Reviews in the Neurosciences最新文献

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3区 医学
Reviews in the Neurosciences Pub Date : 2023-10-01 DOI: 10.1515/revneuro-2023-frontmatter7
{"title":"Frontmatter","authors":"","doi":"10.1515/revneuro-2023-frontmatter7","DOIUrl":"https://doi.org/10.1515/revneuro-2023-frontmatter7","url":null,"abstract":"","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134936096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding visual processing of motion: completing the picture using experimentally driven computational models of MT. 理解运动的视觉处理:使用实验驱动的MT计算模型完成图片。
IF 3.4 3区 医学
Reviews in the Neurosciences Pub Date : 2023-09-20 Print Date: 2024-04-25 DOI: 10.1515/revneuro-2023-0052
Parvin Zarei Eskikand, David B Grayden, Tatiana Kameneva, Anthony N Burkitt, Michael R Ibbotson
{"title":"Understanding visual processing of motion: completing the picture using experimentally driven computational models of MT.","authors":"Parvin Zarei Eskikand, David B Grayden, Tatiana Kameneva, Anthony N Burkitt, Michael R Ibbotson","doi":"10.1515/revneuro-2023-0052","DOIUrl":"10.1515/revneuro-2023-0052","url":null,"abstract":"<p><p>Computational modeling helps neuroscientists to integrate and explain experimental data obtained through neurophysiological and anatomical studies, thus providing a mechanism by which we can better understand and predict the principles of neural computation. Computational modeling of the neuronal pathways of the visual cortex has been successful in developing theories of biological motion processing. This review describes a range of computational models that have been inspired by neurophysiological experiments. Theories of local motion integration and pattern motion processing are presented, together with suggested neurophysiological experiments designed to test those hypotheses.</p>","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":" ","pages":"243-258"},"PeriodicalIF":3.4,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41168062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated diagnosis of autism with artificial intelligence: State of the art. 人工智能自动诊断自闭症:最新技术。
IF 3.4 3区 医学
Reviews in the Neurosciences Pub Date : 2023-09-08 Print Date: 2024-02-26 DOI: 10.1515/revneuro-2023-0050
Amir Valizadeh, Mana Moassefi, Amin Nakhostin-Ansari, Soheil Heidari Some'eh, Hossein Hosseini-Asl, Mehrnush Saghab Torbati, Reyhaneh Aghajani, Zahra Maleki Ghorbani, Iman Menbari-Oskouie, Faezeh Aghajani, Alireza Mirzamohamadi, Mohammad Ghafouri, Shahriar Faghani, Amir Hossein Memari
{"title":"Automated diagnosis of autism with artificial intelligence: State of the art.","authors":"Amir Valizadeh, Mana Moassefi, Amin Nakhostin-Ansari, Soheil Heidari Some'eh, Hossein Hosseini-Asl, Mehrnush Saghab Torbati, Reyhaneh Aghajani, Zahra Maleki Ghorbani, Iman Menbari-Oskouie, Faezeh Aghajani, Alireza Mirzamohamadi, Mohammad Ghafouri, Shahriar Faghani, Amir Hossein Memari","doi":"10.1515/revneuro-2023-0050","DOIUrl":"10.1515/revneuro-2023-0050","url":null,"abstract":"<p><p>Autism spectrum disorder (ASD) represents a panel of conditions that begin during the developmental period and result in impairments of personal, social, academic, or occupational functioning. Early diagnosis is directly related to a better prognosis. Unfortunately, the diagnosis of ASD requires a long and exhausting subjective process. We aimed to review the state of the art for automated autism diagnosis and recognition in this research. In February 2022, we searched multiple databases and sources of gray literature for eligible studies. We used an adapted version of the QUADAS-2 tool to assess the risk of bias in the studies. A brief report of the methods and results of each study is presented. Data were synthesized for each modality separately using the Split Component Synthesis (SCS) method. We assessed heterogeneity using the <i>I</i> <sup>2</sup> statistics and evaluated publication bias using trim and fill tests combined with ln DOR. Confidence in cumulative evidence was assessed using the GRADE approach for diagnostic studies. We included 344 studies from 186,020 participants (51,129 are estimated to be unique) for nine different modalities in this review, from which 232 reported sufficient data for meta-analysis. The area under the curve was in the range of 0.71-0.90 for all the modalities. The studies on EEG data provided the best accuracy, with the area under the curve ranging between 0.85 and 0.93. We found that the literature is rife with bias and methodological/reporting flaws. Recommendations are provided for future research to provide better studies and fill in the current knowledge gaps.