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Seminars in Musculoskeletal Radiology最新文献

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Biomarkers in Musculoskeletal Imaging. 肌肉骨骼成像中的生物标记物。
IF 1.4 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2024-02-01 Epub Date: 2024-02-08 DOI: 10.1055/s-0043-1778018
Richard Kijowski
{"title":"Biomarkers in Musculoskeletal Imaging.","authors":"Richard Kijowski","doi":"10.1055/s-0043-1778018","DOIUrl":"10.1055/s-0043-1778018","url":null,"abstract":"","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"28 1","pages":"1-2"},"PeriodicalIF":1.4,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gustav Peter Bucky: An Engineer in the Service of Health. 古斯塔夫-彼得-巴奇：为健康服务的工程师。
IF 1.4 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2024-02-01 Epub Date: 2024-02-08 DOI: 10.1055/s-0043-1776053
Iwona Sudoł-Szopińska, Marta Panas-Goworska, Christian Glaser
{"title":"Gustav Peter Bucky: An Engineer in the Service of Health.","authors":"Iwona Sudoł-Szopińska, Marta Panas-Goworska, Christian Glaser","doi":"10.1055/s-0043-1776053","DOIUrl":"10.1055/s-0043-1776053","url":null,"abstract":"<p><p>This history page in the series \"Leaders in MSK radiology\" is dedicated to the memory and achievements of the German radiologist Gustav Peter Bucky who invented the Bucky diaphragm grids. He wanted to become an engineer but bowed to his parents' wishes and went to medical school. By using his technical skills, he made revolutionary contributions to the early X-ray technique.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"28 1","pages":"103-104"},"PeriodicalIF":1.4,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing Diagnostics and Patient Care: The Role of Biomarkers in Radiology. 推进诊断和患者护理：生物标志物在放射学中的作用。
IF 1.4 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2024-02-01 Epub Date: 2024-02-08 DOI: 10.1055/s-0043-1776426
Ronnie Sebro
{"title":"Advancing Diagnostics and Patient Care: The Role of Biomarkers in Radiology.","authors":"Ronnie Sebro","doi":"10.1055/s-0043-1776426","DOIUrl":"10.1055/s-0043-1776426","url":null,"abstract":"<p><p>The integration of biomarkers into medical practice has revolutionized the field of radiology, allowing for enhanced diagnostic accuracy, personalized treatment strategies, and improved patient care outcomes. This review offers radiologists a comprehensive understanding of the diverse applications of biomarkers in medicine. By elucidating the fundamental concepts, challenges, and recent advancements in biomarker utilization, it will serve as a bridge between the disciplines of radiology and epidemiology. Through an exploration of various biomarker types, such as imaging biomarkers, molecular biomarkers, and genetic markers, I outline their roles in disease detection, prognosis prediction, and therapeutic monitoring. I also discuss the significance of robust study designs, blinding, power and sample size calculations, performance metrics, and statistical methodologies in biomarker research. By fostering collaboration between radiologists, statisticians, and epidemiologists, I hope to accelerate the translation of biomarker discoveries into clinical practice, ultimately leading to improved patient care.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"28 1","pages":"3-13"},"PeriodicalIF":1.4,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Up-and-coming Radiotracers for Imaging Pain Generators. 即将推出的用于疼痛发生器成像的放射性示踪剂。
IF 1.4 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI: 10.1055/s-0043-1775745
Rianne A van der Heijden, Sandip Biswal
{"title":"Up-and-coming Radiotracers for Imaging Pain Generators.","authors":"Rianne A van der Heijden, Sandip Biswal","doi":"10.1055/s-0043-1775745","DOIUrl":"10.1055/s-0043-1775745","url":null,"abstract":"<p><p>Chronic musculoskeletal pain is among the most highly prevalent diseases worldwide. Managing patients with chronic pain remains very challenging because current imaging techniques focus on morphological causes of pain that can be inaccurate and misleading. Moving away from anatomical constructs of disease, molecular imaging has emerged as a method to identify diseases according to their molecular, physiologic, or cellular signatures that can be applied to the variety of biomolecular changes that occur in nociception and pain processing and therefore have tremendous potential for precisely pinpointing the source of a patient's pain. Several molecular imaging approaches to image the painful process are now available, including imaging of voltage-gated sodium channels, calcium channels, hypermetabolic processes, the substance P receptor, the sigma-1 receptor, and imaging of macrophage trafficking. This article provides an overview of promising molecular imaging approaches for the imaging of musculoskeletal pain with a focus on preclinical methods.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"27 6","pages":"661-675"},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diffusion Tensor Imaging of Peripheral Nerves: Current Status and New Developments. 周围神经的扩散张量成像：现状和新进展。
