Sao Paulo Medical Journal最新文献

{"title":"Correlation between depressive and anxious symptoms and white matter changes in relatives of people with epilepsy","authors":"Gabriel Ferri Baltazar, L. Ribeiro, M. Nogueira, Ricardo Brioschi, L. Silva, R. Joao, M. Alvim, F. Cendes, C. Yasuda","doi":"10.5327/1516-3180.616","DOIUrl":"https://doi.org/10.5327/1516-3180.616","url":null,"abstract":"Background: depression and anxiety are common symptoms observed in people with epilepsy and their relatives. Objective: Investigate associations between white matter (WM) changes and psychiatric symptoms in relatives of TLE patients. Methods: We analyzed brain MRI with DTI from 40 TLE relatives and applied the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). We extracted 6 WM tracts (fornix, cingulum, uncinate fasciculus (UF), inferior fronto-occipital fasciculus, corpus callosum, corticospinal tract) and analyzed fractional anisotropy (FA), medium diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD). We investigated correlations between scores and the DTI measures. Symptoms of depression were positive with BDI scores above 10, while symptoms of anxiety were positive with BAI scores above 11. Results: we observed a prevalence of 37.5% of depressive symptoms and 27.5% of anxious symptoms. BDI correlated with FA in the left cingulum (p=0.0003;r=-0.547); and with MD in the right cingulum (p=0.015;r=0.401) and right and left UF (p=0.023;r=0.374 and p=0.021;r=0.363). BDI correlated also with RD in the left and right cingulum (p=0.0003;r=0.583 and p=0.015;r=0.401). BAI correlated with fornix`s FA (p=0.026;r=- 0.352), and with MD in the left cingulum (p=0.01;r=0.415) and left UF (p=0.003;r=0.374) and with RD in the left cingulum (p=0.022;r=0.371) and left UF (p=0.01;r=0.440). Discussion: The regions correlated with psychiatric symptoms here overlap with those affected in patients with epilepsy, however, they differ from areas mainly affected in patients with isolated depression. We hypothesize a possible genetic substrate involved in comorbidity between epilepsy and depression, distinct from psychiatric disease in people without epilepsy.","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70976356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HANDS-ON: Training Simulation in Surgery.","authors":"Carlos Manuel de Almeida Brandão, Paulo Manuel Pêgo-Fernandes","doi":"10.1590/1516-3180.2022.1413230223","DOIUrl":"https://doi.org/10.1590/1516-3180.2022.1413230223","url":null,"abstract":"Methods of the teaching-learning binomial in surgery has undergone major transformations in the last decade, moving from purely informational content models of environments that stimulate theoretical “know-how” by incorporating skills and competencies. There has been a paradigm shift in the training of surgical residents from the traditional ‘‘apprenticeship’’ model to a hybrid one, involving simulation training. This shift has been in response to several current challenges in residency training, including time constraints, patient safety concerns, financial costs, and decreasing durations of training programs. 1 During the past several years, major shifts in surgical education have brought into question whether surgical residency programs could truly ensure competency and technical proficiency in these surgeons. 2 Simulation is an increasingly vital component of graduate medical education and becoming the standard of practice in many residency programs, particularly in surgical specialties, owing to the need for moving basic skill acquisition out of operating rooms into surgical skill laboratories. Deliberate practice is an educational technique that aims to improve performance through intense training and preparation. These steps include repetition, assessment, and feedback, which lead to performance improvement. 3","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9686281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in Managing a Medical School.","authors":"Paulo Manuel Pêgo-Fernandes, Eloisa Bonfá","doi":"10.1590/1516-3180.2022.141216122022","DOIUrl":"https://doi.org/10.1590/1516-3180.2022.141216122022","url":null,"abstract":"We recently had the honor and enormous challenge of taking over as co-directors of the School of Medicine of the University of São Paulo (FMUSP). FMUSP has been nationally and internationally recognized for its pioneering spirit and excellence, both in terms of teaching and research and university extension. It has been training professionals for 110 years in the fields of medicine, physiotherapy, speech therapy, and occupational therapy, and the most recent Medical Physics Program establishes a partnership between the School of Medicine and the Physics Institute of the University of São Paulo. Our numbers speak for themselves: we have approximately 1,400 undergraduate students; more than 1,000 employees, including 368 professors; 2,000 graduate students; and 1,600 residents. We publish more than 2,500 scientific articles annually. Our Clinical Hospital (CH) is the largest hospital in Latin America, a state institution linked to the Secretary of Health of the State of São Paulo for administrative coordination purposes and associated with FMUSP for teaching, research, health initiatives, and community services. The CH comprises eight institutes (Central Institute, Psychiatry Institute, Heart Institute, Radiology Institute, Cancer