Nursing ResearchPub Date : 2024-03-01Epub Date: 2023-10-19DOI: 10.1097/NNR.0000000000000696
Suzanne Crincoli, Pamela de Cordova, Charlotte Thomas-Hawkins, Linda Flynn, Peijia Zha, Knar Sagherian
{"title":"The Effects of Organizational Characteristics, Individual Nurse Characteristics, and Occupational Fatigue on Missed Care at Night.","authors":"Suzanne Crincoli, Pamela de Cordova, Charlotte Thomas-Hawkins, Linda Flynn, Peijia Zha, Knar Sagherian","doi":"10.1097/NNR.0000000000000696","DOIUrl":"10.1097/NNR.0000000000000696","url":null,"abstract":"<p><strong>Background: </strong>Missed care is defined as the omission or delay of necessary patient care and is internationally reported by nurses as a significant safety risk. Nurses working at night also report high levels of occupational fatigue that, coupled with inadequate staffing and practice environment support, may impede a nurse's ability to carry out the nursing process and lead to more missed care.</p><p><strong>Objective: </strong>The study's objective was to examine the interrelationships among organizational and nurse characteristics, occupational fatigue, and missed care among nurses working at night.</p><p><strong>Methods: </strong>A cross-sectional design was used. Participants included registered nurses (RNs) who worked at night in New Jersey acute care hospitals. Multiple linear regression and simple moderation analyses were performed to examine the associations.</p><p><strong>Results: </strong>Nurses reported missing necessary care at night. Unsupportive practice environments, high RN workloads, high patient-RN ratios, high chronic fatigue levels, and low intershift recovery were individually associated with missed care at night. High patient-to-RN ratios and chronic fatigue were independently associated with missed care. However, patient-to-registered-staffing levels had the most considerable effect on missed care at night. Nurses' years of experience and the number of hours of sleep between shifts were significant moderators of the relationship between occupational fatigue states and missed care.</p><p><strong>Discussion: </strong>This study is the first to examine the interrelationship between occupational fatigue levels, organizational and nurse characteristics, and missed care at night. There is an urgent need to implement strategies in hospital organizations that foster work schedules and adequate staffing patterns that lessen nurses' occupational fatigue levels to ensure our workforce's and patients' safety.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"101-108"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49684235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nursing ResearchPub Date : 2024-03-01Epub Date: 2023-11-09DOI: 10.1097/NNR.0000000000000706
Meghan O'Connell, Shelli L Feder, Uzoji Nwanaji-Enwerem, Nancy S Redeker
{"title":"Focus Group Study of Heart Failure Nurses' Perceptions of the Feasibility of Cognitive Behavioral Therapy for Insomnia.","authors":"Meghan O'Connell, Shelli L Feder, Uzoji Nwanaji-Enwerem, Nancy S Redeker","doi":"10.1097/NNR.0000000000000706","DOIUrl":"10.1097/NNR.0000000000000706","url":null,"abstract":"<p><strong>Background: </strong>People with heart failure (HF) often report insomnia with daytime consequences, including fatigue and decreased functional performance. Cognitive behavioral therapy for insomnia is an efficacious treatment, but few have access because of a shortage of trained sleep specialists. Access may be improved by offering it where people with HF receive care.</p><p><strong>Objectives: </strong>The purpose of this study was to explore the perceptions of nurses who specialize in HF regarding the value of cognitive behavioral therapy for insomnia to their patients, the feasibility of offering it in HF clinical settings, its delivery by nurses, and preferences for modes of delivery.</p><p><strong>Methods: </strong>We used a descriptive qualitative study design. We recruited focus group participants via e-mail to American Association of Heart Failure Nurses members and through requests for nurse collaborators to distribute within their networks. We conducted focus groups via Zoom. After describing cognitive behavioral therapy for insomnia and its efficacy for people with HF, we elicited perceptions about its value if provided in the HF outpatient clinical setting, facilitators and barriers to implementation, and other ways to increase access. We audio-recorded and transcribed the discussions. Two researchers coded the data and performed thematic analysis.