Na荧光粉灵敏光释光探测器性能的研究。

IF 3 4区化学

Luminescence Pub Date : 2026-02-23 DOI: 10.1002/bio.70457

Renata Majgier, Go Okada

{"title":"Investigation of the Properties of K2SO4:Cu,Na Phosphor as a Novel Sensitive OSL Detector Under Infrared Stimulation","authors":"Renata Majgier, Go Okada","doi":"10.1002/bio.70457","DOIUrl":"10.1002/bio.70457","url":null,"abstract":"<div>\u0000 \u0000 <p>This work presents the dosimetric characteristics of a newly developed phosphor material—potassium sulfate doped with copper and sodium (K<sub>2</sub>SO<sub>4</sub>:Cu,Na). The measurements were carried out using the TORAIMS reader and X-ray irradiation. Detectors based on K<sub>2</sub>SO<sub>4</sub>:Cu,Na were prepared in different forms, including pellets with Teflon as a binder and silicone thin films. The investigation included analysis of OSL excitation and emission spectra, as well as X-ray diffraction (XRD) measurements. The K<sub>2</sub>SO<sub>4</sub>:Cu,Na phosphor demonstrated high sensitivity as a radiation detector within the infrared stimulated luminescence (IRSL) method. Basic IRSL dosimetric properties were studied: signal reproducibility, reusability, dose–response, minimum detectable dose, X-ray energy dependence and fading characteristic. For all types of tested detectors, the dose–response was linear up to 200 mGy and saturated near 20 Gy. The material showed high sensitivity, with minimum detectable doses in the sub-milligray range. Fading effects were noted but could be significantly reduced by preheat treatment. The optimal preheating temperature was identified as 120°C. These findings highlight K<sub>2</sub>SO<sub>4</sub>:Cu,Na as a promising candidate for applications in luminescent dosimetry.</p>\u0000 </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"41 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eco-Friendly Fluorescent Carbon Quantum Dot Nano-Biosensor: a Dual-Function Platform for Sensitive Analysis of Temozolomide and Live-Cell Imaging 生态友好型荧光碳量子点纳米生物传感器：替莫唑胺和活细胞成像敏感分析的双功能平台

IF 3 4区化学

Luminescence Pub Date : 2026-02-23 DOI: 10.1002/bio.70448

Galal Magdy, Basma H. Anwar, Manal A. Alossaimi, Fathalla Belal, Ahmed Emad F. Abbas, Mahmoud A. Tantawy, Aml A. Emam, Raghda A. Emam

{"title":"Eco-Friendly Fluorescent Carbon Quantum Dot Nano-Biosensor: a Dual-Function Platform for Sensitive Analysis of Temozolomide and Live-Cell Imaging","authors":"Galal Magdy, Basma H. Anwar, Manal A. Alossaimi, Fathalla Belal, Ahmed Emad F. Abbas, Mahmoud A. Tantawy, Aml A. Emam, Raghda A. Emam","doi":"10.1002/bio.70448","DOIUrl":"10.1002/bio.70448","url":null,"abstract":"<div>\u0000 \u0000 <p>Temozolomide (TMZ) is an important chemotherapeutic drug, yet its weak native fluorescence hinders direct spectrofluorimetric analysis. Conventional analytical methods are often costly, labor-intensive, and environmentally unfriendly. To overcome these limitations, a novel, eco-friendly spectrofluorimetric method was developed using sulfur and nitrogen co-doped carbon quantum dots (S,N-CQDs) as fluorescent nano-sensors. The nanodots were synthesized via a simple, one-pot microwave-assisted route from natural sources (<i>Colocasia esculenta</i> root and chicken tissue) serving as carbon, sulfur, and nitrogen precursors. The S,N-CQDs exhibited strong blue fluorescence, high stability, and excellent biocompatibility. TMZ induced a selective, concentration-dependent quenching effect, enabling sensitive determination over 0.2–17.0 μg/mL with a detection limit of 0.016 μg/mL. The quenching was visually detectable under UV light and captured using a smartphone camera, allowing a simple, low-cost detection strategy. Validation following ICH Q2 (R2) guidelines confirmed high accuracy (98.00%–101.50% recoveries), precision (RSD ≤ 1.840), and robustness (%RSD ≤ 1.771). Greenness and blueness assessments demonstrated the method's sustainability and practicality. Moreover, the S,N-CQDs enabled intracellular imaging and real-time monitoring of TMZ in cancer cells. This represents the first eco-friendly CQD-based spectrofluorimetric method for TMZ, offering a rapid, sustainable, and dual-function platform for drug analysis and cancer research.</p>\u0000 </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"41 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147300010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Hydroxyl or Methoxy Group in B-Ring of Flavonols on Structural Change and Antiseptic Ability of Soy Protein Isolate 黄酮醇b环羟基或甲氧基对大豆分离蛋白结构变化及防腐能力的影响

