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Topology-regulated load transfer mechanisms and mechanical performance of sheet-based TPMS titanium scaffolds. 板基TPMS钛支架的拓扑调节载荷传递机制和力学性能。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-13 DOI: 10.1088/1873-4030/aeb37f
L Fu, Yongzhi Li, Qian Zhang, Ming Liu, Shihao Bi, Ji Yao, Fuyou Wang, Shuai Ma
{"title":"Topology-regulated load transfer mechanisms and mechanical performance of sheet-based TPMS titanium scaffolds.","authors":"L Fu, Yongzhi Li, Qian Zhang, Ming Liu, Shihao Bi, Ji Yao, Fuyou Wang, Shuai Ma","doi":"10.1088/1873-4030/aeb37f","DOIUrl":"https://doi.org/10.1088/1873-4030/aeb37f","url":null,"abstract":"<p><p>Triply periodic minimal surface (TPMS) structures provide a route to control stiffness while retaining pore space, but quantitative links among topology, load transfer, and mechanical response remain limited. This study establishes a topology-load transfer-mechanical response framework by integrating quasi-static compression experiments, Digital Image Correlation, and validated finite element analysis on representative Triply Periodic Minimal Surface titanium scaffolds. The Gyroid-Sheet scaffold exhibits a topology-regulated progressive instability-restabilization deformation mode, distinctly different from the conventional lattice structures exhibiting plateau-dominated yielding behavior. GS20 exhibited experimental Young's modulus and yield strength of 2.26 GPa and 49.6 MPa, whereas FEA predicted 2.68 GPa and 65.43 MPa; therefore, simulations were used only for comparative interpretation. Numerically, its normalized modulus and strength were 13.40 GPa and 327.15 MPa, approximately 36% and 20% higher than PS20, respectively, indicating superior predicted material utilization under identical idealized conditions rather than experimentally validated cross-topology mechanical properties for fabricated TPMS scaffolds. Gibson-Ashby analysis suggests that the Gyroid-Sheet topology retains mechanical efficiency as relative density decreases. A multiscale framework combining elastic anisotropy, principal-stress streamlines, and strain-energy density was then used to interpret how topology governs load transfer and localized mechanical response patterns. The Gyroid-Sheet structure exhibits a near-isotropic elastic response (Zener index = 1.13), along with a higher proportion of stress streamline segments with deflection angle θ < 15° (5.19%) and local turning angle φ < 15° (39.96%), indicating enhanced directional coherence and spatial continuity of load transfer paths. G GS20 testing and comparative simulations suggest that continuous sheet topology promotes load-transfer continuity, material utilization, and resistance to localized energy concentration. These characteristics may support stiffness regulation and load sharing while preserving interconnected pore space for potential fluid and tissue access. The proposed mechanics-based framework therefore provides a basis for screening orthopedic scaffold architectures, although broader experimental validation remains necessary.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Technical evaluation of transport-derived movement trajectories during knee osteoarthritis rehabilitation. 膝关节骨关节炎康复过程中运输源性运动轨迹的技术评价。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-09 DOI: 10.1088/1873-4030/aeac5f
Pooja Kumari Jha, Vikas Kumar, Jagannatha Sahoo, S Kanagaraj
{"title":"Technical evaluation of transport-derived movement trajectories during knee osteoarthritis rehabilitation.","authors":"Pooja Kumari Jha, Vikas Kumar, Jagannatha Sahoo, S Kanagaraj","doi":"10.1088/1873-4030/aeac5f","DOIUrl":"10.1088/1873-4030/aeac5f","url":null,"abstract":"<p><p>Wearable inertial sensors enable repeated movement recording during knee osteoarthritis rehabilitation, but methods for summarizing multivariable changes across routine sessions remain exploratory. This retrospective technical evaluation examined a normalized transport-derived deviation (NTD) constructed from paired shank-mounted inertial measurement units. Seven participants contributed 46 paired-sensor sessions over 45 d. An approximately 30 s active movement segment from each session was divided into 13 windows and represented using 58 time-domain, frequency-domain and cross-sensor features. Session distributions were compared with each participant's first usable sensor session using an archived entropically regularized transport implementation. The output was normalized by the baseline-to-final-session value. Mean NTD values at the scheduled assessment days were 0.00, 0.02, 0.23, 0.63 and 1.00. 