Taiwanese Journal of Obstetrics & Gynecology最新文献

{"title":"The effect of aromatherapy with Citrus Aurantium essential oil on depression, stress and anxiety in pregnant women; a randomized controlled clinical trial","authors":"Maryam Moradi ,&nbsp;Azin Niazi ,&nbsp;Fereshteh Mohammadi Payandar ,&nbsp;Jamshid Jamali ,&nbsp;Noushin Arefadib","doi":"10.1016/j.tjog.2024.10.020","DOIUrl":"10.1016/j.tjog.2024.10.020","url":null,"abstract":"<div><h3>Objective</h3><div>Many women experience high stress, anxiety or depression during pregnancy. The aim of this study was to determine the effect of aromatherapy with Citrus Aurantium essential oil on depression, stress and anxiety in pregnant women.</div></div><div><h3>Materials and methods</h3><div>This randomized clinical trial included 68 pregnant women who were randomly assigned to either the intervention group where they received five drops of Citrus Aurantium essential oil or the control group where they received odorless sweet almond oil, both twice a day for one month in the form of facemasks which they inhaled through normal breathing for 20 min. The Depression, Anxiety, and Stress Scale–21 Items (DASS-21) were administered pre-and post-intervention. Data analysis was performed within SPSS software (version 24). P-value&lt;0.05 was considered statistically significant.</div></div><div><h3>Results</h3><div>The mean gestational age was 29.30 ± 2.14 weeks in the control group and 28.43 ± 1.95 weeks in the intervention group (p = 0.089). In bi-variable analysis, the intervention significantly improved all depression, anxiety and stress scores. Depression scores significantly decreased in the intervention group compared to the placebo group (−4.80 ± 6.22 vs. 1.03 ± 5.90) (p &lt; 0.001). Similarly, anxiety scores were reduced after the intervention (−3.37 ± 3.52 vs. 0.79 ± 4.39) (p &lt; 0.001). Although stress scores improved more in the intervention group compared to placebo group (−3.77 ± 4.94 vs. 1.39 ± 4.99), the difference was not statistically significant (p = 0.166). However, a more sophisticated analysis revealed that the intervention had a significant effect on depression (p = 0.001) and anxiety (p &lt; 0.001) but not on stress (p = 0.166).</div></div><div><h3>Conclusion</h3><div>Aromatherapy with Citrus Aurantium essential oil is effective and safe in reducing depression and anxiety in pregnant women. However, further research is needed to clarify its impact on stress reduction.</div></div><div><h3>Trial Registration Number</h3><div>IRCT20200512047414N1.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 512-518"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autogenic uterus transplantation in goats: Animal model experience in Taiwan","authors":"Cherry Yin-Yi Chang ,&nbsp;Chien-Chu Huang ,&nbsp;Shih-Te Chuang ,&nbsp;Jui-Chun Hsieh ,&nbsp;Ping-Chun Li ,&nbsp;Yu-Wen Sung ,&nbsp;Kin-Shing Poon ,&nbsp;Hsiu-Yu Lai ,&nbsp;Wu-Chou Lin","doi":"10.1016/j.tjog.2025.04.002","DOIUrl":"10.1016/j.tjog.2025.04.002","url":null,"abstract":"<div><h3>Objective</h3><div>Uterus transplantation (UTx) is a solution for women with uterine infertility. In this study, we aimed to explore surgical methods for autogenic UTx in a goat model and assess the function of the uterus and the surgical outcome.</div></div><div><h3>Materials and methods</h3><div>Female goats (n = 4) underwent autologous transplantation of the uterus via laparotomy. The pelvic tissue was carefully dissected and exposed. The uterine arteries were dissected to the entire internal iliac artery, and the ovarian veins were also dissected to the point where they crossed over the ureter. Back-table preparation was performed when the graft was removed. After the end-to-side anastomosis of the blood vessels was completed, vaginal anastomosis was performed. The surgery time, ischemia time, and surgical outcomes were recorded. After surgery, the viability of the uterus was examined via hysteroscopy, and an endometrial biopsy was performed.</div></div><div><h3>Results</h3><div>Overall, the survival rate of the animals was 75 % (one goat died because of an allergic reaction to the anesthetic medication one day after the operation). Among the three surviving goats, two resumed ovarian cyclicity. Adhesions in the cavity were observed in one goat.</div></div><div><h3>Conclusion</h3><div>The goat UTx model is a good model for performing this procedure. Our results revealed that uterine function resumed in the majority of the animals, although pregnancy could not be confirmed.