Suryansh Bajaj MD , Frank Chen MD , Jordan LeGout MD , Joseph Cernigliaro MD , Gitanjali Bajaj MD (Associate Professor) , Shweta Bhatt MBBS, MD
{"title":"Classic Imaging Signs in Hepatobiliary Radiology: A Multimodality Review","authors":"Suryansh Bajaj MD , Frank Chen MD , Jordan LeGout MD , Joseph Cernigliaro MD , Gitanjali Bajaj MD (Associate Professor) , Shweta Bhatt MBBS, MD","doi":"10.1053/j.sult.2025.09.002","DOIUrl":"10.1053/j.sult.2025.09.002","url":null,"abstract":"<div><div>Classic radiological signs in imaging serve as visual clues that aid in narrowing the differential diagnosis and enhancing diagnostic confidence. This review article highlights key imaging signs encountered in hepatic pathology across multiple modalities including ultrasound, CT, and MRI. We explore some of the characteristic signs associated with hepatic neoplastic, infectious, vascular lesions, anatomicvariations and miscellaneous conditions, discussing their pathophysiology, diagnosticutility and clinical relevance. By revisiting these classic signs, radiologists can reinforce pattern recognition skills essential for accurate interpretation. This article aims to serve as a practicalreference and educational resource for radiologists, trainees and clinicians involved in hepatic imaging.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 428-439"},"PeriodicalIF":1.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intraductal Papillary Neoplasm of the Bile Duct: Simplifying Findings","authors":"Nathália Gonçalves Dias MD , Julia de Toledo Mendes MD , Bruna Andreucci Kozlowski MD , Daniella Braz Parente MD, PhD , Daniel Lahan Martins MD, PhD , Thiago Franchi Nunes MD, PhD , Matheus Menezes Gomes MD , Aley Talans MD , Eduardo Oliveira Pacheco MD , Ulysses S. Torres MD, PhD , Guiseppe D'ippolito MD, PhD","doi":"10.1053/j.sult.2025.09.005","DOIUrl":"10.1053/j.sult.2025.09.005","url":null,"abstract":"<div><div>Intraductal papillary neoplasm of the bile duct (IPNB) is a rare tumor, considered a pre-invasive lesion derived from the biliary epithelium. Although it shares similarities with intraductal papillary mucinous neoplasm (IPMN) of the pancreas, only one-third of patients present with mucin hypersecretion. The World Health Organization (WHO) formalized the description of IPNB in 2010 as a \"non-invasive biliary papillary or villous neoplasm covering delicate fibrovascular stalks in dilated bile ducts.\" Despite advancements, literature still lacks multicenter studies on its progression and prognosis. This article reviews the clinical, epidemiological, and radiological features of IPNB, highlighting its recent classifications and key findings, contributing to appropriate management based on a literature review and case examples.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 415-427"},"PeriodicalIF":1.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matheus M. Gomes MD , Gabriel T. Lingiardi MD , Cynthia L.P. Borborema MD , Eduardo O. Pacheco MD , Daniella B. Parente MD, PhD , Ulysses S. Torres MD, PhD , Giuseppe D’Ippolito MD, PhD
{"title":"Periportal Space Lesions: Imaging Spectrum and Differential Diagnosis","authors":"Matheus M. Gomes MD , Gabriel T. Lingiardi MD , Cynthia L.P. Borborema MD , Eduardo O. Pacheco MD , Daniella B. Parente MD, PhD , Ulysses S. Torres MD, PhD , Giuseppe D’Ippolito MD, PhD","doi":"10.1053/j.sult.2025.09.003","DOIUrl":"10.1053/j.sult.2025.09.003","url":null,"abstract":"<div><div>The periportal region is a complex anatomical area that includes important structures such as the hepatic artery, bile ducts, lymphatics, and nerves. Due to its rich architecture, diagnosing lesions in this space presents a significant challenge for radiologists. Various pathological conditions can affect this region, ranging from vascular and lymphatic diseases to infectious and malignant lesions. This article explores the main periportal conditions through various imaging methods, including ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and magnetic resonance cholangiopancreatography (MRCP). Therefore, understanding specific radiological manifestations is essential for differentiating clinical conditions and guiding appropriate treatment.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 399-414"},"PeriodicalIF":1.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Paula Bavaresco MD , Ulysses S. Torres MD, PhD , Mayara S. Cruz MD , Vitor V.C. Machado MD , Cynthia L.P. Borborema MD , Giovanna S. Torre MD , Jhonata Soares Da Silva MD , Tulio A. Kawai MD , Gustavo R.A. Focchi MD , Eduardo O. Pacheco MD , Aley Talans MD , Daniel Bekhor MD , Ana Paula C. Moura MD , Lucas R. Torres MD , Giuseppe D'Ippolito MD, PhD
