Sleep Medicine Reviews最新文献_第3页

What is the nature of sleep and circadian rhythm health on gastrointestinal microbiota? A systematic review of studies in humans 睡眠和昼夜节律健康对胃肠道微生物群的影响是什么？对人类研究的系统回顾。

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-04-01 Epub Date: 2026-02-17 DOI: 10.1016/j.smrv.2026.102256

Magdalena Olson , Dana Withrow , Megan Koelbel , Grace Southworth , Anh Phan , Kenneth P. Wright Jr. , Corrie M. Whisner , Megan E. Petrov

{"title":"What is the nature of sleep and circadian rhythm health on gastrointestinal microbiota? A systematic review of studies in humans","authors":"Magdalena Olson , Dana Withrow , Megan Koelbel , Grace Southworth , Anh Phan , Kenneth P. Wright Jr. , Corrie M. Whisner , Megan E. Petrov","doi":"10.1016/j.smrv.2026.102256","DOIUrl":"10.1016/j.smrv.2026.102256","url":null,"abstract":"<div><div>This systematic review synthesized findings from 41 human studies across the lifespan published between 2016 and 2025 examining associations of multidimensional sleep and circadian rhythm health with the gut microbiome (GM). The studies include experimental and observational designs of generally healthy participants, measuring sleep and circadian dimensions such as duration, quality, insomnia, and circadian disruptions (e.g., shift work). Results suggest sleep truncation, disturbances, and circadian misalignment may be linked to GM composition and function, though results were mixed on microbial diversity. The heterogeneous evidence suggests that the microbial family <em>Oscillospiraceae/Ruminococcaceae</em> is often associated with sleep and circadian metrics, warranting rigorous inquiry of taxa within this family. Functional outputs of the GM were infrequently assessed, but when measured, identified functions in amino acid and fatty acid metabolism, and vitamin, hormone/neurotransmitter, phosphate, short-chain fatty acid, and bile acid pathways. Inconsistencies in findings may reflect differing analytical methods, participants’ age, health status, and lifestyle (e.g., diet, physical activity). Future investigations should prioritize longitudinal and experimental, multi-omics studies to clarify causal pathways and assess interventions, especially in populations with sleep disruption. Findings underscore the potential for sleep and circadian interventions to support GM balance and improve health outcomes.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"86 ","pages":"Article 102256"},"PeriodicalIF":9.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between sleep duration and fluid biomarkers of Alzheimer's disease: A systematic review 睡眠时间与阿尔茨海默病液体生物标志物之间的关系：一项系统综述

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-04-01 Epub Date: 2026-01-23 DOI: 10.1016/j.smrv.2026.102242

Vanessa M. Young , Joy Zeynoun , Agustin Ruiz Laza , Arash Salardini , Christopher R. Frei , Christine Gaspard , Tiffany Kautz , Thiago Macedo e Cordeiro , Matthew P. Pase , Jonathan Gelfond , Jayandra Jung Himali , Antonio L. Teixeira , Sudha Seshadri , Andrée-Ann Baril

