Sleep Medicine Reviews最新文献

筛选
英文 中文
The effect of physical exercise interventions on insomnia: A systematic review and meta-analysis 体育锻炼干预对失眠的影响:系统回顾与荟萃分析。
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-05-09 DOI: 10.1016/j.smrv.2024.101948
Anuschka Riedel , Fee Benz , Peter Deibert , Friedrich Barsch , Lukas Frase , Anna F. Johann , Dieter Riemann , Bernd Feige
{"title":"The effect of physical exercise interventions on insomnia: A systematic review and meta-analysis","authors":"Anuschka Riedel ,&nbsp;Fee Benz ,&nbsp;Peter Deibert ,&nbsp;Friedrich Barsch ,&nbsp;Lukas Frase ,&nbsp;Anna F. Johann ,&nbsp;Dieter Riemann ,&nbsp;Bernd Feige","doi":"10.1016/j.smrv.2024.101948","DOIUrl":"10.1016/j.smrv.2024.101948","url":null,"abstract":"<div><p>6–10 % of Europeans suffer from chronic insomnia. They have a higher risk to develop mental and cardiovascular diseases. Treatment of insomnia primarily recommended by the European guideline is cognitive behavioral therapy for insomnia (CBT-I). A quarter of patients treated with CBT-I do not respond sufficiently. The objective of this paper is to examine the influence of exercise interventions on insomnia by conducting a systematic review and meta-analysis. A database search was conducted, including randomized controlled trials (RCT) in which participants had received a diagnosis of insomnia or experienced symptoms thereof. Exercise interventions had to meet the definition of the World Health Organization (WHO), and their implementation was reported according to the FITT (Frequency, Intensity, Time and Type) principle. There was an inactive control and subjective or objective sleep parameters as outcomes. Nineteen studies were included. Results showed a significant improvement for objective (standardized mean difference, SMD = 0.37; confidence interval, CI = [0.17; 0.57]) as well as subjective (SMD = 0.90; CI = [0.61; 1.19]) sleep parameters. Meta-regression showed that the effect increased with intensity of intervention, mean age of participants and percentage of females, but showed high heterogeneity across studies. These results suggest great potential for treating insomnia. Conducting larger trials is advisable to provide precise recommendations.</p></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"76 ","pages":"Article 101948"},"PeriodicalIF":10.5,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1087079224000522/pdfft?md5=8a041dda0bb0b35dc9f5c96537a25c19&pid=1-s2.0-S1087079224000522-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140945998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring hypoglossal nerve stimulation therapy for obstructive sleep apnea: A comprehensive review of clinical and physiological upper airway outcomes 探索针对阻塞性睡眠呼吸暂停的舌下神经刺激疗法:上气道临床和生理结果的全面回顾
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-05-09 DOI: 10.1016/j.smrv.2024.101947
Marie-Michèle Serghani , Clemens Heiser , Alan R. Schwartz , Jason Amatoury
{"title":"Exploring hypoglossal nerve stimulation therapy for obstructive sleep apnea: A comprehensive review of clinical and physiological upper airway outcomes","authors":"Marie-Michèle Serghani ,&nbsp;Clemens Heiser ,&nbsp;Alan R. Schwartz ,&nbsp;Jason Amatoury","doi":"10.1016/j.smrv.2024.101947","DOIUrl":"10.1016/j.smrv.2024.101947","url":null,"abstract":"<div><p>Obstructive sleep apnea (OSA) is a chronic disorder characterized by recurrent episodes of upper airway collapse during sleep, which can lead to serious health issues like cardiovascular disease and neurocognitive impairments. While positive airway pressure serves as the standard treatment, intolerance in some individuals necessitates exploration of alternative therapies. Hypoglossal nerve stimulation (HGNS) promises to mitigate OSA morbidity by stimulating the tongue muscles to maintain airway patency. However, its effectiveness varies, prompting research for optimization. This review summarizes the effects of HGNS on upper airway obstruction from human and animal studies. It examines physiological responses including critical closing pressure, maximal airflow, nasal and upper airway resistance, compliance, stiffness, and geometry. Interactions among these parameters and discrepant findings in animal and human studies are explored. Additionally, the review summarizes the impact of HGNS on established OSA metrics, such as the apnea-hypopnea index, oxygen desaturation index, and sleep arousals. Various therapeutic modalities, including selective unilateral or bilateral HGNS, targeted unilateral HGNS, and whole unilateral or bilateral HGNS, are discussed. This review consolidates our understanding of HGNS mechanisms, fostering exploration of under-investigated outcomes and approaches to drive advancements in HGNS therapy.</p></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"76 ","pages":"Article 101947"},"PeriodicalIF":10.5,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141047453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary on Castelnovo et al the parasomnia defense in sleep-related homicide 对 Castelnovo 等人的评论:与睡眠有关的凶杀案中的寄生虫辩护
