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Sleep alterations in major depressive disorder and insomnia disorder: A network meta-analysis of polysomnographic studies
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2025-01-15 DOI: 10.1016/j.smrv.2025.102048
Caterina Leitner , Francesca Dalle Piagge , Tijana Tomic , Federica Nozza , Elisabetta Fasiello , Vincenza Castronovo , Luigi De Gennaro , Chiara Baglioni , Luigi Ferini-Strambi , Andrea Galbiati
{"title":"Sleep alterations in major depressive disorder and insomnia disorder: A network meta-analysis of polysomnographic studies","authors":"Caterina Leitner ,&nbsp;Francesca Dalle Piagge ,&nbsp;Tijana Tomic ,&nbsp;Federica Nozza ,&nbsp;Elisabetta Fasiello ,&nbsp;Vincenza Castronovo ,&nbsp;Luigi De Gennaro ,&nbsp;Chiara Baglioni ,&nbsp;Luigi Ferini-Strambi ,&nbsp;Andrea Galbiati","doi":"10.1016/j.smrv.2025.102048","DOIUrl":"10.1016/j.smrv.2025.102048","url":null,"abstract":"<div><div>Major depressive disorder (MDD) and Insomnia disorder (ID) are characterized by sleep alterations. To define their polysomnographic profiles, we conducted a Network Meta-Analysis comparing MDD and ID patients <em>versus</em> healthy controls (HCs). The literature search, conducted from 2008 up to January 2023 and following PRISMA guidelines, covered PubMed, Web of Science, Scopus, and Embase databases. We addressed publication bias using funnel plot asymmetry inspection and Egger’s test, evaluated statistical heterogeneity with I<sup>2</sup>, and local and global inconsistencies with the separate indirect from direct evidence method and Q between designs, respectively. Pairwise meta-analyses employed a fixed-effects model, while network analysis utilized a random-effect approach. We evaluated 86 ID and 17 MDD studies, comparing sleep parameters for 636 MDDs <em>versus</em> 491 HCs, and 3661 IDs <em>versus</em> 2792 HCs. The network meta-analysis reported that patients with MDD have greater rapid eye movement (REM) sleep duration and REMs density, and lower REM sleep latency compared to IDs. ID patients instead exhibited lower total sleep time and time in bed, and greater wake after sleep onset and non-REM sleep stage 3 than MDD patients. This work emphasized sleep depth and continuity alterations in both MDD and ID, with major involvement of REM sleep in MDD.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102048"},"PeriodicalIF":11.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive behavioral therapy for insomnia across the spectrum of alcohol use disorder: A systematic review and meta-analysis 认知行为疗法治疗酒精中毒性失眠症:系统回顾和荟萃分析。
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2025-01-11 DOI: 10.1016/j.smrv.2025.102049
Cagdas Türkmen , Carlotta L. Schneider , Wolfgang Viechtbauer , Ingeborg Bolstad , Subhajit Chakravorty , Mary Beth Miller , Håvard Kallestad , Guro W. Angenete , Anna F. Johann , Bernd Feige , Kai Spiegelhalder , Dieter Riemann , Øystein Vedaa , Ståle Pallesen , Elisabeth Hertenstein
{"title":"Cognitive behavioral therapy for insomnia across the spectrum of alcohol use disorder: A systematic review and meta-analysis","authors":"Cagdas Türkmen ,&nbsp;Carlotta L. Schneider ,&nbsp;Wolfgang Viechtbauer ,&nbsp;Ingeborg Bolstad ,&nbsp;Subhajit Chakravorty ,&nbsp;Mary Beth Miller ,&nbsp;Håvard Kallestad ,&nbsp;Guro W. Angenete ,&nbsp;Anna F. Johann ,&nbsp;Bernd Feige ,&nbsp;Kai Spiegelhalder ,&nbsp;Dieter Riemann ,&nbsp;Øystein Vedaa ,&nbsp;Ståle Pallesen ,&nbsp;Elisabeth Hertenstein","doi":"10.1016/j.smrv.2025.102049","DOIUrl":"10.1016/j.smrv.2025.102049","url":null,"abstract":"<div><div>Insomnia is prevalent among patients with alcohol use disorder (AUD), potentially undermining treatment and increasing the risk of relapse. Cognitive behavioral therapy for insomnia (CBT-I) is the recommended first-line treatment for insomnia, but its efficacy is not well-characterized in patients across the spectrum of AUD. The aim of this meta-analysis was to quantify the effectiveness of CBT-I in improving insomnia severity and alcohol-related outcomes in adults with heavy alcohol use and/or varying levels of AUD severity and comorbid insomnia. MEDLINE, Cochrane