{"title":"Association between sleep duration and fluid biomarkers of Alzheimer's disease: A systematic review","authors":"Vanessa M. Young , Joy Zeynoun , Agustin Ruiz Laza , Arash Salardini , Christopher R. Frei , Christine Gaspard , Tiffany Kautz , Thiago Macedo e Cordeiro , Matthew P. Pase , Jonathan Gelfond , Jayandra Jung Himali , Antonio L. Teixeira , Sudha Seshadri , Andrée-Ann Baril","doi":"10.1016/j.smrv.2026.102242","DOIUrl":"10.1016/j.smrv.2026.102242","url":null,"abstract":"<div><div>This systematic review (PROSPERO CRD420246206360) investigated relationships between self-reported or objective sleep duration and fluid biomarkers of Alzheimer's disease pathology and neurodegeneration: cerebrospinal fluid or blood Aβ, p-tau181, t-tau, NfL and GFAP. We searched PubMed, SCOPUS, and CINAHL from inception to September 2024. Twenty studies (n = 12,445) met inclusion criteria (13 cerebrospinal fluid biomarkers [n = 2836]; 7 blood biomarkers [n = 9609]). Study quality was assessed using Newcastle-Ottawa scales. Whereas many studies did not report any associations, some trends emerged: short sleep duration was associated with higher cerebrospinal fluid t-tau and p-tau181 and lower cerebrospinal fluid or blood Aβ42 across multiple studies. Longer sleep duration showed more variable associations, with some suggesting either worse or better biomarker profiles (e.g., higher and lower fluid t-tau, p-tau181, or Aβ42). Two studies investigating non-linear relationships identified U-shaped associations, suggesting both short (≤5–6 h) and long (≥8 h) sleep durations are associated with altered biomarker profiles. The predominantly cross-sectional and high heterogeneity of the available evidence, as well as the relatively small number of studies by individual biomarker (especially for NfL and GFAP) limit conclusions about sleep-biomarker relationships. Future research should investigate emerging blood-based biomarkers and explore temporal associations between sleep duration and Alzheimer's disease biomarker changes.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"86 ","pages":"Article 102242"},"PeriodicalIF":9.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep well, feel well and vice versa? A meta-analysis of daily bidirectional within-person associations between sleep and affect 睡得好，感觉好，反之亦然？一项关于睡眠和情绪之间日常双向关系的元分析

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-04-01 Epub Date: 2026-01-16 DOI: 10.1016/j.smrv.2026.102232

Matthew Bourke , Zoe Harrison , Sally Staton , Kalina Rossa , Simon Smith

{"title":"Sleep well, feel well and vice versa? A meta-analysis of daily bidirectional within-person associations between sleep and affect","authors":"Matthew Bourke , Zoe Harrison , Sally Staton , Kalina Rossa , Simon Smith","doi":"10.1016/j.smrv.2026.102232","DOIUrl":"10.1016/j.smrv.2026.102232","url":null,"abstract":"<div><div>This meta-analysis examines the bidirectional within-person association between sleep and affect using data from 118 studies. Focusing on intensive longitudinal designs such as daily diaries and ecological momentary assessments, this meta-analysis examines how daily variations in sleep, measured via subjective and objective methods, are associated with fluctuations in positive and negative affect. Results show small-to-moderate within-person correlations, with better subjective sleep quality and longer sleep duration predicting improved next-day affect. Conversely, more positive affect and less negative affect during the day were modestly associated with better subjective sleep quality but not total sleep time. The within-person correlations were generally stronger when aspects of sleep were self-reported rather than objectively measured, highlighting the importance of perceived sleep experiences. These findings were largely consistent across age groups and health status, suggesting that the relationship between sleep and affect may be universal. Overall, this study underscores the psychological significance of everyday sleep-affect dynamics.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"86 ","pages":"Article 102232"},"PeriodicalIF":9.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146001835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insomnia among hospitalized inpatients: A systematic review and network meta-analysis 住院患者失眠：系统回顾与网络荟萃分析

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-02-01 Epub Date: 2025-11-22 DOI: 10.1016/j.smrv.2025.102210

Dario Bottignole , Giulia Balella , Matteo Minetti , Luca Gambolò , Francesco Rausa , Giorgio Ughetti , Andrea Melpignano , Marcello Giuseppe Maggio , Liborio Parrino , Carlotta Mutti

