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The brain activation of anxiety disorders with emotional stimuli-an fMRI ALE meta-analysis. 情绪刺激对焦虑障碍脑激活的影响及fMRI ALE meta分析。
IF 0.8 4区 医学
Neurocase Pub Date : 2022-10-01 DOI: 10.1080/13554794.2022.2160262
Xia Liu, Guowei Zheng, Xiuzhen Wang, Yongchao Li, Shanling Ji, Yu Zhang, Chaofan Yao, Yinghui Zhang, Bin Hu
{"title":"The brain activation of anxiety disorders with emotional stimuli-an fMRI ALE meta-analysis.","authors":"Xia Liu,&nbsp;Guowei Zheng,&nbsp;Xiuzhen Wang,&nbsp;Yongchao Li,&nbsp;Shanling Ji,&nbsp;Yu Zhang,&nbsp;Chaofan Yao,&nbsp;Yinghui Zhang,&nbsp;Bin Hu","doi":"10.1080/13554794.2022.2160262","DOIUrl":"https://doi.org/10.1080/13554794.2022.2160262","url":null,"abstract":"<p><p>Numerous studies have analyzed the state of brain activation about anxiety disorders under emotional stimuli. However, there is no meta-analysis to assess the commonality and specificity activation concerning different subtypes of anxiety. Here, we used ALE to assess this. 29 studies revealed increased bilateral amygdala, anterior cingulate gyrus, parahippocampal gyrus activation in anxiety disorders during emotional stimuli. Moreover, we observed decreased activations in the posterior cingulate, lingual gyrus, and precuneus. In sub-analysis, although different anxiety showed dissimilar activations, the principal activations were observed in limbic lobe, which might indicate the limbic circuit was the main neural reflection of anxiety symptoms.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 5","pages":"448-457"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9361636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual and social differences in dyslexia: deep phenotyping of four cases with spared phonology. 阅读障碍的视觉和社会差异:4例语音缺失的深层表型。
IF 0.6 4区 医学
Neurocase Pub Date : 2022-10-01 Epub Date: 2022-11-30 DOI: 10.1080/13554794.2022.2145905
Eleanor R Palser, Zachary A Miller, Abigail E Licata, Nicole A Yabut, Swati P Sudarsan, Boon Lead Tee, Jessica A Deleon, Maria Luisa Mandelli, Eduardo Caverzasi, Virginia E Sturm, Robert Hendren, Katherine L Possin, Bruce L Miller, Maria Luisa Gorno Tempini, Christa Watson Pereira
{"title":"Visual and social differences in dyslexia: deep phenotyping of four cases with spared phonology.","authors":"Eleanor R Palser, Zachary A Miller, Abigail E Licata, Nicole A Yabut, Swati P Sudarsan, Boon Lead Tee, Jessica A Deleon, Maria Luisa Mandelli, Eduardo Caverzasi, Virginia E Sturm, Robert Hendren, Katherine L Possin, Bruce L Miller, Maria Luisa Gorno Tempini, Christa Watson Pereira","doi":"10.1080/13554794.2022.2145905","DOIUrl":"10.1080/13554794.2022.2145905","url":null,"abstract":"<p><p>Diagnostic criteria for dyslexia describe specific reading difficulties, and single-deficit models, including the phonological deficit theory, have prevailed. Children seeking diagnosis, however, do not always show phonological deficits, and may present with strengths and challenges beyond reading. Through extensive neurological, neuropsychological, and academic evaluation, we describe four children with visuospatial, socio-emotional, and attention impairments and spared phonology, alongside long-standing reading difficulties. Diffusion tensor imaging revealed white matter alterations in inferior longitudinal, uncinate, and superior longitudinal fasciculi versus neurotypical children. Findings emphasize that difficulties may extend beyond reading in dyslexia and underscore the value of deep phenotyping in learning disabilities.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 5","pages":"419-431"},"PeriodicalIF":0.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10776736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the role of the uncinate fasciculus in proper noun naming: awake brain tumor resections and stereo EEG targeted electrical stimulation multiple case study. 探讨钩扣束在专有名词命名中的作用:清醒脑肿瘤切除和立体脑电图定向电刺激多例研究。
IF 0.8 4区 医学
Neurocase Pub Date : 2022-10-01 DOI: 10.1080/13554794.2022.2160261
Jun Min Koay, Karen E Blackmon, Erik H Middlebrooks, Alfredo Quinones-Hinojosa, Kaisorn L Chaichana, Anteneh M Feyissa, Sanjeet S Grewal, David S Sabsevitz
