Bogusława Ołpińska, Maria Łoboz-Rudnicka, Barbara Barbara, Rafał Wyderka, Krystyna Łoboz-Grudzień, Joanna Jaroch
{"title":"Impact of carotid arterial stiffness on 5-year prognosis in patients with myocardial infarction: a preliminary study.","authors":"Bogusława Ołpińska, Maria Łoboz-Rudnicka, Barbara Barbara, Rafał Wyderka, Krystyna Łoboz-Grudzień, Joanna Jaroch","doi":"10.20452/pamw.17034","DOIUrl":"10.20452/pamw.17034","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karolina Golińska-Grzybała, Jarosław Trębacz, Maciej Stąpór, Krzysztof Boczar, Andrzej Ząbek, Andrzej Gackowski
{"title":"Successful edge-to-edge repair of iatrogenic tricuspid regurgitation related to pacemaker lead extraction.","authors":"Karolina Golińska-Grzybała, Jarosław Trębacz, Maciej Stąpór, Krzysztof Boczar, Andrzej Ząbek, Andrzej Gackowski","doi":"10.20452/pamw.17037","DOIUrl":"10.20452/pamw.17037","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weronika Ziemińska, Artur Kośnik, Jan Domański, Anna Stadnik, Jakub Grzybowski, Joanna Raszeja-Wyszomirska
{"title":"Atypical hepatic fat sparing as a radiological red flag: a rare presentation of hepatocellular carcinoma in a noncirrhotic patient.","authors":"Weronika Ziemińska, Artur Kośnik, Jan Domański, Anna Stadnik, Jakub Grzybowski, Joanna Raszeja-Wyszomirska","doi":"10.20452/pamw.17038","DOIUrl":"10.20452/pamw.17038","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pyrexia puzzle: take a closer look to solve the mystery.","authors":"Radwa Genidy, Aymen Abbas, Waqar Gaba","doi":"10.20452/pamw.17094","DOIUrl":"https://doi.org/10.20452/pamw.17094","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 7-8","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kidney disease… Is it worth the weight?","authors":"Peter J Todd, Niall Leonard","doi":"10.20452/pamw.17092","DOIUrl":"https://doi.org/10.20452/pamw.17092","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 7-8","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalia Krajewska, Damian Waląg, Łukasz N Kołtowski
{"title":"Myocardial infarction with nonobstructive coronary arteries: clinical characteristics and role of the N-terminal pro-B-type natriuretic peptide to troponin ratio as a novel diagnostic tool.","authors":"Natalia Krajewska, Damian Waląg, Łukasz N Kołtowski","doi":"10.20452/pamw.17051","DOIUrl":"10.20452/pamw.17051","url":null,"abstract":"<p><strong>Introduction: </strong>Myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) encompasses heterogeneous conditions resulting in myocardial damage without significant coronary artery obstruction. Understanding its prevalence and risk factors is essential for developing diagnostic and therapeutic strategies.</p><p><strong>Objectives: </strong>This study aimed to evaluate the prevalence, outcomes, and risk factors of MINOCA and to investigate the N‑terminal pro-B‑type natriuretic peptide (NT‑proBNP) to troponin ratio as a novel early diagnostic tool.</p><p><strong>Patients and methods: </strong>This single‑center, retrospective study included 194 patients with acute coronary syndrome diagnosed on invasive coronary angiography (ICA) over 6 months. The patients were categorized as MINOCA or obstructive or occlusion MI (OOMI) based on ICA and optical coherence tomography findings. Detailed data on clinical characteristics, laboratory test results, NT‑proBNP/troponin ratio, and the SYNTAX score were collected.</p><p><strong>Results: </strong>Among the 194 patients, 43 (22%) were diagnosed with MINOCA. Men were more frequently diagnosed with OOMI than MINOCA (120 [79%] vs 24 [56%]; P = 0.003). A history of cancer was more common in the MINOCA than the OOMI group (23% vs 10%; P = 0.04), while peripheral artery disease and dyslipidemia were less prevalent in the patients with MINOCA (9% vs 97%; P <0.001 and 26% vs 49%; P = 0.01, respectively). MINOCA patients had higher systolic blood pressure (SBP) on admission (median [interquartile range, IQR], 154 [140-167] vs 140 [126-158] mm Hg); P <0.04), while patients with OOMI exhibited higher levels of total cholesterol, low-density lipoprotein cholesterol, and troponin. The NT‑proBNP/troponin ratio was higher in the MINOCA patients than in the individuals with OOMI (median [IQR], 6.53 [1.28-17.25] vs 1.04 [0.15-3.65]; P <0.001). Furthermore, the ratio effectively distinguished MINOCA from OOMI, as reflected by an area under the curve value of 0.739. It was also a significant predictor of MINOCA (odds ratio, 1.153; 95% CI, 1.04-1.34; P = 0.02).