{"title":"Insomnia among hospitalized inpatients: A systematic review and network meta-analysis","authors":"Dario Bottignole , Giulia Balella , Matteo Minetti , Luca Gambolò , Francesco Rausa , Giorgio Ughetti , Andrea Melpignano , Marcello Giuseppe Maggio , Liborio Parrino , Carlotta Mutti","doi":"10.1016/j.smrv.2025.102210","DOIUrl":"10.1016/j.smrv.2025.102210","url":null,"abstract":"<div><div>Insomnia affects up to 50% of hospitalized patients and is strongly associated with longer hospital stays and higher mortality rates, especially among vulnerable individuals. Despite its prevalence, it's often overlooked in clinical practice and research. Our systematic review analyzed and compared pharmacological interventions for insomnia in hospitalized patients. We searched five major databases for randomized controlled trials published before January 2024. A total of 29 trials (1913 patients, mean age 58.4 ± 9.66) were finally included. Different drug classes were evaluated, including benzodiazepines, Z-drugs, melatonin receptor agonists, antidepressants, antihistamines, alpha-2 adrenergic agonists, and dietary supplements. We conducted a network meta-analysis on drugs' efficacy across subjective sleep quality, sleep latency, total sleep duration, and nocturnal awakenings. Notably, only a minority of studies focused on fragile populations, such as geriatric and critically ill patients. Results are also discussed according to potential moderating factors (i.e., gender, age, admission setting). Our review provides a framework for the pharmacologic treatment of insomnia disorder in inpatients. Differences in study methodologies limit the generalizability of findings, highlighting the urgent need for standardized research to fill existing gaps. We therefore propose a concise protocol to guide the design of future studies on this clinically important topic.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"85 ","pages":"Article 102210"},"PeriodicalIF":9.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145625383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bridging artificial intelligence and sleep medicine: current evidence, open challenges, and future directions 连接人工智能和睡眠医学：目前的证据、公开的挑战和未来的方向

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-02-01 Epub Date: 2026-01-18 DOI: 10.1016/j.smrv.2026.102237

Hanwen Bi , Wen Liu , Masoud Tahmasian

引用次数: 0

Implementing strategies to address the global burden of insomnia 实施解决全球失眠负担的战略

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-02-01 Epub Date: 2025-11-22 DOI: 10.1016/j.smrv.2025.102209

Adam V. Benjafield , Emerson M. Wickwire

引用次数: 0

Handling Editor: Monica AndersenA global perspective of parent engagement with digital sleep health interventions for young children: A scoping review 家长参与幼儿数字睡眠健康干预的全球视角：范围审查

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-02-01 Epub Date: 2025-12-13 DOI: 10.1016/j.smrv.2025.102226

Alicia Chung , Laurel Deaton , Jennifer Miller , Ashley Nechyba , Jenny Liu , Menessa Metayer , Tayla von Ash , Michelle Thompson , Shayla K. Shorter , Dorice Vieira , Azizi A. Seixas , Girardin Jean-Louis

{"title":"Handling Editor: Monica AndersenA global perspective of parent engagement with digital sleep health interventions for young children: A scoping review","authors":"Alicia Chung , Laurel Deaton , Jennifer Miller , Ashley Nechyba , Jenny Liu , Menessa Metayer , Tayla von Ash , Michelle Thompson , Shayla K. Shorter , Dorice Vieira , Azizi A. Seixas , Girardin Jean-Louis","doi":"10.1016/j.smrv.2025.102226","DOIUrl":"10.1016/j.smrv.2025.102226","url":null,"abstract":"<div><h3>Introduction</h3><div>We examined the landscape of early childhood sleep health interventions that utilized digital tools designed for parents to improve sleep health outcomes during early childhood, (ages 3–8).</div></div><div><h3>Methods</h3><div>We performed a scoping review of peer-reviewed articles published from inception to April 2025 from the following databases: PubMed, Embase, Web of Science, MEDLINE, Cochrane Library, Engineering Village, Global Health, citation searching, and others. Two medical science librarians conducted the extensive literature search, with strategies detailed at [<span><span>osf.io/74hba</span><svg><path></path></svg></span>]. This study was guided by the implementation science outcomes framework.</div></div><div><h3>Results</h3><div>Twenty-one articles met the final inclusion criteria. Included studies reported clinical sleep, behavioral and/or implementation science outcomes. Implementation science outcomes primarily focused on acceptability, appropriateness and feasibility of pediatric digital sleep and family-based tools. Mobile apps were most prominently used, followed by websites and telehealth. Websites contributed to improved child sleep duration, sleep onset, sleep efficiency, daytime sleepiness and reduced night wakings. Mobile apps reported the aforementioned child sleep outcomes, as well as improvements in parent mental health and daytime functioning.</div></div><div><h3>Conclusions</h3><div>Digital sleep health tools have the potential to ameliorate sleep problems in young children. Digital interventions may improve sleep and wellbeing in the family unit.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"85 ","pages":"Article 102226"},"PeriodicalIF":9.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145883592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial intelligence and sleep medicine II: A scoping review of applications, advancements, and future directions 人工智能和睡眠医学II：应用、进展和未来方向的范围审查。

