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Late-onset anxiety related to spontaneous intracranial hypotension in an elderly woman. 一名老年妇女因自发性颅内低血压而迟发焦虑症。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-06-30 DOI: 10.1080/13554794.2024.2368877
Yara Chamoun, Boris Chaumette, Nicolas Mélé, Alexandre Salvador, Marion Plaze, Raphaël Gaillard
{"title":"Late-onset anxiety related to spontaneous intracranial hypotension in an elderly woman.","authors":"Yara Chamoun, Boris Chaumette, Nicolas Mélé, Alexandre Salvador, Marion Plaze, Raphaël Gaillard","doi":"10.1080/13554794.2024.2368877","DOIUrl":"10.1080/13554794.2024.2368877","url":null,"abstract":"","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"114-115"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increased memory confidence and delusions in Alzheimer's disease: a preliminary study. 阿尔茨海默氏症患者记忆信心增强和妄想：一项初步研究。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-11-08 DOI: 10.1080/13554794.2024.2426267
Emma McLachlan, Kathy Liu, Lauren Huzzey, Neil Burgess, Suzanne Reeves, Robert Howard
{"title":"Increased memory confidence and delusions in Alzheimer's disease: a preliminary study.","authors":"Emma McLachlan, Kathy Liu, Lauren Huzzey, Neil Burgess, Suzanne Reeves, Robert Howard","doi":"10.1080/13554794.2024.2426267","DOIUrl":"10.1080/13554794.2024.2426267","url":null,"abstract":"<p><p>There is uncertainty about whether delusion formation in Alzheimer's disease (AD) can be explained by false memories. \"Metamemory,\" the ability to self-evaluate memory and identify memory errors, is impaired in people with delusions in schizophrenia. Our objective was to investigate whether false memory and metamemory were associated with delusions in AD. Participants with mild AD, with and without delusions, completed a computerized word recognition task and a metamemory measure. Group differences were compared using independent-samples t-tests or Mann Whitney tests. Significant findings were explored through binary logistic regression modeling. Participants with delusions (<i>n</i> = 10) gave more high confidence responses, significantly so for correct responses; percentage of high confidence correct responses for those with delusions (mean (SD)) was 69.7% (31.0%) and for those without (<i>n</i> = 14) was 43.5% (29.9%); <i>t</i><sub>22</sub> = -2.09, <i>p</i> = .049. This remained significant when sex was included in regression modeling; for each 1.0% increase in high confidence correct responses, participants were 5.4% more likely to have delusions (Exp(β) 1.054, 95% CI 1.007-1.105, <i>p</i> = .025). Findings provide tentative support for a link between metamemory and delusions in AD. This should be explored in a larger sample as it has potential implications for treatment.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"142-145"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11614042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical considerations regarding suspected "BvFTD-by-proxy": a case series. 关于疑似 "代理乙型脑发育异常综合征 "的临床考虑：一个病例系列。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-10-27 DOI: 10.1080/13554794.2024.2419177
Erin R Weinhold, Christina L Vaughan, Mary O'Hara, Elizabeth M Bloemen, Delia Bakeman, Simon Ducharme, Peter S Pressman
{"title":"Clinical considerations regarding suspected \"BvFTD-by-proxy\": a case series.","authors":"Erin R Weinhold, Christina L Vaughan, Mary O'Hara, Elizabeth M Bloemen, Delia Bakeman, Simon Ducharme, Peter S Pressman","doi":"10.1080/13554794.2024.2419177","DOIUrl":"10.1080/13554794.2024.2419177","url":null,"abstract":"<p><p>A diagnosis of behavioral variant frontotemporal dementia (bvFTD) often relies on informant reports of significant behavioral changes. \"BvFTD-by-proxy\" describes situations of neuropsychiatric changes reported solely by an informant under circumstances that may raise questions regarding their objectivity. We present three cases of bvFTD-like symptoms reported by spouses, where progression was unclear, testing showed mild but stable executive dysfunction, and neuroimaging was unremarkable. The subjective nature of bvFTD criteria leaves patients vulnerable to misleading informant reports, especially amid relational discord, and may threaten patient autonomy. Recognizing and managing this situation is critical but time-consuming, often requiring coordinated care across multiple providers.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"135-141"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socioemotional dysfunction and the greater good: a case study. 社会情感功能障碍与更大的利益：案例研究。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-09-21 DOI: 10.1080/13554794.2024.2404682
Rea Antoniou, Patrick Callahan, Joel H Kramer, Bruce L Miller, Winston Chiong, Katherine P Rankin