{"title":"Imaging of Gynecologic Neuroendocrine Tumors: A Case-Based Pictorial Essay","authors":"Ana Paula Bavaresco MD , Ulysses S. Torres MD, PhD , Mayara S. Cruz MD , Vitor V.C. Machado MD , Cynthia L.P. Borborema MD , Giovanna S. Torre MD , Jhonata Soares Da Silva MD , Tulio A. Kawai MD , Gustavo R.A. Focchi MD , Eduardo O. Pacheco MD , Aley Talans MD , Daniel Bekhor MD , Ana Paula C. Moura MD , Lucas R. Torres MD , Giuseppe D'Ippolito MD, PhD","doi":"10.1053/j.sult.2025.09.007","DOIUrl":"10.1053/j.sult.2025.09.007","url":null,"abstract":"<div><div>Gynecologic neuroendocrine tumors (NETs) are rare, highly aggressive malignancies that can arise in any part of the female reproductive tract, most often in the cervix. Their clinical course is marked by rapid progression, early spread, and limited treatment options, making prompt recognition essential. Diagnosis depends on histopathologic evaluation, supported by immunohistochemistry, while imaging (particularly magnetic resonance) plays a central role in staging, treatment planning, and follow-up, despite often nonspecific appearances. This narrative pictorial review integrates current understanding of histopathologic classification, clinical presentation, and imaging characteristics across modalities, highlighting features that may raise suspicion for these tumors and common diagnostic pitfalls. Representative cases illustrate the spectrum of disease, from localized lesions to widely metastatic presentations. Management typically involves multimodal strategies, with growing interest in targeted and immune-based therapies. By combining clinical, pathologic, and radiologic perspectives, this review aims to enhance awareness and support more timely, accurate diagnosis of these challenging neoplasms.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 440-449"},"PeriodicalIF":1.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sthefane Louise Gomes Nunes MD , Eleonora Salles-Silva MD , Luiza Carvalho Ambrozino MD , Paula Lemos de Castro MD , Mayra Veloso Ayrimoraes Soares MD , Antonio Luis Eiras-Araújo MD, PhD , Daniel Lahan-Martins MD, PhD , Eduardo O. Pacheco MD , Ulysses S. Torres MD, PhD , Giuseppe D’Ippolito MD, PhD , Daniella Braz Parente MD, PhD
{"title":"Rare Non-Tumoral Lesions of the Liver: A Pictorial Review","authors":"Sthefane Louise Gomes Nunes MD , Eleonora Salles-Silva MD , Luiza Carvalho Ambrozino MD , Paula Lemos de Castro MD , Mayra Veloso Ayrimoraes Soares MD , Antonio Luis Eiras-Araújo MD, PhD , Daniel Lahan-Martins MD, PhD , Eduardo O. Pacheco MD , Ulysses S. Torres MD, PhD , Giuseppe D’Ippolito MD, PhD , Daniella Braz Parente MD, PhD","doi":"10.1053/j.sult.2025.09.006","DOIUrl":"10.1053/j.sult.2025.09.006","url":null,"abstract":"<div><div>Rare non-tumoral hepatic lesions encompass a heterogeneous group of vascular, post-traumatic, infectious, inflammatory, and reactive conditions. Diagnosis of these lesions is challenging due to variable imaging appearances and nonspecific clinical presentations, and many lesions are detected incidentally. Correlation with clinical and laboratory findings enhances diagnostic accuracy and supports individualized patient care. Recognition of characteristic imaging patterns is essential to raise diagnostic suspicion and guide appropriate management. This review illustrates the multiphasic CT and MRI features of uncommon hepatic entities (including toxocariasis, hydatid disease, hepatic tuberculosis, hereditary hemorrhagic telangiectasia, regenerative nodular hyperplasia, solitary necrotic nodule, intrahepatic splenosis, and peliosis), emphasizing the imaging hallmarks that facilitate their differentiation.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 390-398"},"PeriodicalIF":1.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter from the Editor","authors":"Gabriela Gayer","doi":"10.1053/j.sult.2025.09.009","DOIUrl":"10.1053/j.sult.2025.09.009","url":null,"abstract":"","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Page 389"},"PeriodicalIF":1.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter from the Guest Editor: Update in head and neck imaging","authors":"Humberto Morales MD","doi":"10.1053/j.sult.2025.09.011","DOIUrl":"10.1053/j.sult.2025.09.011","url":null,"abstract":"","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 5","pages":"Page 343"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145239954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana de Siqueira Bucci MD, Selima Siala MD, Mariana Regina DeFreitas MD, Carolina V. Guimaraes MD
