Social Psychiatry and Psychiatric Epidemiology最新文献

{"title":"Braving the dark: mental health challenges and academic performance of Ukrainian university students during the war.","authors":"Irina Pinchuk, Inna Feldman, Violetta Seleznova, Volodymyr Virchenko","doi":"10.1007/s00127-025-02867-7","DOIUrl":"https://doi.org/10.1007/s00127-025-02867-7","url":null,"abstract":"<p><strong>Purpose: </strong>The paper aims to investigate the association of mental health problems with academic performance of university students using data from a cross-sectional survey of Ukrainian university students during the war. The prevalence of mental health problems among students with their subsequent division into different severity groups is investigated.</p><p><strong>Methods: </strong>The study combines a cross-sectional survey method to collect data and a regression analysis technique to identify mental health problems that negatively associated with students' academic performance during the war. The survey questionnaire includes a demographic section, mental health screening tools, as well as Work Productivity and Activity Impairment: Special Health Problems (WPAI: SHP) section, adapted for the purpose of the study. The data sample includes responses from 1398 university students from different regions of Ukraine.</p><p><strong>Results: </strong>According to survey data 85.8% of all respondents had depression symptoms, 66.1%- anxiety symptoms, 56.9%-sleep problems, and 48.1%- PTSD symptoms. Results of regression modeling confirms the devastating effect of mental health problems on academic performance of university students during the war, in particular, a severe depression symptoms, anxiety symptoms and sleep problems are associated with 17.4%, 12.2% and 11.0% decrease in academic performance of university students, respectively.</p><p><strong>Conclusion: </strong>The prevalence of mental health problems and related academic performance impairment among students during wartime become a challenge for the successful recovery of Ukrainian society and therefore require a quick response at both the institutional and public policy levels.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the COVID-19 pandemic on antidepressant consumption in the Central region of Portugal: interrupted time series.","authors":"Luciana G Negrão, Catarina Coelho, M Margarida Castel-Branco, Isabel V Figueiredo, Fernando Fernandez-Llimos","doi":"10.1007/s00127-024-02731-0","DOIUrl":"10.1007/s00127-024-02731-0","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of the pandemic on the consumption of antidepressive agents in Central Portugal.</p><p><strong>Methods: </strong>To estimate the causal effect of the pandemic an interrupted time series analysis was conducted. Data of antidepressant drugs monthly dispensed in community pharmacies between Jan-2010 and Dec-2021 were provided by the regional Health Administration. Anti-Parkinson dopaminergic agents and statins, theoretically not influenced by COVID-19 pandemics, were used as comparator series. The number of packages was converted into defined daily doses and presented as defined daily doses/1000 inhabitants/day. A Bayesian structural time-series model with CausalImpact on R/RStudio was used to predict the counterfactual. Analyses with different geographical granularity (9 sub-regions and 78 municipalities) were performed.</p><p><strong>Results: </strong>When compared to counterfactual, regional consumption non-significantly increased after the pandemic declaration, with a relative effect of + 1.30% [95%CI -1.6%:4.2%]. When increasing the granularity, differences appeared between sub-region with significant increases in Baixo Mondego + 6.5% [1.4%:11.0%], Guarda + 4.4% [1.1%:7.7%] or Cova da Beira + 4.1% [0.17%:8.3%], but non-significant variation in the remaining 6 sub-regions. Differences are more obvious at municipality level, ranging from increases of + 37.00% [32.00%:42.00%] to decreases of -11.00% [-17.00%:-4.20%]. Relative impact positively correlated with percentage of elderly in the municipality (r = 0.301; p = 0.007), and negatively with population density (r=-0.243; p = 0.032). No other predicting variables were found.</p><p><strong>Conclusion: </strong>Antidepressant consumption suffered very slight variations at regional level after the COVID-19 pandemic declaration. Analysis with higher granularity allowed identifying municipalities with higher impact (increase or decrease). The absence of clear association patterns suggests other causal hypotheses of the differences.