{"title":"Examining the role of the uncinate fasciculus in proper noun naming: awake brain tumor resections and stereo EEG targeted electrical stimulation multiple case study.","authors":"Jun Min Koay,&nbsp;Karen E Blackmon,&nbsp;Erik H Middlebrooks,&nbsp;Alfredo Quinones-Hinojosa,&nbsp;Kaisorn L Chaichana,&nbsp;Anteneh M Feyissa,&nbsp;Sanjeet S Grewal,&nbsp;David S Sabsevitz","doi":"10.1080/13554794.2022.2160261","DOIUrl":"https://doi.org/10.1080/13554794.2022.2160261","url":null,"abstract":"<p><p>While there is strong evidence from lesion and functional imaging studies implicating the left anterior temporal pole (LTP) in naming unique entities, less is known about white matter tracts in category-specific naming. We present evidence that implicates the uncinate fasciculus (UF) in proper noun naming. First, we describe two patients with left LTP gliomas who developed category specific worsening in proper noun naming in real time during awake surgery when the UF was surgically involved . We then describe a third case involving targeted electrical stimulation of the UF using stereo-electroencephalography (sEEG) that resulted in category specific naming disturbance for proper nouns..</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 5","pages":"439-447"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9361633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Treatment-resistant diabetic chorea manifesting with psychiatric symptoms: a case report. 以精神症状为表现的难治性糖尿病舞蹈病1例
IF 0.8 4区 医学
Neurocase Pub Date : 2022-10-01 DOI: 10.1080/13554794.2022.2145906
Tsubasa Miyauchi, Masami Yoshii, Takeo Oshima, Ken Tomotsune, Kazuhiro Tomiyasu
{"title":"Treatment-resistant diabetic chorea manifesting with psychiatric symptoms: a case report.","authors":"Tsubasa Miyauchi,&nbsp;Masami Yoshii,&nbsp;Takeo Oshima,&nbsp;Ken Tomotsune,&nbsp;Kazuhiro Tomiyasu","doi":"10.1080/13554794.2022.2145906","DOIUrl":"https://doi.org/10.1080/13554794.2022.2145906","url":null,"abstract":"<p><p>We report a case of a 69-year-old man with treatment-resistant diabetic chorea presenting psychiatric symptoms. The right chorea lasted for 3 months and was refractory to control of diabetes mellitus or administration of haloperidol and benzodiazepines. Only administration of tiapride was efficacious. Magnetic resonance spectrometry and dopamine transporter-single photon emission computed tomography suggested that sustained ischemia at the striatum may lead to impaired expression of dopamine transporters, thereby resulting in deterioration in the indirect pathway. Tiapride inhibited dopamine D2 receptors, thereby restoring the function of the indirect pathway and resulting in improvement of diabetic chorea.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 5","pages":"432-438"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10854366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A 1p31.3 deletion encompassing the nuclear factor 1A gene presenting as possible temporal lobe epilepsy in association with schizoaffective disorder. 包含核因子1A基因的1p31.3缺失可能表现为与分裂情感性障碍相关的颞叶癫痫。
IF 0.8 4区 医学
Neurocase Pub Date : 2022-08-01 Epub Date: 2022-10-09 DOI: 10.1080/13554794.2022.2132869
Mark A Colijn, Monica Hrynchak, Chantelle T Hrazdil, Veerle Willaeys, Randall F White, Robert M Stowe
{"title":"A 1p31.3 deletion encompassing the nuclear factor 1A gene presenting as possible temporal lobe epilepsy in association with schizoaffective disorder.","authors":"Mark A Colijn,&nbsp;Monica Hrynchak,&nbsp;Chantelle T Hrazdil,&nbsp;Veerle Willaeys,&nbsp;Randall F White,&nbsp;Robert M Stowe","doi":"10.1080/13554794.2022.2132869","DOIUrl":"https://doi.org/10.1080/13554794.2022.2132869","url":null,"abstract":"<p><p>Chromosome 1p32-p31 deletion syndrome, which is characterized by a variety of neurodevelopmental abnormalities, is thought to occur as a result of nuclear factor 1A (<i>NFIA</i>) haploinsufficiency. We present a case of a right-handed 40-year-old female with a 1p31.3 deletion, who exhibited numerous common features of this syndrome, in addition to treatment resistant schizoaffective disorder and possible temporal lobe epilepsy, making her presentation unique. While neither psychosis nor temporal lobe epilepsy has been described in this syndrome previously, these conditions likely occurred in our patient as a result of <i>NFIA</i> haploinsufficiency.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 4","pages":"382-387"},"PeriodicalIF":0.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33494098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Visuomotor misalignment induced through immersive virtual reality to improve spatial neglect: a case-series study. 沉浸式虚拟现实诱导的视觉运动失调改善空间忽视:案例系列研究。
IF 0.8 4区 医学
Neurocase Pub Date : 2022-08-01 Epub Date: 2022-10-11 DOI: 10.1080/13554794.2022.2134037
Peii Chen, Olga Boukrina, Denise Krch