</p>","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":" ","pages":"141-163"},"PeriodicalIF":3.4,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10552799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Brain-breath" interactions: respiration-timing-dependent impact on functional brain networks and beyond. "大脑与呼吸 "之间的相互作用:呼吸计时对大脑功能网络及其他方面的影响。
IF 3.4 3区 医学
Reviews in the Neurosciences Pub Date : 2023-09-01 Print Date: 2024-02-26 DOI: 10.1515/revneuro-2023-0062
Nozomu H Nakamura, Yoshitaka Oku, Masaki Fukunaga
{"title":"\"Brain-breath\" interactions: respiration-timing-dependent impact on functional brain networks and beyond.","authors":"Nozomu H Nakamura, Yoshitaka Oku, Masaki Fukunaga","doi":"10.1515/revneuro-2023-0062","DOIUrl":"10.1515/revneuro-2023-0062","url":null,"abstract":"<p><p>Breathing is a natural daily action that one cannot do without, and it sensitively and intensely changes under various situations. What if this essential act of breathing can impact our overall well-being? Recent studies have demonstrated that breathing oscillations couple with higher brain functions, i.e., perception, motor actions, and cognition. Moreover, the timing of breathing, a phase transition from exhalation to inhalation, modulates specific cortical activity and accuracy in cognitive tasks. To determine possible respiratory roles in attentional and memory processes and functional neural networks, we discussed how breathing interacts with the brain that are measured by electrophysiology and functional neuroimaging: (i) respiration-dependent modulation of mental health and cognition; (ii) respiratory rhythm generation and respiratory pontomedullary networks in the brainstem; (iii) respiration-dependent effects on specific brainstem regions and functional neural networks (e.g., glutamatergic PreBötzinger complex neurons, GABAergic parafacial neurons, adrenergic C1 neurons, parabrachial nucleus, locus coeruleus, temporoparietal junction, default-mode network, ventral attention network, and cingulo-opercular salience network); and (iv) a potential application of breathing manipulation in mental health care. These outlines and considerations of \"brain-breath\" interactions lead to a better understanding of the interoceptive and cognitive mechanisms that underlie brain-body interactions in health conditions and in stress-related and neuropsychiatric disorders.</p>","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":" ","pages":"165-182"},"PeriodicalIF":3.4,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10184701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vivo C6 glioma models: an update and a guide toward a more effective preclinical evaluation of potential anti-glioblastoma drugs. 体内C6胶质瘤模型:更新并指导对潜在抗胶质母细胞瘤药物进行更有效的临床前评估。
IF 3.4 3区 医学
Reviews in the Neurosciences Pub Date : 2023-09-01 Print Date: 2024-02-26 DOI: 10.1515/revneuro-2023-0067
Safura Pournajaf, Nastaran Afsordeh, Mohammad Hossein Pourgholami
{"title":"<i>In vivo</i> C6 glioma models: an update and a guide toward a more effective preclinical evaluation of potential anti-glioblastoma drugs.","authors":"Safura Pournajaf, Nastaran Afsordeh, Mohammad Hossein Pourgholami","doi":"10.1515/revneuro-2023-0067","DOIUrl":"10.1515/revneuro-2023-0067","url":null,"abstract":"<p><p>Glioblastoma multiform (GBM) is the most common primary brain tumor with a poor prognosis and few therapeutic choices. <i>In vivo,</i> tumor models are useful for enhancing knowledge of underlying GBM pathology and developing more effective therapies/agents at the preclinical level, as they recapitulate human brain tumors. The C6 glioma cell line has been one of the most widely used cell lines in neuro-oncology research as they produce tumors that share the most similarities with human GBM regarding genetic, invasion, and expansion profiles and characteristics. This review provides an overview of the distinctive features and the different animal models produced by the C6 cell line. We also highlight specific applications of various C6 <i>in vivo</i> models according to the purpose of the study and offer some technical notes for more convenient/repeatable modeling. This work also includes novel findings discovered in our laboratory, which would further enhance the feasibility of the model in preclinical GBM investigations.