Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine最新文献

{"title":"Covered stent implantation for hepatic artery stenosis following liver transplantation.","authors":"Mateusz Malina, Artur Milnerowicz, Aleksandra Milnerowicz, Adrian Doroszko, Waldemar Banasiak, Krzysztof Ściborski","doi":"10.20452/pamw.17353","DOIUrl":"https://doi.org/10.20452/pamw.17353","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"136 9","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunometabolic activation of neutrophils is associated with circulating tissue factor-positive microparticle profile in gestational diabetes mellitus.","authors":"Katarzyna Gawlik, Dorota Pawlica-Gosiewska, Tomasz Milewicz, Bogdan Solnica","doi":"10.20452/pamw.17345","DOIUrl":"10.20452/pamw.17345","url":null,"abstract":"<p><strong>Introduction: </strong>Gestational diabetes mellitus (GDM) is associated with chronic low‑grade inflammation and an increased risk of thromboembolic complications. Tissue factor-positive microparticles (TF⁺MPs) link inflammatory and coagulation pathways, but their cellular origin and immunometabolic determinants in GDM remain unclear.</p><p><strong>Objectives: </strong>To characterize neutrophil-, monocyte-, and endothelium‑derived TF⁺MPs in GDM and to assess their relationships with metabolic and inflammatory markers.</p><p><strong>Patients and methods: </strong>We studied 70 women with GDM and 55 healthy pregnant controls at 28-33 weeks' gestation. Neutrophil‑derived (TF⁺CD66b⁺), monocyte‑derived (TF⁺CD14⁺), and endothelium‑derived (TF⁺CD144⁺)  MPs were quantified by flow cytometry. Levels of glycated hemoglobin (HbA_1c) and interleukin‑18 (IL‑18) were measured as markers of glycemic exposure and inflammatory response, respectively. Statistical analyses included the Mann-Whitney test, Cliff delta (δ), correlation analysis, and receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>The women with GDM exhibited significantly higher counts of TF⁺CD66b⁺ MPs than the controls (δ = 0.71; <i>P</i> <0.001). The percentage of TF⁺CD66b⁺ MPs relative to the total TF⁺MP count showed marked separation between the groups (area under the curve, 0.905). The TF⁺CD14⁺ MP count was increased in GDM (δ = 0.34; <i>P</i> = 0.001), whereas the TF⁺CD144⁺ MP count did not differ between the groups (δ = 0.11; <i>P</i> = 0.29). The TF⁺CD66b⁺ MP count correlated positively with HbA_1c (<i>R</i> = 0.56; <i>P</i> <0.001) and IL‑18 (<i>R</i> = 0.34; <i>P</i> = 0.004) levels, with no significant associations observed for maternal body mass index, fasting glucose level, or glucose‑lowering therapy.</p><p><strong>Conclusions: </strong>GDM was associated with marked enrichment of TF⁺CD66b⁺ MPs, reflecting immunometabolic neutrophil activation rather than obesity‑related effects. These findings identify TF⁺CD66b⁺ MPs as a downstream marker linking metabolic and inflammatory pathways in GDM.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148413530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An atypical presentation of retroperitoneal fibrosis as an adrenal mass: diagnostic challenges.","authors":"Katarzyna Zięba, Jerzy Chudek, Marek Syguda, Jacek Pająk, Robert Król","doi":"10.20452/pamw.17342","DOIUrl":"10.20452/pamw.17342","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148399887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Corynebacterium diphtheriae</i> as a very rare cause of infective endocarditis.","authors":"Dominika Wójcicka, Magdalena Kasińska, Zuzanna Katulska, Andrzej Chciałowski, Magdalena Potapowicz-Krysztofiak, Aneta Guzek","doi":"10.20452/pamw.17348","DOIUrl":"10.20452/pamw.17348","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occurrence of de novo hepatocellular carcinoma after successful direct-acting antiviral therapy in patients without cirrhosis.","authors":"Dorota Zarębska-Michaluk, Robert Flisiak, Kinga Brzdęk, Krystyna Dobrowolska, Jakub Janczura, Michał Brzdęk","doi":"10.20452/pamw.17381","DOIUrl":"https://doi.org/10.20452/pamw.17381","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":"136 9","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An ileal neuroendocrine tumor with pancreatic metastasis: diagnostic reassessment after more than 10 years.","authors":"Bartosz Basiaga, Agnieszka Niewiadomska, Beata Kos-Kudła, Violetta Rosiek","doi":"10.20452/pamw.17401","DOIUrl":"https://doi.org/10.20452/pamw.17401","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mystery of membranous nephropathy: from presumed primary to secondary following detection of an underlying malignancy.","authors":"Iwona Filipska, Marta Ruskań-Bakun, Agnieszka Perkowska-Ptasińska, Tomasz Stompór","doi":"10.20452/pamw.17410","DOIUrl":"https://doi.org/10.20452/pamw.17410","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When diabetes meets mucor: invasive pulmonary mucormycosis in a young patient.","authors":"Małgorzata Barnaś, Monika Zielińska-Krawczyk, Rafał Krenke","doi":"10.20452/pamw.17407","DOIUrl":"https://doi.org/10.20452/pamw.17407","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe complement-mediated thrombotic microangiopathy in systemic lupus erythematosus treated with ravulizumab: therapeutic challenges.","authors":"Ksymena Leśniak, Magdalena Mosakowska, Mateusz Nowak, Karolina Mruk, Stanisław Niemczyk","doi":"10.20452/pamw.17408","DOIUrl":"https://doi.org/10.20452/pamw.17408","url":null,"abstract":"","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence in nephrology: recent advances.","authors":"Ziad M Zoghby","doi":"10.20452/pamw.17409","DOIUrl":"https://doi.org/10.20452/pamw.17409","url":null,"abstract":"<p><p>Artificial intelligence (AI) is moving rapidly from experimental prediction models toward workflow-integrated tools that can support clinical care, education, research, and operational efficiency. Kidney care is particularly well suited to AI because it is data-rich, longitudinal, and multidisciplinary, incorporating laboratory trajectories, medications, imaging, pathology, dialysis machine data, transplant immunology, wearable sensors, and unstructured clinical notes. Recent advances include electronic health record-based models for acute kidney injury prediction, machine-learning approaches for chronic kidney disease progression and diabetic kidney disease risk stratification, automated measurement of total kidney volume in autosomal dominant polycystic kidney disease, quantitative renal pathology, intradialytic event prediction, transplant allograft risk models, AI-enhanced electrocardiography for electrolyte and hypertension-related applications, and large language models for documentation, summarization, patient education, and clinical decision support. However, high discrimination in retrospective datasets has not consistently translated into improved outcomes after clinical deployment. Evidence from AKI alert trials emphasizes that AI must be coupled to actionable workflows, clinician oversight, calibration, and monitoring for bias, safety, and alert burden. Generative AI offers a compelling opportunity to reduce administrative work and restore clinician time, but hallucination, incomplete guideline concordance, and variable safety remain barriers. The next phase of AI in nephrology should prioritize pragmatic validation, transparent governance, human-AI collaboration, and practical applications that improve patient-centered kidney outcomes rather than technology adoption for its own sake.</p>","PeriodicalId":49680,"journal":{"name":"Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}