A multimodal imaging approach to foreign accent syndrome. A case report.

IF 0.6 4区医学 Q4 CLINICAL NEUROLOGY

Neurocase Pub Date : 2022-12-01 DOI:10.1080/13554794.2023.2168558

Greta Demichelis, Dunja Duran, Giuseppe Ciullo, Lorenzo Lorusso, Stefano Zago, Sara Palermo, Anna Nigri, Matilde Leonardi, Maria Grazia Bruzzone, Davide Fedeli

引用次数: 0

Abstract

ABSTRACT This article describes a case of Foreign accent syndrome (FAS) in an Italian woman who developed a Canadian-like foreign accent without brain damage (functional FAS). The patient underwent an in-depth neuroimaging and (neuro)psychological evaluation. Language networks in the frontotemporal-parietal areas were typically activated bilaterally through fMRI and MEG assessments based on task-based data. Resting-state fMRI showed preserved connectivity between language areas. An obsessive-compulsive personality profile and mild anxiety were found, suggesting psychological and psychiatric factors may be relevant. Accordingly with our findings, multimodal imaging is beneficial to understand FAS neurological and functional etiologies.

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外国口音综合征的多模态成像方法。一份病例报告。

本文描述了一例外国口音综合征(FAS)，一位意大利妇女在没有脑损伤的情况下发展出了类似加拿大的外国口音(功能性FAS)。患者接受了深入的神经影像学检查和(神经)心理评估。通过基于任务数据的功能磁共振成像和脑磁图评估，前额颞顶叶区域的语言网络通常是双侧激活的。静息状态功能磁共振成像显示语言区域之间保持了连接。他们还发现了强迫性人格特征和轻度焦虑，这表明心理和精神因素可能与此有关。根据我们的发现，多模态成像有助于了解FAS的神经和功能病因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurocase 医学-精神病学

CiteScore

1.40

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.