Nursing Research最新文献

{"title":"Nursing Science and Environmental Determinants of Health: A Call for Environmental Health Nurse Scientists and Educators.","authors":"Olivia M Halabicky","doi":"10.1097/NNR.0000000000000871","DOIUrl":"10.1097/NNR.0000000000000871","url":null,"abstract":"","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":"75 2","pages":"83-87"},"PeriodicalIF":2.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12931846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147286048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing Science and the Humanities.","authors":"Rita H Pickler","doi":"10.1097/NNR.0000000000000881","DOIUrl":"https://doi.org/10.1097/NNR.0000000000000881","url":null,"abstract":"","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":"75 2","pages":"81-82"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147286058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profiles and Influencing Factors for Self-regulatory Fatigue in Patients With Colorectal Cancer.","authors":"Linyu Zhou, Tian Xiao, Ying Zheng, Chunmei Liu, Qiumei Ma, Fangyi Li, Ruihan Xiao, Biao He, Ao Tang, Xueqin Qiu, Xiaoju Chen","doi":"10.1097/NNR.0000000000000879","DOIUrl":"10.1097/NNR.0000000000000879","url":null,"abstract":"<p><strong>Background: </strong>Self-regulated fatigue (SRF) can seriously damage the physical and mental health of persons with colorectal cancer (CRC) undergoing chemotherapy. Understanding how to improve self-regulation ability is of crucial importance.</p><p><strong>Objectives: </strong>To investigate the status of potential profiles of SRF in persons with CRC treated with chemotherapy and the factors associated with these profiles.</p><p><strong>Methods: </strong>A convenience sampling method was used to conduct a questionnaire survey with 322 hospitalized persons with CRC who were undergoing chemotherapy at three tertiary-grade A hospitals in China. Data were collected through the General Information, Self-Regulatory Fatigue Scale, Family Health Scale, the 10-item Kessler Psychological Distress Scale, and Cancer Information Overload Scale. Latent profile analysis and multiple logistic regression were used to analyze the data.</p><p><strong>Results: </strong>SRF among persons undergoing chemotherapy for CRC could be divided into three potential profiles: low SRF-extensive social profile (53.1%), moderate SRF profile (32.3%), and high SRF-low mood profile (14.6%). Sex, per capita family monthly income, family health, psychological distress, and cancer information overload were predictive factors for different profiles of SRF.</p><p><strong>Discussion: </strong>There were three latent profiles of SRF in persons with CRC. Family health, psychological distress, and information overload were significant predictors of SRF. Health care providers should adopt individualized interventions to help patients improve disease coping, reduce SRF, and provide support through family care, information filtering, and psychological support.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"96-104"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mixed-Methods Study Exploring Motivation to Vape and Perception of Vaping Risk.","authors":"Kaitland A Brannon, Susan Brasher, Sharon M Close, Jeannie Rodriguez, Irene Yang","doi":"10.1097/NNR.0000000000000875","DOIUrl":"10.1097/NNR.0000000000000875","url":null,"abstract":"<p><strong>Background: </strong>Electronic cigarette (e-cigarette) use has surged globally, particularly among young adults and parents of young children. Though often perceived as a safer alternative to traditional cigarettes, concerns have grown regarding secondhand exposure, especially for children. Misconceptions about the safety of vaping may influence parental decisions to use e-cigarettes around their children.</p><p><strong>Objectives: </strong>To explore parental motivations for e-cigarette use and perceptions of the risks associated with vaping around children, using a mixed-methods approach.</p><p><strong>Methods: </strong>This explanatory sequential mixed-methods observational study combined quantitative survey data and qualitative focus group findings. Participants were daily e-cigarette users who were parents of children aged 4-12 years and lived in the same household. Participants completed self-report questionnaires assessing sociodemographic characteristics, motivations to vape, and perceived harms. Psychological dependence was assessed using the E-cigarette Dependence Scale (EDS). A subset participated in virtual focus groups, guided by a semistructured interview protocol. Quantitative data were analyzed using SPSS version 26; qualitative data were coded inductively and deductively using MAXQDA and analyzed thematically.