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Forthcoming Articles. 即将出版的文章。
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-04-01 Epub Date: 2025-03-18 DOI: 10.1177/10738584251327443
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引用次数: 0
The mind-machine connection: adaptive information processing and new technologies promoting mental health in older adults. 脑机连接:适应性信息处理和促进老年人心理健康的新技术。
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-02-19 DOI: 10.1177/10738584251318948
S S Magalhães, A M Lucas-Ochoa, A M Gonzalez-Cuello, E Fernández-Villalba, M B Pereira Toralles, M T Herrero
{"title":"The mind-machine connection: adaptive information processing and new technologies promoting mental health in older adults.","authors":"S S Magalhães, A M Lucas-Ochoa, A M Gonzalez-Cuello, E Fernández-Villalba, M B Pereira Toralles, M T Herrero","doi":"10.1177/10738584251318948","DOIUrl":"https://doi.org/10.1177/10738584251318948","url":null,"abstract":"<p><p>The human brain demonstrates an exceptional adaptability, which encompasses the ability to regulate emotions, exhibit cognitive flexibility, and generate behavioral responses, all supported by neuroplasticity. Brain-computer interfaces (BCIs) employ adaptive algorithms and machine learning techniques to adapt to variations in the user's brain activity, allowing for customized interactions with external devices. Older adults may experience cognitive decline, which could affect the ability to learn and adapt to new technologies such as BCIs, but both (human brain and BCI) demonstrate adaptability in their responses. The human brain is skilled at quickly switching between tasks and regulating emotions, while BCIs can modify signal-processing algorithms to accommodate changes in brain activity. Furthermore, the human brain and BCI participate in knowledge acquisition; the first one strengthens cognitive abilities through exposure to new experiences, and the second one improves performance through ongoing adjustment and improvement. Current research seeks to incorporate emotional states into BCI systems to improve the user experience, despite the exceptional emotional regulation abilities of the human brain. The implementation of BCIs for older adults could be more effective, inclusive, and beneficial in improving their quality of life. This review aims to improve the understanding of brain-machine interfaces and their implications for mental health in older adults.</p>","PeriodicalId":49753,"journal":{"name":"Neuroscientist","volume":" ","pages":"10738584251318948"},"PeriodicalIF":3.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The conceptual and practical organization of mental illness. 精神疾病的概念和实践组织。
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-02-01 DOI: 10.1177/10738584241311109
{"title":"The conceptual and practical organization of mental illness.","authors":"","doi":"10.1177/10738584241311109","DOIUrl":"https://doi.org/10.1177/10738584241311109","url":null,"abstract":"","PeriodicalId":49753,"journal":{"name":"Neuroscientist","volume":"31 1","pages":"7"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forthcoming Articles. 即将出版的文章。
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-02-01 DOI: 10.1177/10738584241309778
{"title":"Forthcoming Articles.","authors":"","doi":"10.1177/10738584241309778","DOIUrl":"https://doi.org/10.1177/10738584241309778","url":null,"abstract":"","PeriodicalId":49753,"journal":{"name":"Neuroscientist","volume":"31 1","pages":"4"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Importance of Cajal's and Lorente de Nó's Neuroscience to the Birth of Cybernetics. 卡哈尔和洛伦特·德Nó的神经科学对控制论诞生的重要性。
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-02-01 Epub Date: 2023-07-05 DOI: 10.1177/10738584231179932
Juan Manuel Espinosa-Sanchez, Alex Gomez-Marin, Fernando de Castro
{"title":"The Importance of Cajal's and Lorente de Nó's Neuroscience to the Birth of Cybernetics.","authors":"Juan Manuel Espinosa-Sanchez, Alex Gomez-Marin, Fernando de Castro","doi":"10.1177/10738584231179932","DOIUrl":"10.1177/10738584231179932","url":null,"abstract":"<p><p>The beginnings of cybernetics were marked by the publication of two papers in 1943. In the first one, Rosenblueth, Wiener, and Bigelow claimed that purposeful behavior is a circular process controlled by negative feedback. In the second seminal paper, McCulloch and Pitts proposed that neurons are interconnected working as logical operators. Both articles raised human-machine analogies and mathematically formulated cognitive mechanisms. These ideas ignited the interest of von Neumann, who was developing the first stored-program computer. Thus, after a preliminary meeting in 1945, a series of meetings were held between 1946 and 1953. The role of the Spanish neurophysiologist Rafael Lorente de Nó in the beginnings of cybernetics is attested not only by his participation in the core members of these Macy conferences but also for his previous description of reverberating circuits formed by a closed chain of internuncial neurons. This was the first neurobiologic demonstration of a feedback loop. Most researchers considered the central nervous system as a mere reflex organ until then; nevertheless, he demonstrated a self-sustained central activity in the nervous system, supporting the idea of self-regulating mechanisms as a key concept not just in machines but also in the brain.</p>","PeriodicalId":49753,"journal":{"name":"Neuroscientist","volume":" ","pages":"14-30"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9742356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Biomarkers of FTD-ALS. FTD-ALS的新生物标志物。
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-02-01 DOI: 10.1177/10738584241308752
{"title":"Novel Biomarkers of FTD-ALS.","authors":"","doi":"10.1177/10738584241308752","DOIUrl":"https://doi.org/10.1177/10738584241308752","url":null,"abstract":"","PeriodicalId":49753,"journal":{"name":"Neuroscientist","volume":"31 1","pages":"6"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Excitation-Inhibition Balance, Neural Criticality, and Activities in Neuronal Circuits. 神经元回路中的兴奋抑制平衡、神经临界和活动。