14 of the 46 displayed values were structurally constrained baseline or final values; no monotonic constraint was applied to the 32 interior observations, which formed non-decreasing trajectories. At interior scheduled days 5, 15 and 30, absolute differences between mean NTD and participant-adjusted normalized elapsed time were 0.057, 0.076 and 0.019. 21 of the 46 archived calculations reached the 500-iteration limit without meeting the 1 × 10<sup>-6</sup>residual criterion. A log-domain stabilized recomputation of all 46 primary comparisons satisfied a 1 × 10<sup>-8</sup>criterion, with a mean absolute archived-to-stabilized NTD difference of 0.004 (maximum 0.018) across the 32 interior observations. Across support-point counts of 100-1000, interior archived NTD values changed by 0.009-0.026 on average. Routine paired-shank recordings were organized into ordered longitudinal trajectories and the resulting trajectory structure was numerically reproducible under the evaluated implementation. NTD should presently be interpreted as an implementation-specific retrospective coordinate rather than a validated rehabilitation outcome. By defining the requirements for standardized movement tasks, prospective normalization and reproducible sensor placement, these findings provide a practical foundation for prospective validation of transport-based rehabilitation assessment.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149065710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Micro-CT-derived nonlinear micro-finite element estimation of compressive fracture load in murine vertebrae: a pilot feasibility study in sclerostin antibody-treated and control mice. 小鼠椎骨压缩断裂载荷的微ct衍生非线性微有限元估计:在硬化蛋白抗体处理和对照小鼠中进行的初步可行性研究。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-09 DOI: 10.1088/1873-4030/aeb26d
Emil Lodahl Andersen, Frederik Duch Bromer, Christian Lind Nielsen, Annemarie Brüel, Jesper Skovhus Skovhus Thomsen, Daniel Strack, Karupppasamy Subburaj
{"title":"Micro-CT-derived nonlinear micro-finite element estimation of compressive fracture load in murine vertebrae: a pilot feasibility study in sclerostin antibody-treated and control mice.","authors":"Emil Lodahl Andersen, Frederik Duch Bromer, Christian Lind Nielsen, Annemarie Brüel, Jesper Skovhus Skovhus Thomsen, Daniel Strack, Karupppasamy Subburaj","doi":"10.1088/1873-4030/aeb26d","DOIUrl":"https://doi.org/10.1088/1873-4030/aeb26d","url":null,"abstract":"<p><p>Fragility fractures caused by osteoporosis remain a growing health burden, highlighting the need for reliable, non-destructive methods to assess bone strength. We aimed to develop and assess the feasibility of a micro-computed tomography (µCT)-based nonlinear micro-finite element analysis (µFEA) workflow for estimating compressive fracture load in murine vertebrae. Fourth lumbar vertebral bodies from untreated and sclerostin antibody-treated (Scl-Ab) female C57BL/6 mice were imaged ex vivo using µCT and subjected to destructive axial compression testing. µFEA models incorporated heterogeneous isotropic material properties derived from voxel grey values and density-dependent local yield and post-yield softening definitions. µFEA-estimated vertebral fracture load strongly correlated with experimental fracture load (R² = 0.929), while µFEA-estimated axial stiffness showed a moderate-to-high association with experimental values (R2 = 0.70). Across the entire dataset, bone volume fraction (BV/TV) was also strongly associated with experimental fracture load (R2 = 0.928). After treatment stratification, associations were substantially weaker, with µFEA showing a numerically stronger association than BV/TV in the control group (R2 = 0.323 vs. 0.049 but not in the Scl-Ab-treated group (R2 = 0.231 vs. 0.035). This pilot study demonstrates the technical feasibility of nonlinear heterogeneous µFEA and provides preliminary evidence that approach reflects broad treatment-related differences in murine vertebral strength. However, larger cohorts and murine-specific material calibration are required before predictive validity can be established.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149149373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pre-clinical evaluation of a smartphone-assisted navigation system for surgical pin positioning in total knee arthroplasty. 智能手机辅助导航系统在全膝关节置换术中定位的临床前评估。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-09 DOI: 10.1088/1873-4030/aeb26c