</p><p><strong>Results: </strong>Four focus groups included 23 registered nurses and advanced practice nurses employed in outpatient HF clinics. We identified five themes: \"Insomnia Overlooked,\" \"Cognitive Behavioral Therapy for Insomnia Works,\" \"Nurses' Role,\" \"Barriers and Supports,\" and \"Modes of Delivery.\" Nurses endorsed the importance of insomnia to people with HF and the value of providing cognitive behavioral therapy. They expressed interest in evaluating and addressing sleep, the need for increased resources to address it, and multiple modes of delivery. All nurses believed they had a role in promoting sleep health but differed in their views about providing cognitive behavioral therapy for insomnia.</p><p><strong>Discussion: </strong>Nurses specializing in HF support the implementation of cognitive behavioral therapy for insomnia. Implementation studies are needed to identify effective methods to increase access to this efficacious treatment in outpatient HF clinical settings, including support and training for nurses who are interested and able to deliver it.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"109-117"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10922255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134650330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nursing ResearchPub Date : 2024-03-01Epub Date: 2024-01-06DOI: 10.1097/NNR.0000000000000708
Jung Eun Lee, Emily Haynes, Susan DeSanto-Madeya, Young Man Kim
{"title":"Social Determinants of Health and Multimorbidity Among Adults 50 Years and Older in the United States.","authors":"Jung Eun Lee, Emily Haynes, Susan DeSanto-Madeya, Young Man Kim","doi":"10.1097/NNR.0000000000000708","DOIUrl":"10.1097/NNR.0000000000000708","url":null,"abstract":"<p><strong>Background: </strong>Living with two or more chronic conditions simultaneously-known as multimorbidity-has become increasingly prevalent as the aging population continues to grow. However, the factors that influence the development of multimorbidity are still not fully understood.</p><p><strong>Objectives: </strong>The purpose of this study was to investigate the prevalence of multimorbidity among U.S. adults 50 years and older and identify associated factors with multimorbidity.</p><p><strong>Methods: </strong>We used data from four cycles from the National Health and Nutrition Examination Survey (2011-2018) to examine the associations between social determinants of health and multimorbidity among American adults aged 50 years and older. A set of variables on socioeconomic status and health behaviors was chosen based on the social determinants of health conceptual framework developed by the World Health Organization. In our study, 4,552 participants were included. All analyses were accounted for a complex survey design and the use of survey weights. Multiple logistic regression analyses were performed to examine the associated factors with multimorbidity.</p><p><strong>Results: </strong>The average age was 63.1 years, and 52.9% were female. The average number of chronic conditions was 2.27. The prevalence of multimorbidity was 63.8%, with high cholesterol and hypertension being the most prevalent conditions. In the adjusted model, age, gender, household income, citizenship status, health insurance, healthcare access, body mass index, and smoking status were found to be associated with living with multimorbidity.</p><p><strong>Discussion: </strong>Our results indicate that continued efforts aimed at promoting smoking cessation and maintaining a healthy weight will be beneficial in preventing the onset of chronic conditions. Additional research is warranted to gain a deeper understanding of the interrelationships between gender, race/ethnicity, household income, citizenship status, health insurance, and healthcare access as social determinants of health in the context of multimorbidity. Further research will help us develop targeted interventions and policies to address disparities and improve health outcomes for individuals with multimorbidity.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":"73 2","pages":"126-137"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139974223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nursing ResearchPub Date : 2024-03-01Epub Date: 2023-12-18DOI: 10.1097/NNR.0000000000000710
Amy R Newman, Karen M Moody, Kerri Becktell, Erin Connelly, Cynthia Holladay, Katie Parisio, Jonathan L Powell, Angela Steineck, Verna L Hendricks-Ferguson
