Sleep Medicine Reviews最新文献

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A meta-analytic investigation of the effect of sleep deprivation on inhibitory control.
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-12-08 DOI: 10.1016/j.smrv.2024.102042
Sze Yinn Choong, Jamie E M Byrne, Sean P A Drummond, Maris Rispoli-Yovanovic, Andrew Jones, Jarrad A G Lum, Petra K Staiger
{"title":"A meta-analytic investigation of the effect of sleep deprivation on inhibitory control.","authors":"Sze Yinn Choong, Jamie E M Byrne, Sean P A Drummond, Maris Rispoli-Yovanovic, Andrew Jones, Jarrad A G Lum, Petra K Staiger","doi":"10.1016/j.smrv.2024.102042","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.102042","url":null,"abstract":"<p><p>Sleep deprivation may have a deleterious effect on inhibitory control; however, this effect is not consistent across studies. To arrive at an overall estimate of the relationship between sleep deprivation and inhibitory control, this report used meta-analysis to summarise the magnitude of the effects of sleep deprivation on inhibitory control as measured by the Go/No-Go and Stop Signal Tasks. These are two widely used tasks in the literature. A systematic search of four databases (APAPsycINFO, Medline, CINAHL and Embase) from their inception to November 2023 identified 24 studies involving 712 healthy individuals. Separate random-effects models were used to estimate the effect size of sleep deprivation on performance in these tasks. The meta-analysis revealed a moderate negative effect of sleep deprivation on inhibitory control in both the Go/No-Go and Stop Signal Tasks. Given the importance of inhibitory control in everyday behaviour, future research should investigate the neural and neurophysiological mechanisms underlying this relationship and explore its impact in clinical populations.</p>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"102042"},"PeriodicalIF":11.2,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of depression in pediatric patients with diagnosed or at high risk for obstructive sleep apnea: A systematic review with meta-analysis.
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-12-04 DOI: 10.1016/j.smrv.2024.102040
Lara Pereira, Ellen Song, Cristine M Stefani, Carlos Flores-Mir, Graziela De Luca Canto, Camila Pacheco-Pereira
{"title":"Prevalence of depression in pediatric patients with diagnosed or at high risk for obstructive sleep apnea: A systematic review with meta-analysis.","authors":"Lara Pereira, Ellen Song, Cristine M Stefani, Carlos Flores-Mir, Graziela De Luca Canto, Camila Pacheco-Pereira","doi":"10.1016/j.smrv.2024.102040","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.102040","url":null,"abstract":"<p><p>Obstructive sleep apnea (OSA) may increase the risk of depression through various hypothesized mechanisms. Studies regarding this relationship with children are limited. This systematic review aims to assess the prevalence of depression in pediatric patients with OSA. Five electronic databases, grey literature, and reference lists of included studies were systematically searched. Studies reporting the prevalence of depression, as described by the Diagnostic and Statistical Manual of Mental Disorders (DSM), psychiatric evaluation or other validated screening measures, in children with OSA diagnosed by polysomnography (PSG), or at high risk for OSA based on positive scores on other validated measures were included. The risk of bias was performed using the Joanna Briggs Institute (JBI) Checklist for cross-sectional studies. Six studies from three countries and over 2300 pediatric patients were included. This meta-analysis showed an overall 28 % prevalence of depression among children with OSA or at high risk for OSA, which is almost two-fold higher than among children without OSA (controls). Overall, this meta-analysis suggests that around one out of every four children with or at high risk for OSA could have depression, and one in 10 children if OSA has been confirmed by PSG. Screening of OSA in pediatric patients with symptoms of depression and vice versa, screening of depressive symptoms in children with suspected or confirmed OSA, may be valuable areas of focus for multidisciplinary preventative care to optimize psychiatric treatment.</p>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"102040"},"PeriodicalIF":11.2,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adverse events in patients with obstructive sleep apnea undergoing procedural sedation in ambulatory settings: An updated systematic review and meta-analysis.