</p><p><strong>Conclusions: </strong>This study provides a comprehensive clinical profile of patients with MINOCA (female sex, a history of cancer, higher SBP), which may help support hypotheses for future prospective studies. The NT‑proBNP/troponin ratio emerges as a promising tool for early differentiation of MINOCA patients, warranting further research.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matija Kozak, Benilde Cosmi, Grigoris Gerotziafas, Peter Marschang, Agata Stanek
{"title":"Venous thromboembolism in pregnancy: recent advances.","authors":"Matija Kozak, Benilde Cosmi, Grigoris Gerotziafas, Peter Marschang, Agata Stanek","doi":"10.20452/pamw.17081","DOIUrl":"10.20452/pamw.17081","url":null,"abstract":"<p><p>Venous thromboembolism (VTE) is notably more common in pregnancy, with at least a 5‑fold higher risk than in nonpregnant women, and an even greater surge postpartum. Pregnancy induces a hypercoagulable state with venous stasis and vascular changes, making VTE a leading cause of maternal morbidity and mortality, particularly in the postpartum period. Clinical presentation is often subtle or nonspecific, highlighting the need for objective diagnostic strategies adapted to pregnancy. Emerging diagnostic algorithms, including D‑dimer-guided approaches and pregnancy‑specific rules, such as the pregnancy‑adapted YEARS criteria, are improving diagnostic accuracy while limiting unnecessary imaging. Prevention and treatment regimens are tailored to pregnant patients, with low‑molecular‑weight heparin remaining the cornerstone of therapy. Ongoing research is exploring individualized prophylaxis based on personal risk profiles, biomarker‑driven risk stratification, and optimized postpartum management protocols. Under‑recognized issues, such as superficial vein thrombosis and rare but high‑risk thrombophilias (eg, antithrombin deficiency) are also garnering attention for their contribution to pregnancy‑associated VTE risk. This review provides a comprehensive update on pregnancy‑related VTE, highlighting evolving concepts in epidemiology, diagnosis, prevention, and management of deep and superficial venous thromboses and pulmonary embolism from pregnancy through the postpartum period.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandra Kwapiszewska-Szybalska, Łukasz Zandecki, Marcin Sadowski, Michał Skrzypek, Krzysztof Wilczek, Mateusz Tajstra, Wojciech Wojakowski, Krzysztof Milewski, Jacek Kurzawski, Marianna Janion, Mariusz Gąsior
{"title":"Coronary revascularization in patients with ST-segment elevation myocardial infarction and multivessel disease: 2-year follow-up from a large multicenter registry.","authors":"Aleksandra Kwapiszewska-Szybalska, Łukasz Zandecki, Marcin Sadowski, Michał Skrzypek, Krzysztof Wilczek, Mateusz Tajstra, Wojciech Wojakowski, Krzysztof Milewski, Jacek Kurzawski, Marianna Janion, Mariusz Gąsior","doi":"10.20452/pamw.17030","DOIUrl":"10.20452/pamw.17030","url":null,"abstract":"<p><strong>Introduction: </strong>Multivessel coronary artery disease (MVD) occurs in one‑third of patients with ST‑segment elevation myocardial infarction (STEMI) who undergo primary percutaneous coronary intervention (pPCI). However, long‑term prognosis and readmission rates in this high‑risk group remain unclear.</p><p><strong>Objectives: </strong>We aimed to evaluate the long‑term risk of cardiovascular events and readmissions in STEMI patients with MVD.</p><p><strong>Patients and methods: </strong>This prospective observational study included 1513 patients enrolled in the Silesian Cardiovascular Database between 2017 and 2020. We analyzed demographic, clinical, and angiographic characteristics along with prognosis during 2‑year follow‑up.