{"title":"Ensuring Intervention Fidelity of an Attention Control Arm in a Multisite Randomized Controlled Trial.","authors":"Amy R Newman, Karen M Moody, Kerri Becktell, Erin Connelly, Cynthia Holladay, Katie Parisio, Jonathan L Powell, Angela Steineck, Verna L Hendricks-Ferguson","doi":"10.1097/NNR.0000000000000710","DOIUrl":"10.1097/NNR.0000000000000710","url":null,"abstract":"<p><strong>Background: </strong>Intervention fidelity is a critical element of randomized controlled trials, yet reporting of intervention fidelity among attention control arms is limited. Lack of fidelity to attention control procedures can affect study outcomes by either overestimating or underestimating the efficacy of the intervention under examination.</p><p><strong>Objectives: </strong>This brief report describes the approach researchers took to promote fidelity to the attention control arm of a pediatric palliative care randomized controlled trial funded by the National Institutes of Health.</p><p><strong>Methods: </strong>The Informational Meetings for Planning and Coordinating Treatment trial aims to determine the efficacy of a communication intervention that uses care team dyads (i.e., physicians partnered with nurses or advanced practice providers) to engage parents of children with cancer who have a poor prognosis in structured conversations about prognostic information, goals of care, and care planning. The intervention is compared with an attention control arm, which provides parents with structured conversations on common pediatric cancer education topics, such as talking to their child about their cancer, clinical trials, cancer treatment, side effects, and so forth. National Institutes of Health guidelines for assessing and implementing strategies to promote intervention fidelity were used to design (a) the attention control arm of a randomized controlled trial, (b) related attention control arm training, and (c) quality assurance monitoring.</p><p><strong>Results: </strong>Attention control study procedures were designed to mirror that of the intervention arm (i.e., same number, frequency, and time spent in study visits). Cluster randomization was used to allocate care team dyads to one arm of the randomized controlled trial. Care team dyads assigned to the attention control arm participated in online training sessions to learn attention control procedures, the different roles of research team members, and quality assurance methods. Fidelity to attention control procedures is assessed by both the interveners themselves and a quality assurance team.</p><p><strong>Discussion: </strong>Study design, training, and delivery are all critical to attention control fidelity. Baseline training often needs to be supplemented with booster training when time gaps occur between study start-up and implementation. Quality assurance procedures are essential to determine whether interveners consistently deliver attention control procedures correctly.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"166-171"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10922234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138802113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nursing ResearchPub Date : 2024-03-01Epub Date: 2023-10-31DOI: 10.1097/NNR.0000000000000704
Miriam N Weiss, Evelina Mocci, Shijun Zhu, Matthew J Davenport, Emily English, Cynthia L Renn, Susan G Dorsey
{"title":"Nociceptive and Transcriptomic Responses in a Swine Diabetic Wound Model Treated With a Topical Angiotensin 1 Receptor Antagonist.","authors":"Miriam N Weiss, Evelina Mocci, Shijun Zhu, Matthew J Davenport, Emily English, Cynthia L Renn, Susan G Dorsey","doi":"10.1097/NNR.0000000000000704","DOIUrl":"10.1097/NNR.0000000000000704","url":null,"abstract":"<p><strong>Background: </strong>Painful, treatment-resistant wounds are prevalent among diabetic patients and significantly affect health-related quality of life (HRQOL). Topical treatments may help alleviate pain without risk of dependence or side effects. However, there is a lack of topical wound compounds targeting pain-specific receptors. One possible target is proinflammatory angiotensin 1 receptor (AT1R), which is upregulated in diabetic skin and has been implicated in nociception.</p><p><strong>Objectives: </strong>We investigated the effects of topical valsartan, an AT1R antagonist, on pain (nociceptive thresholds) and gene expression changes (transcriptomics) in a swine model of diabetic wounds.