Nathália Gonçalves Dias, Julia de Toledo Mendes, Bruna Andreucci Kozlowski, Daniella Braz Parente, Daniel Lahan Martins, Thiago Franchi Nunes, Matheus Menezes Gomes, Aley Talans, Eduardo Oliveira Pacheco, Ulysses S Torres, Guiseppe D'ippolito
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Abstract
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare tumor, considered a pre-invasive lesion derived from the biliary epithelium. Although it shares similarities with intraductal papillary mucinous neoplasm (IPMN) of the pancreas, only one-third of patients present with mucin hypersecretion. The World Health Organization (WHO) formalized the description of IPNB in 2010 as a "non-invasive biliary papillary or villous neoplasm covering delicate fibrovascular stalks in dilated bile ducts." Despite advancements, literature still lacks multicenter studies on its progression and prognosis. This article reviews the clinical, epidemiological, and radiological features of IPNB, highlighting its recent classifications and key findings, contributing to appropriate management based on a literature review and case examples.
期刊介绍：
Seminars in Ultrasound, CT and MRI is directed to all physicians involved in the performance and interpretation of ultrasound, computed tomography, and magnetic resonance imaging procedures. It is a timely source for the publication of new concepts and research findings directly applicable to day-to-day clinical practice. The articles describe the performance of various procedures together with the authors'' approach to problems of interpretation.
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