</p>","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":" ","pages":"183-195"},"PeriodicalIF":3.4,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10483301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An update to pain management after spinal cord injury: from pharmacology to circRNAs. 脊髓损伤后疼痛管理的最新进展:从药理学到环状rna。
IF 4.1 3区 医学
Reviews in the Neurosciences Pub Date : 2023-08-28 DOI: 10.1515/revneuro-2022-0089
Graciela L Mazzone, María F Coronel, Miranda Mladinic, Cynthia Sámano
{"title":"An update to pain management after spinal cord injury: from pharmacology to circRNAs.","authors":"Graciela L Mazzone,&nbsp;María F Coronel,&nbsp;Miranda Mladinic,&nbsp;Cynthia Sámano","doi":"10.1515/revneuro-2022-0089","DOIUrl":"https://doi.org/10.1515/revneuro-2022-0089","url":null,"abstract":"<p><p>Neuropathic pain (NP) following a spinal cord injury (SCI) is often hard to control and therapies should be focused on the physical, psychological, behavioral, social, and environmental factors that may contribute to chronic sensory symptoms. Novel therapeutic treatments for NP management should be based on the combination of pharmacological and nonpharmacological options. Some of them are addressed in this review with a focus on mechanisms and novel treatments. Several reports demonstrated an aberrant expression of non-coding RNAs (ncRNAs) that may represent key regulatory factors with a crucial role in the pathophysiology of NP and as potential diagnostic biomarkers. This review analyses the latest evidence for cellular and molecular mechanisms associated with the role of circular RNAs (circRNAs) in the management of pain after SCI. Advantages in the use of circRNA are their stability (up to 48 h), and specificity as sponges of different miRNAs related to SCI and nerve injury. The present review discusses novel data about deregulated circRNAs (up or downregulated) that sponge miRNAs, and promote cellular and molecular interactions with mRNAs and proteins. This data support the concept that circRNAs could be considered as novel potential therapeutic targets for NP management especially after spinal cord injuries.</p>","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":"34 6","pages":"599-611"},"PeriodicalIF":4.1,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10304856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of the application of three-dimensional convolutional neural networks for the diagnosis of Alzheimer's disease using neuroimaging. 三维卷积神经网络在阿尔茨海默病神经影像学诊断中的应用综述。
IF 4.1 3区 医学
Reviews in the Neurosciences Pub Date : 2023-08-28 DOI: 10.1515/revneuro-2022-0122
Xinze Xu, Lan Lin, Shen Sun, Shuicai Wu
{"title":"A review of the application of three-dimensional convolutional neural networks for the diagnosis of Alzheimer's disease using neuroimaging.","authors":"Xinze Xu,&nbsp;Lan Lin,&nbsp;Shen Sun,&nbsp;Shuicai Wu","doi":"10.1515/revneuro-2022-0122","DOIUrl":"https://doi.org/10.1515/revneuro-2022-0122","url":null,"abstract":"<p><p>Alzheimer's disease (AD) is a degenerative disorder that leads to progressive, irreversible cognitive decline. To obtain an accurate and timely diagnosis and detect AD at an early stage, numerous approaches based on convolutional neural networks (CNNs) using neuroimaging data have been proposed. Because 3D CNNs can extract more spatial discrimination information than 2D CNNs, they have emerged as a promising research direction in the diagnosis of AD. The aim of this article is to present the current state of the art in the diagnosis of AD using 3D CNN models and neuroimaging modalities, focusing on the 3D CNN architectures and classification methods used, and to highlight potential future research topics. To give the reader a better overview of the content mentioned in this review, we briefly introduce the commonly used imaging datasets and the fundamentals of CNN architectures. Then we carefully analyzed the existing studies on AD diagnosis, which are divided into two levels according to their inputs: 3D subject-level CNNs and 3D patch-level CNNs, highlighting their contributions and significance in the field. In addition, this review discusses the key findings and challenges from the studies and highlights the lessons learned as a roadmap for future research. Finally, we summarize the paper by presenting some major findings, identifying open research challenges, and pointing out future research directions.