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Correction: Green and sustainable LC‑APCI‑MS/MS method for simultaneous quantification of genotoxic nitrosamines in antidiabetic medication: sitagliptin. 校正:绿色可持续LC - APCI - MS/MS同时定量抗糖尿病药物西格列汀中遗传毒性亚硝胺的方法。
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-27 DOI: 10.1186/s13065-025-01563-6
Sriram Pepakayala, Venkata Nadh Ratnakaram, Yuvaraj Zunjarrao, Yogesh Kumar Lohia
{"title":"Correction: Green and sustainable LC‑APCI‑MS/MS method for simultaneous quantification of genotoxic nitrosamines in antidiabetic medication: sitagliptin.","authors":"Sriram Pepakayala, Venkata Nadh Ratnakaram, Yuvaraj Zunjarrao, Yogesh Kumar Lohia","doi":"10.1186/s13065-025-01563-6","DOIUrl":"10.1186/s13065-025-01563-6","url":null,"abstract":"","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"176"},"PeriodicalIF":4.3,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144511387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stability indicating green micellar liquid chromatographic method for simultaneous analysis of Metformin and dapagliflozin in their tablets. 稳定性指示绿色胶束液相色谱法同时分析二甲双胍和达格列净片剂中的含量。
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-21 DOI: 10.1186/s13065-025-01537-8
Aya A Marie, Mohamed G Yassin, Aya Roshdy
{"title":"Stability indicating green micellar liquid chromatographic method for simultaneous analysis of Metformin and dapagliflozin in their tablets.","authors":"Aya A Marie, Mohamed G Yassin, Aya Roshdy","doi":"10.1186/s13065-025-01537-8","DOIUrl":"10.1186/s13065-025-01537-8","url":null,"abstract":"<p><p>A green micellar liquid chromatography (MLC) technique was established for simultaneous determination of dapagliflozin (DAP) and Metformin HCl (MET) in their pure and tablet dosage forms. Stability studies were carried out for both drugs using different five degradation conditions. The chromatographic separation was achieved using BDS Thermo-Hypersil C8 (150 mm x 4.6 mm, 5 μm) column and hybrid micellar mobile phase composed of 50 gm of sodium lauryl sulphate in 500 mL purified water with 100mL of 2-Propanol and 3 mL triethylamine and then completed with purified water to 1000mL, and the mobile phase pH was 3.3. The (PDA) detector was used at 223 nm, 40 °C column temperature, 1mL/min flow rate and 20µL injection volume. The retention times of DAP and MET were (5.37 ± 0.4 min) and (7.64 ± 0.2 min), respectively. Linearity was constructed in ranges of (0.2-7 µg/mL) for DAP and (50-700 µg/mL) for MET. Mean percentage recoveries of DAP and MET were 99.88%±0.53 and 100.034%±0.60, respectively indicates good accuracy. The developed approach was validated according to ICH guidelines and efficiently applied for the analysis of DAP and MET in Dexigloflozin plus<sup>®</sup> 5/500 tablets. For the greenness assessment the analytical eco-scale, Complex MoGAPI and AGREE methods were applied.</p>","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"175"},"PeriodicalIF":4.3,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2D CuO/rGO nanocomposite: a novel architecture for enhanced Cr(VI) photo-reduction. 二维CuO/rGO纳米复合材料:一种增强Cr(VI)光还原的新结构。
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-19 DOI: 10.1186/s13065-025-01482-6
Islam Gomaa, Ahmed Helal, Medhat A Ibrahim, Nasser Mohammed Hosny
{"title":"2D CuO/rGO nanocomposite: a novel architecture for enhanced Cr(VI) photo-reduction.","authors":"Islam Gomaa, Ahmed Helal, Medhat A Ibrahim, Nasser Mohammed Hosny","doi":"10.1186/s13065-025-01482-6","DOIUrl":"10.1186/s13065-025-01482-6","url":null,"abstract":"<p><p>The urgent need for efficient detoxification of carcinogenic hexavalent chromium (Cr(VI)) in aquatic environments has driven the development of advanced photocatalytic materials. This study presents the synthesis of 2D CuO/reduced graphene oxide (rGO) nanocomposite via probe sonication, designed to synergistically enhance the photocatalytic reduction of Cr(VI) to less toxic Cr(III). The nanocomposite was meticulously characterized using XRD, HRTEM, FESEM, XPS, and UV-Vis diffuse reflectance spectroscopy. Structural analysis confirmed the formation of CuO nanosheets (average size: 396 nm, thickness: 6 nm) integrated with rGO, where the rGO acted as an electron acceptor, mitigating charge recombination. XPS revealed Cu²⁺ in CuO and Cu(OH)₂ phases, while FTIR confirmed interfacial interactions between CuO and rGO via oxygen functional groups. The CuO/rGO composite exhibited a reduced bandgap (1.35 eV → lower with rGO incorporation) and broad visible-light absorption, critical for photocatalytic activity. Under visible light, the composite achieved a remarkable 75% Cr(VI) reduction efficiency within 180 min triple that of pure CuO (25%) with a rate constant (0.007 min⁻¹) sevenfold higher. This enhancement is attributed to rGO role in facilitating electron transfer from CuO conduction band to its LUMO, minimizing electron-hole recombination. The composite demonstrated excellent recyclability over three cycles without significant efficiency loss. These findings underscore the potential of CuO/rGO as a robust, sustainable photocatalyst for environmental.