Neurology Asia最新文献

筛选
英文 中文
Relationship of personality traits with stigmatization, depression, and quality of life in patients with multiple sclerosis 人格特征与多发性硬化症患者的耻辱感、抑郁和生活质量的关系
IF 0.2 4区 医学
Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023mkx
Kubra Yeni, Murat Terzi
{"title":"Relationship of personality traits with stigmatization, depression, and quality of life in patients with multiple sclerosis","authors":"Kubra Yeni, Murat Terzi","doi":"10.54029/2023mkx","DOIUrl":"https://doi.org/10.54029/2023mkx","url":null,"abstract":"Background & Objective: Personality traits are associated with mental health and quality of life in patients with multiple sclerosis (MS). The aim of this study was to determine personality traits in patients with MS and to examine the relationship between these traits and stigmatization, depression and quality of life. Method: This descriptive, cross-sectional study included 80 MS patients and 96 healthy controls. Data were collected online between June and July 2022. Patient/person information form, Eysenck Personality Questionnaire Revised-Short Form (EPQ-RS), Neuro Quality of Life-Stigma Scale, Beck Depression Inventory and MS Quality of Life Scale-54 were used for data collection. Results: When the age variable was controlled, it was found that the mean neuroticism subscale score was higher (p=0.003) and the mean extraversion subscale score was lower (p=0.018) than the control group. In addition, the mean extraversion score was found to be negatively correlated with stigmatization (p<0.05) and depression (p<0.01), and positively correlated with the physical sub-dimension of quality of life (p<0.01). Neuroticism and psychoticism sub-dimensions were positively correlated with stigmatization and depression and negatively correlated with all sub-dimensions of quality of life (p<0.01). In addition, regression analysis showed that depression significantly contributed to the physical health dimension of quality of life and neuroticism personality trait significantly contributed to the mental health dimension. Conclusions: Neurotic personality traits were found to be more dominant in patients with MS. Moreover, all sub-dimensions of personality traits were associated with stigmatization, depression and quality of life. Therefore, personality traits should be considered in interventions to improve mental health and quality of life.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"82 1-2","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139195157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can eGFR be a prognostic factor for endovascular therapy for acute ischemic stroke? eGFR 能否作为急性缺血性脑卒中血管内治疗的预后因素?
IF 0.2 4区 医学
Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023ryi
Zafer Ercan, Sena Boncuk Ulaş, B. Acar, T. Acar, H. Dheir, Yeşim Güzey Aras, Mahmudul Islam, Alper Eryilmaz, Şule Dalkiliç, Ayşe POLAT ZAFER, Nimet UÇAROĞLU CAN
{"title":"Can eGFR be a prognostic factor for endovascular therapy for acute ischemic stroke?","authors":"Zafer Ercan, Sena Boncuk Ulaş, B. Acar, T. Acar, H. Dheir, Yeşim Güzey Aras, Mahmudul Islam, Alper Eryilmaz, Şule Dalkiliç, Ayşe POLAT ZAFER, Nimet UÇAROĞLU CAN","doi":"10.54029/2023ryi","DOIUrl":"https://doi.org/10.54029/2023ryi","url":null,"abstract":"Background & Objective: Chronic kidney disease (CKD) is associated with increased mortality risk in acute stroke patients. This study aims to investigate potential association between CKD and the prognosis of endovascular treated acute ischemic stroke patients. Methods: Patients with endovascular treatment (EVT) for acute ischemic stroke were studied retrospectively in a comprehensive stroke center. Patients were classified as pre-procedural CKD and non-CKD. The groups were compared regarding demographic data, procedural data, and outcomes. Results: A total of 140 patients (69 male, 49.3%) with a mean age of 66.51±11.8 were involved in the study. Symptomatic intracranial hemorrhage in the first 24 hours and mortality in three months were increased in the CKD group (50% vs. 19.8; p=0.001). Excellent and