</p>","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":"34 6","pages":"649-670"},"PeriodicalIF":4.1,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10286785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Microbiota-gut-brain axis and related therapeutics in Alzheimer's disease: prospects for multitherapy and inflammation control. 阿尔茨海默病的微生物-肠-脑轴和相关治疗:综合治疗和炎症控制的前景。
IF 4.1 3区 医学
Reviews in the Neurosciences Pub Date : 2023-08-28 DOI: 10.1515/revneuro-2023-0006
Jiahao Li, Feng Zhang, Li Zhao, Chunbo Dong
{"title":"Microbiota-gut-brain axis and related therapeutics in Alzheimer's disease: prospects for multitherapy and inflammation control.","authors":"Jiahao Li,&nbsp;Feng Zhang,&nbsp;Li Zhao,&nbsp;Chunbo Dong","doi":"10.1515/revneuro-2023-0006","DOIUrl":"https://doi.org/10.1515/revneuro-2023-0006","url":null,"abstract":"<p><p>Alzheimer's disease (AD) is the most common type of dementia in the elderly and causes neurodegeneration, leading to memory loss, behavioral disorder, and psychiatric impairment. One potential mechanism contributing to the pathogenesis of AD may be the imbalance in gut microbiota, local and systemic inflammation, and dysregulation of the microbiota-gut-brain axis (MGBA). Most of the AD drugs approved for clinical use today are symptomatic treatments that do not improve AD pathologic changes. As a result, researchers are exploring novel therapeutic modalities. Treatments involving the MGBA include antibiotics, probiotics, transplantation of fecal microbiota, botanical products, and others. However, single-treatment modalities are not as effective as expected, and a combination therapy is gaining momentum. The purpose of this review is to summarize recent advances in MGBA-related pathological mechanisms and treatment modalities in AD and to propose a new concept of combination therapy. \"MGBA-based multitherapy\" is an emerging view of treatment in which classic symptomatic treatments and MGBA-based therapeutic modalities are used in combination. Donepezil and memantine are two commonly used drugs in AD treatment. On the basis of the single/combined use of these two drugs, two/more additional drugs and treatment modalities that target the MGBA are chosen based on the characteristics of the patient's condition as an adjuvant treatment, as well as the maintenance of good lifestyle habits. \"MGBA-based multitherapy\" offers new insights for the treatment of cognitive impairment in AD patients and is expected to show good therapeutic results.</p>","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":"34 6","pages":"695-718"},"PeriodicalIF":4.1,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9984548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current advances in stem cell therapy in the treatment of multiple sclerosis. 干细胞治疗多发性硬化的最新进展。
IF 4.1 3区 医学
Reviews in the Neurosciences Pub Date : 2023-08-28 DOI: 10.1515/revneuro-2022-0102
Parnian Zolfaghari Baghbadorani, Amirmasoud Rayati Damavandi, Samira Moradi, Meysam Ahmadi, Peyman Bemani, Hamid Aria, Hossein Mottedayyen, Amirhossein Rayati Damavandi, Nahid Eskandari, Farshid Fathi