David Bull, Jiaxin Zhang, Shuqiao Xie, Pierluigi Cuomo, Gareth G Jones, Yuqi Chen, Anthony M J Bull
{"title":"Pre-clinical evaluation of a smartphone-assisted navigation system for surgical pin positioning in total knee arthroplasty.","authors":"David Bull, Jiaxin Zhang, Shuqiao Xie, Pierluigi Cuomo, Gareth G Jones, Yuqi Chen, Anthony M J Bull","doi":"10.1088/1873-4030/aeb26c","DOIUrl":"https://doi.org/10.1088/1873-4030/aeb26c","url":null,"abstract":"<p><p>Total knee arthroplasty (TKA) success is highly dependent on accurate implant alignment, however, 80% of procedures globally are performed manually. Manual procedures have higher alignment errors compared to robotic platforms and patient-specific instrumentation, yet these have limitations of high cost and intraoperative inflexibility, respectively. This study aimed to evaluate the intraoperative pin positioning accuracy and flexibility of a smartphone-assisted navigation system using CT-derived surgical plans. Three participants used the navigation system to perform 108 guide pin insertions (54 femoral, 54 tibial) on surrogate bone models based on CT-derived surgical plans. Testing included both default mechanical axis targets (0°) and user-selected navigated targets ranging from -3° to 3°. Accuracy was assessed by comparing achieved pin trajectories with the preoperative surgical plan. Median absolute angular deviations achieved ranged from 0.9° to 1.6° across all component-plane combinations, with an overall median deviation of 1.3° (IQR 0.6-2.1°). The proportion of insertions within a predefined ±3° clinical accuracy threshold ranged from 83.3% to 100%, and all component-plane combinations demonstrated deviations significantly within this threshold (p < 0.00001). These findings support the technical feasibility of the smartphone-assisted navigation system for surgical pin positioning under controlled pre-clinical conditions. Further studies will evaluate the navigation system in cadaveric models with experienced orthopaedic surgeon participants.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
VVCS: a compact and resource-efficient system for pulsatile-pressure culture of human saphenous veins. VVCS:一个紧凑和资源高效的系统,用于脉动压力培养人类隐静脉。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-08 DOI: 10.1088/1873-4030/aea227
Jianye Zhang, Xiaobo Guo, Tianyu Jia, Shaopeng Dong, Yiping Sun, Lisong Wu, Jubing Zheng, Ran Dong, Kui Zhang
{"title":"VVCS: a compact and resource-efficient system for pulsatile-pressure culture of human saphenous veins.","authors":"Jianye Zhang, Xiaobo Guo, Tianyu Jia, Shaopeng Dong, Yiping Sun, Lisong Wu, Jubing Zheng, Ran Dong, Kui Zhang","doi":"10.1088/1873-4030/aea227","DOIUrl":"10.1088/1873-4030/aea227","url":null,"abstract":"<p><strong>Background: </strong>The great saphenous vein (SV) is widely used for coronary artery bypass grafting (CABG), but vein graft failure remains associated with endothelial injury and intimal hyperplasia. Sophisticated ex vivo platforms can reproduce complex coronary hemodynamics, yet their construction, operating cost, space requirements, and culture throughput may limit routine laboratory use.</p><p><strong>Methods: </strong>We developed a simple and economical<i>in vitro</i>vessel culture system (VVCS) comprising a custom Petri dish, a closed tubing circuit, a peristaltic pump, a pressurized medium bag, and pressure monitoring. Human SV segments from three CABG patients were cultured for 14 d under steady-direction perfusion and pulsatile pressure of 80/120 mmHg at a pump setting of 60-80 RPM. Histology, CD31 immunostaining, and EVG staining were used to assess early remodeling.</p><p><strong>Results: </strong>No contamination was observed during 14 d of culture. Histology demonstrated lumen dilation, medial fiber rearrangement, and focal structural injury. Endothelial coverage decreased in all three samples (Wilcoxon<i>P</i>= 0.25). Mean intimal thickness increased by 1.63-2.35<i>μ</i>m; the donor-level Wilcoxon test yielded<i>P</i>= 0.25, while a repeated-measures linear mixed-effects analysis estimated a mean increase of 2.07<i>μ</i>m (95% CI, 1.75-2.40<i>μ</i>m;<i>P</i>= 5.49 × 10<sup>-5</sup>).