Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine最新文献

{"title":"How to manage adrenal incidentaloma in a hypertensive patient?","authors":"Agnieszka Łebek-Szatańska, Andrzej Januszewicz, Sylwia Kołodziejczyk-Kruk, Marek Kabat, Mateusz Śpiewak, Magdalena Januszewicz","doi":"10.20452/pamw.16949","DOIUrl":"10.20452/pamw.16949","url":null,"abstract":"<p><p>Adrenal incidentaloma (AI) is a mass discovered on imaging not performed for suspected adrenal diseases. Technological advancements and increasing availability of imaging modalities, along with a growing awareness of preventive care and an aging population, have led to an increase in AI detection, generating diagnostic and therapeutic dilemmas for clinicians. Every patient with AI should undergo a careful evaluation to establish the etiology of the tumor and detect all hormonally active lesions, including those that cause secondary hypertension. Hormonal hypertension carries a higher risk of cardiovascular complications and target organ damage than essential hypertension, independently of blood pressure control. In this review, we discuss the current 2023 European Society of Endocrinology guidelines on the management of AIs in the context of other expert documents (including recommendations of the Polish Society of Endocrinology), with the main focus on 2 secondary forms of hypertension-primary aldosteronism and pheochromocytoma-that should not be missed in clinical practice.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The diverticular inflammation and complication assessment classification: ready to use, easy to use, must be used.","authors":"Antonio Tursi","doi":"10.20452/pamw.16963","DOIUrl":"10.20452/pamw.16963","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 2","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive analysis of lipidome patterns in gestational diabetes mellitus risk assessment.","authors":"Marija Sarić Matutinović, Aleksandra Zeljkovic, Jelena Vekic, Daniela Ardalic, Željko Mikovic, Aleksandra Stefanovic","doi":"10.20452/pamw.16953","DOIUrl":"10.20452/pamw.16953","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetic ketoacidosis leading to a diagnosis of medullary thyroid carcinoma and chronic lymphocytic leukemia: an extremely rare and unexpected case.","authors":"Aleksandra W Bratborska, Joanna Rupa-Matysek, Małgorzata Janicka-Jedyńska, Maciej Cymerys","doi":"10.20452/pamw.16906","DOIUrl":"10.20452/pamw.16906","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of cardiovascular comorbidities in psoriatic arthritis: relationship with clinical phenotype and treatment in a real-life study.","authors":"Jarosław Nowakowski, Piotr Kuszmiersz, Grzegorz Biedroń, Zofia Guła, Magdalena Strach, Glenn Haugeberg, Mariusz Korkosz","doi":"10.20452/pamw.16911","DOIUrl":"10.20452/pamw.16911","url":null,"abstract":"<p><strong>Introduction: </strong>The relationship between the phenotype and treatment of psoriatic arthritis (PsA) and the increased prevalence of cardiovascular comorbidities is not well studied.</p><p><strong>Objective: </strong>The aim of this study was to assess the prevalence of cardiovascular comorbidities in relation to the clinical phenotype and treatment of PsA.</p><p><strong>Methods: </strong>This was a cross‑sectional, real‑life study. Demographic and clinical data were recorded in patients with PsA. The relationships between clinical phenotypes (axial, oligoarthritis, polyarthritis, and mixed), cardiovascular risk factors, comorbidities, and treatment were analyzed.</p><p><strong>Results: </strong>Among the 267 patients studied, no differences were found in the prevalence of cardiovascular risk factors or comorbidities in relation to the clinical phenotypes of PsA. However, the patients with oligoarthritis more frequently had hypertension (38.8% vs 22%; P = 0.01). The patients with any cardiovascular disease were more often receiving treatment with glucocorticosteroids (17.9% vs 4.8%; P = 0.001) as well as were exposed to them in the past (22.6% vs 13%; P = 0.02). As many as 83.3% of the patients currently on nonsteroidal anti‑inflammatory drugs (NSAIDs) had heart failure (HF), while among those without HF, NSAIDs were taken by 35.3% (P = 0.03). A total of 15.4% of the patients were diagnosed with dyslipidemia but low‑density lipoprotein cholesterol level above 3 mmol/l was detected in 36.6% of the participants. A multivariable logistic regression analysis identified the current use of glucocorticosteroids and oligoarthritis as predictive factors for cardiovascular comorbidities.</p><p><strong>Conclusion: </strong>The use of glucocorticoids and NSAIDs is associated with an increased prevalence of cardiovascular comorbidities in patients with PsA and should be avoided. Oligoarthritis and current use of glucocorticosteroids are predictors of cardiovascular comorbidities. Hyperlipidemia remains underrecognized in patients with PsA in a real‑world context.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics and outcomes of young patients with acute myocardial infarction: the YAMI registry.","authors":"Zofia Kampka, Radosław Szczerba, Karolina Bula, Małgorzata Cichoń, Michał Wita, Katarzyna Mizia-Stec, Krystian Wita, Maciej T Wybraniec","doi":"10.20452/pamw.16921","DOIUrl":"10.20452/pamw.16921","url":null,"abstract":"<p><strong>Introduction: </strong>Premature myocardial infarction (MI) is characterized by diverse pathophysiology. Despite its low prevalence, it bears serious health and social consequences.