Library, PsycINFO and ClinicalTrials.gov were systematically searched (up to February 2024) to retrieve randomized controlled trials (RCTs). Multilevel meta-analyses were conducted to estimate mean differences over time in insomnia severity, measured using the Insomnia Severity Index (ISI), as well as in alcohol craving and alcohol-related psychosocial problems between CBT-I and control groups. For the number of heavy-drinking/abstinent days, incidence rate ratios were estimated. Risk of bias was assessed using the Risk of Bias 2 (RoB 2) tool. Eight RCTs encompassing 426 adults (68.78 % men) were included. Compared with control conditions, CBT-I resulted in a large reduction of insomnia severity post-treatment [estimated ISI reduction = <strong>−</strong>5.51, 95% CI (<strong>−</strong>7.13 to −3.90)], which was maintained at 1-to-3-month [7 studies; estimate = −4.39, 95% CI (<strong>−</strong>6.08 to −2.70)], and 6-month follow-up [4 studies; estimate = −4.55, 95% CI (<strong>−</strong>6.77 to −2.33)]. Alcohol-related outcomes were reported less consistently, and no significant differences were found. The included trials were judged to have a low or moderate overall risk of bias for the assessment of all outcomes. CBT-I effectively reduces insomnia severity across the spectrum of AUD, supporting wide implementation in AUD prevention and treatment settings.</div></div><div><h3>PROSPERO registration number</h3><div>CRD42023464612.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102049"},"PeriodicalIF":11.2,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AI-enhanced imagery rehearsal therapy: A novel approach to treating nightmare disorder 人工智能增强的意象排练疗法:一种治疗噩梦障碍的新方法。
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-12-17 DOI: 10.1016/j.smrv.2024.102046
Michal Kahn
{"title":"AI-enhanced imagery rehearsal therapy: A novel approach to treating nightmare disorder","authors":"Michal Kahn","doi":"10.1016/j.smrv.2024.102046","DOIUrl":"10.1016/j.smrv.2024.102046","url":null,"abstract":"","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102046"},"PeriodicalIF":11.2,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychopathology and NREM sleep parasomnias: A systematic review 精神病理学和非快速眼动睡眠异象:系统综述。
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-12-15 DOI: 10.1016/j.smrv.2024.102043
Tijana Tomic , Samantha Mombelli , Stan Oana , Luigi Ferini-Strambi , Andrea Raballo , Mauro Manconi , Andrea Galbiati , Anna Castelnovo
{"title":"Psychopathology and NREM sleep parasomnias: A systematic review","authors":"Tijana Tomic ,&nbsp;Samantha Mombelli ,&nbsp;Stan Oana ,&nbsp;Luigi Ferini-Strambi ,&nbsp;Andrea Raballo ,&nbsp;Mauro Manconi ,&nbsp;Andrea Galbiati ,&nbsp;Anna Castelnovo","doi":"10.1016/j.smrv.2024.102043","DOIUrl":"10.1016/j.smrv.2024.102043","url":null,"abstract":"<div><div>Non-rapid eye movement (NREM) sleep parasomnias are abnormal motor and/or emotional behaviors originating from \"deep\" slow-wave sleep and with a multifactorial origin. The relationship between NREM parasomnias and psychopathology has been a topic of ongoing debate, but a comprehensive and systematic perspective has been lacking. This systematic review, conducted according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA-P) guidelines, aims to fill this gap in the literature.</div><div>Databases including PubMed, Scopus, Embase, and Web of Science were searched from their inception until March 2024. Only studies written in English were included. We selected case-control studies that reported either psychopathological or neurodevelopmental data in NREM sleep parasomnias, or NREM sleep parasomnia data across different mental disorders, across children and adults.</div><div>Our review found that psychopathological and neurodevelopmental issues are common in NREM parasomnias, with a higher prevalence in affected patients compared to non-affected individuals. Additionally, NREM parasomnias are more common among patients with various psychopathological conditions than in the general population. Medications did not significantly bias these results. These findings suggest that psychopathological aspects should become a core focus of research and treatment strategies for NREM parasomnias.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102043"},"PeriodicalIF":11.2,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pre-and post-migration factors associated with sleep health among Latin American immigrants in the United States: A systematic review 移民前后与美国拉丁美洲移民睡眠健康相关的因素:一项系统综述
