Małgorzata Pieniążek, Anna Mucha, Paulina Kapuścińska, Mirosława Püsküllüoğlu
{"title":"Distress patients with luminal advanced breast cancer receiving first-line endocrine therapy and CDK4/6 inhibitors: first analysis from a university-affiliated cancer center in Poland.","authors":"Małgorzata Pieniążek, Anna Mucha, Paulina Kapuścińska, Mirosława Püsküllüoğlu","doi":"10.20452/pamw.17070","DOIUrl":"https://doi.org/10.20452/pamw.17070","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kamila Bołtuć-Dziugieł, Robert Dziugieł, Sylwia Terpiłowska, Joanna Roskal-Wałek, Wojciech Dąbrowski, Andrzej Jaroszyński
{"title":"Oxidative stress in hemodialysis patients: shifting the focus from urea to osmolality.","authors":"Kamila Bołtuć-Dziugieł, Robert Dziugieł, Sylwia Terpiłowska, Joanna Roskal-Wałek, Wojciech Dąbrowski, Andrzej Jaroszyński","doi":"10.20452/pamw.17069","DOIUrl":"https://doi.org/10.20452/pamw.17069","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zuzanna Dybko, Jakub Bogda, Monika Mordak-Domagała, Krzysztof Zduniak, Zbigniew Podgajny, Jarosław Dybko
{"title":"Diagnostic challenges in a fatal case of atypically presenting peripheral T-cell lymphoma complicated by hemophagocytic lymphohistiocytosis.","authors":"Zuzanna Dybko, Jakub Bogda, Monika Mordak-Domagała, Krzysztof Zduniak, Zbigniew Podgajny, Jarosław Dybko","doi":"10.20452/pamw.17055","DOIUrl":"https://doi.org/10.20452/pamw.17055","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonia Borodzicz-Jażdżyk, Roel Hoek, Caitlin E M Vink, Geoffrey W de Mooij, Adriaan Wilgenhof, Luuk H G A Hopman, Mitchel Benovoy, Marco J W Götte
{"title":"Quantitative stress perfusion cardiovascular magnetic resonance: clinical implications for patients with suspected myocardial ischemia.","authors":"Sonia Borodzicz-Jażdżyk, Roel Hoek, Caitlin E M Vink, Geoffrey W de Mooij, Adriaan Wilgenhof, Luuk H G A Hopman, Mitchel Benovoy, Marco J W Götte","doi":"10.20452/pamw.16975","DOIUrl":"10.20452/pamw.16975","url":null,"abstract":"<p><strong>Introduction: </strong>Recent technical advances in stress perfusion cardiovascular magnetic resonance (CMR) imaging allow for myocardial blood flow (MBF) quantification (quantitative perfusion CMR [QP CMR]). However, clinical utility of QP CMR, as compared with conventional grayscale qualitative assessment (QA), is unknown.</p><p><strong>Objectives: </strong>The study aimed to compare the clinical conclusions on ischemia detection derived from QA of conventional grayscale stress perfusion CMR images and QP CMR in a real‑world population of patients with suspected myocardial ischemia.</p><p><strong>Patients and methods: </strong>This study retrospectively analyzed 101 patients with suspected myocardial ischemia referred for adenosine stress perfusion CMR imaging. QA of grayscale first‑pass perfusion CMR was performed by level 3 CMR experts. In QP assessment, stress and rest MBF (ml/g/min) were calculated for automatically determined myocardial segments. Each patient and coronary territory were classified by both QA and QP mapping, in a blind manner, as either ischemic or nonischemic.</p><p><strong>Results: </strong>QP assessment classified more coronary territories as ischemic than QA (46% vs 17%; P <0.001). In the per‑patient analysis, QP analysis identified myocardial ischemia in 64 patients (63%), and QA in 40 (40%; P <0.001). Ischemia was diagnosed by QA but not by QP analysis in 7% of the patients (QA+/QP-). In 31% of the patients, QP assessment established a new diagnosis of myocardial ischemia (QA-/QP+).</p><p><strong>Conclusion: </strong>QP CMR detects more ischemic coronary territories than QA and holds promise for identifying cases of myocardial ischemia that may be overlooked by QA alone in a real‑world patient population.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Banaszkiewicz, Paweł Kurzyna, Szymon Darocha, Michał Florczyk, Piotr Kędzierski, Michał Piłka, Rafał Mańczak, Piotr Szwed, Maria Wieteska-Miłek, Sebastian Szmit, Zbigniew Krasiński, Marcin Kurzyna
{"title":"Safety and outcomes of endovascular treatment with stent implantation in patients with malignant superior vena cava syndrome: single-center experience.","authors":"Marta Banaszkiewicz, Paweł Kurzyna, Szymon Darocha, Michał Florczyk, Piotr Kędzierski, Michał Piłka, Rafał Mańczak, Piotr Szwed, Maria Wieteska-Miłek, Sebastian Szmit, Zbigniew Krasiński, Marcin Kurzyna","doi":"10.20452/pamw.17003","DOIUrl":"10.20452/pamw.17003","url":null,"abstract":"<p><strong>Introduction: </strong>Superior vena cava syndrome (SVCS) comprises a range of symptoms and signs of mechanical obstruction of the SVC lumen.</p><p><strong>Objectives: </strong>The study aimed to investigate the effectiveness and safety of endovascular treatment (EVT) with stent implantation in patients with SVCS due to malignancy.</p><p><strong>Materials and methods: </strong>This retrospective observational study included patients with malignant SVCS who received EVT with stent implantation between July 2014 and November 2024. The efficacy of the procedure was evaluated based on technical success, clinical symptom relief, periprocedural complication rate, and recurrence rate, with follow‑up conducted 1 month postprocedure.