{"title":"What Not to Miss in Fetal Head and Neck MRI: A Pictorial Essay","authors":"Ana de Siqueira Bucci MD, Selima Siala MD, Mariana Regina DeFreitas MD, Carolina V. Guimaraes MD","doi":"10.1053/j.sult.2025.09.001","DOIUrl":"10.1053/j.sult.2025.09.001","url":null,"abstract":"<div><div>Fetal magnetic resonance imaging (MRI) is a safe method of in-utero evaluation of fetal anomalies and a valuable adjunct to prenatal ultrasound. The utilization of rapid sequences reduces the impact of fetal motion and allows for high contrast resolution of fetal structures.A thorough understanding of fetal anatomy and a systematic approach to MRI interpretation are essential for accurate diagnosis of fetal head and neck anomalies. A stepwise structural analysis of fetal head and neck structures includes the evaluation of the facial profile, including maxilla, mandible, nasal bones, and integrity of lip and palate, scalp integrity, skull morphology and proportions, and anatomy of the orbits, nasal passages, choanae, ears and neck (including visualization of the thyroid gland and airway). This approach allows for accurate and effective screening of fetal head and neck anomalies including cleft lip and palate, nasal bone abnormalities, micrognathia, craniosynostosis, skull defects, orbital anomalies, choanal atresia, ear abnormalities, goiter and head and neck masses. MRI assessment further optimizes perinatal management in cases of airway compromise by providing superior visualization of the airway column and its relationship with adjacent structures. This information helps predict a difficult airway and is essential for planning perinatal management and the delivery method, which may include EXIT (Ex-Utero-Intrapartum Treatment) procedure.Early diagnosis remains essential for parental shared decision-making, guiding counseling, and preparing families for the possible perinatal loss, limited life expectancy, or the need for supportive medical care.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 5","pages":"Pages 375-388"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan K. Rigsby MD, Assistant Professor , Olivia A. Thoroughman DO , Courtney M. Tomblinson MD, Associate Professor
{"title":"Review of the Parotid Space: Imaging Features and Diagnostic Pearls","authors":"Ryan K. Rigsby MD, Assistant Professor , Olivia A. Thoroughman DO , Courtney M. Tomblinson MD, Associate Professor","doi":"10.1053/j.sult.2025.09.008","DOIUrl":"10.1053/j.sult.2025.09.008","url":null,"abstract":"<div><div>The parotid space contains several important anatomic structures and can be involved by a variety of pathologies. Herein, we review the imaging anatomy of the parotid space with an emphasis on its clinical relevance. We also review the imaging findings of infectious, inflammatory, congenital, benign, malignant, and nodal pathologies encountered in the parotid space.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 5","pages":"Pages 344-356"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Humberto Morales MD (Associate Professor of Radiology)
{"title":"Imaging of the External Auditory Canal: A Pictorial Review","authors":"Humberto Morales MD (Associate Professor of Radiology)","doi":"10.1053/j.sult.2025.09.010","DOIUrl":"10.1053/j.sult.2025.09.010","url":null,"abstract":"<div><div>The external auditory canal (EAC) is composed by a cartilaginous and an osseous portion. Although it is a pathway, mainly communicating with the tympanic cavity, the EAC is bordering many spaces such as the temporomandibular joint, the temporal bone proper, skull base and the intracranial compartment. Although it can be accessed via clinical exam, there are instances where the view is obstructed, or the clinicians might suspect deeper pathologic involvement or need pre-operative evaluation. CT, MRI and Nuclear Medicine have a role in those cases. Pathologies can include infectious, malignant, epithelial or traumatic lesions, and among others, congenital processes can also affect the external auditory canal. The aim of this review is to familiarize the reader with anatomic landmarks, and to correlate them with important pathologic processes and their imaging findings.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 5","pages":"Pages 357-363"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}