IF 3 4区化学

Luminescence Pub Date : 2026-02-21 DOI: 10.1002/bio.70451

Mengyao Guo, Xinru Zhang, Mingyuan Li, Qian Zhang, Jie Liu

{"title":"Effect of Hydroxyl or Methoxy Group in B-Ring of Flavonols on Structural Change and Antiseptic Ability of Soy Protein Isolate","authors":"Mengyao Guo, Xinru Zhang, Mingyuan Li, Qian Zhang, Jie Liu","doi":"10.1002/bio.70451","DOIUrl":"10.1002/bio.70451","url":null,"abstract":"<div>\u0000 \u0000 <p>Soy protein isolate (SPI) enhances the functionality of flavonols, with their interaction and bioactivity critically dependent on B-ring substitution. Multispectral analysis and molecular docking were used to investigate the interaction between SPI and flavonols (Kaempferide (Kaem), Galangin (Gal), Kaempferol (Kae), Myricetin (Myr)) and their resulting antiseptic/antifungal performance. The results indicated that hydroxylation on the B-ring of flavonols significantly enhanced their binding affinity to SPI through static quenching, primarily driven by hydrogen bonds and van der Waals forces, whereas methylation reduced it. Consequently, the binding affinity followed the order of Myr, Kae, Gal, and Kaem. Key functional findings demonstrated a structure–activity relationship: The hydroxyl or methoxy group in B-ring substantially enhanced antibacterial activity in the determination of colony counts. However, for antifungal activity against <i>Gibberella zeae</i> (<i>GZ</i>) and <i>Physalospora piricola</i> (<i>PP</i>), B-ring hydroxylation was unfavorable, whereas methylation was beneficial. Consequently, Gal shows the best antifungal ability, followed by Kaem, Kae, and Myr. A notable discovery was that while pure flavonols or SPI alone promoted <i>GZ</i> growth, their formed flavonol-SPI complexes reversed this effect, exerting inhibitory activity. These insights provide a significant reference for designing natural, green preservative systems by strategically combining specific flavonols with protein carriers like SPI.</p>\u0000 </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"41 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146259621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biowaste-Derived Nitrogen-Doped Carbon Dots for Real-Time Detection of Fe3+ and DFT Mechanistic Study 生物废弃物衍生氮掺杂碳点实时检测Fe3+及DFT机理研究。

IF 3 4区化学

Luminescence Pub Date : 2026-02-21 DOI: 10.1002/bio.70455

Hui Wang, Weixi Fan, Yan Gao, Li Han, Wen He, Chaoyue Shan, Ruixin Zhang, Yuanyuan Du, Xing Gao, Hongcui Li, Wenya Bao, Meng Gao