{"title":"Socioemotional dysfunction and the greater good: a case study.","authors":"Rea Antoniou, Patrick Callahan, Joel H Kramer, Bruce L Miller, Winston Chiong, Katherine P Rankin","doi":"10.1080/13554794.2024.2404682","DOIUrl":"10.1080/13554794.2024.2404682","url":null,"abstract":"<p><p>Moral cognition has largely been studied via dilemmas in which making a utilitarian choice causes instrumental harm (negative dimension). Studies of utilitarianism link this behavior with socioemotional unresponsiveness. However, there is a positive dimension of utilitarianism in which one sacrifices the good of oneself or close others for the overall welfare. We measured utilitarian choices multidimensionally in a patient with behavioral variant frontotemporal dementia (bvFTD), incorporating dilemmas accounting for negative and positive dimensions. Despite socioemotional deficits our patient was highly utilitarian in the positive, dimension of utilitarianism. This case study challenges the tendency to automatically associate bvFTD with antisocial tendencies.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"125-134"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11604522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The psychiatric profile of Vincent van Gogh: an analysis. 文森特-凡高的精神状况：分析。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-11-21 DOI: 10.1080/13554794.2024.2424190
Kirsten E Abelskov, Mikkel Bogh
{"title":"The psychiatric profile of Vincent van Gogh: an analysis.","authors":"Kirsten E Abelskov, Mikkel Bogh","doi":"10.1080/13554794.2024.2424190","DOIUrl":"10.1080/13554794.2024.2424190","url":null,"abstract":"<p><p>This study explores Vincent van Gogh's struggles with executive functions and his experiences with episodes of depression. In the final years of his life, Van Gogh encountered visual and auditory hallucinations, often lasting for few days. His correspondence reveals his concerns about the clarity of his mind during this period, suggesting the possibility of visual hallucinations influencing his artistic work. He mentioned the term \"delirium\" in his letters, indicating the presence of a brief psychotic episode. This study also considers the potential influence of factors like nutrition, tobacco, alcohol consumption, somatic diseases, and psychological distress on his susceptibility to delirium.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"149-152"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrograde and semantic amnesia in a case of post-treatment Lyme disease syndrome: did something lead to a psychogenic memory loss? A single-case study. 一例治疗后莱姆病综合征患者的逆行性和语义性失忆：是否有什么导致了精神性失忆？单例研究。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-07-04 DOI: 10.1080/13554794.2024.2371906
Alessandra Redolfi, Vera Rota, Clara Tirloni, Riccardo Buraschi, Chiara Arienti, Maurizio Vincenzo Falso
{"title":"Retrograde and semantic amnesia in a case of post-treatment Lyme disease syndrome: did something lead to a psychogenic memory loss? A single-case study.","authors":"Alessandra Redolfi, Vera Rota, Clara Tirloni, Riccardo Buraschi, Chiara Arienti, Maurizio Vincenzo Falso","doi":"10.1080/13554794.2024.2371906","DOIUrl":"10.1080/13554794.2024.2371906","url":null,"abstract":"<p><strong>Objective: </strong>To describe a case of Post-Treatment Lyme Disease Syndrome (PTLDS) with an atypical cognitive profile.</p><p><strong>Method: </strong>A 41-year-old PTLDS patient underwent comprehensive neuropsychological testing and psychological assessment.</p><p><strong>Results: </strong>The patient exhibited impaired intensive attention but preserved selective attention. Executive functions were normal. Short-term and anterograde memory were intact, while retrograde and semantic memory were significantly impaired. The patient also experienced identity loss, specific phobias, dissociative symptoms, and depressed mood.</p><p><strong>Conclusions: </strong>Severe episodic-autobiographical and retrograde semantic amnesia was consistent with some reports of dissociative amnesia. Loss of identity and phobias were also highly suggestive of a psychogenic mechanism underlying amnesia.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"97-105"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"¿Cómo qué, cómo qué? cómo qué?" Single-language echolalia in a bilingual female with progressive supranuclear palsy: a case report. "一名患有进行性核上性麻痹的双语女性的单语回声：病例报告。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-07-22 DOI: 10.1080/13554794.2024.2377206
Lubnaa Abdullah, Esti Blanco Elorietta, David Lee Valdez
{"title":"\"¿Cómo qué, cómo qué? cómo qué?\" Single-language echolalia in a bilingual female with progressive supranuclear palsy: a case report.","authors":"Lubnaa Abdullah, Esti Blanco Elorietta, David Lee Valdez","doi":"10.1080/13554794.2024.2377206","DOIUrl":"10.1080/13554794.2024.2377206","url":null,"abstract":"<p><p>The case study explores bilingualism and neurodegenerative disorders, specifically progressive supranuclear palsy (PSP) with speech and language disorder (PSP-SL). It features a 78-year-old Mexican American woman who exhibits echolalia only in response to Spanish. This selective impairment suggests unevenly affected language control mechanisms despite her proficiency in both languages. Cognitive function is evaluated with neuropsychological tests; she's diagnosed with PSP-SL, depression, and anxiety. Echolalia in response to one language implies complex phonological retrieval mechanisms. Such observations prompt further inquiry into bilingual language control and processing mechanisms. The case supports evidence that bilingualism may attenuate neurodegeneration effects, suggesting better inhibitory control over disinhibited speech through enhanced executive functioning benefits.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"106-113"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe memory decline along with unaffected executive functions under 400 mg/day of cenobamate leading to a collapse in school performance. 在每天服用 400 毫克仙诺巴马特的情况下，记忆力严重下降，执行功能不受影响，导致学习成绩下降。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-06-13 DOI: 10.1080/13554794.2024.2366472