</p><p><strong>Methods: </strong>Eight wounds were surgically induced in diabetic, hyperglycemic Yucatan miniature swine ( n = 4). Topical AT1R antagonist was applied to wounds on one side and vehicle on the other side. Nocifensive testing was conducted at baseline and then weekly, beginning 7 days after wound induction. Mechanical and thermal stimuli were applied to the wound margins until a nocifensive reaction was elicited or a predetermined cutoff was reached. After 7 weeks of testing, tissue from the dorsal horn, dorsal root ganglion, and wounds were sequenced and analyzed with DESeq2. Unbiased pathway analyses using Metascape were conducted on differentially expressed genes.</p><p><strong>Results: </strong>There was no significant difference in mechanical tolerance threshold between AT1R antagonist-treated and vehicle-treated wounds ( p = .106). Thermal tolerance was significantly higher in AT1R antagonist-treated wounds compared to vehicle-treated ( p = .015). Analysis of differentially expressed genes revealed enriched pathways of interest: interleukin-18 signaling in dorsal horn laminae IV-V and sensory perception of mechanical stimulus in wound tissue.</p><p><strong>Discussion: </strong>In this study, wounds modeling diabetic ulcers were created in hyperglycemic swine and treated with a topical AT1R antagonist. AT1R-antagonist-treated wounds had a higher tolerance threshold than vehicle-treated wounds for thermal hyperalgesia, but not mechanical allodynia. Pathway analyses of differentially expressed genes revealed several pathways of interest for future pain research. Although further studies are needed to confirm the findings, this study can improve nursing care by providing information about a potential future treatment that may be used to decrease pain and improve HRQOL in patients with diabetic wounds.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"118-125"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10922245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71428416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nursing ResearchPub Date : 2024-03-01Epub Date: 2023-10-31DOI: 10.1097/NNR.0000000000000702
Ariana M Chao, Thomas A Wadden, Wen Cao, Yingjie Zhou, Delphina Maldonado, Michelle I Cardel, Gary D Foster, James Loughead
{"title":"Randomized Controlled Trial of Effects of Behavioral Weight Loss Treatment on Food Cue Reactivity.","authors":"Ariana M Chao, Thomas A Wadden, Wen Cao, Yingjie Zhou, Delphina Maldonado, Michelle I Cardel, Gary D Foster, James Loughead","doi":"10.1097/NNR.0000000000000702","DOIUrl":"10.1097/NNR.0000000000000702","url":null,"abstract":"<p><strong>Background: </strong>It is not known whether behavioral weight loss can attenuate blood oxygen level-dependent responses to food stimuli.</p><p><strong>Objectives: </strong>This randomized controlled trial assessed the effects of a commercially available behavioral weight loss program (WW, WeightWatchers) compared to a wait-list control on blood oxygen level-dependent response to food cues.</p><p><strong>Methods: </strong>Females with obesity ( N = 61) were randomized to behavioral weight loss or wait-list control. At baseline and follow-up, participants completed assessments that included functional magnetic resonance imaging scans to assess response to images of high-calorie foods (HCF) or low-calorie foods (LCF), and neutral objects.</p><p><strong>Results: </strong>There were no significant between-group differences in change from baseline to follow-up in any regions of the brain in response to viewing HCF or LCF. From baseline to follow-up, participants in behavioral weight loss, compared with wait-list control, reported significantly greater increases in desire for LCF. Changes in liking and palatability of LCF and liking, palatability, and desire for HCF did not differ between groups.</p><p><strong>Discussion: </strong>Behavioral weight loss was associated with increased desire for LCF without changes in neural reactivity to food cues. These results suggest that alteration of neurological processes underlying responsiveness to food is difficult to achieve through behavioral weight management alone.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"91-100"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10922238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71428417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Depressive Symptoms in Young and Middle-Aged Stroke Patients: A Transition Analysis.","authors":"Zhiwei Liu, Zhenxiang Zhang, Jiajia Wang, Song Ge, Weihong Zhang, Dandan Xiang, Qingxuan Liu, Jemima Twumwaah Budu, Beilei Lin, Suyan Chen, Lihong Xue, Yongxia Mei","doi":"10.1097/NNR.0000000000000703","DOIUrl":"10.1097/NNR.0000000000000703","url":null,"abstract":"<p><strong>Background: </strong>There is heterogeneity in depressive symptoms. However, latent classes of depressive symptoms and the transition and influences of these in young and middle-aged stroke patients are unclear.