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"621-629"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-COVID social engagement and depression among Chinese older adults: exploring rural/urban and gender differences.","authors":"Keqing Zhang, Wei Zhang","doi":"10.1007/s00127-024-02752-9","DOIUrl":"10.1007/s00127-024-02752-9","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates the impact of post-COVID social engagement on depression levels among Chinese older adults, with a focus on rural/urban and gender differences.</p><p><strong>Methods: </strong>Using the year 2018 and year 2020 data from the China Health and Retirement Longitudinal Study (CHARLS), this study analyzed pre- and post-COVID depression levels and social engagement indicators, including going-out, activities and networking among Chinese older adults (N = 8,793).</p><p><strong>Results: </strong>Results showed a significant increase in depression levels across all demographic groups post-COVID, with rural females exhibiting the highest levels of depression. Reduced social engagement was associated with increased depression, particularly among rural males and females. Subgroup analyses highlighted nuanced patterns: rural males suffered from decreased intense activities and online contacts, while urban males experienced heightened depression with reduced visiting and light activities. Rural females reported increased depression with decreased moderate activities and dancing outdoors but decreased levels with reduced online contacts. Conversely, urban females experience decreased depression with reduced social engagements, suggesting areevaluation of priorities amidst pandemic challenges.</p><p><strong>Conclusion: </strong>This study has underscored the importance of considering individual, cultural, and contextual factors in understanding mental health outcomes among Chinese older adults. Findings inform targeted interventions aimed at promoting psychological well-being and resilience among Chinese older adults in the post-COVID era, including community-based programs and mental health screenings, to foster social connection and emotional support.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"645-656"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical course and demographic insights into suicide by self-poisoning: patterns of substance use and socio-economic factors.","authors":"Stefanie Geith, Maja Lumpe, Johannes Schurr, Sabrina Schmoll, Christian Rabe, Armin Ott, Raphael Stich, Michael Rentrop, Florian Eyer, Tobias Zellner","doi":"10.1007/s00127-024-02750-x","DOIUrl":"10.1007/s00127-024-02750-x","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze whether sociodemographic characteristics influence the substance choice and preclinical and clinical course of suicidal poisoning.</p><p><strong>Methods: </strong>This was a retrospective single-center study in patients hospitalized due to suicidal poisoning and who received at least one psychiatric exploration during their inpatient stay. Patients' sociodemographic, anamnestic, preclinical, and clinical parameters were analyzed with respect to sex and age.</p><p><strong>Results: </strong>1090 patients were included, 727 (67%) were females, median age was 39 years (min-max: 13-91) with 603 (55%) aged 18-44 years. 595 patients (54.8%) ingested a single substance for self-poisoning, 609 (59.5%) used their own long-term medication. Comparing to males, females preferred antidepressants (n = 223, 30.7%, vs n = 85, 23.4%; p = 0.013) and benzodiazepines (n = 202, 27.8%, vs n = 65, 17.9%; p < 0.001); males more often used cardiovascular drugs (n = 33, 9.1%, vs n = 34, 4.7%; p = 0.005) and carbon monoxide (n = 18, 5.0%, vs n = 2, 0.3%; p < 0.001). Use of Z-drugs (n = 1, 1.7%, to n = 37, 33.3%; p < 0.001) and benzodiazepines (n = 4, 6.9%, to n = 33, 29.7%; p = 0.003) increased with age (< 18 to > 64 years), while use of non-opioid analgesics (n = 23, 39.7%, to n = 20, 18.0%; p < 0.001) decreased. Average dose of substance in patients > 64 years was 12.9 ± 18.4 times higher than recommended maximum daily dose (compared to 8.7 ± 15.2 higher in those aged < 18 years; p < 0.001). Males more often required intensive care (n = 150, 41.3%, vs n = 205 females, 28.2%; p < 0.001).