Aysu Yıldız Karaahmet, Gülümser Dolgun, Metehan Özen
{"title":"益生菌对肠绞痛婴儿胃肠道症状、人体测量和母乳喂养时间的影响：随机对照试验。","authors":"Aysu Yıldız Karaahmet, Gülümser Dolgun, Metehan Özen","doi":"10.1590/1516-3180.2023.0069.R1.31052023","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Infantile colic has a multifactorial etiology. Recent studies have suggested that probiotics may be effective in its management.</p><p><strong>Objective: </strong>This study was carried out to evaluate the effect of the Actiregularis strain (5×106 cfu\\ml) included in maternal nutrition on gastrointestinal problems, growth development, and breastfeeding outcomes in infantile colic.</p><p><strong>Design and setting: </strong>The study was a randomized controlled trial conducted in the neonatal outpatient clinic of a training and research hospital in Turkey.</p><p><strong>Methods: </strong>A probiotic drink containing the Actiregularis (5×106 cfu\\ml) strain was added to the diet of mothers in the probiotics group once daily for 15 consecutive days. Data were collected for each infant's 0th (birth), 1st, 4th, and 6th months.</p><p><strong>Results: </strong>Infants whose mothers were administered Actiregularis for 15 days had decreased crying intensity (P = 0.000). When the difference in breastfeeding rates between the groups was significant at the 4th and 6th months (P = 0.044; P = 0.035). There was no difference in anthropometric values except the babies' weights at the 6th month. (P < 0.001).</p><p><strong>Conclusion: </strong>Infants treated with Actiregularis, which was added to their mothers' diet for 15 days, showed a decrease in the frequency of crying, and the difference in breastfeeding rates between the groups was significant at the 4th and 6th months. There was no difference in anthropometric values except the babies' weights at the 6th month.</p><p><strong>Clinical trials registration: </strong>NCT04374955 (https://clinicaltrials.gov/ct2/show/).</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"142 4","pages":"e2023069"},"PeriodicalIF":1.3000,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034883/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effects of probiotics on gastrointestinal symptoms, anthropometric measurements, and breastfeeding duration in infants with colic: a randomized control trial.\",\"authors\":\"Aysu Yıldız Karaahmet, Gülümser Dolgun, Metehan Özen\",\"doi\":\"10.1590/1516-3180.2023.0069.R1.31052023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Infantile colic has a multifactorial etiology. Recent studies have suggested that probiotics may be effective in its management.</p><p><strong>Objective: </strong>This study was carried out to evaluate the effect of the Actiregularis strain (5×106 cfu\\\\ml) included in maternal nutrition on gastrointestinal problems, growth development, and breastfeeding outcomes in infantile colic.</p><p><strong>Design and setting: </strong>The study was a randomized controlled trial conducted in the neonatal outpatient clinic of a training and research hospital in Turkey.</p><p><strong>Methods: </strong>A probiotic drink containing the Actiregularis (5×106 cfu\\\\ml) strain was added to the diet of mothers in the probiotics group once daily for 15 consecutive days. Data were collected for each infant's 0th (birth), 1st, 4th, and 6th months.</p><p><strong>Results: </strong>Infants whose mothers were administered Actiregularis for 15 days had decreased crying intensity (P = 0.000). When the difference in breastfeeding rates between the groups was significant at the 4th and 6th months (P = 0.044; P = 0.035). There was no difference in anthropometric values except the babies' weights at the 6th month. (P < 0.001).</p><p><strong>Conclusion: </strong>Infants treated with Actiregularis, which was added to their mothers' diet for 15 days, showed a decrease in the frequency of crying, and the difference in breastfeeding rates between the groups was significant at the 4th and 6th months. There was no difference in anthropometric values except the babies' weights at the 6th month.</p><p><strong>Clinical trials registration: </strong>NCT04374955 (https://clinicaltrials.gov/ct2/show/).</p>\",\"PeriodicalId\":49574,\"journal\":{\"name\":\"Sao Paulo Medical Journal\",\"volume\":\"142 4\",\"pages\":\"e2023069\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-04-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034883/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sao Paulo Medical Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1590/1516-3180.2023.0069.R1.31052023\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sao Paulo Medical Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1590/1516-3180.2023.0069.R1.31052023","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Effects of probiotics on gastrointestinal symptoms, anthropometric measurements, and breastfeeding duration in infants with colic: a randomized control trial.
Background: Infantile colic has a multifactorial etiology. Recent studies have suggested that probiotics may be effective in its management.
Objective: This study was carried out to evaluate the effect of the Actiregularis strain (5×106 cfu\ml) included in maternal nutrition on gastrointestinal problems, growth development, and breastfeeding outcomes in infantile colic.
Design and setting: The study was a randomized controlled trial conducted in the neonatal outpatient clinic of a training and research hospital in Turkey.
Methods: A probiotic drink containing the Actiregularis (5×106 cfu\ml) strain was added to the diet of mothers in the probiotics group once daily for 15 consecutive days. Data were collected for each infant's 0th (birth), 1st, 4th, and 6th months.
Results: Infants whose mothers were administered Actiregularis for 15 days had decreased crying intensity (P = 0.000). When the difference in breastfeeding rates between the groups was significant at the 4th and 6th months (P = 0.044; P = 0.035). There was no difference in anthropometric values except the babies' weights at the 6th month. (P < 0.001).
Conclusion: Infants treated with Actiregularis, which was added to their mothers' diet for 15 days, showed a decrease in the frequency of crying, and the difference in breastfeeding rates between the groups was significant at the 4th and 6th months. There was no difference in anthropometric values except the babies' weights at the 6th month.
期刊介绍：
Published bimonthly by the Associação Paulista de Medicina, the journal accepts articles in the fields of clinical health science (internal medicine, gynecology and obstetrics, mental health, surgery, pediatrics and public health). Articles will be accepted in the form of original articles (clinical trials, cohort, case-control, prevalence, incidence, accuracy and cost-effectiveness studies and systematic reviews with or without meta-analysis), narrative reviews of the literature, case reports, short communications and letters to the editor. Papers with a commercial objective will not be accepted.
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