</p><p><strong>Objectives: </strong>The aim of this study was to identify the latent classes of depressive symptoms and their transition patterns over time and the influencing factors in young and middle-aged stroke patients from stabilization to 6 months after discharge.</p><p><strong>Methods: </strong>This is a longitudinal study following the Strengthening the Reporting of Observational Studies in Epidemiology checklist. A total of 272 young and middle-aged stroke participants were recruited from a hospital neurology ward in Henan Province, China. Participants completed a questionnaire on sociodemographic and health information. Latent transition analysis was used to evaluate the transition pattern of latent classes from stabilization to 6 months after discharge and its influencing factors.</p><p><strong>Results: </strong>One hundred seventy-nine participants were included in the analysis. Three latent classes of depressive symptoms were identified as \"mild symptoms,\" \"grief-sleep-fatigue symptoms,\" and \"severe symptoms.\" Most participants remained in the original latent class from stabilization to 6 months after discharge (probability of 83.8%, 83.8%, and 88.8%). From 3 to 6 months after discharge, the participants with fewer complications were more likely to transition into the mild symptom class.</p><p><strong>Discussion: </strong>The findings indicate that from stabilization to 6 months after discharge, depressive symptoms in young and middle-aged stroke patients in China transitioned gradually from the severe symptom class to the mild symptom. Patients with fewer numbers of poststroke complications were more likely to transition to the mild symptoms class. Future research should focus on depressive symptoms in early-stage stroke patients and provide sufficient psychological support to patients with a high number of complications.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"149-157"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71428414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nursing ResearchPub Date : 2024-03-01Epub Date: 2024-01-06DOI: 10.1097/NNR.0000000000000712
Yen-Wen Liu, Chia-Chun Tang
{"title":"Health Beliefs, Protective Behaviors, and Information-Seeking.","authors":"Yen-Wen Liu, Chia-Chun Tang","doi":"10.1097/NNR.0000000000000712","DOIUrl":"10.1097/NNR.0000000000000712","url":null,"abstract":"<p><strong>Background: </strong>The outbreak of COVID-19 caused severe damage to public health globally and served as a stark reminder of the potential for future pandemics. Promoting protective behaviors to prevent the spread of any contagious disease thus remains a priority. Although research has shown that health beliefs can affect protective behaviors, few studies have examined the role of information-seeking in this relationship.</p><p><strong>Objectives: </strong>On the basis of the health belief model, this research focused on whether health beliefs affect personal protective behaviors through health information-seeking behaviors.</p><p><strong>Methods: </strong>This cross-sectional study with a causal-comparative design used an online questionnaire to investigate the Taiwanese public's health beliefs, protective behaviors, and information-seeking behaviors during the COVID-19 pandemic. Data were analyzed using descriptive statistics and multiple regression analysis.</p><p><strong>Results: </strong>Between September 2021 and January 2022, 322 valid questionnaires were collected. The results revealed that the effects of two health beliefs-self-efficacy and perceived benefits-on handwashing, social distancing, practicing good cough etiquette, and keeping one's environment clean and well ventilated were partially mediated by the frequency of official information-seeking.</p><p><strong>Discussion: </strong>Results of this study support the regular and timely promotion of pandemic prevention measures through official sites. Promoting official information-seeking can help enhance protective behaviors.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"158-165"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nursing ResearchPub Date : 2024-03-01Epub Date: 2023-12-18DOI: 10.1097/NNR.0000000000000707