</p><p><strong>Conclusion: </strong>These results underline the complexity of (para-)suicidal poisonings and identify potential measures for their prevention, such as restricting access and better oversight over the use of certain substances.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"705-718"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and anxiety in the context of the COVID-19 pandemic: A 6-waves longitudinal study in the Argentine population.","authors":"Hernán López-Morales, Rosario Gelpi Trudo, Matías Jonás García, Macarena Verónica Del-Valle, Matías Yerro, Fernando Martín Poó, Ornella Bruna, Lorena Canet-Juric, Sebastián Urquijo","doi":"10.1007/s00127-024-02746-7","DOIUrl":"10.1007/s00127-024-02746-7","url":null,"abstract":"<p><strong>Purpose: </strong>The pandemic has caused stress due to isolation, loss of loved ones, work and learning changes, financial instability, fear of infection, and uncertainty. It has negatively impacted mental health, particularly increasing anxiety, and depression symptoms. This study analyzed anxiety and depression symptoms over the first 25 months of the COVID-19 pandemic, considering age group, socioeconomic status, and gender.</p><p><strong>Methods: </strong>A longitudinal study with 6 repeated measures was conducted, involving 988 adult participants from Argentina. Adapted versions of the BDI-II and STAI were administered through online questionnaires at 2, 14, 50, 130, 390, and 750 days since the start of the lockdown.</p><p><strong>Results: </strong>The results showed a sustained increase in anxiety and depression symptoms up to 390 days, followed by a decrease in anxiety below initial levels at 750 days. Depressive symptoms significantly decreased after 750 days but remained higher than initial levels.</p><p><strong>Conclusion: </strong>Women consistently scored higher than men, lower socioeconomic status individuals reported more symptoms, and younger individuals had higher anxiety and depression, which decreased with age. Surprisingly, older individuals displayed better mental health indicators compared to the rest of the population.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"631-644"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of suicidal behaviors with body weight and body weight perception in Chinese adolescents: 2007-2022.","authors":"Yi Lin, Jin-Ying Huang, Richard Rankin, Wang-Wei Lou, Xiao-Yong Li, Si-Jia Wang, Feng Tong, Qing-Hai Gong","doi":"10.1007/s00127-024-02794-z","DOIUrl":"10.1007/s00127-024-02794-z","url":null,"abstract":"<p><strong>Purpose: </strong>To estimate the time trend in the prevalence of suicidal behaviors including ideation and attempts in Chinese adolescents; to examine the association between suicidal behaviors and overweight (OW)/obesity (OB) and self-perceived weight status.</p><p><strong>Methods: </strong>Data from Youth Risk Behavior Surveys conducted in Ningbo in 2007, 2012, 2017 and 2022 were used for the study. A multistage sampling procedure was used to select respondents aged 12 to 19 years who participated in each survey. Repeated cross-sectional data of anthropometry, weight perception and suicidal behaviors were collected through self-administered questionnaires. A generalized linear model was used to assess associations of ideation and attempts, and weight status and self-perceived weight status.</p><p><strong>Results: </strong>The sample sizes for each survey wave were 937, 889, 1528 and 2655. The prevalence of ideation increased from 11.95% in 2007 to 18.15% in 2022, while the prevalence of attempts remained stable (4.48%-4.26%). An increasing trend in ideation and attempts was found in adolescents who were OW/obese and self-perceived OW/OB from 2007 to 2022. Self-perceived OW/OB adolescents had a significant increase in ideation. Girls had higher likelihood of ideation and attempts for both weight status and self- perceived weight status. While, adolescents aged 12.0-15.9 years had higher odds of ideation than those aged 16.0-19.9 years.</p><p><strong>Conclusion: </strong>Adolescents' self-weight perception, rather than actual weight status, is a critical risk factor of increased likelihood of ideation and attempts in Chinese adolescents. Our findings can support to promote self-esteem growth in school-based health education programmes for prevention of suicidality and psychological health problems.