Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine最新文献

{"title":"Successful treatment of metachronous insulinoma in a patient with multiple endocrine neoplasia type 1 syndrome.","authors":"Alicja Szatko, Agata Toboła, Maryla Pelewicz-Sowa, Dorota Leszczyńska, Jolanta Kunikowska, Małgorzata Gietka-Czernel","doi":"10.20452/pamw.17031","DOIUrl":"10.20452/pamw.17031","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eruptive melanocytic nevi induced by anti-BRAF therapy.","authors":"Marta Marcinkiewicz-Florczak, Adrian Chwojnicki, Małgorzata Ploch-Glapińska, Jacek Szepietowski, Łukasz Matusiak","doi":"10.20452/pamw.17026","DOIUrl":"10.20452/pamw.17026","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TB or not TB: the clinical context must give us pause.","authors":"Marta Skoczyńska, Anna Panejko, Katarzyna Gruszecka","doi":"10.20452/pamw.17099","DOIUrl":"https://doi.org/10.20452/pamw.17099","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 7-8","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Independent and combined associations between exposure to ambient air pollutants and mortality: a case-crossover study.","authors":"Wenqiang Zhan, Liping Fang, Rongrong Han, Jieyu Zhang, Wu Wang, Xingxing Xu","doi":"10.20452/pamw.17036","DOIUrl":"10.20452/pamw.17036","url":null,"abstract":"<p><strong>Introduction: </strong>Previous studies suggest that short‑term exposure to air pollution is associated with an increased risk of mortality. However, understanding of the combined effects of exposure to various air pollutants on mortality is limited.</p><p><strong>Objectives: </strong>This study aimed to quantify a short‑term association between exposure to various air pollutants and death risk in the Qingpu District of Shanghai, and to evaluate the modifying effect of ambient temperature on this association.</p><p><strong>Patients and methods: </strong>We collected daily death records from 2013 to 2019 in the Qingpu District of Shanghai. A time‑stratified case crossover design and conditional logistic regression modeling were employed to estimate death risk associated with exposure to air pollutants. Additionally, we utilized weighted quantile sum regression to identify the predominant air pollutants influencing death risk.</p><p><strong>Results: </strong>For per 10 μg/m3‑increase in particulate matter less than or equal to 2.5 μm in diameter (PM2.5), 8‑hour moving average concentrations for ozone (O3‑8h), SO2, and NO2 concentrations, the odds ratio (95% CI) of nonaccidental death increased by a maximum of 1.009 (1.002-1.017), 1.017 (1.008-1.027), 1.051 (1.015-1.089), and 1.027 (1.010-1.045), respectively. A majority of air pollutants (excluding CO) were strongly associated with an elevated respiratory death risk, but only O3‑8h and SO2 were positively associated with cardiovascular death at lag‑2 day. There was a significant positive association between the exposure to mixtures of air pollutants and both nonaccidental and respiratory death, with PM2.5 and SO2 identified as major contributors, respectively. Furthermore, the detrimental effects of O3‑8h significantly intensified as temperatures rose.</p><p><strong>Conclusions: </strong>Environmental exposure to ambient air pollutants was associated with increased death risk, especially at high temperature.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimal hepatic encephalopathy: clinical implications for patients with hepatic cirrhosis.","authors":"Wojciech Pisarek, Jakub Jarmołowicz, Katarzyna Antosz-Popiołek, Elżbieta Poniewierka","doi":"10.20452/pamw.17054","DOIUrl":"10.20452/pamw.17054","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractory ascites and multinodular systemic involvement led to the discovery of an exceptional multivisceral form of vascular epithelioid tumor associated with the EWSR1::NFATC2 rearrangement.","authors":"Arthur Renaud, Louise Galmiche, Antoine Néel","doi":"10.20452/pamw.17093","DOIUrl":"https://doi.org/10.20452/pamw.17093","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 7-8","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corn starch in the therapy of paraneoplastic hypoglycemia.","authors":"Natalie Grosup Friedova, Otakar Semerad, Pavel Kohout","doi":"10.20452/pamw.17095","DOIUrl":"https://doi.org/10.20452/pamw.17095","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 7-8","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular disease and microbiome: focus on ischemic stroke.","authors":"István Szegedi, Dóra Bomberák, Zsolt Éles, Linda Lóczi, Zsuzsa Bagoly","doi":"10.20452/pamw.17088","DOIUrl":"10.20452/pamw.17088","url":null,"abstract":"<p><p>Cardiovascular and cerebrovascular diseases, encompassing conditions such as ischemic heart disease and ischemic stroke (IS), remain the leading global cause of death and disability. While traditional cardiovascular risk factors (eg, hypertension, diabetes, and atherosclerosis) are well established, emerging research underscores the critical role of gut microbiota in the development and progression of both cardiac and cerebrovascular events. The microbiota-gut-brain axis is a bidirectional communication system involving neural, immune, and metabolic pathways that link gut microbial activity to vascular and brain function. Dysbiosis, marked by reduced microbial diversity and an imbalance between beneficial and pathogenic taxa, has been associated with systemic inflammation, endothelial dysfunction, increased intestinal permeability, and thrombosis. Microbial metabolites, such as trimethylamine N‑oxide (TMAO), short‑chain fatty acids, and bile acid derivatives modulate blood-brain barrier integrity, vascular tone, and neuroinflammatory responses. Both cardiovascular and cerebrovascular diseases share key microbiota‑related mechanisms, including TMAO‑mediated platelet activation and low‑grade endotoxemia, although IS is more acutely affected by gut barrier disruption and neuroinflammation. In IS, gut dysbiosis also contributes to poststroke complications, such as hemorrhagic transformation, neuropsychiatric issues, and epilepsy. Advances in sequencing and metabolomics enabled identification of microbial signatures associated with the risk for an acute ischemic event and patient prognosis. Therapeutic strategies targeting the gut microbiota-including dietary interventions, probiotics, prebiotics, and synbiotics, fecal microbiota transplantation, and intestinal epithelial stem cell therapy-show promise in mitigating vascular injury and improving recovery. This narrative review highlights current insights into microbiota‑related cardiovascular and cerebrovascular events, with a focus on IS.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 7-8","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Citrullinated histone H3 in multiple myeloma patients: associations with prothrombotic fibrin clot properties.","authors":"Sylwia Trzpiot, Joanna Natorska, Michał Ząbczyk, Anetta Undas","doi":"10.20452/pamw.17073","DOIUrl":"10.20452/pamw.17073","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The gut as a mediator of environmental harm: unveiling microbial pathways in climate-related disease. Author's reply.","authors":"Michel Burnier","doi":"10.20452/pamw.17101","DOIUrl":"https://doi.org/10.20452/pamw.17101","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 7-8","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}