</p><p><strong>Results: </strong>Survey participants were predominantly Black, single, low-income mothers with a mean age of 38 years and moderate to high nicotine dependence. Most participants reported initiating e-cigarette use as a smoking cessation strategy and believed vaping posed little to no health risks. Three qualitative themes emerged: (1) vaping as a means to stop smoking, (2) perceived belief that vaping is better than cigarette smoking, and (3) the power of addiction. Despite awareness of potential harms, participants described compulsive use and limited understanding of secondhand exposure risks to children.</p><p><strong>Discussion: </strong>Parental e-cigarette use is influenced by beliefs about harm reduction, smoking cessation goals, and nicotine dependence. Misconceptions about secondhand aerosol risks underscore the need for targeted health education. Interventions must consider both the psychological dependence and the socioeconomic context influencing parental vaping behaviors.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":"75 2","pages":"160-164"},"PeriodicalIF":2.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147286029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Racial Differences and Socioeconomic Status in Preterm Infant Neurodevelopment, Feeding, and Growth.","authors":"Tingting Zhao, Aolan Li, Weizi Wu, Jie Chen, Joan Combellick, Ming-Hui Chen, Xiaomei Cong","doi":"10.1097/NNR.0000000000000878","DOIUrl":"10.1097/NNR.0000000000000878","url":null,"abstract":"<p><strong>Background: </strong>Women from diverse socioeconomic status (SES) face a higher risk of preterm birth, increasing their infants' vulnerability to neurodevelopmental and other health disorders; however, the predictive role of maternal ZIP code level SES in these outcomes remains underexplored.</p><p><strong>Objectives: </strong>To investigate the associations between maternal racial disparity, ZIP code-level SES, and infant breastfeeding, growth, and neurodevelopmental trajectories.</p><p><strong>Methods: </strong>In this cohort study, preterm infants were recruited from two Connecticut neonatal intensive care units (NICUs). Infant demographic data, feeding regimens, and growth during the NICU stay were documented. Neurodevelopmental outcomes were assessed using the NICU Neonatal Neurobehavioral Scale, the Bayley scale of infant and toddler development (3rd ed.), and the Brief Infant Toddler Social Emotional Assessment. To compare SES differences between infants born to Black and White mothers, both t -tests and Wilcoxon tests were conducted. We used XGBoost to analyze infant health outcomes and SHapley Additive exPlanations (SHAP) values to identify SES-related risk factors associated with feeding, growth during NICU stay, and neurodevelopmental outcomes up to 2 years of age.</p><p><strong>Results: </strong>In total, 181 preterm infants from eight ZIP code areas were included in the study. The majority of infants were born to mothers who were White and non-Hispanic. Compared with infants born to White mothers, those born to Black mothers had younger birth gestational age (GA), lower birth weights, shorter birth lengths, smaller head circumferences, and higher Score of Neonatal Acute Physiology with Perinatal Extension-II (SNAPPE-II), with all differences being statistically significant. Compared with White mothers, Black mothers were younger, single, and less educated. Black mothers also had lower median household incomes, larger average family sizes, and higher levels of poverty compared with White mothers. Based on SHAP values, the risk factors predicting infants' feeding, growth, and neurodevelopment are ranked as follows: birth weight, birth GA, SNAPPE-II score, average family size, maternal age, median household income, poverty level, and school enrollment.</p><p><strong>Discussion: </strong>Maternal racial disparity and SES serve as predictors of feeding, growth, and neurodevelopmental outcomes in preterm infants. Understanding these associations can inform health care strategies for vulnerable preterm populations to improve long-term health outcomes.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"88-95"},"PeriodicalIF":2.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145858860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of the Motivators and Resources for Trauma Recovery Scale for Gender-based Violence Survivors.","authors":"Farida Bibi Mughal, Laura Sinko, Denise Saint Arnault","doi":"10.1097/NNR.0000000000000876","DOIUrl":"10.1097/NNR.0000000000000876","url":null,"abstract":"<p><strong>Background: </strong>Gender-based violence (GBV) has profound health effects on survivors, and there is a critical need to identify culturally relevant protective factors that support trauma recovery and healing.