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"737-749"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal association of exposure to work-related stress with major depressive disorder and the role of occupational burnout in this association in the general population.","authors":"Yara Shoman, Setareh Ranjbar, Marie-Pierre F Strippoli, Roland von Känel, Martin Preisig, Irina Guseva Canu","doi":"10.1007/s00127-024-02735-w","DOIUrl":"10.1007/s00127-024-02735-w","url":null,"abstract":"<p><strong>Purpose: </strong>To prospectively assess (1) the associations of Effort-Reward Imbalance (ERI), its individual components, and over-commitment with (a) the onset of a Major Depressive Episode (MDE) during a 3.6-year follow-up in a population-based cohort in participants with no current Major Depressive Disorder (MDD) in the beginning of the follow-up (n = 959), (b) incidence of MDD in the subsample of participants exempt from lifetime MDD (n = 490), and (c) the onset of a new MDE (i.e. recurrence) in the subsample of participants with remitted but no current MDD (n = 485), and (2) potential effect modification of burnout on these associations.</p><p><strong>Methods: </strong>DSM-IV Axis-I disorders were elicited using the semi-structured Diagnostic Instrument for Genetic Studies at each investigation. The ERI Questionnaire was used to measure ERI and overcommitment. Burnout was measured with the Maslach Burnout Inventory General Survey. Serially adjusted logistic regression models were used. The effect of burnout dimensions on these associations was assessed by testing interactions between the ERI and burnout dimensions.</p><p><strong>Results: </strong>(1) ERI was prospectively associated with the onset of MDE, even after adjustment for burnout [OR (95CI) = 1.22 (1.003-1.49)]. (2) The association between ERI and MDD incidence became non-significant after adjusting for burnout. (3) ERI was not associated with recurrence of pre-existing MDD. (4) burnout did not interact with ERI.</p><p><strong>Conclusions: </strong>Our results support a longitudinal association between ERI and the risk of onset of MDE in the community. Burnout did not modify this effect, but it may partially account for the association between ERI and MDD incidence.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"593-606"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A \"Self-Milieux\" perspective on help-seeking: examining the impact of a person's sociocultural background on help-seeking in people with untreated depressive symptoms.","authors":"Thomas McLaren, Lina-Jolien Peter, Samuel Tomczyk, Holger Muehlan, Georg Schomerus, Silke Schmidt","doi":"10.1007/s00127-024-02720-3","DOIUrl":"10.1007/s00127-024-02720-3","url":null,"abstract":"<p><strong>Background: </strong>Mental illness is a global concern and the leading cause of years lived with disability. Research on help-seeking behaviour has focused on individual factors, but there is still much unexplained variance. Suggesting complex interactions between determinants of human behaviour a new framework called Self-Milieux is proposed to represent a person's sociocultural background. The article introduces a statistical approach to determine Self-Milieux and exemplarily examines its predictive validity for health-related research.</p><p><strong>Methods: </strong>Self-Milieux are determined through a two-stage clustering method based on the determinants socioeconomic status and self-construal profile. Descriptive analyses are used to compare Self-Milieux characteristics. Hierarchical binary logistic regression models test the association between Self-Milieux and help-seeking behaviour, while controlling for socioeconomic status as an established predictor.</p><p><strong>Results: </strong>The sample size was N = 1535 (M_age = 43.17 and 64.89% female participants). Average depression severity was M = 12.22, indicating mild to moderate symptoms. Six Self-Milieux were determined and named. Participants from privileged (aOR = 0.38) and self-sufficient (aOR = 0.37) milieux were less likely to seek help from a general practitioner than those from the entitled milieu. Participants from privileged (aOR = 0.30), collaborators (aOR = 0.50), disadvantaged (aOR = 0.33), and self-sufficient (aOR = 0.21) milieux were less likely to seek help from family members than those from the entitled and family-bound milieux.</p><p><strong>Discussion: </strong>The study's strengths and limitations, as well as the cluster methodology, are discussed. The comparative results for the six Self-Milieux are interpreted based on current research. For example, participants from some milieux follow a help-seeking process proposed in previous research, while participants from other milieux seem to show a different process, one that ends in informal help-seeking.