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 519-523"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Internal iliac artery blockade","authors":"I-Gung Li,&nbsp;Chia-Hao Liu,&nbsp;Peng-Hui Wang","doi":"10.1016/j.tjog.2024.03.032","DOIUrl":"10.1016/j.tjog.2024.03.032","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 402-403"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-level mosaic trisomy 7 at amniocentesis in a pregnancy associated with postnatal progressive decrease of the trisomy 7 cell line and a favorable fetal outcome despite postnatal manifestation of patterned hypopigmentation of skin","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.03.010","DOIUrl":"10.1016/j.tjog.2025.03.010","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 564-566"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis and counseling of Emanuel syndrome: Two case reports","authors":"Chi-Yuan Chiang ,&nbsp;Zih-Ning Liu ,&nbsp;Shu-O Chiu ,&nbsp;Yu-Ting Lin ,&nbsp;Hsiu-Huei Peng ,&nbsp;Shuenn-Dyh Chang","doi":"10.1016/j.tjog.2024.10.022","DOIUrl":"10.1016/j.tjog.2024.10.022","url":null,"abstract":"<div><h3>Objective</h3><div>Emanuel syndrome is a rare inherited chromosomal disorder characterized by the presence of a derivative chromosome 22 resulting from a translocation between chromosomes 11 and 22. Since the number of reported cases in Asian is still small, we mean to present 2 more cases diagnosed prenatally and review similar case reports to better understand the syndrome when abnormal findings were found prenatally.</div></div><div><h3>Case report</h3><div>Two cases of Emanual syndrome were found where one draws attention due to abnormal serum marker and thickened nuchal translucency, and the other was found when prenatal ultrasonography detected multiple anomalies. Genetic amniocentesis revealed 47 chromosomes gaining an additional marker chromosome arising from malsegregation in a balanced translocation heterozygote with 46, XX, t(11;22) (q23.3;q11.2).</div></div><div><h3>Conclusion</h3><div>While different anomalies were found, both of our cases along with others presented 3:1 segregation with tertiary trisomy resulting in Emanual syndrome. Chromosome of the quadrivalent is small in content (“lop-sided” quadrivalent) at meiosis I, which tends to separate in a 3:1 segregation fashion.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 535-539"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The associations of fetomaternal hemorrhage with fetal growth restriction and umbilical cord abnormalities: A nationwide observational study","authors":"Yoshimitsu Wada,&nbsp;Hironori Takahashi,&nbsp;Manabu Ogoyama,&nbsp;Kenji Horie,&nbsp;Hirotada Suzuki,&nbsp;Rie Usui,&nbsp;Seung Chik Jwa,&nbsp;Akihide Ohkuchi,&nbsp;Hiroyuki Fujiwara","doi":"10.1016/j.tjog.2024.11.009","DOIUrl":"10.1016/j.tjog.2024.11.009","url":null,"abstract":"<div><h3>Objective</h3><div>Fetomaternal hemorrhage (FMH) causes severe neonatal outcomes; however, due to its rarity, risk factors for FMH occurrence and prognostic factors for its outcomes remain unclear. Thus, we aimed to investigate factors for FMH occurrence and related outcomes.</div></div><div><h3>Materials and methods</h3><div>We included singleton pregnant women from the Japanese nationwide perinatal registry database between 2013 and 2019. To investigate the association between characteristics and FMH occurrence, we conducted multivariable logistic regression model analyses. In addition, we employed multivariable logistic regression models to evaluate prognostic factors of stillbirth or neonatal death among FMH. We used multiple imputation to handle missing data in all analyses.</div></div><div><h3>Results</h3><div>Of 1,500,309 women, FMH occurred in 141 (1/10,640). A sinusoidal pattern was detected in only 20.6 % of women with FMH. The proportion of women who had fetal growth restriction (FGR) was 10/141 (7.1 %) in those with FMH and 54,989/1,500,168 (3.7 %) in those without FMH. A single umbilical artery was found in 2/141 (1.4 %) and 3845/1,500,168 (0.3 %) women with and without FMH, respectively. FGR and a single umbilical artery were significantly associated with FMH occurrence (adjusted odds ratio [OR], 2.01; 95 % confidence interval [CI], 1.06–3.83; <em>p</em> = 0.033) (adjusted OR, 5.51; 95 % CI, 1.36–22.27; <em>p</em> = 0.017), respectively. In addition, abnormal umbilical cord insertion was significantly associated with stillbirth or neonatal death among FMH (adjusted OR, 19.95; 95 % CI, 2.33–170.63; <em>p</em> = 0.006).