good outcomes were decreased in the CKD group (25% vs. 53.4; p=0.01 and 41.6% vs. 56.9%; p=0.03). Multiple logistic regression adjusted for potential confounders demonstrated that CKD was associated with lower rates of excellent outcome (odds ratio [OR] = 0.50, 95% confidence interval [CI], 0.25 to 0.80, p = 0.01), higher mRS scores (common OR = 1.82, 95% CI, 1.2 to 2.9, p = 0.01), and increased mortality (OR = 2.1, 95% CI, 1.2 to 4.2, p = 0.01) and sICH (OR = 1.15, 95% CI, 1.03 to 3.4, P = 0.04) Conclusion: There is an association between CKD and poorer results in patients with acute ischemic stroke treated with EVT. The presence of CKD should not prohibit patients from undergoing EVT, but taking baseline eGFR into account may improve estimation of prognosis and help decision-making in treatment modality.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"57 26","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139196376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical characteristic and prognosis of amyotrophic lateral sclerosis in a cohort of Thai patients 泰国一组肌萎缩性脊髓侧索硬化症患者的临床特征和预后
IF 0.2 4区 医学
Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023yjk
Narupat Suanprasert, Narumon Tiawijit, Walaiphan Watcharachinnawong, Metha Apiwattanakul, Thanes Termglinjan, Saharat Aungsumart, Chaichana Sinthuwong, Arada Rojana-udomsart
{"title":"Clinical characteristic and prognosis of amyotrophic lateral sclerosis in a cohort of Thai patients","authors":"Narupat Suanprasert, Narumon Tiawijit, Walaiphan Watcharachinnawong, Metha Apiwattanakul, Thanes Termglinjan, Saharat Aungsumart, Chaichana Sinthuwong, Arada Rojana-udomsart","doi":"10.54029/2023yjk","DOIUrl":"https://doi.org/10.54029/2023yjk","url":null,"abstract":"Background & Objective: Clinical course and prognosis in amyotrophic lateral sclerosis (ALS) patients were highly variable. The information in the Thai population is still lacking. This study aimed to determine the clinical association with disease progression and prognostic factors in ALS in Thailand. Methods: This prospective cohort study evaluated 62 patients who has a diagnosis of ALS and followed up at Neurological Institute of Thailand between January 2014 and December 2018. These patients were classified into an alive group and a deceased group. The demographics, clinical characteristics, disease-related severity, and prognosis were analyzed. Results: Of the included patients, there were 40 male and 22 female, the median age at onset was 53.2 years. The median diagnosis time was 13.1 months and median follow-up duration was 18.5 months; 72.6% of patients presented with spinal onset ALS, and 27.4% with bulbar-onset. There were 20 deaths during follow-up, and the median survival time in the deceased cases was 14 months. Worse prognosis factors were bulbar symptoms at onset and low amyotrophic lateral sclerosis functional rating scale (ALSFRS) at diagnosis. Conclusion: The factors associated with lower survival in ALS patients were bulbar symptoms at onset and low ALSFRS at diagnosis.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"34 3","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139187770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma S100A1 protein: An effective prognostic biomarker for 3-month clinical outcome in acute ischemic stroke patients 血浆 S100A1 蛋白:急性缺血性脑卒中患者 3 个月临床预后的有效生物标志物
IF 0.2 4区 医学
Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023ijm
Guo Hong, Haina Zhao, Yuxuan Yin, Zhaohao Zeng, Yu Luo, Lili Zhang