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-11-28 DOI: 10.1016/j.smrv.2024.102029
Felicia Ceban, Naomi Abayomi, Aparna Saripella, Jennita Ariaratnam, Glen Katsnelson, Ellene Yan, Marina Englesakis, Tong J Gan, Girish P Joshi, Frances Chung
{"title":"Adverse events in patients with obstructive sleep apnea undergoing procedural sedation in ambulatory settings: An updated systematic review and meta-analysis.","authors":"Felicia Ceban, Naomi Abayomi, Aparna Saripella, Jennita Ariaratnam, Glen Katsnelson, Ellene Yan, Marina Englesakis, Tong J Gan, Girish P Joshi, Frances Chung","doi":"10.1016/j.smrv.2024.102029","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.102029","url":null,"abstract":"<p><strong>Objective: </strong>Patients with obstructive sleep apnea (OSA) may be at increased risk for adverse events during procedural sedation, however, there remains a gap in the literature quantifying these risks. This systematic review and meta-analysis aimed to evaluate the risk of peri-procedural adverse events in OSA patients undergoing procedural sedation in ambulatory settings, compared to those without OSA.</p><p><strong>Methods: </strong>Four databases were systematically searched for studies published from January 1, 2011 to January 4, 2024. The inclusion criteria were: adult patients with OSA undergoing procedural sedation in ambulatory settings, peri-procedural adverse events reported, and control group included. The primary outcome was the incidence of peri-procedural adverse events amongst patients with vs without OSA.</p><p><strong>Results: </strong>Nineteen studies (27,973 patients) were included. The odds of respiratory adverse events were significantly increased for patients with OSA (OR 1.65, 95 % CI 1.03-2.66, P = 0.04). Furthermore, the odds of requiring an airway maneuver/intervention were significantly greater for patients with OSA (OR 3.28, 95 % CI 1.43-7.51, P = 0.005). The odds of cardiovascular adverse events were not significantly increased for patients with OSA.</p><p><strong>Conclusion: </strong>Patients with OSA undergoing procedural sedation in ambulatory settings had 1.7-fold greater odds of respiratory adverse events and 3.3-fold greater odds of requiring airway maneuvers/interventions.</p>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"102029"},"PeriodicalIF":11.2,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What you believe is what you get? A systematic review examining how beliefs and attitudes about sleep are associated with sleep duration in non-clinical samples
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-11-23 DOI: 10.1016/j.smrv.2024.102032
Spencer A. Nielson , Julia T. Boyle , Natalie D. Dautovich , Joseph M. Dzierzewski
{"title":"What you believe is what you get? A systematic review examining how beliefs and attitudes about sleep are associated with sleep duration in non-clinical samples","authors":"Spencer A. Nielson ,&nbsp;Julia T. Boyle ,&nbsp;Natalie D. Dautovich ,&nbsp;Joseph M. Dzierzewski","doi":"10.1016/j.smrv.2024.102032","DOIUrl":"10.1016/j.smrv.2024.102032","url":null,"abstract":"<div><div>A burgeoning area of research is investigating whether beliefs and attitudes about sleep are associated with sleep duration in individuals without clinical conditions (e.g., insomnia, depression, anxiety, chronic pain). This review sought to examine and synthesize the extant research in non-clinical samples. A systematic review of the literature following PRISMA guidelines was conducted between March 2024 and May 2024, with 2204 studies screened. Study quality was assessed using NIH's Quality Assessment Tool for Cohort and Cross-Sectional Studies and NIH's Quality Assessment Tool for Controlled Intervention Studies. Seventeen articles met eligibility criteria. All studies were classified as “fair” or “poor” quality. Studies generally demonstrated that more favorable attitudes and beliefs were associated with appropriate sleep duration. Specific beliefs related to sleep may be differentially associated with sleep duration. Preliminary evidence demonstrated that demographic factors may modify this association. Favorable attitudes toward sleep may be associated with more appropriate sleep duration among individuals without clinical conditions. However, the quality of the extant research was rated poorly, demonstrating a need for additional, higher quality studies. Future studies should consider this relationship while considering demographic factors as this may have important implications for public sleep health efforts.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102032"},"PeriodicalIF":11.2,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In defence of the arousal and sleep displacement hypotheses: Considering the role of automatic processes in pre-sleep technology use 为唤醒和睡眠转移假说辩护:考虑自动过程在睡前使用技术中的作用
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-11-22 DOI: 10.1016/j.smrv.2024.102025
Vanessa M. Hill, Sally A. Ferguson, Amanda L. Rebar, Grace E. Vincent