{"title":"Visuomotor misalignment induced through immersive virtual reality to improve spatial neglect: a case-series study.","authors":"Peii Chen,&nbsp;Olga Boukrina,&nbsp;Denise Krch","doi":"10.1080/13554794.2022.2134037","DOIUrl":"https://doi.org/10.1080/13554794.2022.2134037","url":null,"abstract":"<p><p>One evidence-based treatment for spatial neglect is prism adaptation (PA) treatment. PA after-effects, i.e., the implicit shifts in the arm reaching position toward the neglected side of space after prism removal, are considered fundamental to PA treatment effects. In the present study, the arm reaching position was shifted through a visuomotor misalignment procedure using immersive virtual reality (VR). To examine whether this procedure might have a beneficial impact on spatial neglect, we conducted a multi-baseline experiment in three individuals with chronic left-sided neglect post stroke. Improved spatial neglect was observed in all participants immediately after 5 sessions with two rounds in each. Two participants demonstrated lasting or continuous improvement two weeks later. Participants' pattern of brain lesions did not appear to clearly explain performance differences. The findings suggest that VR-induced visuomotor misalignment may improve spatial neglect immediately after a multi-session treatment course. The optimal number of sessions will be determined by future studies with a larger sample size, which may also elucidate the number of sessions sufficient for sustained improvement in most patients. Further investigations will identify the neural mechanisms underlying VR-induced visuomotor misalignment, which may or may not be identical to PA after-effects.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 4","pages":"393-402"},"PeriodicalIF":0.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33501089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical, radiologic, and pathologic features of the globular glial tauopathy subtype of frontotemporal lobar degeneration in right temporal variant frontotemporal dementia with salient features of Geschwind syndrome. 具有Geschwind综合征显著特征的右颞变异性额颞叶痴呆的额颞叶变性球状神经胶质tau病亚型的临床、放射学和病理特征。
IF 0.8 4区 医学
Neurocase Pub Date : 2022-08-01 Epub Date: 2022-10-17 DOI: 10.1080/13554794.2022.2130805
Sylvia Josephy-Hernandez, Michael Brickhouse, Samantha Champion, David Dongkyung Kim, Alexandra Touroutoglou, Matthew Frosch, Bradford C Dickerson
{"title":"Clinical, radiologic, and pathologic features of the globular glial tauopathy subtype of frontotemporal lobar degeneration in right temporal variant frontotemporal dementia with salient features of Geschwind syndrome.","authors":"Sylvia Josephy-Hernandez,&nbsp;Michael Brickhouse,&nbsp;Samantha Champion,&nbsp;David Dongkyung Kim,&nbsp;Alexandra Touroutoglou,&nbsp;Matthew Frosch,&nbsp;Bradford C Dickerson","doi":"10.1080/13554794.2022.2130805","DOIUrl":"10.1080/13554794.2022.2130805","url":null,"abstract":"<p><p>Globular Glial Tauopathy (GGT) is a rare form of Frontotemporal Lobar Degeneration (FTLD) consisting of 4-repeat tau globular inclusions in astrocytes and oligodendrocytes. We present the pathological findings of GGT in a previously published case of a 73-year-old woman with behavioral symptoms concerning for right temporal variant frontotemporal dementia with initial and salient features of Geschwind syndrome. Clinically, she lacked motor abnormalities otherwise common in previously published GGT cases. Brain MRI showed focal right anterior temporal atrophy (indistinguishable from five FTLD-TDP cases) and subtle ipsilateral white matter signal abnormalities. Brain autopsy showed GGT type III and Alzheimer's neuropathologic changes. .</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 4","pages":"375-381"},"PeriodicalIF":0.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682487/pdf/nihms-1845543.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33517643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A teenager with combined methylmalonic aciduria and homocystinuria (CblC type) presenting with neurological symptoms and congenital heart diseases: a case report. 青少年合并甲基丙二酸尿和同型半胱氨酸尿(CblC型)表现为神经系统症状和先天性心脏病:1例报告。
IF 0.8 4区 医学
Neurocase Pub Date : 2022-08-01 Epub Date: 2022-10-11 DOI: 10.1080/13554794.2022.2132870
Li Zhou, Qin Yang