{"title":"Plasma S100A1 protein: An effective prognostic biomarker for 3-month clinical outcome in acute ischemic stroke patients","authors":"Guo Hong, Haina Zhao, Yuxuan Yin, Zhaohao Zeng, Yu Luo, Lili Zhang","doi":"10.54029/2023ijm","DOIUrl":"https://doi.org/10.54029/2023ijm","url":null,"abstract":"Background: Plasma S100A1 protein is a novel inflammation biomarker associated with acute myocardial infarction and neurodegenerative diseases. This study aimed to investigate the predictive value of S100A1 protein for the three-month prognosis of acute ischemic stroke (AIS) patients and the potential pathophysiological mechanisms of AIS. Methods: A total of 206 people in a stroke center from April 2020 to February 2021 were studied. Clinically relevant data and blood indicators were recorded. The clinical outcome was disability or death at discharge or 90 days (defined as a modified Rankin Scale score of 3-6). The relationship between S100A1 protein, NF-κB p65, and IL-6 and functional outcomes was investigated by binary logistic regression analysis and further assessed by the receiver operating characteristic curve (ROC). The correlation between S100A1, NF-κB p65, and IL-6 was detected by Pearson or Spearman correlation analysis. Results: A total of 206 subjects were enrolled (Age, 67.17±10.74; 40.3% female). Patients with unfavorable outcome showed higher S100A1, NF-κB p65, and IL-6 than those with favorable outcome (S100A1, [252.72±25.15]vs[219.84±23.24], P<0.001; NF-κB p65, [4.45±0.71]vs[3.58±0.66], P<0.001; IL-6, [13.86±1.41]vs[12.18±1.73], P<0.001). In multivariate and ROC curve analysis, higher S100A1 (>227.155) (Area under the curve [AUC], 0.864; odds ratio [OR], 1.093; 95% confidence interval [CI], 1.052- 1.135; P <0.001) and higher NF-κB p65 (>3.685) (AUC, 0.807; OR, 6.416; 95% CI, 1.852- 22.229; P=0.003), higher IL-6 (>12.330) (AUC, 0.767; OR, 2.029; 95% CI, 1.136- 3.624; P=0.017) were independently associated with unfavorable outcome. The combined predictive value of the three indexes was higher than that of a single index. There was a significant statistical correlation between S100A1, NF-κB P65 and IL-6(P<0.001). Conclusion: Higher S100A1 protein may be an independent risk factor for predicting the three-month poor prognosis in AIS patients. This protein may mediate inflammatory response through the NF-κB pathway during the pathogenesis of AIS.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"102 ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139195652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for peri-procedural stroke or death in internal carotid artery stenting: A neurology team experience 颈内动脉支架置入术后中风或死亡的风险因素:神经内科团队的经验
IF 0.2 4区 医学
Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023rhu
Ümit Görgülü, Recep Donmez, Berna Arlı, Gurdal Orhan
{"title":"Risk factors for peri-procedural stroke or death in internal carotid artery stenting: A neurology team experience","authors":"Ümit Görgülü, Recep Donmez, Berna Arlı, Gurdal Orhan","doi":"10.54029/2023rhu","DOIUrl":"https://doi.org/10.54029/2023rhu","url":null,"abstract":"Background and Objectives: Suitable cases of extracranial internal carotid artery (ICA) stenosis can be treated with carotid artery stenting (CAS) or carotid endarterectomy. However, major complications in the peri-procedural period, like stroke and death, are more common with CAS. We therefore investigated the risk factors for stroke and death during the peri-procedural period following CAS. Methods: In this study, the files of patients who were treated with CAS by a neurology team during 2020–2022 were retrospectively analyzed. Patient age, gender, vascular risk factors, use of antiplatelet therapy, type of carotid artery stenosis (symptomatic or asymptomatic), measured stenosis degrees, contralateral carotid stenosis, types of aortic arch, balloon angioplasty, use of a filter-type embolism protection device, stent cell design (open or closed), and peri-procedural death, stroke, or myocardial infarction (MI) were recorded. All patients were followed up for the first 30 days after CAS. Results: The mean age of 219 patients included in our study was 67.8 ± 8.38 years and 68.5% were male. The most common comorbid diseases in the patients were hypertension (76.7%), hyperlipidemia (53.4%) and diabetes mellitus (DM) (43.4%). Stroke or death occurred in the peri-procedural period in 15 (6.85%) of the patients, but MI did not occur. No statistically significant difference was observed in terms of age or gender when comparing with the cases without stroke or death. Of the patients suffering stroke or death, ischemic stroke developed in 13 (86.67%), cerebral hemorrhage in two (13.33%) and two patients (13.33%) died. Two-thirds of the strokes were either minor (n=7, 46.67%) or moderate (n=4, 26.67%); 13 (86.67%) were ipsilateral, and 14 (93.33%) were in the anterior circulation. The complication risk was found to be significantly higher in patients with prior stroke (OR=3.865; 95% CI 1.282 to 11.652 p=.016), DM (OR=3.634; 95% CI 1.102 to 11.992 p=.034) and pre-dilation angioplasty (OR=13.100; 95% CI 1.762 to 97.422 p=.012). Conclusion: Prior stroke, DM and pre-dilation angioplasty increase peri-procedural stroke and death in CAS. However, even if a stroke complication develops after CAS, it is often not severe.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":" 70","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139196040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construction and validation of a nomogram model to predict symptomatic intracranial hemorrhage after intravenous thrombolysis in elderly population with severe white matter lesions 构建并验证预测严重白质病变老年人静脉溶栓后无症状颅内出血的提名图模型
IF 0.2 4区 医学
Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023icn
Qiurui Nie, Yu Shen, Zhisheng Deng, Wenwen Xiang, Shenjian Chen, Guangmin Li
{"title":"Construction and validation of a nomogram model to predict symptomatic intracranial hemorrhage after intravenous thrombolysis in elderly population with severe white matter lesions","authors":"Qiurui Nie, Yu Shen, Zhisheng Deng, Wenwen Xiang, Shenjian Chen, Guangmin Li","doi":"10.54029/2023icn","DOIUrl":"https://doi.org/10.54029/2023icn","url":null,"abstract":"Background and Objective: Elderly people are at high prevalence of atherosclerotic cerebral infarction. Cerebral white matter lesions (WMLs) increase the risk of bleeding after intravenous thrombolysis (IVT) although they may also require the IVT. The aim of this study is to develop a clinical nomogram model for post-IVT symptomatic intracranial hemorrhage (sICH), with the aim to prevent sICH in elderly patients with severe WMLs when IVT is being considered. Methods: This is a large single-center retrospective analysis study of elderly patients with severe WMLs receiving IVT from January 2018 to December 2022. Univariate and multi-factor logistic regression analysis were used to construct nomogram model, and a series of validations were performed on the model. Results: More than 2,000 patients with IVT were screened for inclusion in this study after cranial magnetic resonance imaging evaluation. Out of these, 163 elderly patients had cerebral WMLs, and 25 had sICH. In univariate analysis, history of hypertension (p=0.037), hyperlipidemia (p<0.001), NIHSS score before IVT (p<0.001), low-density lipoprotein levels (p=0.016), cholesterol levels (p=0.020), platelet count (p=0.006), systolic blood pressure (p<0.001), diastolic blood pressure (p<0.001) were significantly associated with sICH. In a multifactorial analysis, the NIHSS score before IVT (OR 42.056 CI 7.308-242.012, p<0.001), and diastolic blood pressure (OR 1.050 CI 1.002-1.100, p=0.040) were found to be significantly associated with sICH after IVT. The four most significant risk factors from logistic regression are subsequently fitted to create a predictive model. The accuracy was verified using calibration curves, decision curves, and clinical impact curves, and the model was considered to have strong stability. Conclusions: The NHISS score before IVT and diastolic blood pressure are independent risk factors for sICH after IVT in elderly patients with severe WMLs. The models are highly accurate and can be applied clinically to provide a reliable predictive basis for IVT in elderly patients with severe WMLs.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":" 30","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139196145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modifiable risk factors for dementia in Indonesia: Results from STRiDE project 印度尼西亚痴呆症的可改变风险因素:STRiDE 项目的结果
IF 0.2 4区 医学
Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023nxi
F. Fitri, Nicolas Farina, Y. Turana, I. Theresia, T. P. Sani, Ika Suswanti, Sube Banerjee
