Comparison of executive function in idiopathic generalized epilepsy versus temporal lobe epilepsy.

IF 0.6 4区医学 Q4 CLINICAL NEUROLOGY

Neurocase Pub Date : 2024-10-01 Epub Date: 2024-11-29 DOI:10.1080/13554794.2024.2436160

Nahid Ashjazadeh, Ali Namjoo-Moghadam, Arash Mani, Neda Doostmohammadi, Mahnaz Bayat, Mohammad Saied Salehi, Elahe Rafiei, Mahtab Rostamihosseinkhani, Alireza Khani-Robati, Etrat Hooshmandi

引用次数: 0

Abstract

Executive function (EF) deficits are common in epilepsy and impact quality of life. This study compares EF in idiopathic generalized epilepsy (IGE) and temporal lobe epilepsy (TLE) patients to healthy controls. Fifty-six IGE patients, 56 TLE patients, and 60 controls (matched by age) completed cognitive tests assessing attention, memory, learning, and verbal fluency. Both epilepsy groups performed worse than controls, with TLE patients showing significantly poorer verbal learning and memory compared to IGE patients. These findings suggest that TLE patients have more severe EF impairments, likely due to focal temporal lobe dysfunction and disruptions in EF networks.

查看原文本刊更多论文

特发性全身性癫痫与颞叶癫痫的执行功能比较。

执行功能（EF）缺陷是常见的癫痫和影响生活质量。本研究将特发性全面性癫痫（IGE）和颞叶癫痫（TLE）患者的EF与健康对照进行比较。56名IGE患者、56名TLE患者和60名对照组（按年龄匹配）完成了认知测试，评估注意力、记忆、学习和语言流畅性。两组癫痫患者的表现都不如对照组，与IGE患者相比，TLE患者的语言学习和记忆能力明显较差。这些发现表明，TLE患者有更严重的EF损伤，可能是由于局灶性颞叶功能障碍和EF网络中断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Neurocase 医学-精神病学

CiteScore

1.40

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.