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-12-13 DOI: 10.1016/j.smrv.2024.102047
Isamar M. Almeida, Linda Thompson, Alvaro Rivera, Emily Feldman, Ateka A. Contractor, Martinque Jones, Danica C. Slavish
{"title":"Pre-and post-migration factors associated with sleep health among Latin American immigrants in the United States: A systematic review","authors":"Isamar M. Almeida,&nbsp;Linda Thompson,&nbsp;Alvaro Rivera,&nbsp;Emily Feldman,&nbsp;Ateka A. Contractor,&nbsp;Martinque Jones,&nbsp;Danica C. Slavish","doi":"10.1016/j.smrv.2024.102047","DOIUrl":"10.1016/j.smrv.2024.102047","url":null,"abstract":"<div><div>Immigrants face unique challenges and stressors before leaving their country of origin and upon arrival to their host country, all of which may impair their sleep health. We synthesized the literature on pre-and-post migration factors predicting sleep outcomes among foreign-born Latin American immigrants to the United States. Following PRISMA guidelines, we searched three electronic databases: PubMed, PsycINFO, and Web of Science. We supplemented our search using Google Scholar and by manually reviewing reference lists from all included studies and four reviews on similar topics. Out of 2581 references screened, 12 peer-reviewed studies met our inclusion criteria. All studies but one were quantitative. Most were cross-sectional, consisted of adults, relied on self-reported measures of sleep, and had a low risk of bias. Acculturation stress, perceived discrimination and racism, working multiple jobs, as well as poor physical and mental health were the most consistent predictors of poorer sleep health in this population. Being born in Mexico and greater biculturalism were predictors of better sleep health. We discuss gaps in the literature, highlight opportunities for future research, and argue for a more comprehensive examination of how pre-migration experiences impact post-migration sleep health.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102047"},"PeriodicalIF":11.2,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conditions of sleep restoration after smoking cessation: A systematic review
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-12-09 DOI: 10.1016/j.smrv.2024.102041
Sibylle Mauries , Benjamin Rolland , Maia Mallevays , Sébastien Catoire , Feriel Zehani , Karine Sauvage , Guillaume Davido , Michel Lejoyeux , Pierre A. Geoffroy
{"title":"Conditions of sleep restoration after smoking cessation: A systematic review","authors":"Sibylle Mauries ,&nbsp;Benjamin Rolland ,&nbsp;Maia Mallevays ,&nbsp;Sébastien Catoire ,&nbsp;Feriel Zehani ,&nbsp;Karine Sauvage ,&nbsp;Guillaume Davido ,&nbsp;Michel Lejoyeux ,&nbsp;Pierre A. Geoffroy","doi":"10.1016/j.smrv.2024.102041","DOIUrl":"10.1016/j.smrv.2024.102041","url":null,"abstract":"<div><div>Previous studies have highlighted the prevalence of disordered sleep in smokers, with subjective sleep complaints and alterations of sleep architecture, including a reduction in slow-wave sleep (SWS). These findings raise questions regarding the impact of smoking cessation and withdrawal on sleep.</div><div>This review aims to assess the impact of smoking cessation on sleep by taking into account objective and subjective methods of assessment. The selected articles compared both participants’ sleep before and after smoking cessation, and the sleep characteristics of patients who had relapsed compared to those who had maintained abstinence. The selected studies presented results for patients who did not receive any cessation treatment, or who received either medication-based or psychotherapeutic treatments.