IF 1.4 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI: 10.1055/s-0043-1775742
Daehyun Yoon, Amelie M Lutz
{"title":"Diffusion Tensor Imaging of Peripheral Nerves: Current Status and New Developments.","authors":"Daehyun Yoon, Amelie M Lutz","doi":"10.1055/s-0043-1775742","DOIUrl":"10.1055/s-0043-1775742","url":null,"abstract":"<p><p>Diffusion tensor imaging (DTI) is an emerging technique for peripheral nerve imaging that can provide information about the microstructural organization and connectivity of these nerves and complement the information gained from anatomical magnetic resonance imaging (MRI) sequences. With DTI it is possible to reconstruct nerve pathways and visualize the three-dimensional trajectory of nerve fibers, as in nerve tractography. More importantly, DTI allows for quantitative evaluation of peripheral nerves by the calculation of several important parameters that offer insight into the functional status of a nerve. Thus DTI has a high potential to add value to the work-up of peripheral nerve pathologies, although it is more technically demanding. Peripheral nerves pose specific challenges to DTI due to their small diameter and DTI's spatial resolution, contrast, location, and inherent field inhomogeneities when imaging certain anatomical locations. Numerous efforts are underway to resolve these technical challenges and thus enable wider acceptance of DTI in peripheral nerve MRI.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"27 6","pages":"641-648"},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advanced Magnetic Resonance Imaging and Molecular Imaging of the Painful Knee. 膝关节疼痛的高级磁共振成像和分子成像。
IF 1.4 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI: 10.1055/s-0043-1775741
Jacob M Mostert, Niels B J Dur, Xiufeng Li, Jutta M Ellermann, Robert Hemke, Laurel Hales, Valentina Mazzoli, Feliks Kogan, James F Griffith, Edwin H G Oei, Rianne A van der Heijden
{"title":"Advanced Magnetic Resonance Imaging and Molecular Imaging of the Painful Knee.","authors":"Jacob M Mostert, Niels B J Dur, Xiufeng Li, Jutta M Ellermann, Robert Hemke, Laurel Hales, Valentina Mazzoli, Feliks Kogan, James F Griffith, Edwin H G Oei, Rianne A van der Heijden","doi":"10.1055/s-0043-1775741","DOIUrl":"10.1055/s-0043-1775741","url":null,"abstract":"<p><p>Chronic knee pain is a common condition. Causes of knee pain include trauma, inflammation, and degeneration, but in many patients the pathophysiology remains unknown. Recent developments in advanced magnetic resonance imaging (MRI) techniques and molecular imaging facilitate more in-depth research focused on the pathophysiology of chronic musculoskeletal pain and more specifically inflammation. The forthcoming new insights can help develop better targeted treatment, and some imaging techniques may even serve as imaging biomarkers for predicting and assessing treatment response in the future. This review highlights the latest developments in perfusion MRI, diffusion MRI, and molecular imaging with positron emission tomography/MRI and their application in the painful knee. The primary focus is synovial inflammation, also known as synovitis. Bone perfusion and bone metabolism are also addressed.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"27 6","pages":"618-631"},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular and Functional Imaging of Musculoskeletal Pain, Inflammation, and Arthritis. 肌肉骨骼疼痛、炎症和关节炎的分子和功能成像。
IF 1.4 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI: 10.1055/s-0043-1776052
Sandip Biswal
{"title":"Molecular and Functional Imaging of Musculoskeletal Pain, Inflammation, and Arthritis.","authors":"Sandip Biswal","doi":"10.1055/s-0043-1776052","DOIUrl":"10.1055/s-0043-1776052","url":null,"abstract":"","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"27 6","pages":"599-600"},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EXPLORing Arthritis with Total-body Positron Emission Tomography. 用全身正电子发射断层扫描技术探索关节炎。
IF 0.9 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI: 10.1055/s-0043-1775746
Abhijit J Chaudhari, Yasser G Abdelhafez, Lorenzo Nardo, Siba P Raychaudhuri