{"title":"Biowaste-Derived Nitrogen-Doped Carbon Dots for Real-Time Detection of Fe3+ and DFT Mechanistic Study","authors":"Hui Wang, Weixi Fan, Yan Gao, Li Han, Wen He, Chaoyue Shan, Ruixin Zhang, Yuanyuan Du, Xing Gao, Hongcui Li, Wenya Bao, Meng Gao","doi":"10.1002/bio.70455","DOIUrl":"10.1002/bio.70455","url":null,"abstract":"<div>\u0000 \u0000 <p>Nitrogen-doped carbon dots (N-CDs) are emerging as materials for advancing technologies in fields such as environmental analysis, biosensing, and fluorescent probes due to their outstanding fluorescence and excellent biofriendliness. The synthesis of N-CDs involved a facile hydrothermal treatment of agricultural waste bagasse and urea, which acted as the carbon and nitrogen source, respectively. The as-synthesized dots were thoroughly characterized to elucidate the structure and properties, demonstrating that the N-CDs possessed well-defined particle sizes, rich surface functional groups, and promising luminescent characteristics. Specifically, the measured quantum yield was 27.8%. N-CDs exhibit an immediate fluorescence quenching response toward Fe<sup>3+</sup>, and based on this property, a novel sensing platform for real-time Fe<sup>3+</sup> detection was constructed, achieving a limit of detection (LOD) of 0.17 μM. Mechanistic investigations, including fluorescence lifetime decay analysis, temperature-dependent Stern–Volmer studies, and DFT simulations, collectively reveal that the quenching process is primarily governed by dynamic electron transfer from the excited state of N-CDs to the 3d orbital of Fe<sup>3+</sup>. This work not only presents a sustainable and effective fluorescent sensor for Fe<sup>3+</sup> detection but also provides deeper insight into the photophysical interactions between heteroatom-doped carbon dots and metal ions.</p>\u0000 </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"41 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146259658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Energy Transfer in Bioluminescence 生物发光中的能量转移。

IF 3 4区化学

Luminescence Pub Date : 2026-02-19 DOI: 10.1002/bio.70454

Shuangqi Pi, Ya-Jun Liu

{"title":"Energy Transfer in Bioluminescence","authors":"Shuangqi Pi, Ya-Jun Liu","doi":"10.1002/bio.70454","DOIUrl":"10.1002/bio.70454","url":null,"abstract":"<div>\u0000 \u0000 <p>Bioluminescence (BL) is a unique chemiluminescent process in living organisms that has inspired extensive applications in bioimaging and biosensing due to its high sensitivity, non-invasiveness, and absence of background autofluorescence. Most luminescent organisms emit light through a set of luminescent systems. Some luminescent organisms possess an additional antenna protein that can receive energy from the former luminescent system. And the BL is emitted by the antenna protein. Inspired by these natural phenomena, bioluminescence resonance energy transfer (BRET) has been widely exploited to overcome the limitations of native BL, particularly the intensity and short-wavelength emission that restrict deep-tissue imaging. This review summarizes the fundamental mechanisms of ET in representative natural BL systems, combining insights from experimental and theoretical studies. We then conclude recent advances in engineering BRET systems by coupling luciferases with fluorescent proteins, organic dyes, and nanomaterials to achieve brighter and red-shifted emissions, extending into the near-infrared II (NIR-II) region. Finally, we discuss current challenges and propose future directions for developing next-generation BL probes with improved brightness, spectral tunability, and stability. We anticipate that these developments will provide powerful tools for real-time imaging of biological processes with high resolution and penetration depth.</p>\u0000 </div>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"41 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146229575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multilayer 3D AIE Polymers for Selective Fe3+ Detection: Achiral and Chiral Platforms for Environmental Sensing 用于选择性Fe3+检测的多层3D AIE聚合物：用于环境传感的非手性和手性平台

IF 3 4区化学

Luminescence Pub Date : 2026-02-19 DOI: 10.1002/bio.70452

Sai Zhang, Jie Cui, Xueya Zheng, Peng Wang, Zhaoyu Li, Jiaqi Zhang, Bin Zhong

引用次数: 0