</p><p><strong>Results: </strong>A total of 56 stents were implanted in 40 patients (57.5% women) in 47 procedures. Thirty‑three patients (81.5%) underwent conventional anticancer treatment prior to the procedure (previously treated patients [PTPs]) and 7 (17.5%) were naive to prior anticancer treatment (not previously treated patients [NPTPs]). The EVT with stent implantation was technically successful in 39 patients (97.5%). At least moderate reduction in symptoms was observed in 81.8% of the individuals in the PTP group and in 85.7% in the NPTP group (P = 0.67). In 28 patients (70%), only 1 stent was required. The overall complication rate was 12.5%. The primary stent patency rate was 92.3% (90.6% vs 100%; P = 0.41 for the PTP vs NPTP group, respectively).</p><p><strong>Conclusions: </strong>The EVT with stent placement is effective in symptomatic patients with SVCS due to malignancy. The procedure is associated with acceptable complication and reocclusion rates.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Izabela Zakrocka, Agnieszka Grzebalska, Adam Krusiński, Barbara Mackiewicz, Agnieszka Korolczuk, Wojciech Załuska
{"title":"A patient with Loeys-Dietz syndrome double-seropositive for antiglomerular basement membrane and antineutrophil cytoplasmic antibodies.","authors":"Izabela Zakrocka, Agnieszka Grzebalska, Adam Krusiński, Barbara Mackiewicz, Agnieszka Korolczuk, Wojciech Załuska","doi":"10.20452/pamw.17023","DOIUrl":"10.20452/pamw.17023","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The latest impact factor of Polish Archives of Internal Medicine is a huge success of Polish clinical science.","authors":"Anetta Undas","doi":"10.20452/pamw.17049","DOIUrl":"10.20452/pamw.17049","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 6","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emil Bik, Paweł Piluch, Artur Kośnik, Anna Stadnik, Jakub Grzybowski, Joann Raszeja-Wyszomirska
{"title":"Dual pattern of immune-related hepatotoxicity induced by pembrolizumab: hepatitis and sclerosing cholangitis.","authors":"Emil Bik, Paweł Piluch, Artur Kośnik, Anna Stadnik, Jakub Grzybowski, Joann Raszeja-Wyszomirska","doi":"10.20452/pamw.17008","DOIUrl":"10.20452/pamw.17008","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Krzysztof Rewiuk, Karolina Piotrowicz, Jakub Stokwiszewski, Beata Średniawa, Zbigniew Kalarus, Jarosław Kaźmierczak, Grzegorz Opolski, Tomasz Zdrojewski, Jerzy Gąsowski, Tomasz Grodzicki
{"title":"Association between atrial fibrillation and cognitive performance in older individuals.","authors":"Krzysztof Rewiuk, Karolina Piotrowicz, Jakub Stokwiszewski, Beata Średniawa, Zbigniew Kalarus, Jarosław Kaźmierczak, Grzegorz Opolski, Tomasz Zdrojewski, Jerzy Gąsowski, Tomasz Grodzicki","doi":"10.20452/pamw.17004","DOIUrl":"10.20452/pamw.17004","url":null,"abstract":"<p><strong>Introduction: </strong>Atrial fibrillation (AF) coexists with dementia in older population. AF often remains undiagnosed in its asymptomatic, silent form, that is, silent AF (SAF).</p><p><strong>Objectives: </strong>The aim of the study was to evaluate the relationships between cognitive performance and both symptomatic and asymptomatic AF, diagnosed via a long‑term (up to 30 days) wearable noninvasive electrocardiography monitoring system in a representative Polish population younger than 65 years.</p><p><strong>Patients and methods: </strong>A sample of 2203 participants from the cross‑sectional NOMED‑AF (Noninvasive Monitoring for Early Detection of Atrial Fibrillation) study were enrolled in the analyses (mean [SD] age, 77.1 years; 48.4% women), out of which 491 (22.3%) were diagnosed with AF (41.3%, with SAF).</p><p><strong>Results: </strong>Mean (SD) number of points obtained by the respondents in the Mini‑Mental State Examination (MMSE) was 25.8 (0.1), and it was lower in the patients with AF than those with sinus rhythm (25.2 [0.22] vs 26 [0.11]; P <0.001). Moreover, there was a difference in the number of points obtained by the patients with symptomatic AF and SAF, with the latter group having the lower score (25.8 [0.26] vs 24.3 [0.38]; P = 0.001). Finally, in a multivariable logistic regression model, the impact of SAF (but not that of symptomatic AF) on MMSE scores was demonstrated.</p><p><strong>Conclusions: </strong>In the older population, AF is associated with a lower MMSE score. In the case of SAF, this relationship is independent of other risk factors. This suggests the need for an active search for SAF in the group of patients with dementia and, on the other hand, screening for cognitive disorders in older patients with accidentally detected SAF.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Łukasz Mazurkiewicz, Maria M Joks, Monika Joks, Andrzej Szczepaniak, Lidia Gil, Joanna Rupa-Matysek
{"title":"Resistant thrombotic thrombocytopenic purpura successfully treated with caplacizumab in a patient with acute myeloid leukemia.","authors":"Łukasz Mazurkiewicz, Maria M Joks, Monika Joks, Andrzej Szczepaniak, Lidia Gil, Joanna Rupa-Matysek","doi":"10.20452/pamw.17016","DOIUrl":"10.20452/pamw.17016","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}