</p>","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"174"},"PeriodicalIF":4.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparation, characterization and in vitro evaluation of phosphate-doped bioactive glass nanoparticles as promising candidates for therapeutic applications. 磷酸盐掺杂生物活性玻璃纳米粒子的制备、表征和体外评价作为治疗应用的有前途的候选者。
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-19 DOI: 10.1186/s13065-025-01543-w
Wael M Aboulthana, Sahar M Mousa, Gehan T El-Bassyouni, Esmat M A Hamzawy, Amal G Hussien, M Eltohamy
{"title":"Preparation, characterization and in vitro evaluation of phosphate-doped bioactive glass nanoparticles as promising candidates for therapeutic applications.","authors":"Wael M Aboulthana, Sahar M Mousa, Gehan T El-Bassyouni, Esmat M A Hamzawy, Amal G Hussien, M Eltohamy","doi":"10.1186/s13065-025-01543-w","DOIUrl":"10.1186/s13065-025-01543-w","url":null,"abstract":"<p><p>This research focuses on synthesizing bioactive glass nanoparticles with different phosphate concentrations to evaluate their physicochemical characteristics and explore their biomedical potential. The nanoparticles were fabricated by melting a mixture of silica, calcium oxide, sodium oxide, and ammonium dihydrogen phosphate at 1450 °C, followed by ball milling to obtain the optimal particle size distribution. The study systematically investigated the effect of phosphate content on the nanoparticles' structural properties and bioactive performance. Advanced characterization methods; such as XRD, FTIR, DTA, and FE-SEM-EDX were used to examine structural stability and phosphate-induced surface alterations. In vitro assays revealed dose-dependent antioxidant, anti-diabetic, anti-Alzheimer's, anti-arthritic, and anti-inflammatory activities, with higher phosphate content enhancing bioactivity. Results demonstrated enhanced radical scavenging and enzyme inhibition in samples with higher phosphate levels. These findings suggest that phosphate-doped bioactive glass nanoparticles hold significant promise for therapeutic applications. The research advances the understanding of how synthesis parameters influence bioactivity, providing valuable insights for designing next-generation biomedical materials.</p>","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"170"},"PeriodicalIF":4.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutting edge for technical textiles (fluorescent, antibacterial and UV-protective) by incroporation of thienoisoquinoline-quinazoline derivatives. 通过添加噻吩异喹啉-喹唑啉衍生物,在技术纺织品(荧光,抗菌和防紫外线)方面处于领先地位。
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-19 DOI: 10.1186/s13065-025-01504-3
Walid Sharmoukh, Islam S Marae, Etify A Bakhite, Hanan B Ahmed, Hossam E Emam
{"title":"Cutting edge for technical textiles (fluorescent, antibacterial and UV-protective) by incroporation of thienoisoquinoline-quinazoline derivatives.","authors":"Walid Sharmoukh, Islam S Marae, Etify A Bakhite, Hanan B Ahmed, Hossam E Emam","doi":"10.1186/s13065-025-01504-3","DOIUrl":"10.1186/s13065-025-01504-3","url":null,"abstract":"<p><p>Nowadays design of multi-functionalized textiles as technical textiles is highly demanded to be applied in different environments and under hard weather condition. Herein, tri-functionalized (fluorescent, antimicrobial and UV-protection) cotton textiles were designed by immobilization of heterocyclic compounds based on quinazoline derivatives (QDs). Firstly, four quinazoline derivatives (QD-1 = H, QD-2 = O-CH<sub>3</sub>, QD-3 = Cl, QD-4 = H [without COOH]) were synthesized for the first time starting from 2-(chloromethyl) quinazoline-4(3H)-one. The chemical structure of all obtained QDs were investigated by NMR (<sup>1</sup>H & <sup>13</sup>C) and infrared spectroscopy, in addition to the measurement of melting points, yields and emission spectra. Secondly, the synthesized QDs were immobilized within cotton textile, while cotton was per-activated by interaction with cationic reagent. The modified textiles (QDs@Q-cotton) gained dark yellow color. The QDs@Q-cotton emitted greenish radiation and showed intense emission fluorescence at 485-521 nm. Good-very good (UPF = 23.6-32.8) and good (21.3-25.8) UV protection was respectively shown for QDs@Q-cotton before and after 10 washings. The protection from UV radiation for QDs@Q-cotton is attributed to the reflection of UV radiation by effect of QDs micro particles which deposited within the cotton matrix. The modified textiles exhibited antimicrobial action against S. aureus and E. coli bacteria, while the mortality was 79.9-89.1% and 69.7-76.2% before and after 10 washings, respectively. The antibacterial activity of the QDs@Q-cotton fabrics is attributed to the QDs skeleton. The highest antibacterial action for QD-3@Q-cotton is related to the chlorine derivative. The multi-functionalized textile with good durability could be successfully employed in the military/soldiers clothes.</p>","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"173"},"PeriodicalIF":4.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solid-contact ion-selective electrode for the determination of silver ions released from silver sulfadiazine in sodium hyaluronate formulations: evaluation of whiteness and greenness profiles. 固体接触离子选择电极测定透明质酸钠配方中磺胺嘧啶银释放的银离子:白度和绿度轮廓的评价。
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-19 DOI: 10.1186/s13065-025-01546-7
Manal Ibrahim, Nesrin K Ramadan, Magda M Ibrahim, Shereen A Boltia
{"title":"Solid-contact ion-selective electrode for the determination of silver ions released from silver sulfadiazine in sodium hyaluronate formulations: evaluation of whiteness and greenness profiles.","authors":"Manal Ibrahim, Nesrin K Ramadan, Magda M Ibrahim, Shereen A Boltia","doi":"10.1186/s13065-025-01546-7","DOIUrl":"10.1186/s13065-025-01546-7","url":null,"abstract":"","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"167"},"PeriodicalIF":4.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green-engineered multispectral analytical approaches for simultaneous quantification of amoxicillin and diclofenac in pure and combined forms. 同时定量测定阿莫西林和双氯芬酸纯和联合形式的绿色工程多光谱分析方法。
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-19 DOI: 10.1186/s13065-025-01545-8
Neamat T Barakat, Amina M El-Brashy, Mona E Fathy
{"title":"Green-engineered multispectral analytical approaches for simultaneous quantification of amoxicillin and diclofenac in pure and combined forms.","authors":"Neamat T Barakat, Amina M El-Brashy, Mona E Fathy","doi":"10.1186/s13065-025-01545-8","DOIUrl":"10.1186/s13065-025-01545-8","url":null,"abstract":"<p><p>In response to the increasing demand for sustainable and high-throughput analytical approaches, this study presents the development and validation of five innovative univariate spectrophotometric methods for the simultaneous determination of amoxicillin trihydrate and diclofenac sodium in both synthetic mixtures and combined pharmaceutical dosage forms. The proposed methods, comprising first derivative, second derivative, ratio difference, ratio derivative, and ratio subtraction techniques, were designed to address the challenge of overlapping UV spectra, offering enhanced selectivity without the need for complex instrumentation or prior separation. Each method was meticulously optimized and validated in accordance with ICH Q2(R1) guidelines, demonstrating excellent linearity, accuracy, precision, and robustness. The analytical performance affirms their applicability for routine quality control of the studied drugs in a variety of formulations. Moreover, the environmental footprint of the methods was rigorously assessed using three complementary greenness evaluation tools: the GAPI, NEMI and Analytical eco scale, all of which confirmed the eco-friendly nature of the protocols. These results position the developed methods as a cost-effective, rapid, and green alternative for quality assurance in pharmaceutical laboratories, striking a valuable balance between analytical reliability and environmental responsibility.</p>","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"168"},"PeriodicalIF":4.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DNA as a polyionic ionophore for barium sensor. DNA作为多离子离子载体用于钡传感器。
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-19 DOI: 10.1186/s13065-025-01519-w
M M Zareh, A F El-Farargy, A Abd-ElSattar, Eman Rabie Abd-El-Rady, Badr Abd-El-Wahaab