Institute, Institute for Children and Adolescents, Orthopedics and Traumatology Institute, and Physical Medicine and Rehabilitation Institute) and two auxiliary hospitals (Suzano Auxiliary Hospital and Cotoxó Hospital Complex). Annually, we provide more than one million outpatient appointments, 180,000 urgent and emergency care appointments, and approximately 50,000 surgeries. We are one of the largest medical-scientific research centers in Brazil, with 66 medical investigation laboratories, 230 research groups, and extensive intellectual output. Our faculty and healthcare professionals represent a huge competitive advantage for obtaining resources in the areas of clinical research, innovation, education, and assistance. Many of our professors are among the most influential researchers in the world, according to an assessment by the British consultancy Clarivate Analytics.1 In the search for community-based planning that reflects the best strategies to meet the institution’s needs and define its future directions, the FMUSP 2030 strategic plan was prepared in December 2021 to outline new goals, processes, and guidelines for the new cycle that has just begun. Several CH leaders and representatives from the Zerbini Foundation (ZF) and the School of Medicine Foundation (SMF) participated in it. Planning is integrated between the FMUSP and the CH, with a focus on care, technical, and administrative teaching processes, research and innovation actions, and human resources. The actions are developed according to strategic axes, which deal with current themes of high social relevance, such as Excellence in Teaching, Culture, and Extension; Excellence in Care; Integration; Humanization-Participatory Management; Internationalizatio","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9517600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1590/1516-3180.2022.0281.R1.300820221erratum","DOIUrl":"https://doi.org/10.1590/1516-3180.2022.0281.R1.300820221erratum","url":null,"abstract":"<p><p>[This corrects the article doi: 10.1590/1516-3180.2022.0281.R1.30082022].</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9158050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of methimazole before the administration of radioactive iodine in the management of Graves' disease: a systematic review and meta-analysis.","authors":"Ikeoluwapo Kendra Bolakale-Rufai, Imodoye Abioro, Samuel Osobuchi Ngene, Yohannes Woldeamanuel","doi":"10.1590/1516-3180.2022.0225.R1.19102022","DOIUrl":"10.1590/1516-3180.2022.0225.R1.19102022","url":null,"abstract":"<p><strong>Background: </strong>The efficacy of anti-thyroid drugs in conjunction with radioactive iodine therapy in the management of Graves' disease is still controversial.</p><p><strong>Objective: </strong>To compare the efficacy of pretreatment with methimazole before the administration of radioactive iodine for the treatment of Graves' disease.</p><p><strong>Design and setting: </strong>A systematic review and meta-analysis was conducted at a teaching/tertiary hospital in Ibadan, Nigeria.</p><p><strong>Methods: </strong>A systematic search of the PubMed, Embase, Cochrane Library, and Web of Science databases was performed from inception to December, 2021.</p><p><strong>Results: </strong>Five studies with 297 participants were included. There was no difference in the risk of persistent hyperthyroidism when radioactive iodine was used in conjunction with methimazole compared with when radioactive iodine was used alone (relative risk: 1.02, 95% confidence interval, CI: 0.62-1.66; P = 0.95, I2 = 0%). Subgroup analysis based on the duration between discontinuation of methimazole and the administration of radioactive iodine showed a lower risk of persistent hyperthyroidism when methimazole was discontinued within 7 days before radioactive iodine use, although this did not reach statistical significance (risk ratio: 0.85, CI: 0.28-2.58).</p><p><strong>Conclusions: </strong>The use of methimazole before radioactive iodine administration was not associated with an increased risk of persistent hyperthyroidism. Concerns about medication toxicity and adverse effects should be considered when clinicians make decisions on combination therapies for the treatment of Graves' disease.</p><p><strong>Prospero registration: </strong>CRD42020150013, https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=150013.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9619458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally invasive interventions for biopsy of malignancy-suspected pulmonary nodules: a systematic review and meta-analysis.","authors":"André Miotto,&nbsp;João Aléssio Juliano Perfeito,&nbsp;Rafael Leite Pacheco,&nbsp;Carolina de Oliveira Cruz Latorraca,&nbsp;Rachel Riera","doi":"10.1590/1516-3180.2022.0543.R1.01022023","DOIUrl":"https://doi.org/10.1590/1516-3180.2022.0543.R1.01022023","url":null,"abstract":"<p><strong>Background: </strong>Imaging tests are important for diagnosis during the management of pulmonary nodules; however, biopsy is required to confirm the malignancy.</p><p><strong>Objectives: </strong>To compare the effects of different techniques used for the biopsy of a pulmonary nodule.</p><p><strong>Design and setting: </strong>Systematic review and meta-analysis were conducted using Cochrane methodology in São Paulo, São Paulo, Brazil.