</div><div>In patients undergoing smoking cessation without NRT, the N1 stage was reduced in those maintaining abstinence for 6 months, while rapid eye movement (REM) sleep was reduced only in those who relapsed. No significant difference in SWS was observed between patients who maintained abstinence and those who relapsed. Regarding the use of NRT, one study observed that long-term nicotine patches, compared to short-acting patches, were associated with an increase in SWS.</div><div>Despite heterogeneous results, sleep alterations appear to persist for the first few weeks of withdrawal and predict relapses. Finally, although limited, there seems to be a restoration of sleep for patients using NRT.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102041"},"PeriodicalIF":11.2,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A meta-analytic investigation of the effect of sleep deprivation on inhibitory control 睡眠剥夺对抑制控制影响的荟萃分析研究。
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-12-08 DOI: 10.1016/j.smrv.2024.102042
Sze Yinn Choong , Jamie E.M. Byrne , Sean P.A. Drummond , Maris Rispoli-Yovanovic , Andrew Jones , Jarrad A.G. Lum , Petra K. Staiger
{"title":"A meta-analytic investigation of the effect of sleep deprivation on inhibitory control","authors":"Sze Yinn Choong ,&nbsp;Jamie E.M. Byrne ,&nbsp;Sean P.A. Drummond ,&nbsp;Maris Rispoli-Yovanovic ,&nbsp;Andrew Jones ,&nbsp;Jarrad A.G. Lum ,&nbsp;Petra K. Staiger","doi":"10.1016/j.smrv.2024.102042","DOIUrl":"10.1016/j.smrv.2024.102042","url":null,"abstract":"<div><div>Sleep deprivation may have a deleterious effect on inhibitory control; however, this effect is not consistent across studies. To arrive at an overall estimate of the relationship between sleep deprivation and inhibitory control, this report used meta-analysis to summarise the magnitude of the effects of sleep deprivation on inhibitory control as measured by the Go/No-Go and Stop Signal Tasks. These are two widely used tasks in the literature. A systematic search of four databases (APAPsycINFO, Medline, CINAHL and Embase) from their inception to November 2023 identified 24 studies involving 712 healthy individuals. Separate random-effects models were used to estimate the effect size of sleep deprivation on performance in these tasks. The meta-analysis revealed a moderate negative effect of sleep deprivation on inhibitory control in both the Go/No-Go and Stop Signal Tasks. Given the importance of inhibitory control in everyday behaviour, future research should investigate the neural and neurophysiological mechanisms underlying this relationship and explore its impact in clinical populations.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102042"},"PeriodicalIF":11.2,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new chapter: Embracing the role of Editor-in-Chief of Sleep Medicine Reviews 一个新的篇章:接受《睡眠医学评论》主编的角色。
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-12-07 DOI: 10.1016/j.smrv.2024.102044
Monica Levy Andersen
{"title":"A new chapter: Embracing the role of Editor-in-Chief of Sleep Medicine Reviews","authors":"Monica Levy Andersen","doi":"10.1016/j.smrv.2024.102044","DOIUrl":"10.1016/j.smrv.2024.102044","url":null,"abstract":"","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102044"},"PeriodicalIF":11.2,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of depression in pediatric patients with diagnosed or at high risk for obstructive sleep apnea: A systematic review with meta-analysis 诊断为阻塞性睡眠呼吸暂停或处于高风险的儿童患者的抑郁症患病率:一项系统综述与荟萃分析
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-12-04 DOI: 10.1016/j.smrv.2024.102040
Lara Pereira , Ellen Song , Cristine M. Stefani , Carlos Flores-Mir , Graziela De Luca Canto , Camila Pacheco-Pereira
{"title":"Prevalence of depression in pediatric patients with diagnosed or at high risk for obstructive sleep apnea: A systematic review with meta-analysis","authors":"Lara Pereira ,&nbsp;Ellen Song ,&nbsp;Cristine M. Stefani ,&nbsp;Carlos Flores-Mir ,&nbsp;Graziela De Luca Canto ,&nbsp;Camila Pacheco-Pereira","doi":"10.1016/j.smrv.2024.102040","DOIUrl":"10.1016/j.smrv.2024.102040","url":null,"abstract":"<div><div>Obstructive sleep apnea (OSA) may increase the risk of depression through various hypothesized mechanisms. Studies regarding this relationship with children are limited. This systematic review aims to assess the