Social Psychiatry and Psychiatric Epidemiology最新文献

{"title":"A comparison of pathways to care in at-risk mental states and first episode psychosis: a mental health electronic clinical records analysis in the East of England, UK.","authors":"Rhiannon Murden, Sophie M Allan, Jo Hodgekins, Sheri Oduola","doi":"10.1007/s00127-025-02833-3","DOIUrl":"https://doi.org/10.1007/s00127-025-02833-3","url":null,"abstract":"<p><strong>Purpose: </strong>Delays in treatment for individuals experiencing early signs of psychosis are associated with poorer outcomes. Few people presenting with first episode psychosis (FEP) access early intervention in psychosis (EIP) services during the prodromal stage. In this study, we compared pathways to care (PtC) in people with At-Risk Mental States (ARMS) and FEP and explored the sociodemographic factors associated with accessing EIP during ARMS or FEP.</p><p><strong>Methods: </strong>Sociodemographic and PtC data were collected from the Cambridgeshire and Peterborough NHS Foundation Trust (CPFT) Research Database. All individuals referred and accepted to CPFT EIP services as either ARMS or FEP between 1st April 2018 and 31st October 2019 (N = 158) were included.</p><p><strong>Results: </strong>There was strong evidence that ARMS patients accessing EIP were younger and were less likely to have a minority ethnic status than FEP patients. In terms of PtC, ARMS patients had fewer numbers of contacts, were less likely to be referred via the acute services, less likely to be involuntarily admitted and had reduced family involvement in their help-seeking. No differences were identified between ARMS and FEP in terms of living circumstances, area-level deprivation, urbanicity, employment status, duration of PtC, or police involvement in PtC.</p><p><strong>Conclusion: </strong>Our findings highlight that disparities exist between ARMS and FEP patients in terms of sociodemographic and PtC characteristics. Further research is required to replicate these findings and investigate the effectiveness of interventions to encourage and facilitate access to EIP at an earlier stage to improve outcomes.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age, period, and cohort trends of substance poisoning, alcohol-related disease, and suicide deaths in Australia, 1980-2019.","authors":"Chrianna Bharat, Ria E Hopkins, Mark Chambers, Louisa Degenhardt, Amy Peacock, Michael Farrell, Wing See Yuen, Nicola Man, Natasa Gisev","doi":"10.1007/s00127-024-02749-4","DOIUrl":"10.1007/s00127-024-02749-4","url":null,"abstract":"<p><strong>Purpose: </strong>Deaths due to substance poisoning, alcohol-related disease, and suicide pose a critical public health issue, and have been categorized as \"deaths of despair\" in the US. Whether these deaths represent a distinct phenomenon requires exploration, particularly in other countries.</p><p><strong>Methods: </strong>This retrospective observational study examines age-period-cohort trends of (combined and cause-specific) substance poisoning, alcohol-related disease, and suicide deaths among Australians aged ≥15-years that occurred between 1980 and 2019 and compares trends between males and females.</p><p><strong>Results: </strong>Combined mortality rates were initially (1980-1999) relatively stable, reflecting a reduction in alcohol-related disease deaths offset by an increase in substance poisoning deaths. A decline (2000-2006) and subsequent increase (2007-2019) in combined rates were primarily attributable to corresponding changes in both substance poisoning and suicide deaths among males. Distinct age-period-cohort trends were observed between cause of death sub-types, with net drifts: increasing for male (net drift [95% CI]: 3.33 [2.84, 3.83]) and female (2.58 [2.18, 2.98]) substance poisoning deaths; decreasing among male alcohol-related disease (- 1.46 [- 1.75, - 1.16]) and suicide deaths (- 0.52[- 0.69, - 0.36]); and remaining relatively stable for female alcohol-related disease (- 0.28 [- 0.66, 0.09]) and suicide deaths (- 0.25 [- 0.52, 0.01]).</p><p><strong>Conclusions: </strong>Although combined age-specific trends were relatively stable over the study period, different and distinct patterns were observed within cause-specific deaths, challenging the notion that these causes of death represent a distinct epidemiological phenomenon. These data indicate a critical need to review the appropriateness of guidance for clinical practice, prevention strategies, and policy initiatives aimed at preventing future deaths.