</p><p><strong>Objectives: </strong>To develop and validate the Motivators and Resources for Trauma Recovery (I-MOVE) scale to assess internal and external resources and motivators supporting trauma healing among GBV survivors across different cultural and social contexts.</p><p><strong>Methods: </strong>We used a structured, multiphase methodology for scale development, incorporating feedback from international experts and survivors. The I-MOVE tool was developed using a three-phase process: (1) identifying core domains through the extraction of relevant concepts from survivor narratives, (2) generating scale items using survivor language, and (3) assessing content and face validity, as well as evaluating acceptability, through a content validity index with experts and cognitive interviews with GBV survivors aged 30-60 from diverse cultural backgrounds.</p><p><strong>Results: </strong>The I-MOVE scale, consisting of 57 items, assesses resources and motivators crucial to trauma recovery. Expert evaluations and cognitive interviews ensured clarity, relevance, and cultural sensitivity.</p><p><strong>Discussion: </strong>The I-MOVE scale fills a critical gap by offering a culturally responsive tool to assess internal and external motivators of trauma recovery among GBV survivors. Its development incorporated multicultural survivor input, enhancing clarity and relevance across diverse populations. Unlike existing tools, I-MOVE addresses the full spectrum of healing resources, including legal status, parenting roles, and culturally appropriate services, particularly relevant for immigrants. These findings suggest the scale's strong potential to support survivor-centered care and inform targeted interventions across varied forms of GBV.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"121-128"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145758222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Workplace Violence, Bullying, Discrimination, Burnout, and Intention to Leave in Nursing.","authors":"Simon Paul P Navarro, Brianna Lin, Yilei Yang, Hyun Jin Jung, Allison A Norful","doi":"10.1097/NNR.0000000000000880","DOIUrl":"10.1097/NNR.0000000000000880","url":null,"abstract":"<p><strong>Background: </strong>While emerging literature has documented worsening staff nurse shortages due to higher prevalence of workplace violence, bullying, discrimination, and burnout among nurses post pandemic, there is limited evidence to identify specific work environment factors that either induce or mitigate nursing turnover intentions in relation to these workforce challenges.</p><p><strong>Objectives: </strong>This study aimed to evaluate nurses' experiences with workplace violence, bullying, discrimination, and burnout within work environments and examine their associations to determine their subsequent effects on nurses' intentions to leave.</p><p><strong>Methods: </strong>In 2024, we conducted a quantitative cross-sectional study using online, anonymous surveys with multiple validated instruments to gauge nurses' work environment perceptions, experiences with workplace violence, bullying, discrimination, burnout, and intent to leave. We used descriptive and inferential statistics to analyze the data collected from 222 nurses from New York State.</p><p><strong>Results: </strong>Of the 194 eligible nurses who completed our survey, most respondents had high exposure to negative acts or bullying and endorsed an intention to leave their jobs. Burnout, bullying, and discrimination experiences emerged as significant predictors of intention to leave. While workplace violence was reported to adversely affect personal well-being and mental health, it was not significantly associated with burnout or intention to leave. Nurses reported that their work environments need improvement, particularly in terms of staffing and leadership. Appropriate staffing has a significant association with workplace violence and reduces discrimination, bullying, and intention to leave perceptions. Although authentic leadership has substantial associations with workplace violence, bullying, and discrimination, it showed a lack of statistical significance on nurses' intention to leave. Notably, burnout was not significantly associated with the six essential standards for a healthy work environment.</p><p><strong>Discussion: </strong>The complex interplay among workplace violence, bullying, discrimination, and burnout highlights the importance of various work environment factors, such as appropriate staffing, meaningful recognition, and authentic leadership, in effectively shaping nurses' intentions to remain in or leave their jobs. Study results provide a foundation for health care organizations to conduct future research that centers on building more supportive and inclusive work environments to holistically sustain an efficient nursing workforce.