prevalence of depression in pediatric patients with OSA. Five electronic databases, grey literature, and reference lists of included studies were systematically searched. Studies reporting the prevalence of depression, as described by the Diagnostic and Statistical Manual of Mental Disorders (DSM), psychiatric evaluation or other validated screening measures, in children with OSA diagnosed by polysomnography (PSG), or at high risk for OSA based on positive scores on other validated measures were included. The risk of bias was performed using the Joanna Briggs Institute (JBI) Checklist for cross-sectional studies. Six studies from three countries and over 2300 pediatric patients were included. This meta-analysis showed an overall 28 % prevalence of depression among children with OSA or at high risk for OSA, which is almost two-fold higher than among children without OSA (controls). Overall, this meta-analysis suggests that around one out of every four children with or at high risk for OSA could have depression, and one in 10 children if OSA has been confirmed by PSG. Screening of OSA in pediatric patients with symptoms of depression and vice versa, screening of depressive symptoms in children with suspected or confirmed OSA, may be valuable areas of focus for multidisciplinary preventative care to optimize psychiatric treatment.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102040"},"PeriodicalIF":11.2,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adverse events in patients with obstructive sleep apnea undergoing procedural sedation in ambulatory settings: An updated systematic review and meta-analysis 阻塞性睡眠呼吸暂停患者在门诊环境中接受程序性镇静的不良事件:一项最新的系统回顾和荟萃分析。
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-11-28 DOI: 10.1016/j.smrv.2024.102029
Felicia Ceban , Naomi Abayomi , Aparna Saripella , Jennita Ariaratnam , Glen Katsnelson , Ellene Yan , Marina Englesakis , Tong J. Gan , Girish P. Joshi , Frances Chung
{"title":"Adverse events in patients with obstructive sleep apnea undergoing procedural sedation in ambulatory settings: An updated systematic review and meta-analysis","authors":"Felicia Ceban ,&nbsp;Naomi Abayomi ,&nbsp;Aparna Saripella ,&nbsp;Jennita Ariaratnam ,&nbsp;Glen Katsnelson ,&nbsp;Ellene Yan ,&nbsp;Marina Englesakis ,&nbsp;Tong J. Gan ,&nbsp;Girish P. Joshi ,&nbsp;Frances Chung","doi":"10.1016/j.smrv.2024.102029","DOIUrl":"10.1016/j.smrv.2024.102029","url":null,"abstract":"<div><h3>Objective</h3><div>Patients with obstructive sleep apnea (OSA) may be at increased risk for adverse events during procedural sedation, however, there remains a gap in the literature quantifying these risks. This systematic review and meta-analysis aimed to evaluate the risk of peri-procedural adverse events in OSA patients undergoing procedural sedation in ambulatory settings, compared to those without OSA.</div></div><div><h3>Methods</h3><div>Four databases were systematically searched for studies published from January 1, 2011 to January 4, 2024. The inclusion criteria were: adult patients with OSA undergoing procedural sedation in ambulatory settings, peri-procedural adverse events reported, and control group included. The primary outcome was the incidence of peri-procedural adverse events amongst patients with vs without OSA.</div></div><div><h3>Results</h3><div>Nineteen studies (27,973 patients) were included. The odds of respiratory adverse events were significantly increased for patients with OSA (OR 1.65, 95 % CI 1.03–2.66, P = 0.04). Furthermore, the odds of requiring an airway maneuver/intervention were significantly greater for patients with OSA (OR 3.28, 95 % CI 1.43–7.51, P = 0.005). The odds of cardiovascular adverse events were not significantly increased for patients with OSA.</div></div><div><h3>Conclusion</h3><div>Patients with OSA undergoing procedural sedation in ambulatory settings had 1.7-fold greater odds of respiratory adverse events and 3.3-fold greater odds of requiring airway maneuvers/interventions.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102029"},"PeriodicalIF":11.2,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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