{"title":"In defence of the arousal and sleep displacement hypotheses: Considering the role of automatic processes in pre-sleep technology use","authors":"Vanessa M. Hill,&nbsp;Sally A. Ferguson,&nbsp;Amanda L. Rebar,&nbsp;Grace E. Vincent","doi":"10.1016/j.smrv.2024.102025","DOIUrl":"10.1016/j.smrv.2024.102025","url":null,"abstract":"","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"79 ","pages":"Article 102025"},"PeriodicalIF":11.2,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Continuing excellence and a fond farewell
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-11-21 DOI: 10.1016/j.smrv.2024.102033
Michael V. Vitiello (Professor Emeritus)
{"title":"Continuing excellence and a fond farewell","authors":"Michael V. Vitiello (Professor Emeritus)","doi":"10.1016/j.smrv.2024.102033","DOIUrl":"10.1016/j.smrv.2024.102033","url":null,"abstract":"","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"79 ","pages":"Article 102033"},"PeriodicalIF":11.2,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142747720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Motor cortex excitability in restless legs syndrome: A systematic review and insights into pathophysiology via transcranial magnetic stimulation
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-11-20 DOI: 10.1016/j.smrv.2024.102027
Giuseppe Lanza , Maria Paola Mogavero , Raffaele Ferri , Tapas Pani
{"title":"Motor cortex excitability in restless legs syndrome: A systematic review and insights into pathophysiology via transcranial magnetic stimulation","authors":"Giuseppe Lanza ,&nbsp;Maria Paola Mogavero ,&nbsp;Raffaele Ferri ,&nbsp;Tapas Pani","doi":"10.1016/j.smrv.2024.102027","DOIUrl":"10.1016/j.smrv.2024.102027","url":null,"abstract":"<div><div>Restless Legs Syndrome (RLS) is a neurological disorder characterized by a complex and only partially understood pathophysiology. Numerous studies have investigated motor cortex excitability in RLS using transcranial magnetic stimulation (TMS), but a comprehensive systematic review assessing their methodological quality and synthesizing their findings is lacking. A systematic search of PubMed focused on various TMS parameters, including resting and active motor thresholds, motor evoked potential characteristics, contralateral and ipsilateral silent periods, and multiple measures of intracortical inhibition and facilitation. The quality of each study was evaluated using custom checklists and the modified Newcastle-Ottawa Quality Assessment Scale. Out of the studies screened, 21 (comprising 319 RLS patients and 278 healthy controls) met the inclusion criteria. Despite considerable variability in TMS methodologies—such as differences in the muscles tested, interstimulus intervals, testing timing, and the potential confounding effects of medications—a consistent finding was a reduction in short-interval intracortical inhibition, a key indicator of central inhibitory GABAergic activity. Additionally, altered post-exercise facilitation and delayed facilitation suggest abnormal motor plasticity in RLS patients. These findings suggest that despite the methodological heterogeneity, TMS abnormalities may play a crucial role in the pathophysiology of RLS. In this context, RLS symptoms are likely to originate at different levels within a complex neural network, ultimately leading to altered, possibly transient and circadian, excitability in a multifaceted neurophysiological system. While further rigorous research and reproducible evidence are needed, these insights may contribute to the identification of new diagnostic markers and the development of innovative therapeutic strategies for RLS.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"79 ","pages":"Article 102027"},"PeriodicalIF":11.2,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of alcohol on subsequent sleep in healthy adults: A systematic review and meta-analysis.
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-11-19 DOI: 10.1016/j.smrv.2024.102030
Carissa Gardiner, Jonathon Weakley, Louise M Burke, Gregory D Roach, Charli Sargent, Nirav Maniar, Minh Huynh, Dean J Miller, Andrew Townshend, Shona L Halson
{"title":"The effect of alcohol on subsequent sleep in healthy adults: A systematic review and meta-analysis.","authors":"Carissa Gardiner, Jonathon Weakley, Louise M Burke, Gregory D Roach, Charli Sargent, Nirav Maniar, Minh Huynh, Dean J Miller, Andrew Townshend, Shona L Halson","doi":"10.1016/j.smrv.2024.102030","DOIUrl":"https://doi.org/10.1016/j.smrv.2024.102030","url":null,"abstract":"<p><p>Alcohol is commonly consumed prior to bedtime with the belief that it facilitates sleep. This systematic review and meta-analysis investigated the impact of alcohol on the characteristics of night-time sleep, with the intent to identify the influence of the dose and timing of alcohol intake. A systematic search of the literature identified 27 studies for inclusion in the analysis. Changes in sleep architecture were observed, including a delay in the onset of rapid eye movement (REM) sleep and a reduction in the duration of REM sleep. A dose-response relationship was identified such that disruptions to REM sleep occurred following consumption of a low dose of alcohol (≤0.50 g∙kg<sup>-1</sup> or approximately