</p><p><strong>Conclusion: </strong>The VVCS combines a compact architecture, low medium demand, efficient parallel culture, and sustained pulsatile-pressure conditioning. It provides an accessible model for investigating SV early pressure-associated remodeling after CABG and establishes a foundation for subsequent studies.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148889005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Image-enhanced autonomous navigation in intestinal robotics: a threshold-triggered approach combining dark-area localization and morphological contour guidance short title: enhancing visibility and navigation precision in confined spaces. 肠道机器人图像增强自主导航:一种结合暗区定位和形态轮廓引导的阈值触发方法。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-08 DOI: 10.1088/1873-4030/aeaba4
Shiwei Wang, Junying Yuan, Haoran Deng, Hanyu Deng, Xiuquan Yue, Tianshi Zhang, Shenjin Chen, Haishan Chen
{"title":"Image-enhanced autonomous navigation in intestinal robotics: a threshold-triggered approach combining dark-area localization and morphological contour guidance short title: enhancing visibility and navigation precision in confined spaces.","authors":"Shiwei Wang, Junying Yuan, Haoran Deng, Hanyu Deng, Xiuquan Yue, Tianshi Zhang, Shenjin Chen, Haishan Chen","doi":"10.1088/1873-4030/aeaba4","DOIUrl":"10.1088/1873-4030/aeaba4","url":null,"abstract":"<p><p>Robotic endoscopy offers a potential route to autonomous gastrointestinal navigation. However, autonomous intestinal navigation is hindered by non-rigid lumen deformation and visual degradation from specular reflections, which compromise accurate perception and stable control. We propose a threshold-triggered, vision-driven framework incorporating Navier-Stokes-based highlight suppression. Algorithmically, the system is governed by a threshold-triggered mechanism that acts as a conditional perception gate, dynamically alternating between a lightweight 'dark-area guidance' algorithm for approximately centered navigation and a more detailed 'contour-based guidance' pipeline for corrective steering. The switching policy avoids executing highlight suppression and morphological contour processing in every frame. In phantom-based trials, the system achieved an average speed of 3.10 cm s<sup>-1</sup>on the triangular path. Highlight suppression increased the proportion of frames with normalized center error below 0.1 from 65% to 71%, below 0.2 from 95% to 97%, and below 0.3 from 98% to 100%. The adaptive mechanism decreased runtime by approximately 2% compared to continuous contour processing. Although this absolute reduction was modest, it recovered approximately 89% of the runtime difference between the contour-only and dark-area-only baselines. These phantom-based results support conditional perception allocation while keeping average processing time close to that of lightweight navigation.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149031802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loading effects: geometry versus intrinsic forces in injury risk assessment of the femur in children with osteogenesis imperfecta. 载荷效应:几何与内力在成骨不全儿童股骨损伤风险评估中的作用。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-08 DOI: 10.1088/1873-4030/aea799
Maeve M McDonald, Gerald F Harris, Joseph LeSueur, Peter A Smith, Jessica M Fritz
{"title":"Loading effects: geometry versus intrinsic forces in injury risk assessment of the femur in children with osteogenesis imperfecta.","authors":"Maeve M McDonald, Gerald F Harris, Joseph LeSueur, Peter A Smith, Jessica M Fritz","doi":"10.1088/1873-4030/aea799","DOIUrl":"10.1088/1873-4030/aea799","url":null,"abstract":"<p><p>Osteogenesis imperfecta (OI) is a rare genetic disorder but is the most common disorder of bone etiology with little known about the impact of physiologic factors on fracture risk. Finite element analysis (FE) models of OI bone have been previously developed to examine fracture risk during ambulation and various daily activities of the femur and tibia. This study aims to further investigate the impact of long bone deformity and muscle activation forces in children and adolescents with OI. Pediatric femoral FE models of normal, OI type I, and OI type III bone material properties assessed effects of lateral bowing versus increased gluteus medius and gluteus maximus force production on bone injury risk. Models incorporating increased lateral bowing and muscle forces showed up to 7.56% higher stress levels than the standard model with no bowing and normal muscle forces, with muscle forces having a greater impact than lateral bowing. This study provides quantitative information to help establish methodology for FE analysis to assess femoral fracture risk in individuals with OI.