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-05-08 DOI: 10.1016/j.smrv.2024.101952
John Rumbold , Ian Morrison , Renata Riha
{"title":"Commentary on Castelnovo et al the parasomnia defense in sleep-related homicide","authors":"John Rumbold ,&nbsp;Ian Morrison ,&nbsp;Renata Riha","doi":"10.1016/j.smrv.2024.101952","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.101952","url":null,"abstract":"","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"76 ","pages":"Article 101952"},"PeriodicalIF":10.5,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140918379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Individualized approaches to pediatric chronic insomnia: Advancing precision medicine in sleep disorders 小儿慢性失眠症的个性化治疗方法:推进睡眠障碍的精准医疗
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-05-07 DOI: 10.1016/j.smrv.2024.101946
Oliviero Bruni , Marco Angriman , Silvia Miano , Lourdes M. DelRosso , Karen Spruyt , Maria P. Mogavero , Raffaele Ferri
{"title":"Individualized approaches to pediatric chronic insomnia: Advancing precision medicine in sleep disorders","authors":"Oliviero Bruni ,&nbsp;Marco Angriman ,&nbsp;Silvia Miano ,&nbsp;Lourdes M. DelRosso ,&nbsp;Karen Spruyt ,&nbsp;Maria P. Mogavero ,&nbsp;Raffaele Ferri","doi":"10.1016/j.smrv.2024.101946","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.101946","url":null,"abstract":"<div><p>The manifestations of chronic insomnia undergo age-related changes. In younger infants and children, behavioral insomnia emerges as the most prevalent form and typically responds to behavioral interventions. However, distinct clusters of clinical presentations suggest the presence of various phenotypes, potentially implicating the primary involvement of specific neurotransmitters. These conceptualizations, coupled with genetic studies on pleiotropy and polygenicity, may aid in identifying individuals at risk of persistent insomnia into adulthood and shed light on novel treatment options. In school-age children, the predominant presentation is sleep-onset insomnia, often linked with nighttime fears, anxiety symptoms, poor sleep hygiene, limit-setting issues, and inadequate sleep duration. The manifestations of insomnia in adolescence correlate with the profound changes occurring in sleep architecture, circadian rhythms, and homeostatic processes. The primary symptoms during adolescence include delayed sleep onset, sleep misperception, persistent negative thoughts about sleep, and physiological hyperarousal—paralleling features observed in adult insomnia. An approach centered on distinct presentations may provide a framework for precision-based treatment options. Enhanced comprehension of insomnia’s manifestations across diverse developmental stages can facilitate accurate assessment. Efforts to subtype insomnia in childhood align with this objective, potentially guiding the selection of appropriate treatments tailored to individual neurobiological, clinical, and familial features.</p></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"76 ","pages":"Article 101946"},"PeriodicalIF":10.5,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140910298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bright light therapy in cancer: Evidence for future research and therapy 癌症中的强光疗法:未来研究和治疗的证据
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-05-07 DOI: 10.1016/j.smrv.2024.101945
Nancy S. Redeker
{"title":"Bright light therapy in cancer: Evidence for future research and therapy","authors":"Nancy S. Redeker","doi":"10.1016/j.smrv.2024.101945","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.101945","url":null,"abstract":"","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"75 ","pages":"Article 101945"},"PeriodicalIF":10.5,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140906455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep assessment using EEG-based wearables – A systematic review 使用脑电图可穿戴设备进行睡眠评估 - 系统综述
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-05-07 DOI: 10.1016/j.smrv.2024.101951
C.J. de Gans , P. Burger , E.S. van den Ende , J. Hermanides , P.W.B. Nanayakkara , R.J.B.J. Gemke , F. Rutters , D.J. Stenvers