Juri-Alexander Witt, Susanna Moskau-Hartmann, Karmele Olaciregui Dague, Rainer Surges, Christoph Helmstaedter
{"title":"Severe memory decline along with unaffected executive functions under 400 mg/day of cenobamate leading to a collapse in school performance.","authors":"Juri-Alexander Witt, Susanna Moskau-Hartmann, Karmele Olaciregui Dague, Rainer Surges, Christoph Helmstaedter","doi":"10.1080/13554794.2024.2366472","DOIUrl":"10.1080/13554794.2024.2366472","url":null,"abstract":"<p><p>Cenobamate (CNB) is one of the newer antiseizure medications for the treatment of focal-onset seizures. The cognitive profile of CNB is not yet known in detail. Here we present the case of an 18-year-old male high school student with epilepsy who received adjunctive CNB. Under 400 mg/d of CNB in combination with lamotrigine, a neuropsychological reassessment revealed a severe deterioration of the formerly normal episodic memory functions, while executive functions remained unaffected. The de novo memory deficit had already led to a collapse in school performance and he unexpectedly failed to obtain the general qualification for university entrance. Given the beneficial effect of CNB on seizure control, a dose reduction of CNB to 200 mg/d and introduction of valproic acid was performed. This led to a full recovery of objective memory performance. To our knowledge this is the very first report of a dose-dependent, selective and severe decline in episodic memory performance under CNB, potentially impeding academic achievement. The findings call for a cognitive monitoring of CNB which also addresses episodic memory in addition to executive functions. Systematic studies on episodic memory upon CNB treatment would help to appreciate the scope of this apparently reversible adverse effect.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"91-96"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The recovery of sympathetic skin responses with levodopa in a patient with multiple system atrophy-parkinsonian type. 多系统萎缩-帕金森病型患者使用左旋多巴后交感神经皮肤反应的恢复。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-07-29 DOI: 10.1080/13554794.2024.2381855
Halil Onder, Mustafa Yurtdas, Selcuk Comoglu
{"title":"The recovery of sympathetic skin responses with levodopa in a patient with multiple system atrophy-parkinsonian type.","authors":"Halil Onder, Mustafa Yurtdas, Selcuk Comoglu","doi":"10.1080/13554794.2024.2381855","DOIUrl":"10.1080/13554794.2024.2381855","url":null,"abstract":"<p><p>Herein, we report a 62-year-old female patient with Multiple system atrophy (MSA) at whom the sympathetic skin responses (SSRs) were absent at initial investigations. However, the levodopa therapy provided normalization of SSRs and moderately improvement in orthostatic hypotension-related symptoms. Based on this rare illustration, we discuss the possible mechanisms underlying the pathophysiology of autonomic dysfunction in MSA. We remark on the need for future clinical and experimental studies in this field.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"121-123"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive profile in a young woman with Susac syndrome: a case report. 苏萨克综合征年轻女性的认知概况：病例报告。
IF 0.6 4区 医学
Neurocase Pub Date : 2024-08-01 Epub Date: 2024-06-13 DOI: 10.1080/13554794.2024.2366457
Benedetta Basagni, Laura Abbruzzese, Gaia Radicchi, Alessio Damora, Giulia Salti, Gian Michele Malentacchi, Nevia Caputo, Pierluigi Zoccolotti, Cristiano Scarselli, Mauro Mancuso
{"title":"Cognitive profile in a young woman with Susac syndrome: a case report.","authors":"Benedetta Basagni, Laura Abbruzzese, Gaia Radicchi, Alessio Damora, Giulia Salti, Gian Michele Malentacchi, Nevia Caputo, Pierluigi Zoccolotti, Cristiano Scarselli, Mauro Mancuso","doi":"10.1080/13554794.2024.2366457","DOIUrl":"10.1080/13554794.2024.2366457","url":null,"abstract":"<p><p>Susac syndrome is a rare immune-mediated endotheliopathy affecting the microvasculature. It presents three main symptoms: encephalopathy, branch retinal artery occlusions, and hearing loss . Here we present a new case report focusing on the evolution of the cognitive profile. The patient underwent two neuropsychological examinations. The first, one month after the onset of the symptomatology, highlighted a prevalent involvement of verbal executive functions. The second, conducted six months later, revealed a global improvement in most previously deficient areas, although with the persistence of a difficulty in cognitive estimation. . This case illustrates the importance of a comprehensive analysis of patients with Susac syndrome to appreciate the whole range of cognitive deficits and reliably evaluate symptom evolution.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"83-90"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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