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Federated simplex-constrained network for fine-grained clock drawing test scoring and cognitive pattern representation. 细粒度时钟绘制测试评分与认知模式表示的联邦简单约束网络。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-08 DOI: 10.1088/1873-4030/aeac5e
Dingyi Liu, Lei Yu
{"title":"Federated simplex-constrained network for fine-grained clock drawing test scoring and cognitive pattern representation.","authors":"Dingyi Liu, Lei Yu","doi":"10.1088/1873-4030/aeac5e","DOIUrl":"10.1088/1873-4030/aeac5e","url":null,"abstract":"<p><p>The clock drawing test is a core tool for the early screening of cognitive impairment. Traditional manual methods are time-consuming and prone to significant subjective bias, while most existing automated methods are 'black-box' approaches that directly map images to scores or category labels. Not only do these methods lack interpretability in their decision-making processes, but they also fail to provide information beyond the raw scores. Furthermore, most of these methods employ a centralized training paradigm. However, due to strict privacy regulations that restrict medical data sharing, achieving multi-center collaboration remains difficult, which hinders clinical deployment. Therefore, this paper proposes the federated simplex-constrained network, which enables collaborative training through federated learning without raw data leaving the local clients; simultaneously, by embedding a simplex-constrained module in the model, a module that serves both as a latent-feature transformation layer and as a cognitive-pattern modeling module, it represents individual cognitive patterns of samples as convex combinations of multiple cognitive prototypes, thereby constructing a task-relevant library of cognitive prototypes. This approach simultaneously achieves fine-grained scoring, interpretability of the decision-making process, and cognitive pattern analysis. Performance experiments were conducted on a dataset of 1370 cross-sectional clock-drawing images collected from a single institution, using the Dirichlet partitioning method to simulate multi-federated clients with highly skewed label distributions. The main experimental results show that this model achieved a macro-average accuracy of 0.847 (95% CI: 0.841-0.854) and a macro-average<i>F</i>1 score of 0.470 (95% CI: 0.405-0.536) on the scoring task.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149065682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanical evaluation of 3D-printed above-knee prosthetic sockets using a biofidelic hyperelastic silicone limb surrogate. 使用仿生超弹性硅胶假肢替代物对3d打印膝上假体进行力学评估。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-06 DOI: 10.1088/1873-4030/aeaba3
Pimpet Sratong-On, Onanong Sukjai, Sawanya Suwannawong, Hui Lin Foo, Kaylen Lim, Chuen Kum Lee, Kazuhiko Sasaki
{"title":"Mechanical evaluation of 3D-printed above-knee prosthetic sockets using a biofidelic hyperelastic silicone limb surrogate.","authors":"Pimpet Sratong-On, Onanong Sukjai, Sawanya Suwannawong, Hui Lin Foo, Kaylen Lim, Chuen Kum Lee, Kazuhiko Sasaki","doi":"10.1088/1873-4030/aeaba3","DOIUrl":"10.1088/1873-4030/aeaba3","url":null,"abstract":"<p><p>Rigid limb surrogates transfer full mechanical loads directly to the prosthetic socket during structural testing, causing premature distal failure and underestimating of actual load capacity. In contrast, soft-compliant surrogates buffer applied loads and enables realistic structural deformation. This study investigates: (i) the influence of rigid Plaster of Paris (PoP) versus biofidelic hyperelastic silicone surrogates on the structural load capacity of 3D-printed transfemoral prosthetic sockets; and (ii) orientation-dependent structural deformation and failure behaviors arising from asymmetric transfemoral anatomy. Sockets encapsulated with PoP and silicone surrogates were evaluated under ((ISO 10328:2016) 2016 Prosthetics-Structural testing of lower-limb prostheses-Requirements and test methods (International Organization for Standardization)) static loading (Condition II) at two loading alignments: toe-off and toe-towards-lateral (90° laterally rotated) configurations. Initial testing with 3D-printed bespoke commercial (BC) connectors induced premature distal connector failure; however, under toe-towards-lateral loading, socket/silicone assemblies exhibited a 4.47-fold greater displacement and a 72.46% higher ultimate force than socket/PoP assemblies. Sockets with an enlarged BC connector encapsulated in the silicone surrogate showed distinct force-displacement hysteresis loops under toe-towards-lateral loading, indicating energy dissipation. Crucially, enlarging the BC connector shifted the failure site from interlayer delamination at the distal end under toe-off to trans-layer fracture across the lateral socket wall. Conversely, socket/PoP assemblies consistently failed at the enlarged BC distal connector regardless of loading orientation. Finite element analysis confirmed non-compliant, uniform contact pressure in socket/PoP assemblies, whereas the silicone surrogate produced compliant pressure gradients. Loading orientation significantly affected the structural deformation (<i>p</i>< 0.05) of socket/silicone assemblies: toe-towards-lateral loading induced two-fold greater deformation and an 18.95% higher ultimate force than under toe-off loading due to the thicker lateral silicone resulting from asymmetric limb geometry. These findings demonstrate that a biofidelic hyperelastic surrogate buffers stress and redistributes contact pressure similar to biological soft tissue, establishing a more accurate pre-clinical framework for evaluating 3D-printed prosthetic socket strength.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149031840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability and comparative evaluation of novel multi-segment kinematic foot model incorporating detailed midfoot kinematics during gait: single-examiner study. 在步态中包含详细的足中部运动学的新型多段运动学足模型的可靠性和比较评估:单考官研究。
IF 2.4 4区 医学
Medical Engineering & Physics Pub Date : 2026-10-06 DOI: 10.1088/1873-4030/aea997
Shiki Takeuchi, Masaya Anan
{"title":"Reliability and comparative evaluation of novel multi-segment kinematic foot model incorporating detailed midfoot kinematics during gait: single-examiner study.","authors":"Shiki Takeuchi, Masaya Anan","doi":"10.1088/1873-4030/aea997","DOIUrl":"10.1088/1873-4030/aea997","url":null,"abstract":"<p><p>The accurate assessment of midfoot motion during gait presents a considerable methodological challenge in biomedical measurement and modeling. This study developed and evaluated the intra-session repeatability of the Oita foot model, a novel multi-segment kinematic foot model that incorporates a dedicated midfoot segment defined by three markers on the dorsal cuneiform and cuboid to minimize soft tissue artifacts. Foot kinematics were acquired from 20 young adult participants (20.75 ± 1.34 yr) using a 10-camera three-dimensional motion-capture system. The joint angles of five foot segments were calculated across three planes during the stance phase. The repeatability of the measurements was assessed using the intraclass correlation coefficient (ICC) and coefficient of multiple correlation (CMC). Waveform similarity was compared with the Rizzoli and modified DuPont foot models. Under single-examiner conditions, this model exhibited excellent intra-session repeatability (ICC: 0.928-0.985; CMC: 0.852-0.981) and substantial waveform agreement with the Rizzoli foot model in the sagittal and frontal planes (CMC: 0.920-0.999). Under single-examiner conditions, these findings indicate that the Oita foot model may provide a useful framework for the detailed assessment of foot kinematics during gait. However, its repeatability across different examiners and clinical populations remains to be established.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149002708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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