{"title":"Modifiable risk factors for dementia in Indonesia: Results from STRiDE project","authors":"F. Fitri, Nicolas Farina, Y. Turana, I. Theresia, T. P. Sani, Ika Suswanti, Sube Banerjee","doi":"10.54029/2023nxi","DOIUrl":"https://doi.org/10.54029/2023nxi","url":null,"abstract":"Background & Objective: Indonesia’s ageing population and increasing number of people living with dementia poses significant challenge to the health system. Better understanding of factors related to dementia prevalence is needed to mitigate risk, improve care, and ultimately reduce the incidence of dementia. In this study, we aimed to describe associations between potential risk factors and dementia in Indonesia. Methods: A cross-sectional study, part of the Strengthening Responses to Dementia in Developing Countries (STRiDE) project, was conducted in two provinces in Indonesia, Jakarta and North Sumatra between September and December 2021. A total of 2,110 older adults and their informants completed questionnaires covering cognitive and functional status, socioeconomic, medical and lifestyle factors. Models for each potential modifiable risk factor were created and then adjusted by age, sex and literacy. Prevalence ratios (PRs) were calculated for each risk factor. Results: In the adjusted models, lower education, lower occupational attainment, unmanaged diabetes, stroke, head trauma within the past 5 years, hearing loss, and chronic obstructive airway disease were all associated with higher prevalence of dementia in Indonesia. Current smoking, historic depression and high blood pressure were associated with higher dementia prevalence, but not statistically significant. Conclusion: Improving socioeconomic status (i.e., education and employment) and reducing health- related risk factors may be viable solutions to reduce the high prevalence rates of dementia in Indonesia. Further longitudinal research is needed to confirm direction of effect and causality.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"21 2","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139196363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the functional status of the “unaffected” hand in hemiplegic patients 评估偏瘫患者“未受影响”手的功能状态
4区 医学
Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023imv
Elzem Bolkan Günaydın, Mustafa Çağrı Öcalan, Aslıhan Uzunkulaoğlu, Saime Ay
{"title":"Evaluation of the functional status of the “unaffected” hand in hemiplegic patients","authors":"Elzem Bolkan Günaydın, Mustafa Çağrı Öcalan, Aslıhan Uzunkulaoğlu, Saime Ay","doi":"10.54029/2023imv","DOIUrl":"https://doi.org/10.54029/2023imv","url":null,"abstract":"Objectives: To evaluate the functional status of the unaffected hand in hemiplegic patients and its relationships with activities of daily living. Methods: This cross-sectional study included 30 right, 30 left hemiplegic patients with ischemic cerebrovascular accident history in last year, and 30 healthy volunteers. All participants were right-hand dominant. Data on age, gender, height, weight, comorbidities, duration of stroke, Brunnstrom recovery stages were recorded. Handgrip strength (with Jamar-type dynamometer), pinch strengths (with pinch-meter), and hand dexterity [with Nine Hole Peg Test (NHPT)] were evaluated in unaffected hand in patient groups and in both hands in control group. Lawton Instrumental Activities of Daily Living Scale (Lawton-IADL) and Functional Independence Measure (FIM) were applied to patient groups. Results: Hand grip and pinch strengths were lower, NHPT duration was longer in right (p=0.004, p=0.03, p<0.001) and left (p=0.03, p=0.02, p=0.002) hemiplegia groups compared to control group. Hand grip and pinch strengths were positively, NHPT duration was negatively correlated with FIM self-care performance (r:0.47 p<0.00, r:0.38 p=0.003, r:-0.40 p=0.002), and Lawton-IADL scores (r:0.48 p<0.001, r:0.42 p=0.001, r:-0.56 p<0.001). Conclusion: Ipsilesional hand, which is considered unaffected, functions are impaired in hemiplegic patients. This functional impairment is associated with greater dependence on activities of daily living.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimating a two-year recurrence risk of ischemic stroke based on Essen Stroke Risk Score and retinal characteristics 基于Essen卒中风险评分和视网膜特征估计缺血性卒中两年复发风险