</p><p><strong>Results: </strong>A total of 439 patients with MVD were identified in the registry. Among them, 2‑vessel disease (2‑VD) was detected in 329 patients (74.9%) and 3‑vessel disease (3‑VD) in 110 (25.1%). During 2‑year follow‑up, overall survival and the incidence of major adverse cardiovascular events (death, MI, stroke) were similar in both groups. In multivariable analyses, previous MI (hazard ratio [HR], 1.63; 95% CI, 1.01-2.63; P = 0.04) and the left main coronary artery as the infarct‑related artery (IRA; HR, 3.22; 95% CI, 1-10.38; P = 0.049) increased the risk of unplanned cardiac readmissions, whereas clopidogrel use (HR, 1.45; 95% CI, 1.07-1.95; P = 0.01) increased the risk of all‑cause readmissions. PCI of a non‑IRA during the index hospitalization was associated with a lower risk of both unplanned cardiac (HR, 0.61; 95% CI, 0.42-0.9; P = 0.01) and all‑cause (HR, 0.61; 95% CI, 0.46-0.82; P = 0.001) readmissions.</p><p><strong>Conclusions: </strong>Two‑year overall survival and event‑free survival were similar in STEMI patients with 2‑VD and 3‑VD. The use of more potent antiplatelets instead of clopidogrel as well as non‑IRA revascularization during the index hospitalization appear to be important for minimizing readmission rates.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Piotr Jemielita, Gregory Y H Lip, Michał Święczkowski, Anna Kurasz, Adrianna Krepsztul-Jemielita, Sławomir Dobrzycki, Łukasz Kuźma
{"title":"Light pollution exposure and a risk of hospitalization for cardiovascular disease in Poland: a population-based study (EP-PARTICLES study).","authors":"Piotr Jemielita, Gregory Y H Lip, Michał Święczkowski, Anna Kurasz, Adrianna Krepsztul-Jemielita, Sławomir Dobrzycki, Łukasz Kuźma","doi":"10.20452/pamw.17064","DOIUrl":"10.20452/pamw.17064","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiovascular diseases (CVDs) remain the leading cause of death worldwide. Recently, attention has expanded beyond traditional risk factors to include nonclassical ones, such as light pollution (LP).</p><p><strong>Objectives: </strong>This study aimed to assess the impact of LP exposure on hospitalizations due to CVDs.</p><p><strong>Methods: </strong>Data from the years 2012-2020 on light and air pollution were obtained from the Suomi NPP satellite, Copernicus System, and local monitoring stations. Hospitalization data for new‑onset cases of ST‑segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI), atrial fibrillation (AF), and ischemic stroke (IS; based on the International Classification of Diseases, Tenth Revision codes) were obtained from the Polish National Health Fund. The analysis covered 101 counties in 5 eastern Poland voivodeships, using sex- and age‑standardized incidence rates and panel Poisson regression models. Confounding variables included air pollution, socioeconomic status, and meteorological factors.</p><p><strong>Results: </strong>The study included 55 081 hospitalizations for STEMI (64.6% men; mean [SD] age, 67.5 [12.5] y), 69 112 for NSTEMI (60.9% men; mean [SD] age, 70.2 [11.9] y), 228 410 for AF (47.3% men; mean [SD] age, 69.6 [11.2] y), and 131 085 for IS (48.4% men; mean [SD] age, 73.9 [12.2] y). LP intensity was calculated as an area‑weighted county‑level yearly average. An increase by one interquartile range (2479.42 nW/cm²/sr) in LP was linked to a 7% rise in odds of hospitalization for acute IS (odds ratio [OR], 1.07; 95% CI, 1.05-1.1) and a 15% rise for acute AF (OR, 1.15; 95% CI, 1.13-1.17) in models with the highest number of confounding variables included. Significance for STEMI and NSTEMI was found in some models.</p><p><strong>Conclusions: </strong>Prolonged LP exposure may increase the odds of cardiovascular hospitalizations, especially for IS or AF.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prehabilitation: ready to be served?","authors":"Jann Arends","doi":"10.20452/pamw.17103","DOIUrl":"10.20452/pamw.17103","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 7-8","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}