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-02-01 Epub Date: 2025-11-28 DOI: 10.1016/j.smrv.2025.102212

Haitham Jahrami , Waqar Husain , Khaled Trabelsi , Thomas Penzel , Max Hirshkowitz , Javad Razjouyan , Ahmed S. BaHammam , Amir Sharafkhaneh

{"title":"Artificial intelligence and sleep medicine II: A scoping review of applications, advancements, and future directions","authors":"Haitham Jahrami , Waqar Husain , Khaled Trabelsi , Thomas Penzel , Max Hirshkowitz , Javad Razjouyan , Ahmed S. BaHammam , Amir Sharafkhaneh","doi":"10.1016/j.smrv.2025.102212","DOIUrl":"10.1016/j.smrv.2025.102212","url":null,"abstract":"<div><h3>Background</h3><div>Artificial intelligence (AI) has rapidly advanced in sleep medicine, offering innovative solutions for sleep disorder management. The integration of AI technologies presents unprecedented opportunities to address longstanding challenges in diagnosis, monitoring, and treatment.</div></div><div><h3>Methods</h3><div>This scoping review summarizes current AI applications in sleep medicine following PRISMA-ScR. A comprehensive search was conducted across various databases from inception to 2024, following PRISMA-ScR guidelines. Eligible studies included original AI research, systematic reviews, and meta-analyses focusing on sleep medicine.</div></div><div><h3>Results</h3><div>AI models for obstructive sleep apnea (OSA) detection demonstrated accuracy between 85 % and 99 % in controlled settings, with outlier up to 99.9 %. Deep learning approaches for sleep staging and quality assessment match human expert performance. AI applications have extended to other disorders like insomnia and narcolepsy. Wearable technologies and non-contact sensors enable continuous monitoring outside laboratory settings, with some achieving sensitivity >96 % and specificity >97 % for OSA detection. Significant real-world validation gaps persist.</div></div><div><h3>Conclusions</h3><div>While AI shows transformative potential in sleep medicine, implementation challenges remain. Future research should prioritize multicenter validation, ethical governance, and culturally inclusive AI frameworks to ensure safe and equitable clinical translation. Addressing ethical considerations and standardizing methodological reporting are essential for widespread adoption of these technologies in clinical practice.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"85 ","pages":"Article 102212"},"PeriodicalIF":9.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep, cognition, and electrophysiology: Intersecting pathways in childhood cancer 睡眠、认知和电生理：儿童癌症的交叉通路。

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-02-01 Epub Date: 2025-11-22 DOI: 10.1016/j.smrv.2025.102205

Andrea Sanchez-Corzo , Zachary Loschinskey , Miguel Navarrete , Catalina A. Saini Ferron , Pankaj Pandey , Jesyin Lai , Belinda N. Mandrell , Zachary R. Abramson , Valerie McLaughlin Crabtree , Ranganatha Sitaram