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"693-703"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142047413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between negative life events and suicidal behavior in adolescents: roles of core self-evaluation, depression and gender.","authors":"Yue Li, Xi Shen, Jin-Liang Wang","doi":"10.1007/s00127-024-02725-y","DOIUrl":"10.1007/s00127-024-02725-y","url":null,"abstract":"<p><strong>Purpose: </strong>Negative life events are essential proximal factors that may induce suicidal behavior in adolescents, but the mechanisms connecting this link remain to further explored. The present study aimed to investigate the relationship between negative life events (NLEs) and adolescents' suicidal behavior, and the roles of core self-evaluation, depression and gender playing between them.</p><p><strong>Methods: </strong>Using the whole-group sampling approach, 5296 Chinese adolescents (51.5% males, Mean_age = 12.93) took part in this cross-sectional study in September 2021 and completed a battery of surveys including NLEs, suicidal behavior, CSE (core self-evaluation) and depression. Logistic regression and latent structural equation models were used to test the direct and indirect effects between NLEs and suicide behavior with multi-group path analysis, gender differences in this serial mediating effect were also tested.</p><p><strong>Results: </strong>After controlling for age and gender, NLEs were directly associated with adolescents' suicidal behavior. CSE and depression played significant serial mediating effects in this relationship. Moreover, significant gender differences were obtained in these serial mediating pathways, with stronger effects in girls.</p><p><strong>Conclusion: </strong>Integrating the environmental, individual cognitive and emotional factors, our findings would be helpful in understanding the mechanism of these antecedents on adolescents' suicide behavior, which has specific practical significance for preventing and reducing suicidal behavior.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"673-684"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Change in incidents of suicidal acts after intervention on a bridge in South Korea.","authors":"Sangsoo Shin, Jane Pirkis, Matthew J Spittal, Lay San Too, Angela Clapperton","doi":"10.1007/s00127-024-02744-9","DOIUrl":"10.1007/s00127-024-02744-9","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate whether two novel interventions on a bridge - a Video Incident Detection System (VIDS) and spinning bar barriers - have an impact on suicidal behaviour on the bridge.</p><p><strong>Methods: </strong>A total of 146 suicidal acts were retrieved for analyses; 108 interventions before suicidal acts, 35 suicide deaths and 3 suicide attempts. Incident rate ratios (IRR) were calculated to estimate the change in incident rate associated with implementation of the two interventions: VIDS and the spinning bar 2-metre high barrier.</p><p><strong>Results: </strong>The results of the Poisson regression showed that the rate of suicide deaths, after installation the VIDS, did not change significantly (IRR: 1.23, 95% Confidence Interval [95% CI]: 0.59-2.56), although the rate of intervened suicidal acts increased (IRR: 2.40, 95% CI: 1.65-3.47). The results showed that subsequent spinning bar installation resulted in a decrease in the incident rate of intervened suicidal acts (IRR: 0.37, 95% CI: 0.25-0.57) as well as suicide deaths (IRR: 0.23, 95% CI: 0.07-0.71). Comparison of the period when both interventions were in place with the period with no interventions indicated a reduction in suicide deaths (IRR: 0.28, 95% CI: 0.10-0.82), but no change in intervened suicidal acts (IRR: 0.90, 95% CI: 0.59-1.38).</p><p><strong>Conclusion: </strong>The rate of suicide death decreased after the installation of the spinning bar barrier but not after the implementation of VIDS alone. Our findings reinforce that restricting access to means is a highly effective way of preventing suicide on bridges and that spinning bars may be a helpful way to design barriers.