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"129-137"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Theory Guided Analysis of Women's Toileting-Related Beliefs, Behaviors, and Bladder Health.","authors":"Sonya S Brady, Andrea Bilger, Kathryn L Burgio, Chloe Falke, Colleen M Fitzgerald, Aimee S James, Lisa Kane Low, Melissa Marquez, Diane K Newman, Sara Putnam, Todd Rockwood, Kyle D Rudser, Beverly R Williams, Jean F Wyman, D Yvette LaCoursiere","doi":"10.1097/NNR.0000000000000877","DOIUrl":"10.1097/NNR.0000000000000877","url":null,"abstract":"<p><strong>Background: </strong>Women commonly experience lower urinary tract symptoms (LUTS), such as frequent urination, urgent urination, and urinary incontinence. Health education for women rarely focuses on LUTS prevention and promotion of bladder health. The Theory of Reasoned Action and the Theory of Planned Behavior have been used to explain and change a variety of health behaviors. Missing from the literature is an explicit test of whether constructs of these theories are associated with LUTS and bladder health, and whether toileting habits explain this association.</p><p><strong>Objectives: </strong>To inform prevention strategies, this investigation tested whether the Theory of Reasoned Action and Theory of Planned Behavior constructs (attitudes toward, perceived norms of, and perceived control over specific toileting behaviors) are associated with women's toileting habits, and whether these habits mediate associations of theoretical constructs and women's LUTS and bladder health.</p><p><strong>Methods: </strong>The Prevention of Lower Urinary Tract Symptoms Research Consortium developed theoretical constructs to match four toileting behavior domains (delayed voiding, straining, crouching/hovering over toilets when away from home, and avoiding public toilets) assessed by the validated Toileting Behaviors: Women's Elimination Behaviors scale. Using a population-based survey, data were then collected from women at nine sites in the United States. Cross-sectional regression analyses tested whether toileting habits in a given domain mediated associations of corresponding theoretical constructs with reported LUTS, bladder health, and bladder function.</p><p><strong>Results: </strong>The overall analytic sample included 1,472 women with a mean age of 48 years. Associations of norms favoring delayed voiding and low perceived control over timing of voiding with more frequent LUTS and poorer bladder health and function were partially mediated by delayed voiding habits. Favorable attitudes toward and norms of straining (i.e., pushing down to urinate) and avoiding public toilets were associated with more frequent LUTS through corresponding toileting habits.</p><p><strong>Discussion: </strong>Longitudinal research is needed to confirm study findings. Future prevention intervention research may include nursing and public health messaging designed to shape attitudes toward and perceived norms of specific toileting behaviors, as well as policies to enhance control over healthy toileting practices in public spaces, including schools and workplaces.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"138-151"},"PeriodicalIF":2.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of a Gamified Mobile-Based Self-Management Intervention for Individuals With Nonspecific Chronic Lower Back Pain.","authors":"Se Jin Hong, Soyeon Park, Namsu Kim, Minsuh Chung, Youlee Jung, Joochul Lee, Kyounghae Kim","doi":"10.1097/NNR.0000000000000856","DOIUrl":"10.1097/NNR.0000000000000856","url":null,"abstract":"<p><strong>Background: </strong>Existing research fails to address the complex nature of nonspecific chronic lower back pain (cLBP) despite its detrimental effect on economic, societal, and medical expenditures.</p><p><strong>Objectives: </strong>We developed a nurse-led, mobile-delivered self-management intervention-Problem-Solving Pain to Enhance Living Well (PROPEL-M)-and evaluated its usability, feasibility, and initial efficacy for South Korean adults with nonspecific cLBP.</p><p><strong>Methods: </strong>This study was composed of two phases: (a) lab and field usability testing for a gamified mobile device application and (b) a pilot study employing a one-arm pretest-and-posttest design among adults aged 18-60 years with nonspecific cLBP. During the 2-week PROPEL-M intervention, participants used the gamified PROPEL application to watch 12 educational videos, engage in pain-relief activities and record daily pain and interference scores, and also participate in weekly yoga sessions and nurse consultations. In addition, participants wore a Fitbit for activity tracking, completed surveys, and underwent a quantitative sensory test to assess pain sensitivity. Blood samples were obtained for RNA sequencing.