</p><p><strong>Methods: </strong>We conducted a systematic review of randomized controlled trials (RCTs) on minimally invasive techniques, including tomography-guided percutaneous biopsy (PERCUT), transbronchial biopsies with fluoroscopy (FLUOR), endobronchial ultrasound (EBUSR), and electromagnetic navigation (NAVIG). The primary outcomes were diagnostic yield, major adverse events, and need for another approach.</p><p><strong>Results: </strong>Seven RCTs were included (913 participants; 39.2% female, mean age: 59.28 years). Little to no increase was observed in PERCUT over FLUOR (P = 0.84), PERCUT over EBUSR (P = 0.32), and EBUSR over NAVIG (P = 0.17), whereas a slight increase was observed in NAVIG over FLUOR (P = 0.17); however, the evidence was uncertain. EBUSR may increase the diagnostic yield over FLUOR (P = 0.34). PERCUT showed little to no increase in all bronchoscopic techniques, with uncertain evidence (P = 0.02).</p><p><strong>Conclusion: </strong>No biopsy method is definitively superior to others. The preferred approach must consider availability, accessibility, and cost, as safety and diagnostic yield do not differ. Further RCTs planned, conducted, and reported with methodological rigor and transparency are needed, and additional studies should assess cost and the correlation between nodule size and location, as well as their association with biopsy results.</p><p><strong>Systematic review registration: </strong>PROSPERO database, CRD42018092367 -https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=92367.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9425740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presenteeism and noise perception at work: a cross-sectional study using association analysis.","authors":"Renata da Silva Cardoso Rocha Tavares,&nbsp;Luiz Felipe Silva,&nbsp;Jorge Muniz Júnior","doi":"10.1590/1516-3180.2021.0792.R2.07042022","DOIUrl":"https://doi.org/10.1590/1516-3180.2021.0792.R2.07042022","url":null,"abstract":"<p><strong>Background: </strong>Presenteeism refers to the presence of a worker at work with reduced performance due to illness, and it is a common public health problem. Exposure to noise during production processes brings risk to workers' health.</p><p><strong>Objective: </strong>To analyze the health profile of workers in the automotive industry and identify the association between noise perception and presenteeism among workers in the Brazilian automotive industry.</p><p><strong>Design and setting: </strong>This was a cross-sectional study utilizing a case study design analyzing the automotive industry in the interior of São Paulo state, Brazil.</p><p><strong>Methods: </strong>This study included 306 workers using the Presenteeism Work Limitations Questionnaire protocol. Multiple logistic regression was used for data analysis.</p><p><strong>Results: </strong>Male workers with reports of headache, tension, and limited well-being at work, having perceived that noise exposure interferes with productivity, showed a positive association with the occurrence of presenteeism. Physical demand had the highest score in terms of interfering with the presenteeism index.</p><p><strong>Conclusion: </strong>Workers' perceptions of noise were associated with presenteeism.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10478119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive mechanical ventilation assistance in amyotrophic lateral sclerosis: a systematic review.","authors":"Carolina da Cunha-Correia,&nbsp;Mylana Dandara Pereira Gama,&nbsp;Pedro Nogueira Fontana,&nbsp;Francisca Goreth Malheiro Moraes Fantini,&nbsp;Gilmar Fernandes Prado,&nbsp;Mário Emílio Teixeira Dourado Júnior,&nbsp;Paulo Adriano Schwingel","doi":"10.1590/1516-3180.2022.0470.R1.100423","DOIUrl":"https://doi.org/10.1590/1516-3180.2022.0470.R1.100423","url":null,"abstract":"<p><strong>Background: </strong>Respiratory failure is the most common cause of death in patients with amyotrophic lateral sclerosis (ALS), and morbidity is related to poor quality of life (QOL). Non-invasive ventilation (NIV) may be associated with prolonged survival and QOL in patients with ALS.</p><p><strong>Objectives: </strong>To assess whether NIV is effective and safe for patients with ALS in terms of survival and QOL, alerting the health system.</p><p><strong>Design and setting: </strong>Systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting standards using population, intervention, comparison, and outcome strategies.</p><p><strong>Methods: </strong>The Cochrane Library, CENTRAL, MEDLINE, LILACS, EMBASE, and CRD databases were searched based on the eligibility criteria for all types of studies on NIV use in patients with ALS published up to January 2022. Data were extracted from the included studies, and the findings were presented using a narrative synthesis.</p><p><strong>Results: </strong>Of the 120 papers identified, only 14 were related to systematic reviews. After thorough reading, only one meta-analysis was considered eligible. In the second stage, 248 studies were included; however, only one systematic review was included. The results demonstrated that NIV provided relief from the symptoms of chronic hypoventilation, increased survival, and improved QOL compared to standard care. These results varied according to clinical phenotype.</p><p><strong>Conclusions: </strong>NIV in patients with ALS improves the outcome and can delay the indication for tracheostomy, reducing expenditure on hospitalization and occupancy of intensive care unit beds.