{"title":"DNA as a polyionic ionophore for barium sensor.","authors":"M M Zareh, A F El-Farargy, A Abd-ElSattar, Eman Rabie Abd-El-Rady, Badr Abd-El-Wahaab","doi":"10.1186/s13065-025-01519-w","DOIUrl":"10.1186/s13065-025-01519-w","url":null,"abstract":"<p><p>The development of a highly selective and sensitive Ba<sup>2+</sup> sensor is crucial because of its industrial, environmental, and biological relevance. This study introduces a novel coated wire barium-selective electrode incorporating DNA as an ecofriendly natural ionophore in a plastic membrane, utilizing dioctyl phthalate as a plasticizer. The use of DNA as an ionophore provides enhanced selectivity and sensitivity, showcasing a slope of 33.15 mV/decade across a broad concentration range (1 × 10⁻<sup>5</sup> to 1 × 10⁻<sup>2</sup> M). The sensor exhibited a rapid response time of 9 s, a wide pH tolerance (2.6-6.9), and good selectivity for Ba<sup>2+</sup> over other cations. Characterization of the membrane using FT-IR, SEM, and EDX confirmed its structural and morphological features. Practical applicability was demonstrated by detecting Ba<sup>2+</sup> in spiked samples (milk, juice, tap water and urine) with recovery rates of 96.07-98.9%. This DNA-based approach offers a promising advancement in ion-selective electrode technology, with significant implications for real-world Ba<sup>2+</sup> detection.</p>","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"172"},"PeriodicalIF":4.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Watercress-derived glucosinolates as potential allosteric PTP1B inhibitors: a dual in silico and in vitro study on insulin signaling modulation. 豆瓣菜衍生的硫代葡萄糖苷作为潜在的变抗PTP1B抑制剂:胰岛素信号调节的双重体内和体外研究
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-19 DOI: 10.1186/s13065-025-01544-9
Noha A Ahmed, Ahmed A Allam, Hassan A Rudayni, Fahad M Alshabrmi, Faris F Aba Alkhayl, Doaa A Abdelrheem, Al Mokhtar Lamsabhi, Sarah I Othman, Emadeldin M Kamel
{"title":"Watercress-derived glucosinolates as potential allosteric PTP1B inhibitors: a dual in silico and in vitro study on insulin signaling modulation.","authors":"Noha A Ahmed, Ahmed A Allam, Hassan A Rudayni, Fahad M Alshabrmi, Faris F Aba Alkhayl, Doaa A Abdelrheem, Al Mokhtar Lamsabhi, Sarah I Othman, Emadeldin M Kamel","doi":"10.1186/s13065-025-01544-9","DOIUrl":"10.1186/s13065-025-01544-9","url":null,"abstract":"<p><p>This study investigates the inhibitory potential of four glucosinolates-glucoerucin, glucoiberin, gluconasturtiin, and glucotropaeolin-isolated from watercress (Nasturtium officinale) against Protein Tyrosine Phosphatase 1B (PTP1B), a key regulator of insulin signaling. Molecular docking, molecular dynamics (MD) simulations, and MM/PBSA free energy calculations identified glucoerucin (-17.18 ± 3.51 kcal/mol) and gluconasturtiin (-13.54 ± 1.79 kcal/mol) as the strongest binders, with stable interactions involving Phe280 and Phe196 through π-π stacking. Potential Energy Landscape (PEL) analysis further confirmed that these two compounds occupied the most stable low-energy conformational states, reinforcing their favorable binding to PTP1B. In vitro enzyme inhibition assays provided experimental validation that glucoerucin (IC₅₀ = 6.07 ± 0.69 µM) and gluconasturtiin (IC₅₀ = 7.65 ± 0.45 µM) demonstrated the strongest inhibitory effects, comparable to ursolic acid (IC₅₀ = 7.11 ± 0.95 µM). Enzyme kinetics revealed a non-competitive inhibition mechanism, with K<sub>i</sub> values of 6.29 µM and 7.02 µM, suggesting allosteric regulation. ADMET analysis indicated good solubility and metabolic stability but limited oral bioavailability due to low gastrointestinal (GI) absorption. These findings highlight glucoerucin and gluconasturtiin as promising natural PTP1B inhibitors, warranting further optimization for therapeutic applications in type 2 diabetes management.</p>","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"169"},"PeriodicalIF":4.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spectrofluorimetric determination of cyclic guanosine monophosphate in human nasal secretions: evaluating levels in healthy individuals and patients with olfactory dysfunction. 荧光光谱法测定人鼻分泌物中单磷酸环鸟苷:评估健康个体和嗅觉功能障碍患者的水平。
IF 4.3 2区 化学
BMC Chemistry Pub Date : 2025-06-19 DOI: 10.1186/s13065-025-01530-1
Mohamed H Abdelazim, Faisal Alsenani, Adnan Alharbi, Fahad H Baali, Abdulaziz H Baali, Maram H Abduljabbar, Reem M Alnemari, Majed A Algarni
{"title":"Spectrofluorimetric determination of cyclic guanosine monophosphate in human nasal secretions: evaluating levels in healthy individuals and patients with olfactory dysfunction.","authors":"Mohamed H Abdelazim, Faisal Alsenani, Adnan Alharbi, Fahad H Baali, Abdulaziz H Baali, Maram H Abduljabbar, Reem M Alnemari, Majed A Algarni","doi":"10.1186/s13065-025-01530-1","DOIUrl":"10.1186/s13065-025-01530-1","url":null,"abstract":"","PeriodicalId":496,"journal":{"name":"BMC Chemistry","volume":"19 1","pages":"171"},"PeriodicalIF":4.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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