</p><p><strong>Objectives: </strong>The aim of the study was to evaluate young MI patients (≤45 years) in terms of clinical characteristics and long‑term outcomes.</p><p><strong>Patients and methods: </strong>This is an observational study including 221 patients aged 45 years or younger (women, 16.7%; mean [SD] age, 38.4 [4.8] years) hospitalized due to acute MI between January 2017 and April 2023. Data were extracted from the Academic Repository of Clinical Cases of Medical University of Silesia. The young MI patients were compared with a representative MI cohort older than 45 years (n = 2256). The mean (SD) follow‑up was 648.7 (178.7) days. The primary end point was all‑cause mortality.</p><p><strong>Results: </strong>The patients with MI aged up to 45 years were predominantly men (83.3%), and were characterized by lower mortality (7.2% vs 15%; log‑rank P = 0.01), shorter hospitalization time (median [interquartile range], 4 [3-6] vs 5 [3-6] days; P = 0.03), and less pronounced cardiovascular risk factors than the older group. The Cox regression analysis showed that in the MI patients aged up to 45 years, occurrence of peri‑MI sudden cardiac arrest, Q wave presence, higher volume of contrast, and a lack of qualification for cardiac rehabilitation (CR) were independent predictors of mortality. In 15.8% of the younger cohort, MI was unrelated to ruptured atheroma. The patients with nonclassic MI pathophysiology were younger, more often female, more frequently presented with acute non-ST‑segment elevation MI, had lower prevalence of hyperlipidemia and hypertension, and were less often referred for percutaneous coronary intervention and CR, and more often for optical coherence tomography and cardiac magnetic resonance imaging, as compared with the individuals with classic MI.</p><p><strong>Conclusions: </strong>Young MI patients have a favorable prognosis and frequently present with atypical MI pathophysiology. Participation in CR is of utmost importance in mortality reduction regardless of patient age.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular comorbidities in psoriatic arthritis: real-life data.","authors":"Paraskevi V Voulgari, Alexandros A Drosos","doi":"10.20452/pamw.16965","DOIUrl":"10.20452/pamw.16965","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"135 2","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bloodless, lytic-free, large-bore mechanical thrombectomy for the treatment of acute pulmonary embolism: the first Polish experience with the FlowTriever system.","authors":"Jakub Stępniewski, Kamil Jonas, Wojciech Magoń, Michał Karnaś, Weronika Chaba, Grzegorz Kopeć","doi":"10.20452/pamw.16880","DOIUrl":"10.20452/pamw.16880","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left main percutaneous coronary angioplasty only with kissing drug-coated balloons as a treatment strategy in a young woman with active systemic lupus erythematosus and cardiogenic shock after coronary artery bypass grafting.","authors":"Mikołaj Derewońko, Filip Waśniewski, Magdalena Dudek, Agnieszka Bartczak-Rutkowska, Maciej Lesiak, Marta Kałużna-Oleksy","doi":"10.20452/pamw.16901","DOIUrl":"10.20452/pamw.16901","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of lipoprotein(a) in atrial fibrillation: a systematic review.","authors":"Grzegorz Procyk, Marcin Grabowski, Aleksandra Gąsecka","doi":"10.20452/pamw.16924","DOIUrl":"10.20452/pamw.16924","url":null,"abstract":"<p><strong>Introduction: </strong>Atrial fibrillation (AF) is the most prevalent form of cardiac arrhythmia worldwide. Early diagnosis and treatment are essential, emphasizing the need to develop novel biomarkers. Lipoprotein(a) (Lp[a]) has recently been widely investigated as a potential risk factor for various cardiovascular conditions, including AF.</p><p><strong>Objectives: </strong>Our objective was to systematically review the current knowledge on the role of Lp(a) in AF.</p><p><strong>Methods: </strong>This systematic review adhered to the PRISMA 2020 guidelines. We included full‑text original clinical studies in English assessing the role of Lp(a) in AF. A comprehensive search in 5 databases: Embase, MEDLINE Ultimate, PubMed, Scopus, and Web of Science yielded 26 original, relevant clinical research articles that we analyzed in this study.</p><p><strong>Results: </strong>Studies investigating the association between Lp(a) level and the incidence of AF present conflicting findings. However, Mendelian randomization studies advocate a causal association between high Lp(a) levels and AF. Research data suggest that AF patients who experience stroke or other thromboembolic events tend to have higher Lp(a) levels than those not experiencing such events.</p><p><strong>Conclusions: </strong>Existing data suggest Lp(a) may play a pathophysiological role in AF patients, especially those who experience thromboembolic events. Nevertheless, this field requires further research due to inconsistencies in the existing evidence.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}