</p><p><strong>Systematic review registration: </strong>PROSPERO database: CRD42021279910 - https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=279910.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9834062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Brazilian Portuguese version of the Pregnancy Mobility Index: Cross-cultural adaptation and psychometric evaluation - a validation study.","authors":"Maria Izabel Feltrin,&nbsp;Rubneide Barreto Silva Gallo,&nbsp;Elisa Gabardo Lima,&nbsp;Nayara Helena Gomes Bertoncini,&nbsp;Jordana Barbosa da Silva,&nbsp;Natália Boneti Moreira,&nbsp;Raciele Ivandra Guarda Korelo","doi":"10.1590/1516-3180.2022.0279.R1.19122022","DOIUrl":"https://doi.org/10.1590/1516-3180.2022.0279.R1.19122022","url":null,"abstract":"<p><strong>Background: </strong>The Pregnancy Mobility Index (PMI) was developed to assess mobility in pregnant women in the Netherlands. At present, no similar questionnaire is available in Brazil.</p><p><strong>Objective: </strong>The present study aimed to translate, cross-culturally adapt, and evaluate the psychometric properties of a Brazilian PMI.</p><p><strong>Design and setting: </strong>The present study was a validation study conducted at the Universidade Federal do Paraná and a public maternity ward in Curitiba, Brazil.</p><p><strong>Methods: </strong>Text translation and cross-cultural adaptation followed international guidelines. Construct validity, internal consistency, and inter- and intra-rater reliability tests included 97 women. The Pelvic Girdle Questionnaire, Multidimensional Pain Evaluation Scale, Schober's test, and lumbar spine range of motion assessment were administered on the first day. Intra-rater reliability (n = 19) was measured after 15 days. Exploratory factor analysis was performed, and the correlation matrix was analyzed using Pearson's coefficient.</p><p><strong>Results: </strong>Pregnant women (88%) understood the cultural adaptation process. The internal consistency was high (Cronbach's alpha > 0.90), construct validity was moderate, with significant correlation between lumbar spine range of motion (r = 0.283-0.369) and Schober's test (r = -0.314), and high correlation between the Multidimensional Pain Evaluation Scale (r = -0.650 and -0.499) and Pelvic Girdle Questionnaire (r = -0.737). Intra- and inter-rater reliabilities were excellent (intraclass correlation coefficient = 0.932 and 0.990, respectively).</p><p><strong>Conclusion: </strong>The Brazilian version of the PMI was successfully translated with excellent reliability and moderate-to-high construct validity. It is an important tool for assessing mobility in pregnant women.</p><p><strong>Clinical trial: </strong>RBR-789tps (Validation study), https://ensaiosclinicos.gov.br/rg/RBR-789tps.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9845000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Which anthropometric equation to predict body fat percentage is more strongly associated with maximum oxygen uptake in adolescents? A cross-sectional study.","authors":"Eliane Cristina de Andrade Gonçalves,&nbsp;Nelson Nardo Júnior,&nbsp;Michele Caroline de Souza Ribas,&nbsp;Diego Augusto Santos Silva","doi":"10.1590/1516-3180.2022.0437.R1.07022023","DOIUrl":"https://doi.org/10.1590/1516-3180.2022.0437.R1.07022023","url":null,"abstract":"<p><strong>Background: </strong>Identifying the relationship between maximum consumption of oxygen and body fat percentage is important due to increased cardiovascular risk factors.</p><p><strong>Objective: </strong>This study aimed to verify the association between body fat percentage determined by three predictive equations using anthropometric measures (Lohman, Boileau, and Slaughter) and maximum oxygen uptake (VO2max). We also aimed to estimate the capacity of these equations for explaining VO2max variations in adolescents according to sex.</p><p><strong>Design and setting: </strong>This was a cross-sectional study conducted in high schools in São José, Southern Brazil.</p><p><strong>Methods: </strong>This study included 879 adolescents (14-19 years) from Southern Brazil. Aerobic fitness was assessed using the modified Canadian Aerobic Fitness Test. The independent variable was body fat percentage predicted by the Lohman, Boileau, and Slaughter equations. Analyses adjusted for sociodemographic variables, physical activity level, and sexual maturation were performed with P value < 0.05.</p><p><strong>Results: </strong>All anthropometric prediction equations used to estimate body fat percentage explained VO2max variations in adolescents. In male adolescents, both regression models based on the Boileau et al.12 and Lohman10 equations revealed higher explanatory power for VO2max (20%) compared with that based on the Slaughter et al.13 equation (19%). In female adolescents, the model based on the anthropometric equation of Slaughter et al.13 showed the greatest explanatory power for VO2max (18%).</p><p><strong>Conclusion: </strong>The inverse relationship between VO2max and body fat intensifies the need for effective intervention programs that prioritize maintenance of appropriate body fat and aerobic fitness levels because inadequate levels of both factors result in negative health consequences.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9980760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}