</div></div><div><h3>Conclusion</h3><div>The occurrence of FMH was significantly associated with FGR and a single umbilical artery. In addition, abnormal umbilical cord insertion was significantly associated with stillbirth or neonatal death among those with FMH. We need to be cautious regarding FMH occurrence in women with FGR or a single umbilical artery. In addition, perinatal outcomes in women with FMH, especially those with abnormal umbilical cord insertion, would be adverse.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 487-492"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis and management of desbuquois dysplasia type 1 due to CANT1 mutation: A case report","authors":"Miraç Özalp ,&nbsp;Murat İbrahim Toplu ,&nbsp;Biray Ertürk ,&nbsp;Aybekcan Batman ,&nbsp;Veli Mihmanlı","doi":"10.1016/j.tjog.2024.11.010","DOIUrl":"10.1016/j.tjog.2024.11.010","url":null,"abstract":"<div><h3>Objective</h3><div>To report a rare case of Desbuquois dysplasia Type 1 (DBQD1) diagnosed prenatally, caused by mutations in the CANT1 gene.</div></div><div><h3>Case report</h3><div>DBQD1 is an autosomal recessive skeletal dysplasia with severe disproportionate dwarfism, joint laxity, and multiple skeletal anomalies. A 26-year-old woman, gravida 3, para 1, abortus 1, was referred due to short femur (FL) and humerus (HL) lengths on ultrasound. The patient and her husband are consanguineous. Ultrasound at our clinic revealed a hypoplastic thorax, severe limb anomalies, brachydactyly, overlapping fingers, clubfoot, and rocker-bottom feet, along with ventricular septal defects (VSDs). Genetic testing identified a homozygous pathogenic variant in the CANT1 gene (c.902_906dup, p.Ser303AlafsTer21). Both parents were heterozygous carriers. Following genetic counseling, the family opted for pregnancy termination.</div></div><div><h3>Conclusion</h3><div>This case highlights the importance of comprehensive genetic testing and early, precise diagnosis for informed decision-making in managing rare skeletal dysplasias.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 531-534"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concerns regarding “Rejection and transfer”","authors":"Shigeki Matsubara,&nbsp;Daisuke Matsubara","doi":"10.1016/j.tjog.2025.02.004","DOIUrl":"10.1016/j.tjog.2025.02.004","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 586-587"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental detection of a balanced X;autosome translocation of 46,X,t(X;8)(q28;q24.22) in a 32-year-old, unmarried woman with irregular menstrual cycle","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.03.012","DOIUrl":"10.1016/j.tjog.2025.03.012","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 569-570"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometrial cancer: Part II. Multimodality treatment of uterine high-grade serous carcinoma (clinical course II)","authors":"Che-Wei Chang ,&nbsp;Szu-Ting Yang ,&nbsp;Wen-Hsun Chang ,&nbsp;Wen-Ling Lee ,&nbsp;Peng-Hui Wang","doi":"10.1016/j.tjog.2025.04.001","DOIUrl":"10.1016/j.tjog.2025.04.001","url":null,"abstract":"<div><div>The part II (clinical course I) of endometrial cancer (EC) describing the complex clinical course (initial treatment and therapy for the first recurrence at both local-regional and distant metastatic sites) of a 66-year-old woman with uterine high-grade serous carcinoma (HGSC, post-curettage diagnosis) after minimally invasive surgery (MIS) treatment-confirmed absence of residual tumor. In the clinical course I, we discussed the recent trend in using MIS for treating early-stage EC patients, regardless whether histologic types are classified, as well as the rationale of absent following postoperative adjuvant therapy due to no residual tumor of gross specimen after complete staging surgery. The patient had multiple recurrences at both loco-regional and distant sites after 22-month disease-free survival (DFS). After salvage therapy, including incomplete cytoreductive surgery for symptom control, chemotherapy, radiotherapy and final systemic therapy, the patient had a durable response period (10-month treatment plus 9 months of the 2nd progression-free survival [PFS]). The current report is the subsequent clinical course of this patient (clinical course II), which further managed this patient at the second recurrence based on multiple modality treatment to achieve the durable response and significantly improve the quality of life.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 425-433"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}