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"685-691"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141908167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Durational effect of ambient air pollution on hospital admissions of schizophrenia: a time series analysis.","authors":"Xiaolan Huang, Chun Zhou, Xianyan Tang, Yuhua Wei, Dongmei Li, Bing Shen, Qinggui Lei, Qian Zhou, Jun Lan, Yanli Qin, Li Su, Jianxiong Long","doi":"10.1007/s00127-025-02831-5","DOIUrl":"https://doi.org/10.1007/s00127-025-02831-5","url":null,"abstract":"<p><strong>Background: </strong>Schizophrenia may be exacerbated by ambient air pollution. In this study, we aim to explore the association of air pollution with hospital admission for schizophrenia in Liuzhou, China.</p><p><strong>Methods: </strong>The daily concentration of air pollutants was gathered from an average of seven fixed monitoring sites in Liuzhou, while the daily admission data for schizophrenia was received from The Guangxi Zhuang Autonomous Region Brain Hospital. A Poisson generalized linear regression model in conjunction with a distributed lag nonlinear model was utilized to quantify the exposure-lag-response connection between ambient air pollution and schizophrenia hospitalization. The stratification analysis was then carried out by age, gender, and season.</p><p><strong>Results: </strong>PM_2.5, PM₁₀, and SO₂ was significantly associated with elevated number of schizophrenia hospitalization. We observed the largest single-day effects of PM_2.5 at lag 17 day, PM₁₀ at lag 17 day, and SO₂ at lag 28 day, with the corresponding RRs being 1.01611 (95% CI:1.00652-1.02579), 1.01648 (95% CI:1.00603-1.02704), and 1.02001 (95% CI: 1.00001-1.04041), respectively. Stratification analysis revealed that patients who were < 45 years old and female were more vulnerable to hospitalization due to exposure to PM_2.5 and PM₁₀. The effects of PM_2.5 and PM₁₀ were more noticeable during the cooler seasons than during the warmer one.</p><p><strong>Conclusions: </strong>This study reveals that being exposed to PM_2.5, PM₁₀, and SO₂ may increase the chance of schizophrenia hospitalization.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and facilitators to accessing sexual and reproductive health services for people with severe mental illness: a systematic review.","authors":"Matilda Brown, Emma Tassie, Sophie Carlisle, Elana Covshoff, Amy Ronaldson, Julie Williams, Shubulade Smith, Kylee Trevillion, Elizabeth Hughes, Margaret Heslin","doi":"10.1007/s00127-025-02844-0","DOIUrl":"https://doi.org/10.1007/s00127-025-02844-0","url":null,"abstract":"<p><strong>Purpose: </strong>Despite increased prevalence of sexual and reproductive health problems among people with severe mental illness (SMI), uptake of sexual and reproductive healthcare in this group is poor. The reasons for this are unclear. Therefore, this review aimed to identify the barriers and facilitators to accessing sexual and reproductive health services from a service user perspective.</p><p><strong>Methods: </strong>Three electronic databases were searched using key words for \"sexual health\" and \"SMI\". Data were screened and extracted by two independent reviewers. The Joanna Briggs Institute Critical Appraisal Tools were used to assess quality of included studies.</p><p><strong>Results: </strong>Five studies were included and underwent a narrative synthesis. They were on access to HIV care (n2), access to family planning methods (n2) and access to general sexual healthcare (n1). Barriers relating to HIV care included cost; barriers relating to family planning included lack of awareness and not considering the issue; barriers to general sexual healthcare included psychotic symptoms, mental health prioritisation, stigma, lack of sexual health focus in mental health programs, difficulty initiating conversations, knowledge, culture/religion/ethnicity, and finances.</p><p><strong>Conclusions: </strong>Studies which examined access to HIV and family planning services did so in a way that limited participant responses. While only one study examined barriers and facilitators to accessing generic sexual health services, it did so robustly, although it focussed solely on young women and provided limited data on facilitators. Future work should focus on examining barriers, and facilitators, to accessing sexual healthcare in all people with SMI to better identify and address these challenges. PROSPERO ID CRD42023414740.