{"title":"A teenager with combined methylmalonic aciduria and homocystinuria (CblC type) presenting with neurological symptoms and congenital heart diseases: a case report.","authors":"Li Zhou,&nbsp;Qin Yang","doi":"10.1080/13554794.2022.2132870","DOIUrl":"https://doi.org/10.1080/13554794.2022.2132870","url":null,"abstract":"<p><p>Combined methylmalonic acidemia and homocystinuria, is a rare autosomal recessive disorder due to defective intracellular cobalamin metabolism. We report an 18-year-old Chinese male who presented with hypermyotonia, seizures, and congenital heart diseases. Mutation analysis revealed c.365A>T and c.482 G>A mutations in the <i>MMACHC</i> gene, diagnosed with methylmalonic aciduria and homocystinuria (CblC type). After treatment with vitamin B<sub>12</sub>, L-carnitine, betaine, and folate, which resulted in an improvement in his clinical symptoms and laboratory values. This case emphasizes that inborn errors of metabolism should be considered for a teenager presenting with challenging or neurologic symptoms, especially when combined with unexplained heart diseases.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 4","pages":"388-392"},"PeriodicalIF":0.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33499158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Very early-onset behavioral variant frontotemporal dementia in a patient with a variant of uncertain significance of a FUS gene mutation. 非常早发行为变异性额颞叶痴呆患者的变异不确定意义的FUS基因突变。
IF 0.8 4区 医学
Neurocase Pub Date : 2022-08-01 Epub Date: 2022-10-13 DOI: 10.1080/13554794.2022.2135448
Cristiano Schaffer Aguzzoli, Petronilla Battista, Rafi Hadad, Yuri Ferreira Felloni Borges, Lucas Porcello Schilling, Bruce L Miller
{"title":"Very early-onset behavioral variant frontotemporal dementia in a patient with a variant of uncertain significance of a <i>FUS</i> gene mutation.","authors":"Cristiano Schaffer Aguzzoli,&nbsp;Petronilla Battista,&nbsp;Rafi Hadad,&nbsp;Yuri Ferreira Felloni Borges,&nbsp;Lucas Porcello Schilling,&nbsp;Bruce L Miller","doi":"10.1080/13554794.2022.2135448","DOIUrl":"https://doi.org/10.1080/13554794.2022.2135448","url":null,"abstract":"<p><p>The behavioral variant of Frontotemporal dementia (bvFTD) has typically a progressive course with cognitive and behavioral changes that manifests between 50 and 70 years. Very early-onset bvFTD with rapid progression is a rare syndrome under the frontotemporal lobar degeneration (FTLD) umbrella that has been associated with a variety of protein deposition and genetic mutations. We present a case of a 24-year-old man who developed behavioral symptoms and progressed with severe cognitive impairment and functional loss within months.   Genetic testing identified a variant of uncertain significance (VUS) mutation in the <i>FUS</i> gene.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 4","pages":"403-409"},"PeriodicalIF":0.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33529268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pupillometry as an index for cognitive processing in behavioral variant FrontoTemporal Dementia: a series of case studies. 瞳孔测量作为行为变异额颞叶痴呆的认知加工指标:一系列案例研究。
IF 0.8 4区 医学
Neurocase Pub Date : 2022-06-01 DOI: 10.1080/13554794.2022.2094809
Mohamad El Haj, Dimitrios Kapogiannis, Claire Boutoleau-Bretonnière
{"title":"Pupillometry as an index for cognitive processing in behavioral variant FrontoTemporal Dementia: a series of case studies.","authors":"Mohamad El Haj,&nbsp;Dimitrios Kapogiannis,&nbsp;Claire Boutoleau-Bretonnière","doi":"10.1080/13554794.2022.2094809","DOIUrl":"https://doi.org/10.1080/13554794.2022.2094809","url":null,"abstract":"<p><p>We investigated whether pupil size can variate with the intensity of cognitive processing in patients with behavioral-variant-Frontotemporal-Dementia (bvFTD). We invited five bvFTD participants and 21 controls to perform forward spans and backward spans, and, in a control condition, to count aloud. We recorded pupil activity using eye-tracking-glasses during the spans and control condition. Analysis demonstrated larger pupil sizes during backward spans than during forward spans, and larger pupil sizes during forward spans than during counting in both bvFTD and control participants. These findings demonstrate how increased cognitive load triggers increased pupil size and how this connection is maintained in bvFTD.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":"28 3","pages":"270-275"},"PeriodicalIF":0.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474719/pdf/nihms-1827924.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9703317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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