{"title":"EXPLORing Arthritis with Total-body Positron Emission Tomography.","authors":"Abhijit J Chaudhari, Yasser G Abdelhafez, Lorenzo Nardo, Siba P Raychaudhuri","doi":"10.1055/s-0043-1775746","DOIUrl":"10.1055/s-0043-1775746","url":null,"abstract":"<p><p>Arthritis has significant adverse consequences on musculoskeletal tissues and often other organs of the body. Current methods for clinical evaluation of arthritis are suboptimal, and biomarkers that are objective and measurable indicators for monitoring of arthritis disease activity are in critical demand. Recently, total-body positron emission tomography (PET) has been developed that can collect imaging signals synchronously from the entire body at ultra-low doses and reduced scan times. These scanners have increased signal collection efficiency that overcomes several limitations of standard PET scanners in the evaluation of arthritis, and they may potentially provide biomarkers to assess local and systemic impact of the arthritis disease process. This article reviews current results from using total-body PET in the assessment of common arthritic conditions, and it outlines future opportunities and challenges.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"27 6","pages":"632-640"},"PeriodicalIF":0.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Practical Guide to Sigma-1 Receptor Positron Emission Tomography/Magnetic Resonance Imaging: A New Clinical Molecular Imaging Method to Identify Peripheral Pain Generators in Patients with Chronic Pain. Sigma-1受体正电子发射断层扫描/磁共振成像实用指南：一种新的临床分子成像方法，用于识别慢性疼痛患者的外周疼痛发生器。
IF 1.4 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI: 10.1055/s-0043-1775744
Bin Shen, Daehyun Yoon, Jessa Castillo, Sandip Biswal
{"title":"A Practical Guide to Sigma-1 Receptor Positron Emission Tomography/Magnetic Resonance Imaging: A New Clinical Molecular Imaging Method to Identify Peripheral Pain Generators in Patients with Chronic Pain.","authors":"Bin Shen, Daehyun Yoon, Jessa Castillo, Sandip Biswal","doi":"10.1055/s-0043-1775744","DOIUrl":"10.1055/s-0043-1775744","url":null,"abstract":"<p><p>Accurately identifying the peripheral pain generator in patients with chronic pain remains a major challenge for modern medicine. Millions of patients around the world suffer endlessly from difficult-to-manage debilitating pain because of very limited diagnostic tests and a paucity of pain therapies. To help these patients, we have developed a novel clinical molecular imaging approach, and, in its early stages, it has been shown to accurately identify the exact site of pain generation using an imaging biomarker for the sigma-1 receptor and positron emission tomography/magnetic resonance imaging. We hope the description of the work in this article can help others begin their own pain imaging programs at their respective institutions.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"27 6","pages":"601-617"},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiotracers in the Diagnosis of Pain: A Mini Review. 放射示踪剂在疼痛诊断中的应用：一篇小综述。
IF 1.4 4区 医学
Seminars in Musculoskeletal Radiology Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI: 10.1055/s-0043-1775743
Jacob Hascalovici, Anthony Babb, Braxton A Norwood
{"title":"Radiotracers in the Diagnosis of Pain: A Mini Review.","authors":"Jacob Hascalovici, Anthony Babb, Braxton A Norwood","doi":"10.1055/s-0043-1775743","DOIUrl":"10.1055/s-0043-1775743","url":null,"abstract":"<p><p>The diagnosis and understanding of pain is challenging in clinical practice. Assessing pain relies heavily on self-reporting by patients, rendering it inherently subjective. Traditional clinical imaging methods such as computed tomography and magnetic resonance imaging can only detect anatomical abnormalities, offering limited sensitivity and specificity in identifying pain-causing conditions. Radiotracers play a vital role in molecular imaging that aims to identify abnormal biological processes at the cellular level, even in apparently normal anatomical structures. Therefore, molecular imaging is an important area of research as a prospective diagnostic modality for pain-causing pathophysiology. We present a mini review of the current knowledge base regarding radiotracers for identification of pain in vivo. We also describe radiocaine, a novel positron emission tomography imaging agent for sodium channels that has shown great potential for identifying/labeling pain-producing nerves and producing an objectively measurable pain intensity signal.</p>","PeriodicalId":49545,"journal":{"name":"Seminars in Musculoskeletal Radiology","volume":"27 6","pages":"655-660"},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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