4区 医学
Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023fxt
Yuanyuan Zhuo, Min Pi, Xingxian Huang, Limin Liu, Zhuoxin Yang
{"title":"Estimating a two-year recurrence risk of ischemic stroke based on Essen Stroke Risk Score and retinal characteristics","authors":"Yuanyuan Zhuo, Min Pi, Xingxian Huang, Limin Liu, Zhuoxin Yang","doi":"10.54029/2023fxt","DOIUrl":"https://doi.org/10.54029/2023fxt","url":null,"abstract":"Objectives: Prediction of recurrence risk after initial ischemic stroke helps improve patient outcomes. We estimated the validity of combining the Essen Stroke Risk Score (ESRS) with retinal characteristics to predict the two-year recurrent risk of ischemic stroke. Methods: A prospective cohort study was conducted at Shenzhen Traditional Chinese Medicine Hospital. Patients with initial ischemic stroke were recruited. ESRS was measured, and fundus photographs were taken by trained physicians. All patients were followed up for 2 years to determine the outcome of recurrent stroke. Logistic models were built using ESRS alone and combined with ESRS and retinal characteristics. The prognostic value of recurrence risk was evaluated by calculating the area under the receiver operating characteristic curve. Results: The total recurrence rate of ischemic events within 2 years was 20%. The risk of recurrence was significantly higher in patients with an ESRS score of &gt;2. Regarding retinal characteristics, patients with recurrent stroke had a lower mean asymmetry index of venules (0.76 vs. 0.77, P=0.00) and bifurcation coefficient of venules (1.29 vs. 1.28, P=0.03) but a higher mean occlusion of arterioles (0.11 vs. 0.13, P=0.01). The area under the curve was 0.5985 based on the logistic regression model with ESRS alone to 0.7294 for the model with both ESRS and retinal characteristics. This study was registered in the Chinese Clinical Trial Registry (registration no. ChiCTR1800019648). Conclusion: A model combining ESRS with retinal characteristics can accurately predict the risk of recurrent stroke.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of repetitive transcranial magnetic stimulation and 2D ultrasound in resection of low-grade glioma at motor strip area in resource limited setting 重复经颅磁刺激和二维超声在资源有限的情况下切除运动带区低级别胶质瘤的应用
4区 医学
Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023wrw
Sushanta Sahoo, Sujita Kar, Chhitij Srivastava
{"title":"Use of repetitive transcranial magnetic stimulation and 2D ultrasound in resection of low-grade glioma at motor strip area in resource limited setting","authors":"Sushanta Sahoo, Sujita Kar, Chhitij Srivastava","doi":"10.54029/2023wrw","DOIUrl":"https://doi.org/10.54029/2023wrw","url":null,"abstract":"Eloquent area glioma surgery is technically demanding. Identification and preservation of the functional area determines the long term outcome. Here we discuss the use of transcranial magnetic stimulation (TMS) and 2D ultrasound (2DUSG) in resection of low grade glioma (LGG) located at motor strip area. In five patients where the LGG was located close to motor area were evaluated with TMS in the preoperative period and the functional area is marked. This information is used for planning the craniotomy. A 2DUSG is used to detect the margin of resection. Complete excision was feasible in two and partial resection in three without any added deficit. TMS is an useful tool for localizing motor area in the pre operative period for patients with tumor located close to the motor area. Additionally 2DUSG provides real time imaging to safeguard the eloquent brain area. Combination of these two offers low cost, easily available method for resecting eloquent area brain tumors in resource limited areas.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135638087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信