Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine最新文献

{"title":"Polyuria in pregnancy: a case of relapsed central diabetes insipidus.","authors":"Sinéad Cadogan, Brendan Kinsley","doi":"10.20452/pamw.17365","DOIUrl":"10.20452/pamw.17365","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"136 7-8","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective dysfunction of E-series inflammation resolution in diabetes: E-series resolution dysfunction index as a novel biomarker in chronic coronary syndrome.","authors":"Beata Krasińska, Tomasz Urbanowicz, Ewelina Grywalska, Maciej Kurpisz, Andrzej Tykarski","doi":"10.20452/pamw.17343","DOIUrl":"10.20452/pamw.17343","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148399903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"All the iron, none of the red: diagnostic reasoning in autoimmune pure red cell aplasia.","authors":"Rodrigo Augsburger, Mariana Lagrutta, Roberto Parodi","doi":"10.20452/pamw.17368","DOIUrl":"10.20452/pamw.17368","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"136 7-8","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated alcohol‑related liver disease represent distinct clinical phenotypes and fibrosis risks: insights from a population-based Polish cohort.","authors":"Jerzy Jaroszewicz, Karol Żmudka, Marlena Dubatówka, Małgorzata Chlabicz, Paweł Sowa, Urszula Roszkowska, Damian Piotrowski, Karol Kamiński","doi":"10.20452/pamw.17338","DOIUrl":"10.20452/pamw.17338","url":null,"abstract":"<p><strong>Introduction: </strong>Metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated alcohol‑related liver disease (MetALD) are increasingly recognized conditions worldwide. However, epidemiologic data from Central and Eastern Europe are lacking.</p><p><strong>Objectives: </strong>This study aimed to assess the prevalence, clinical profiles, and liver fibrosis burden of MASLD and MetALD in a representative population from Central and Eastern Europe.</p><p><strong>Patients and methods: </strong>This study is part of the Bialystok PLUS (Polish Longitudinal University Study), an ongoing, prospective population‑based cohort study. A random sample of 2456 adult residents of the city of Białystok, Poland, was analyzed. Anthropometric, epidemiologic, clinical, and lifestyle‑related parameters were assessed. The participants were categorized into the MASLD, MetALD, and control groups. Differences in metabolic comorbidities and liver fibrosis severity were evaluated in each cohort.</p><p><strong>Results: </strong>The prevalence of MASLD was 22.72%, while MetALD accounted for 2.08% of the population. MASLD was predominantly associated with obesity and diabetes mellitus, whereas MetALD showed a higher prevalence of arterial hypertension and dyslipidemia. Significant liver fibrosis was more frequent in MetALD (17.8%) and MASLD (15.6%), as compared with the controls (5.1%; P <0.001 and P = 0.005, respectively). The highest cirrhosis rates were observed in 4.44% of the MetALD participants, 0.58% of the MASLD patients, and 0.12% of the controls (P = 0.001). Risk factors for significant fibrosis were analyzed across all groups.</p><p><strong>Conclusions: </strong>MASLD and MetALD represent a substantial and distinct health burden not only in the Polish population but likely across Central and Eastern Europe, given shared epidemiologic patterns of metabolic dysfunction and similar alcohol consumption. Understanding the interplay between these factors is crucial for improving diagnosis establishment, treatment strategies, and public health policies in this region.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148399831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Too tall, too young, too hypertensive: Abraham Lincoln disease in a 19‑year‑old patient. When should we suspect Marfan syndrome?","authors":"Agnieszka Tusznicka-Pawlak, Olgierd Dróżdż, Katarzyna Madziarska","doi":"10.20452/pamw.17364","DOIUrl":"10.20452/pamw.17364","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"136 7-8","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complement inhibition in kidney disease: lessons from success and failure.","authors":"Tomasz Stompór, Anna Pawłowska","doi":"10.20452/pamw.17370","DOIUrl":"10.20452/pamw.17370","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"136 7-8","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperglycemia metrics from continuous glucose monitoring are independently associated with platelet morphology in adults with type 1 diabetes.","authors":"Michał Kulecki, Dariusz Naskręt, Adrian Kubicki, Anna Lemańska, Sandra Moska, Paulina Haraś, Agata Grzelka-Woźniak, Aleksandra Uruska, Aleksandra Araszkiewicz, Dorota Zozulińska-Ziółkiewicz","doi":"10.20452/pamw.17312","DOIUrl":"10.20452/pamw.17312","url":null,"abstract":"<p><strong>Introduction: </strong>Platelet morphology indices are indirectly related to platelet reactivity and may link glycemic exposure to cardiovascular risk.</p><p><strong>Objectives: </strong>We aimed to investigate associations between continuous glucose monitoring (CGM)-derived metrics and platelet morphology in adults with type 1 diabetes mellitus (T1DM).</p><p><strong>Patients and methods: </strong>In this cross‑sectional study, we enrolled adults with T1DM without established cardiovascular disease. Platelet morphology indices were measured in fasting blood samples using the Sysmex XN‑1000 analyzer within 2 hours of blood collection. Glucose profiles were assessed using CGM over 7-, 14-, and 30‑day windows and calculated with GlyCulator 3.0. We used Spearman correlation and multivariable linear regression models adjusted for age, sex, body mass index, diabetes duration, C‑reactive protein, glomerular filtration rate, glycated hemoglobin, smoking, and platelet count.</p><p><strong>Results: </strong>We included 301 adults with T1DM (median [interquartile range] age, 33.1 [24.1-41] y, 44.5% men, diabetes duration, 13 [7-19] y). Platelet-large cell ratio (P‑LCR), mean platelet volume, and platelet distribution width correlated positively with mean glucose level (R = 0.27-0.3), time above range (TAR) level 2 (R = 0.25-0.29), glycemic risk index (R = 0.28-0.3), and mean amplitude of glucose excursion (MAGE; R = 0.2-0.22), and negatively with time in range (R = -0.25 to -0.3; all P <0.001), but not with hypoglycemia indices. In multivariable models, hyperglycemia‑related metrics remained independently associated with P‑LCR (standardized β, 1.37-1.59; ΔR², 0.014-0.024; P = 0.002); MAGE lost significance in the multivariable model after accounting for TAR level 2.</p><p><strong>Conclusions: </strong>In adults with T1DM, platelet morphology independently relates to cumulative hyperglycemic exposure rather than glycemic variability or hypoglycemia.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidisciplinary management of severe refractory hypoglycemia.","authors":"Alicja Rajewska, Paweł Komarnicki, Adam Maciejewski, Jan Musiałkiewicz, Paweł Gut, Marek Ruchała","doi":"10.20452/pamw.17317","DOIUrl":"10.20452/pamw.17317","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148220441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular risk factors, primary tumor origin, and carcinoid heart disease in patients with neuroendocrine tumors: a retrospective cross‑sectional study.","authors":"Piotr N Rudziński, Malwina Gonet, Jerzy Demkow, Jan Henzel, Sonia J Konsek-Komorowska, Mariola Pęczkowska","doi":"10.20452/pamw.17374","DOIUrl":"10.20452/pamw.17374","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dipeptidyl peptidase-4 inhibitor-associated mucous membrane pemphigoid leading to severe vision loss treated with rituximab.","authors":"Aleksandra Małolepsza, Aleksander Kostrzewa, Katarzyna Juczyńska, Agnieszka Żebrowska","doi":"10.20452/pamw.17323","DOIUrl":"10.20452/pamw.17323","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}