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Special needs of refugees with substance use disorders from conflict-affected countries: a comparison with German-born individuals.","authors":"Mayte López-Atanes, Moritz Rosenkranz, Leire Erkoreka, Maria Recio-Barbero, Melav Bari, Philipp Hiller, Simone Penka, Jutta Lindert, Marcus Martens, Ingo Schäfer","doi":"10.1007/s00127-025-02842-2","DOIUrl":"https://doi.org/10.1007/s00127-025-02842-2","url":null,"abstract":"<p><strong>Background: </strong>Refugees seem to be at enhanced risk for substance use disorders. At the same time, they have less access to services and their health needs remain poorly understood. This study aims to evaluate the specific needs of refugees as compared to German-born individuals seeking help for substance use disorders.</p><p><strong>Methods: </strong>We conducted an observational case-control study using all treatment episodes in outpatient addiction facilities in three German federal states during the year 2020. A total of 719 refugee clients were matched to 713 German-born individuals using propensity score matching. We compared potential needs related to features of substance use as well as different psychosocial areas.</p><p><strong>Results: </strong>The final sample of refugees was composed of n = 384 (26.8%) cases from Afghanistan, n = 214 (14.9%) from Syria and n = 121 (8.4%) from Iraq. Clients consulted mostly due to cannabis use (44.8%) or opioid use (20.1%). Intravenous use of drugs and needle sharing was significantly lower in refugees (p < 0.05). A higher proportion of refugees than Germans lived in provisional housing, were unemployed or in charge of minor children (p < 0.05). Mental and physical comorbidities were significantly higher in refugees (p < 0.05). They were also more likely to have been victims of violence and less likely to present violent behaviors.</p><p><strong>Conclusion: </strong>Refugees with substance use disorders differ regarding a spectrum of psychosocial issues from German-born individuals. This highlights the need to link addiction treatment with other parts of the health care and psychosocial support systems to provide adequate care for this group.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal risk factors for young adults to be not engaged in employment, education or training (NEET) and its mediators: longitudinal analysis of the QLSCD cohort study.","authors":"Rebecca Falutz, Massimiliano Orri, Michel Boivin, Richard E Tremblay, Sylvana M Côté, Marilyn N Ahun","doi":"10.1007/s00127-025-02841-3","DOIUrl":"https://doi.org/10.1007/s00127-025-02841-3","url":null,"abstract":"<p><strong>Purpose: </strong>In 2019, 31% and 14% of young women and men worldwide - respectively - reported being not engaged in employment, education, or training (NEET), an important indicator of long-term socioeconomic vulnerability. This study examined the developmental pathways leading to NEET status in young adulthood by investigating the association between perinatal adversities and NEET status and the mediating role of adolescent externalizing behaviours.</p><p><strong>Methods: </strong>Data were from the Québec Longitudinal Study of Child Development (QLSCD, n = 974). Latent class analysis identified four profiles of exposures to 30 perinatal adversities: Low adversity, the reference group; Fetal growth adversity, which includes participants experiencing adversity related to growth problems in utero and after birth; Delivery complications, which includes participants - or their mothers - who experience complications during birth; and Familial adversity, which includes participants who experienced adversity related to their family life. The associations between the perinatal profiles, NEET status - which was self-reported at age 21 years - and the putative mediating role of externalizing behavioural problems (self-reported at ages 15 and 17) were investigated using structural equation modeling.</p><p><strong>Results: </strong>The risk of becoming NEET at age 21 was higher for children who experienced familial (OR = 3.19 [95% CI: 2.31-4.40], p < 0.001) and fetal growth (2.03 [1.11-3.71], p = 0.022) adversity. Externalizing behaviour problems mediated the association between familial adversity and NEET status (1.17 [1.05-1.30], p = 0.004).</p><p><strong>Conclusion: </strong>Interventions targeting perinatal risk factors and adolescent mental health can contribute to efforts to prevent NEET status in young adulthood.