{"title":"Current advances in stem cell therapy in the treatment of multiple sclerosis.","authors":"Parnian Zolfaghari Baghbadorani,&nbsp;Amirmasoud Rayati Damavandi,&nbsp;Samira Moradi,&nbsp;Meysam Ahmadi,&nbsp;Peyman Bemani,&nbsp;Hamid Aria,&nbsp;Hossein Mottedayyen,&nbsp;Amirhossein Rayati Damavandi,&nbsp;Nahid Eskandari,&nbsp;Farshid Fathi","doi":"10.1515/revneuro-2022-0102","DOIUrl":"https://doi.org/10.1515/revneuro-2022-0102","url":null,"abstract":"<p><p>Multiple sclerosis (MS) is an inflammatory disease related to the central nervous system (CNS) with a significant global burden. In this illness, the immune system plays an essential role in its pathophysiology and progression. The currently available treatments are not recognized as curable options and, at best, might slow the progression of MS injuries to the CNS. However, stem cell treatment has provided a new avenue for treating MS. Stem cells may enhance CNS healing and regulate immunological responses. Likewise, stem cells can come from various sources, including adipose, neuronal, bone marrow, and embryonic tissues. Choosing the optimal cell source for stem cell therapy is still a difficult verdict. A type of stem cell known as mesenchymal stem cells (MSCs) is obtainable from different sources and has a strong immunomodulatory impact on the immune system. According to mounting data, the umbilical cord and adipose tissue may serve as appropriate sources for the isolation of MSCs. Human amniotic epithelial cells (hAECs), as novel stem cell sources with immune-regulatory effects, regenerative properties, and decreased antigenicity, can also be thought of as a new upcoming contender for MS treatment. Overall, the administration of stem cells in different sets of animal and clinical trials has shown immunomodulatory and neuroprotective results. Therefore, this review aims to discuss the different types of stem cells by focusing on MSCs and their mechanisms, which can be used to treat and improve the outcomes of MS disease.</p>","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":"34 6","pages":"613-633"},"PeriodicalIF":4.1,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9926122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A systematic review of the effects of transcranial photobiomodulation on brain activity in humans. 经颅光生物调节对人类大脑活动影响的系统综述。
IF 4.1 3区 医学
Reviews in the Neurosciences Pub Date : 2023-08-28 DOI: 10.1515/revneuro-2023-0003
Marjorie Dole, Vincent Auboiroux, Lilia Langar, John Mitrofanis
{"title":"A systematic review of the effects of transcranial photobiomodulation on brain activity in humans.","authors":"Marjorie Dole,&nbsp;Vincent Auboiroux,&nbsp;Lilia Langar,&nbsp;John Mitrofanis","doi":"10.1515/revneuro-2023-0003","DOIUrl":"https://doi.org/10.1515/revneuro-2023-0003","url":null,"abstract":"<p><p>In recent years, transcranial photobiomodulation (tPBM) has been developing as a promising method to protect and repair brain tissues against damages. The aim of our systematic review is to examine the results available in the literature concerning the efficacy of tPBM in changing brain activity in humans, either in healthy individuals, or in patients with neurological diseases. Four databases were screened for references containing terms encompassing photobiomodulation, brain activity, brain imaging, and human. We also analysed the quality of the included studies using validated tools. Results in healthy subjects showed that even after a single session, tPBM can be effective in influencing brain activity. In particular, the different transcranial approaches - using a focal stimulation or helmet for global brain stimulation - seemed to act at both the vascular level by increasing regional cerebral blood flow (rCBF) and at the neural level by changing the activity of the neurons. In addition, studies also showed that even a focal stimulation was sufficient to induce a global change in functional connectivity across brain networks. Results in patients with neurological disease were sparser; nevertheless, they indicated that tPBM could improve rCBF and functional connectivity in several regions. Our systematic review also highlighted the heterogeneity in the methods and results generated, together with the need for more randomised controlled trials in patients with neurological diseases. In summary, tPBM could be a promising method to act on brain function, but more consistency is needed in order appreciate fully the underlying mechanisms and the precise outcomes.</p>","PeriodicalId":49623,"journal":{"name":"Reviews in the Neurosciences","volume":"34 6","pages":"671-693"},"PeriodicalIF":4.1,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9930003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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