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-02-01 Epub Date: 2024-01-31 DOI: 10.1177/10738584231221766
Junhao Liang, Zhuda Yang, Changsong Zhou
{"title":"Excitation-Inhibition Balance, Neural Criticality, and Activities in Neuronal Circuits.","authors":"Junhao Liang, Zhuda Yang, Changsong Zhou","doi":"10.1177/10738584231221766","DOIUrl":"10.1177/10738584231221766","url":null,"abstract":"<p><p>Neural activities in local circuits exhibit complex and multilevel dynamic features. Individual neurons spike irregularly, which is believed to originate from receiving balanced amounts of excitatory and inhibitory inputs, known as the <i>excitation-inhibition balance</i>. The spatial-temporal cascades of clustered neuronal spikes occur in variable sizes and durations, manifested as neural avalanches with scale-free features. These may be explained by the neural criticality hypothesis, which posits that neural systems operate around the transition between distinct dynamic states. Here, we summarize the experimental evidence for and the underlying theory of excitation-inhibition balance and neural criticality. Furthermore, we review recent studies of excitatory-inhibitory networks with synaptic kinetics as a simple solution to reconcile these two apparently distinct theories in a single circuit model. This provides a more unified understanding of multilevel neural activities in local circuits, from spontaneous to stimulus-response dynamics.</p>","PeriodicalId":49753,"journal":{"name":"Neuroscientist","volume":" ","pages":"31-46"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139643231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transfer of Tactile Learning to Untrained Body Parts: Emerging Cortical Mechanisms. 将触觉学习转移到未经训练的身体部位:新出现的皮层机制
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-02-01 Epub Date: 2024-05-30 DOI: 10.1177/10738584241256277
Sebastian M Frank
{"title":"Transfer of Tactile Learning to Untrained Body Parts: Emerging Cortical Mechanisms.","authors":"Sebastian M Frank","doi":"10.1177/10738584241256277","DOIUrl":"10.1177/10738584241256277","url":null,"abstract":"<p><p>Pioneering investigations in the mid-19th century revealed that the perception of tactile cues presented to the surface of the skin improves with training, which is referred to as <i>tactile learning</i>. Surprisingly, tactile learning also occurs for body parts and skin locations that are not physically involved in the training. For example, after training of a finger, tactile learning transfers to adjacent untrained fingers. This suggests that the transfer of tactile learning follows a somatotopic pattern and involves brain regions such as the primary somatosensory cortex (S1), in which the trained and untrained body parts and skin locations are represented close to each other. However, other results showed that transfer occurs between body parts that are not represented close to each other in S1-for example, between the hand and the foot. These and similar findings have led to the suggestion of additional cortical mechanisms to explain the transfer of tactile learning. Here, different mechanisms are reviewed, and the extent to which they can explain the transfer of tactile learning is discussed. What all of these mechanisms have in common is that they assume a representational or functional relationship between the trained and untrained body parts and skin locations. However, none of these mechanisms alone can explain the complex pattern of transfer results, and it is likely that different mechanisms interact to enable transfer, perhaps in concert with higher somatosensory and decision-making areas.</p>","PeriodicalId":49753,"journal":{"name":"Neuroscientist","volume":" ","pages":"98-114"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11809113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic Fatigue Syndrome: Pulling Back the Curtains. 慢性疲劳综合症:拉开窗帘。
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-02-01 DOI: 10.1177/10738584241308723
{"title":"Chronic Fatigue Syndrome: Pulling Back the Curtains.","authors":"","doi":"10.1177/10738584241308723","DOIUrl":"https://doi.org/10.1177/10738584241308723","url":null,"abstract":"","PeriodicalId":49753,"journal":{"name":"Neuroscientist","volume":"31 1","pages":"5"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adenosine and Cortical Plasticity. 腺苷与皮质可塑性
IF 3.5 3区 医学
Neuroscientist Pub Date : 2025-02-01 Epub Date: 2024-03-18 DOI: 10.1177/10738584241236773
Irene Martínez-Gallego, Antonio Rodríguez-Moreno
{"title":"Adenosine and Cortical Plasticity.","authors":"Irene Martínez-Gallego, Antonio Rodríguez-Moreno","doi":"10.1177/10738584241236773","DOIUrl":"10.1177/10738584241236773","url":null,"abstract":"<p><p>Brain plasticity is the ability of the nervous system to change its structure and functioning in response to experiences. These changes occur mainly at synaptic connections, and this plasticity is named <i>synaptic plasticity</i>. During postnatal development, environmental influences trigger changes in synaptic plasticity that will play a crucial role in the formation and refinement of brain circuits and their functions in adulthood. One of the greatest challenges of present neuroscience is to try to explain how synaptic connections change and cortical maps are formed and modified to generate the most suitable adaptive behavior after different external stimuli. Adenosine is emerging as a key player in these plastic changes at different brain areas. Here, we review the current knowledge of the mechanisms responsible for the induction and duration of synaptic plasticity at different postnatal brain development stages in which adenosine, probably released by astrocytes, directly participates in the induction of long-term synaptic plasticity and in the control of the duration of plasticity windows at different cortical synapses. In addition, we comment on the role of the different adenosine receptors in brain diseases and on the potential therapeutic effects of acting via adenosine receptors.</p>","PeriodicalId":49753,"journal":{"name":"Neuroscientist","volume":" ","pages":"47-64"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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