two standard drinks) and progressively worsened with increasing doses of alcohol. Reductions in sleep onset latency and latency to deep sleep (i.e., non-rapid eye movement stage three (N3)) were only observed following the consumption of a high dose of alcohol (≥0.85∙g kg<sup>-1</sup> or approximately five standard drinks). The effect of alcohol on the remaining characteristics of sleep could not be determined, with large uncertainty observed in the effect on total sleep time, sleep efficiency, and wake after sleep onset. The results of the present study suggest that a low dose of alcohol will negatively impact (i.e., reduce) REM sleep. It appears that high doses of alcohol may shorten sleep onset latency, however this likely exacerbates subsequent REM sleep disruption. Future work on personal and environmental factors that affect alcohol metabolism, and any differential effects of alcohol due to sex is encouraged.</p>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"102030"},"PeriodicalIF":11.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circadian immunometabolism: A future insight for targeted therapy in cancer 昼夜节律免疫代谢:洞察癌症靶向治疗的未来
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-11-19 DOI: 10.1016/j.smrv.2024.102031
Manendra Singh Tomar , Mohit , Ashok Kumar , Ashutosh Shrivastava
{"title":"Circadian immunometabolism: A future insight for targeted therapy in cancer","authors":"Manendra Singh Tomar ,&nbsp;Mohit ,&nbsp;Ashok Kumar ,&nbsp;Ashutosh Shrivastava","doi":"10.1016/j.smrv.2024.102031","DOIUrl":"10.1016/j.smrv.2024.102031","url":null,"abstract":"<div><div>Circadian rhythms send messages to regulate the sleep-wake cycle in living beings, which, regulate various biological activities. It is well known that altered sleep-wake cycles affect host metabolism and significantly deregulate the host immunity. The dysregulation of circadian-related genes is critical for various malignancies. One of the hallmarks of cancer is altered metabolism, the effects of which spill into surrounding microenvironments. Here, we review the emerging literature linking the circadian immunometabolic axis to cancer. Small metabolites are the products of various metabolic pathways, that are usually perturbed in cancer. Genes that regulate circadian rhythms also regulate host metabolism and control metabolite content in the tumor microenvironment. Immune cell infiltration into the tumor site is critical to perform anticancer functions, and altered metabolite content affects their trafficking to the tumor site. A compromised immune response in the tumor microenvironment aids cancer cell proliferation and immune evasion, resulting in metastases. The role of circadian rhythms in these processes is largely overlooked and demands renewed attention in the search for targets against cancer growth and spread. The precision medicine approach requires targeting the circadian immune metabolism in cancer.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"80 ","pages":"Article 102031"},"PeriodicalIF":11.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142723540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proposing a definition for sleep disorders: An epistemological review 提出睡眠障碍的定义:认识论回顾。
IF 11.2 1区 医学
Sleep Medicine Reviews Pub Date : 2024-11-18 DOI: 10.1016/j.smrv.2024.102028
Christophe Gauld , Jerome C. Wakefield , Jean-Arthur Micoulaud-Franchi
{"title":"Proposing a definition for sleep disorders: An epistemological review","authors":"Christophe Gauld ,&nbsp;Jerome C. Wakefield ,&nbsp;Jean-Arthur Micoulaud-Franchi","doi":"10.1016/j.smrv.2024.102028","DOIUrl":"10.1016/j.smrv.2024.102028","url":null,"abstract":"<div><div>To establish an overarching definition of what constitutes a sleep disorder, it is essential to know which health conditions should be included in the classifications of sleep disorders and to better distinguish the normal from the pathological in sleep medicine. This would bring together several professional organizations in their understanding of this hitherto heterogeneous concept. However, no consensus regarding a general definition of a sleep disorder currently exists. We explore two of the main frameworks used in medical epistemology that could be used to define sleep disorders rigorously: harmful dysfunction analysis (HDA) and symptom network theory. For each framework, we detail the conceptual background, the method for applying it to the establishment of a general definition of a sleep disorder, the application to main sleep disorders of the ICSD-3-TR (with an emphasis on insomnia disorder) and a discussion of the main aspects of these two general definitions in the context of sleep medicine. The complementarity between the two definitions could then be considered as an “epistemic hub” which could serve to clarify the debate about what sleep disorders are, so that our understanding of them and their clinical management improve.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"79 ","pages":"Article 102028"},"PeriodicalIF":11.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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