Alberto Villaverde-Núñez, María Teresa Ramírez-López, Cristina Antón-Rodríguez, Inés Constanze Hammel, Cristina Pérez Ramos, Miriam Álvarez Villarreal, Sandra Ruíz Fernández, Beatriz Arriero López, Gema Hernández Cordobés, Nemesio Manzano Guerrero, Laura Baena Ruíz, María Isabel Guerra-Llamas
{"title":"Vaccination and Nutritional Outcomes of Hemodialysis Patients Infected With SARS-CoV-2.","authors":"Alberto Villaverde-Núñez, María Teresa Ramírez-López, Cristina Antón-Rodríguez, Inés Constanze Hammel, Cristina Pérez Ramos, Miriam Álvarez Villarreal, Sandra Ruíz Fernández, Beatriz Arriero López, Gema Hernández Cordobés, Nemesio Manzano Guerrero, Laura Baena Ruíz, María Isabel Guerra-Llamas","doi":"10.1097/NNR.0000000000000707","DOIUrl":"10.1097/NNR.0000000000000707","url":null,"abstract":"<p><strong>Background: </strong>Patients on hemodialysis are particularly vulnerable to COVID-19 and may have a reduced response to vaccination because of a decreased immune response. The nutritional status before or during the infection could also impact on the clinical effectiveness of vaccination.</p><p><strong>Objectives: </strong>We aim to describe the evolution of clinical and nutritional biomarkers of hemodialysis patients infected with SARS-CoV-2 and to assess their association with vaccination status.</p><p><strong>Methods: </strong>An observational, analytic, longitudinal, retrospective multicenter study was carried out in 82 patients on hemodialysis with SARS-CoV-2 infection. Nutritional status was assessed using the Geriatric Nutritional Risk Index (GNRI), anthropometry, and biochemical parameters. The association of the vaccine doses with clinical- and nutritional-related variables was also evaluated.</p><p><strong>Results: </strong>The percentage of vaccinated patients was similar to that of nonvaccinated patients. Before infection, most of the patients were malnourished. They presented lower albumin, creatinine, and urea levels than the well-nourished patients. Significant deterioration of nutritional status after infection was evidenced considering GNRI score, dry weight, and body mass index. Albumin and creatinine also decreased significantly after infection, whereas C-reactive protein increased in the acute phase. Significant inverse correlation was found between the variation of post-pre GNRI scores and basal albumin and C-reactive protein at 7 days. In addition, we observed the opposite trend between albumin at 30 days and basal cholesterol. A negative value in the GNRI variation was associated with bilateral pneumonia, need for hospitalization, and nutritional support. Vaccinated patients presented substantially less bilateral pneumonia and hospitalization. No significant effects were observed between vaccine doses and the variation in nutritional status, although a positive correlation was detected with the albumin at 7 days and C-reactive protein before infection and the number of vaccine doses received.</p><p><strong>Discussion: </strong>COVID-19 is associated with affectations in the nutritional status and biomarkers in hemodialysis patients. In this study, vaccines have shown a protective effect against the clinical consequences of COVID. However, they have shown limitations in preventing the deterioration of nutritional status after infection. The results highlight the importance of promoting the vaccination in these patients as well as incorporating nutritional assessment before, during, and after the infection.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"138-148"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138802503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mediation of Psychological Capital in Youth Experiencing Homelessness.","authors":"Lynn Rew, Natasha Slesnick, Shelli Kesler, Hyekyun Rhee","doi":"10.1097/nnr.0000000000000722","DOIUrl":"https://doi.org/10.1097/nnr.0000000000000722","url":null,"abstract":"Youth who experience homelessness engage in behaviors that place them at high risk for disease and injury. Despite their health risk behaviors, these youth display psychological capital, positive attributes of hope, efficacy, resilience, and optimism that motivate them to engage in health-promoting behaviors such as safer sex. However, this array of positive psychological attributes has not been studied in this vulnerable population.","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":"84 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140799550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}