Aleksander Siniarski, Konrad Stępień, Karolina Golińska-Grzybała, Jarosław Trębacz, Maciej Stąpór, Barbara Szlósarczyk, Aleksandra Woźniak, Krzysztof P Malinowski, Grzegorz Gajos, Jadwiga Nessler, Jacek Legutko, Andrzej Gackowski
{"title":"Thrombin generation, fibrin clot permeation and lysis in patients with severe mitral regurgitation undergoing transcatheter edge-to-edge mitral valve repair: Mitral Fibrin Study.","authors":"Aleksander Siniarski, Konrad Stępień, Karolina Golińska-Grzybała, Jarosław Trębacz, Maciej Stąpór, Barbara Szlósarczyk, Aleksandra Woźniak, Krzysztof P Malinowski, Grzegorz Gajos, Jadwiga Nessler, Jacek Legutko, Andrzej Gackowski","doi":"10.20452/pamw.16755","DOIUrl":"10.20452/pamw.16755","url":null,"abstract":"<p><strong>Introduction: </strong>Intricate management of heart failure (HF), especially in the context of reduced ejection fraction, is further complicated by an elevated risk of thromboembolic events. Studies published so far offer inconclusive insight into the interplay between mitral regurgitation (MR) and the coagulation system.</p><p><strong>Objectives: </strong>This study aimed to investigate the impact of transcatheter edge‑to‑edge repair (TEER) on specific coagulation parameters in HF patients.</p><p><strong>Patients and methods: </strong>A cohort of 31 HF patients with severe MR treated with TEER underwent a systematic evaluation at 3 visits (V1, V2, and V3). Coagulation parameters, including fibrinogen concentration, thrombin generation, fibrin clot permeability, and clot lysis time (CLT) were assessed (n = 27 at V2; n = 25 at V3).</p><p><strong>Results: </strong>TEER induced changes in fibrinogen levels (P = 0.01; V3 vs V2) and improved fibrin clot properties over 50‑day follow‑up (P = 0.01; V3 vs V2). No significant differences were observed between time points in the analyzed blood clot parameters. Correlation analysis showed that baseline CLT was associated with ΔN‑terminal pro-B‑type natriuretic peptide (NT‑proBNP) level (P = 0.049; r = 0.4). Multivariable analysis identified baseline CLT as an independent predictor of early post‑TEER NT‑proBNP change (R2 = 0.55; P = 0.02).</p><p><strong>Conclusions: </strong>We found decreased level of fibrinogen and increased permeation coefficient over a median 50 (interquartile range, 32.5-75.5)-day post‑TEER follow‑up, as compared with early postprocedural assessments. Other blood coagulation parameters remained unchanged from baseline at both follow‑up time points after TEER. Finally, CLT was an independent predictor of early NT‑proBNP increase, emphasizing its role as an indicator of hemodynamic response to TEER.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140946054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Komisarz-Calik, Grzegorz Zieliński, Alicja Hubalewska-Dydejczyk, Aleksandra Gilis-Januszewska
{"title":"Challenges in management of giant prolactinoma in a young man.","authors":"Maria Komisarz-Calik, Grzegorz Zieliński, Alicja Hubalewska-Dydejczyk, Aleksandra Gilis-Januszewska","doi":"10.20452/pamw.16767","DOIUrl":"10.20452/pamw.16767","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marek Stopa, Katarzyna Zięba, Anna Tofilska, Grzegorz Bilo, Marek Rajzer, Agnieszka Olszanecka
{"title":"Is unattended automated office blood pressure measurement truly not superior to office blood pressure measurement in predicting hypertension-mediated organ damage? Authors' reply.","authors":"Marek Stopa, Katarzyna Zięba, Anna Tofilska, Grzegorz Bilo, Marek Rajzer, Agnieszka Olszanecka","doi":"10.20452/pamw.16824","DOIUrl":"10.20452/pamw.16824","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Janeczko, Agata Góral, Paweł Poznański, Aleksandra Zgryźniak, Dorota Kamińska, Magdalena Krajewska
{"title":"A rare case of preseptal orbital mucormycosis in a kidney transplant recipient.","authors":"Julia Janeczko, Agata Góral, Paweł Poznański, Aleksandra Zgryźniak, Dorota Kamińska, Magdalena Krajewska","doi":"10.20452/pamw.16816","DOIUrl":"https://doi.org/10.20452/pamw.16816","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna D Ciechomska, Ved Chaturvedi, Molly Thabah, Kei Ikeda, Richard J Wakefield, Bhaskar Dasgupta
{"title":"Integrating point of care ultrasound into rheumatology practice.","authors":"Anna D Ciechomska, Ved Chaturvedi, Molly Thabah, Kei Ikeda, Richard J Wakefield, Bhaskar Dasgupta","doi":"10.20452/pamw.16815","DOIUrl":"10.20452/pamw.16815","url":null,"abstract":"<p><p>A scenario-based probability approach integrating point of care rheumatology ultrasound (POCRUS) into rheumatology practice has recently been proposed as a teaching methodology to encourage greater awareness of US for practicing clinicians especially with respect to the management of overlapping clinical conditions. This article reviews the rheumatological areas where application of POCRUS substantially enhances clinical reasoning to confirm or exclude target conditions. It highlights the definitions of ultrasound-detected pathologies in rheumatoid arthritis (RA), spondylarthritis, gout and crystal arthritis, osteoarthritis, polymyalgia rheumatica and discusses the added value of POCRUS in diagnosing these conditions. It summarizes advances in predicting giant cell arteritis with sequential application of a probability score and ultrasonography. It discusses the potential for salivary gland ultrasound in the diagnostic workup of suspected Sjogren's syndrome. Other areas for POCRUS application such as in suspected nerve entrapment are reviewed.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karolina Snopek-Miśta, Wojciech Zarębski, Katarzyna Steinhof-Radwańska, Piotr Paleń, Joanna Lorek, Andrzej Lorek
{"title":"Metastasis to the male breast from squamous cell lung carcinoma 18 months after radical surgical treatment.","authors":"Karolina Snopek-Miśta, Wojciech Zarębski, Katarzyna Steinhof-Radwańska, Piotr Paleń, Joanna Lorek, Andrzej Lorek","doi":"10.20452/pamw.16811","DOIUrl":"https://doi.org/10.20452/pamw.16811","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karolina Niezabitowska, Zuzanna Nowak, Katarzyna Siek, Tadeusz Popiela, Marcin Krzanowski, Katarzyna Krzanowska
{"title":"Fournier's gangrene with abdominal wall cellulitis probably caused by animal microbiota after insulin injection.","authors":"Karolina Niezabitowska, Zuzanna Nowak, Katarzyna Siek, Tadeusz Popiela, Marcin Krzanowski, Katarzyna Krzanowska","doi":"10.20452/pamw.16813","DOIUrl":"https://doi.org/10.20452/pamw.16813","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zuzanna Wojtczak, Michał Sajdek, Krzysztof Lamparski, Rafał Maciąg, Magdalena Januszewicz, Zbigniew Gałązka
{"title":"Conquering the giant: successful endovascular treatment of renal arteriovenous fistula.","authors":"Zuzanna Wojtczak, Michał Sajdek, Krzysztof Lamparski, Rafał Maciąg, Magdalena Januszewicz, Zbigniew Gałązka","doi":"10.20452/pamw.16812","DOIUrl":"https://doi.org/10.20452/pamw.16812","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}