{"title":"Sleep assessment using EEG-based wearables – A systematic review","authors":"C.J. de Gans ,&nbsp;P. Burger ,&nbsp;E.S. van den Ende ,&nbsp;J. Hermanides ,&nbsp;P.W.B. Nanayakkara ,&nbsp;R.J.B.J. Gemke ,&nbsp;F. Rutters ,&nbsp;D.J. Stenvers","doi":"10.1016/j.smrv.2024.101951","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.101951","url":null,"abstract":"<div><p>Polysomnography (PSG) is the reference standard of sleep measurement, but is burdensome for the participant and labor intensive. Affordable electroencephalography (EEG)-based wearables are easy to use and are gaining popularity, yet selecting the most suitable device is a challenge for clinicians and researchers. In this systematic review, we aim to provide a comprehensive overview of available EEG-based wearables to measure human sleep. For each wearable, an overview will be provided regarding validated population and reported measurement properties. A systematic search was conducted in the databases OVID MEDLINE, Embase.com and CINAHL. A machine learning algorithm (ASReview) was utilized to screen titles and abstracts for eligibility. In total, 60 papers were selected, covering 34 unique EEG-based wearables. Feasibility studies indicated good tolerance, high compliance, and success rates. The 42 included validation studies were conducted across diverse populations and showed consistently high accuracy in sleep staging detection. Therefore<strong>,</strong> the recent advancements in EEG-based wearables show great promise as alternative for PSG and for at-home sleep monitoring. Users should consider factors like user-friendliness, comfort, and costs, as these devices vary in features and pricing, impacting their suitability for individual needs.</p></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"76 ","pages":"Article 101951"},"PeriodicalIF":10.5,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1087079224000558/pdfft?md5=5757a5c8010e5bba8fe2f2b638b96be6&pid=1-s2.0-S1087079224000558-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140947562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sensory aspects of restless legs syndrome: Clinical, neurophysiological and neuroimaging prospectives 不宁腿综合征的感官方面:临床、神经生理学和神经影像学展望。
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-05-07 DOI: 10.1016/j.smrv.2024.101949
Elena Antelmi , Maria P. Mogavero , Giuseppe Lanza , Sandy M. Cartella , Luigi Ferini-Strambi , Giuseppe Plazzi , Raffaele Ferri , Michele Tinazzi
{"title":"Sensory aspects of restless legs syndrome: Clinical, neurophysiological and neuroimaging prospectives","authors":"Elena Antelmi ,&nbsp;Maria P. Mogavero ,&nbsp;Giuseppe Lanza ,&nbsp;Sandy M. Cartella ,&nbsp;Luigi Ferini-Strambi ,&nbsp;Giuseppe Plazzi ,&nbsp;Raffaele Ferri ,&nbsp;Michele Tinazzi","doi":"10.1016/j.smrv.2024.101949","DOIUrl":"10.1016/j.smrv.2024.101949","url":null,"abstract":"<div><p>Restless Legs Syndrome (RLS) is a complex sensorimotor disorder, classified among the sleep-related movement disorders. Although sensory symptoms appear as key features of the disorder, they are still poorly characterized from a clinical perspective and conceptualized from a pathophysiological point of view. In this review, we aim to describe the clinical and functional substrates of RLS, focusing mainly on its sensory symptoms and on their neurophysiological and anatomical correlates. Knowledge of both subjective sensory symptoms and objective sensory signs are still controversial. Current data also indicate that the sensory component of RLS seems to be subserved by anomalies of sensorimotor integration and by mechanism of central sensitization. Overall, electrophysiological findings highlight the involvement of multiple generators in the pathogenesis of RLS, eventually resulting in an increased nervous system excitability and/or alterations in inhibition within the somatosensory and nociceptive pathways. Structural and functional neuroimaging data show the involvement of several crucial areas and circuits, among which the thalamus appears to play a pivotal role. A holistic approach looking at brain connectivity, structural or functional abnormalities, and their interplay with molecular vulnerability and neurotransmitter alterations is warranted to disentangle the complex framework of RLS.</p></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"76 ","pages":"Article 101949"},"PeriodicalIF":10.5,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140945891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lamentations in the night: A systematic review on catathrenia 黑夜中的哀歌catathrenia 系统综述
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-05-06 DOI: 10.1016/j.smrv.2024.101944
Quentin Martel , Jean-Baptiste Maranci , Carole Philippe , Isabelle Arnulf