{"title":"Sleep, cognition, and electrophysiology: Intersecting pathways in childhood cancer","authors":"Andrea Sanchez-Corzo , Zachary Loschinskey , Miguel Navarrete , Catalina A. Saini Ferron , Pankaj Pandey , Jesyin Lai , Belinda N. Mandrell , Zachary R. Abramson , Valerie McLaughlin Crabtree , Ranganatha Sitaram","doi":"10.1016/j.smrv.2025.102205","DOIUrl":"10.1016/j.smrv.2025.102205","url":null,"abstract":"<div><div>Survivors of pediatric cancer are at high risk of long-term cognitive dysfunction. This problem is exacerbated as this population often reports poor sleep quality, which can negatively affect well-being. Sleep-related brain activity is known to influence cognitive development by regulating memory consolidation and cognitive functioning. However, the differences in sleep-related brain activity between healthy controls and pediatric cancer survivors are unclear. This review examines how sleep disturbances and cognitive impairments converge in survivors of childhood cancer, and proposes electrophysiology as a possible mechanistic bridge between these domains. We synthesize what is known from the general population and pediatric samples, highlight the critical need to investigate electrophysiological anomalies in pediatric cancer survivors, and suggest that neuromodulation techniques such as transcranial direct stimulation, transcranial magnetic stimulation, and sensory stimulation may be viable therapeutic interventions to enhance both sleep quality and cognitive function once possible anomalies are characterized in this population. Our review emphasizes the need for additional research to understand the complex relationship between sleep and cognition in pediatric cancer survivors to improve patient care and quality of life.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"85 ","pages":"Article 102205"},"PeriodicalIF":9.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep apnea and substance use: a meta-analysis 睡眠呼吸暂停和物质使用：一项荟萃分析。

IF 9.7 1区医学

Sleep Medicine Reviews Pub Date : 2026-02-01 Epub Date: 2026-01-07 DOI: 10.1016/j.smrv.2025.102228

Sibylle Mauries , Benjamin Rolland , Justine Frija-Masson , Marie-Pia d’Ortho , Sébastien Catoire , Feriel Zehani , Guillaume Davido , Michel Lejoyeux , Pierre A. Geoffroy

{"title":"Sleep apnea and substance use: a meta-analysis","authors":"Sibylle Mauries , Benjamin Rolland , Justine Frija-Masson , Marie-Pia d’Ortho , Sébastien Catoire , Feriel Zehani , Guillaume Davido , Michel Lejoyeux , Pierre A. Geoffroy","doi":"10.1016/j.smrv.2025.102228","DOIUrl":"10.1016/j.smrv.2025.102228","url":null,"abstract":"<div><h3>Introduction</h3><div>Sleep apnea and substance use disorders appear to interact bidirectionally, negatively influencing each other. Obstructive sleep apnea syndrome (OSA) seems particularly prevalent among substance users.</div></div><div><h3>Methods</h3><div>This meta-analysis aims to evaluate the impact of the most commonly used substances (alcohol, tobacco, cannabis, opioids, and cocaine) on the apnea-hypopnea index (AHI) by comparing the mean AHI scores between users and non-users.</div></div><div><h3>Results</h3><div>3784 articles were identified from the PubMed search, and 28 studies were included in the meta-analysis. We found a higher AHI among alcohol users (SMD: 0.46, 95 % CI [0.21–0.71] (z = 3.62; p < 0.001)) and a higher prevalence of central sleep apnea among opioid users (SMD: 0.44 95 % CI 0.24–0.64] (z = 4.37; p < 0.001)). The AHI was also elevated among tobacco users, although this difference was not statistically significant. Regarding moderators effects, sex may influence alcohol's impact, while both age and sex could affect the relationship between opioids and AHI. No studies compared the AHI of cocaine users to non-users, and only one study comparing the AHI of cannabis users to non-users were found.</div></div><div><h3>Conclusion</h3><div>This study highlights the importance of diagnosing and managing sleep apnea in patients with substance use, in order to improve addiction prognosis through specific treatment approaches.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"85 ","pages":"Article 102228"},"PeriodicalIF":9.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146020457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0