</p><p><strong>Results: </strong>The PROPEL gamified mobile application was refined during two-stage usability testing. In a pilot trial, 19 participants were recruited, all of whom completed the study. Satisfaction with the PROPEL-M, encompassing the application, yoga sessions, and nurse consultations, was rated as excellent. No adverse events were reported. Moreover, significant reductions were observed in the worst pain, average pain, current pain, and pain interference between baseline and the 2-week follow-up. We also found an increase in the heat-pain threshold at the pain site, measured by increasing thermal stimuli from 32°C until pain was rated 50 on a 0-100 scale.</p><p><strong>Discussion: </strong>The feasibility of the PROPEL-M was favorable despite concerns about the participants' burden associated with multidimensional data collection and diverse study-related activities. In the short term, the PROPEL-M demonstrated beneficial effects on pain intensity, interference, and heat-pain threshold, suggesting reduced sensitivity to heat stimuli. Comprehensive data on pain phenotypes and physical activity patterns collected through the PROPEL-M can support nurses in developing individualized self-management strategies, which may be further enhanced through nurse-led consultations.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"25-33"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainability of Complex Interventions: Recommendations From a Pragmatic Clinical Trial to Manage Cancer Symptoms.","authors":"Linda L Chlan, Jennifer L Ridgeway, Kathryn J Ruddy, Jessica D Austin, Sandra A Mitchell, Cindy Tofthagen, Deirdre R Pachman, Andrea L Cheville","doi":"10.1097/NNR.0000000000000870","DOIUrl":"10.1097/NNR.0000000000000870","url":null,"abstract":"<p><strong>Background: </strong>Sustained implementation of evidence-based practices and interventions in clinical settings is essential to ensure patients receive the best evidence-informed care. Information to guide sustainment of complex, multicomponent interventions in routine clinical practice after grant funding ends has had limited attention in the literature.</p><p><strong>Objectives: </strong>The purpose of this article is to describe the efforts of our multidisciplinary trial team to foster sustainment of key components of a complex electronic health record (EHR)-facilitated symptom surveillance and management intervention for people receiving cancer care at a Midwestern quaternary medical center or community practice settings.</p><p><strong>Methods: </strong>The parent Enhanced EHR-Facilitated Cancer Symptom Control (E2C2) hybrid Type II effectiveness-implementation pragmatic trial assessed the effectiveness of a multicomponent EHR-facilitated, collaborative care model-based intervention for management of SPPADE symptoms (sleep interference, pain, impaired physical function, anxiety, depression, and energy deficit/fatigue) and its implementation in medical oncology and community practice settings. The dynamic sustainability framework (DSF) posits the need for on-going efforts to continuously optimize the fit of an intervention within dynamic and evolving delivery contexts. This brief report uses the DSF to describe our team's efforts to optimize the fit of the core E2C2 intervention components to the practice setting and broader ecological system during the conduct of the trial. These activities were designed to achieve sustained implementation of the intervention in routine care delivery as the funded research activities concluded.</p><p><strong>Results: </strong>Core intervention components to be sustained were symptom surveillance using electronic patient-reported outcome measures, clinician alerts for severe symptoms, access to a registered nurse symptom care manager (RN SCM) for severe symptoms, patient education materials to support symptom self-management, access to a website of cancer-related materials, and the training and supervision of the RN SCMs.</p><p><strong>Discussion: </strong>Sustainability is dynamic and multidimensional, and emphasizes the importance of optimizing the fit of key intervention components to the care delivery context as it evolves time. Investigators are advised to plan sustainability efforts early, embrace change inherent in dynamic settings, and carefully track adaptations of intervention components to maximize intervention fit in real-world clinical practice to ensure patients continue to derive benefit from evidence-informed care.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"70-74"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12856733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145607193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}