{"title":"Lamentations in the night: A systematic review on catathrenia","authors":"Quentin Martel ,&nbsp;Jean-Baptiste Maranci ,&nbsp;Carole Philippe ,&nbsp;Isabelle Arnulf","doi":"10.1016/j.smrv.2024.101944","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.101944","url":null,"abstract":"<div><p>Catathrenia is a loud expiratory moan during sleep that is a social embarrassment and is sometimes confused with central apnea on polysomnography. It affects about 4% of adults, but cases are rarely referred to sleep centers. Catathrenia affects males and females, children and adults, who are usually young and thin. A “typical” catathrenia begins with a deep inhalation, followed by a long, noisy exhalation, then a short, more pronounced exhalation, followed by another deep inhalation, often accompanied by arousal. The many harmonics of the sound indicate that it is produced by the vocal cords. It is often repeated in clusters, especially during REM sleep and at the end of the night. It does not disturb the sleepers, but their neighbors, and is associated with excessive daytime sleepiness in one-third of cases. The pathophysiology and treatment of typical catathrenia are still unknown. Later, a more atypical catathrenia was described, consisting of episodes of short (2 s), regular, semi-continuous expiratory moans during NREM sleep (mainly in stages N1 and N2) and REM sleep, often in people with mild upper airway obstruction. This atypical catathrenia is more commonly reduced by positive airway pressure and mandibular advancement devices that promote vertical opening.</p></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"75 ","pages":"Article 101944"},"PeriodicalIF":10.5,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140880088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep apnea and stroke: A dynamic duo 睡眠呼吸暂停与中风活力二重奏
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-05-01 DOI: 10.1016/j.smrv.2024.101943
Antonio Culebras
{"title":"Sleep apnea and stroke: A dynamic duo","authors":"Antonio Culebras","doi":"10.1016/j.smrv.2024.101943","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.101943","url":null,"abstract":"","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"75 ","pages":"Article 101943"},"PeriodicalIF":10.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140950533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating pharmacological treatments for excessive daytime sleepiness in obstructive sleep apnea: A comprehensive network meta-analysis and systematic review 评估针对阻塞性睡眠呼吸暂停患者白天过度嗜睡的药物治疗:综合网络荟萃分析和系统综述
IF 10.5 1区 医学
Sleep Medicine Reviews Pub Date : 2024-04-30 DOI: 10.1016/j.smrv.2024.101934
Seyed Sina Neshat , Afshin Heidari , Mario Henriquez-Beltran , Kripa Patel , Brendon Colaco , Vichaya Arunthari , Alejandra Yu Lee Mateus , Joseph Cheung , Gonzalo Labarca
{"title":"Evaluating pharmacological treatments for excessive daytime sleepiness in obstructive sleep apnea: A comprehensive network meta-analysis and systematic review","authors":"Seyed Sina Neshat ,&nbsp;Afshin Heidari ,&nbsp;Mario Henriquez-Beltran ,&nbsp;Kripa Patel ,&nbsp;Brendon Colaco ,&nbsp;Vichaya Arunthari ,&nbsp;Alejandra Yu Lee Mateus ,&nbsp;Joseph Cheung ,&nbsp;Gonzalo Labarca","doi":"10.1016/j.smrv.2024.101934","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.101934","url":null,"abstract":"<div><p>Obstructive sleep apnea (OSA) is associated with excessive daytime sleepiness (EDS). Pharmacotherapy offers a potential treatment approach for EDS in OSA patients. This systematic review and meta-analysis aimed to assess the efficacy and safety of pharmacological interventions for alleviating EDS in patients with OSA. Following PRISMA guidelines, we included randomized controlled trials investigating pharmacological treatments for EDS in adult OSA until August 2023. We conducted meta-analysis, subgroup, and meta-regression analyses using a random effects model. Finally, a network meta-analysis synthesized direct and indirect evidence, followed by a comprehensive safety analysis. We included 32 articles in the meta-analysis (n = 3357). Pharmacotherapy showed a significant improvement in the Epworth Sleepiness Scale (ESS) score (Mean Difference (MD) −2.73, (95 % Confidence Interval (CI) [−3.25, −2.20], p &lt; 0.01) and Maintenance of Wakefulness Test (MWT) score (MD 6.00 (95 % CI [2.66, 9.33] p &lt; 0.01). Solriamfetol, followed by Pitolisant and modafinil, exhibited the greatest ESS reduction, while Danavorexton, followed by Solriamfetol and MK-7288, had the strongest impact on MWT. MK-7288 had the most total adverse events (AEs), followed by Danavorexton and armodafinil. Pharmacological Interventions significantly alleviate EDS in OSA patients but with heterogeneity across medications. Treatment decisions should involve a personalized assessment of patient factors and desired outcomes.</p></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"76 ","pages":"Article 101934"},"PeriodicalIF":10.5,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140950459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信