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moderate and severe depression increase the incidence of cholelithiasis: Results from Mendelian randomization study and the NHANES 2017-March 2020.","authors":"Mingxiu Ma, Kailing Xie, Tianqiang Jin, Feng Xu","doi":"10.1007/s00127-025-02843-1","DOIUrl":"https://doi.org/10.1007/s00127-025-02843-1","url":null,"abstract":"<p><strong>Background: </strong>Depression may be a contributing factor to cholelithiasis. However, the exact correlation between cholelithiasis and depression severity remains unclear.</p><p><strong>Methods: </strong>First, a two-sample Mendelian randomization (MR) analysis was performed to validate previous research findings, utilizing separate datasets for major depressive disorder (MDD) and cholelithiasis. The MDD dataset (135,458 cases, 344,901 controls) came from a published GWAS, and cholelithiasis data (19,023 cases, 195,144 controls) were sourced from FinnGen. The primary analytical approach for the MR study was the inverse variance weighting (IVW) method. Second, an observational study based on the National Health and Nutrition Examination Survey (NHANES) was conducted to explore the relationship between the severity of depression and cholelithiasis. 7071 participants were included in the observational study in total. Depression severity (no, mild, moderate, severe) was measured by Patient Health Questionnaire-9 (PHQ-9). Weighted multivariable-adjusted logistic regression was employed to assess the association between depression severity and cholelithiasis.</p><p><strong>Results: </strong>In the MR study, the IVW analysis revealed that MDD may increase the risk of cholelithiasis (OR 1.25, 95% CI 1.07-1.45, P = 0.004). The observational study showed that moderate (OR 1.06, 95% CI 1.00-1.11, p = 0.037) and severe (OR 1.07, 95% CI 1.00-1.15, p = 0.044) depression rises the incidence of cholelithiasis. However, no significant association was found between mild depression and cholelithiasis (p = 0.275).</p><p><strong>Conclusions: </strong>Moderate and severe depression might rise the incidence of cholelithiasis, while mild depression may not. Further validation through prospective studies is necessary.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caregiver mental, behavioral, and social health during the COVID-19 pandemic in South Africa: results from the Asenze cohort study.","authors":"Lina Y Demis, Chris Desmond, Rachel S Gruver, Furzana Timol, Leslie L Davidson, Jeremy C Kane","doi":"10.1007/s00127-024-02811-1","DOIUrl":"https://doi.org/10.1007/s00127-024-02811-1","url":null,"abstract":"<p><strong>Purpose: </strong>The COVID-19 pandemic and subsequent lockdowns had significant impacts on the well-being of populations globally, however, most COVID-19 mental health research has been done in high-income countries. This study evaluates the impact of COVID-19 and lockdowns on the mental well-being of sequential groups of caregivers of adolescents in South Africa. We hypothesized that caregivers experienced worse mental, emotional and social health outcomes during the pandemic, compared to before its onset.</p><p><strong>Methods: </strong>Longitudinal data from Wave 3 of the Asenze Cohort, conducted between 2019 and 2021, was used to estimate multivariable regressions to assess the association between pandemic lockdowns and caregiver social support networks, mental and physical health related quality of life, parenting stress, hazardous alcohol use, psychiatric disorder, and intimate partner violence.</p><p><strong>Results: </strong>Results show that after the onset of the pandemic, caregivers experienced diminished social support networks, worse physical health related quality of life, and improvement in mental health related quality of life compared to before the pandemic. We observed no association between pandemic lockdowns with parenting stress, hazardous alcohol use, the presence of any psychiatric disorder, or experience of intimate partner violence.</p><p><strong>Conclusion: </strong>This study shows the impact of COVID-19 and mandated lockdowns on caregiver social support, mental and physical health related quality of life among caregivers of adolescents in South Africa. Given the results, more research is needed to discern modifiable risk factors that can be intervened on to improve social support and physical health related quality of life, and to preserve mental health related quality of life.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}