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"579-592"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141890654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between gun violence exposure and suicide mortality rates in US counties.","authors":"Konstantinos Christopoulos","doi":"10.1007/s00127-024-02771-6","DOIUrl":"10.1007/s00127-024-02771-6","url":null,"abstract":"<p><strong>Purpose: </strong>Gun violence traumatizes communities and places a heavy burden on the mental health of those exposed. This ecological study examines the association between gun violence exposure and suicide mortality rates in US counties for the period 1999-2020 at various urbanicity levels.</p><p><strong>Methods: </strong>A Bayesian hierarchical Gamma-Poisson model with state random effects was employed to model the age-adjusted suicide mortality rates which adjusted for sex ratio, urbanicity, social vulnerability, gun ownership, culture of honor, and exposure spillovers from neighbouring counties.</p><p><strong>Results: </strong>Results indicate a small significant positive association between gun violence and suicide mortality rates. Urbanicity levels do not appear to modify this association, although the association may be slightly smaller for large urban metros.</p><p><strong>Conclusions: </strong>Gun violence exposure may be positively associated with suicide mortality in US counties.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"719-725"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social connection interventions and depression in young adults: a systematic review and meta-analysis.","authors":"Clotilde Vazquez Alvarez, Luwaiza Mirza, Jayati Das-Munshi, Tassia Kate Oswald","doi":"10.1007/s00127-024-02722-1","DOIUrl":"10.1007/s00127-024-02722-1","url":null,"abstract":"<p><strong>Purpose: </strong>Early adulthood is a period which may increase vulnerability to loneliness and mental health difficulties among young adults. Social networks play an important role in buffering against adverse mental health, but there is a lack of evidence around whether social connection interventions could play a role in preventing mental health difficulties for young adults.</p><p><strong>Methods: </strong>A systematic review and meta-analysis was conducted (PROSPERO ID: CRD42023395595). PubMed, PsycInfo, and Scopus were searched (01 January 2000-01 January 2023). Studies were eligible if they (i) were quantitative, (ii) included young adults (18-24 years) from the general population, (iii) tested a social intervention which aimed to increase the quantity or quality of social connections or reduce loneliness, (iv) had a comparison group, and (v) measured depression and loneliness/social connection as outcomes. Following study screening and selection, the data extraction and risk of bias assessments were independently conducted in duplicate. The Cochrane RoB-2 tool and ROBINS-I tool were used to assess risk of bias. Results were narratively synthesised and random effects meta-analysis with standardised mean differences was conducted.</p><p><strong>Results: </strong>Six studies were included; four in-person interventions with higher education students, one online intervention with higher education students, and one intervention for youth involved in street life. The studies were mostly rated as having some or moderate concerns with risk of bias. The interventions were associated with an overall mean reduction in depression for young adults (SMD = -0.19; 95% CI, -0.33 to -0.05; p = 0.008; 4 studies, excluding studies with serious risk of bias). All interventions had beneficial effects on a range of diverse social connection outcomes, but there was no overall statistically significant mean reduction in loneliness for young adults in pooled analyses (SMD = -0.10; 95% CI, -0.24 to 0.05; p = 0.188; 3 studies).</p><p><strong>Conclusion: </strong>Social connection interventions show some promise in improving depression and social connection outcomes in young adults but more high-quality research, across diverse settings, is needed in this area.</p>","PeriodicalId":49510,"journal":{"name":"Social Psychiatry and Psychiatric Epidemiology","volume":" ","pages":"549-562"},"PeriodicalIF":3.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}