{"title":"Postmortem detection of trisomy 18 in a fetus with hydrops fetalis by conventional cytogenetic analysis of cultured umbilical cord cells","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.07.005","DOIUrl":"10.1016/j.tjog.2025.07.005","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 5","pages":"Pages 890-891"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145026495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-term follow-up of a 6-year-old boy with a prenatally detected de novo 16p13.11 microdeletion associated with no apparently phenotypic abnormality","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.07.007","DOIUrl":"10.1016/j.tjog.2025.07.007","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 5","pages":"Pages 895-897"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Best practices and learning need incorporate with artificial intelligent (AI) resources","authors":"Chyi-Long Lee","doi":"10.1016/j.tjog.2025.04.012","DOIUrl":"10.1016/j.tjog.2025.04.012","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 5","pages":"Pages 761-762"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Postmortem detection of trisomy 18 in a fetus with increased nuchal translucency and bilateral radial ray defects by conventional cytogenetic analysis of cultured placental cells","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.07.006","DOIUrl":"10.1016/j.tjog.2025.07.006","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 5","pages":"Pages 892-894"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145026496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chia-Ju Lin , Jung-Jung Chang , Chien-Wei Chen , Kuo-Wei Ho , Huei-Chieh Chuang , Yu-Che Ou , Ling-Yun Cheng , Chao-Yu Chen
{"title":"Severe endometriosis complicated by deep vein thrombosis and pulmonary embolism in the absence of hormone therapy: A case report and literature review","authors":"Chia-Ju Lin , Jung-Jung Chang , Chien-Wei Chen , Kuo-Wei Ho , Huei-Chieh Chuang , Yu-Che Ou , Ling-Yun Cheng , Chao-Yu Chen","doi":"10.1016/j.tjog.2025.01.013","DOIUrl":"10.1016/j.tjog.2025.01.013","url":null,"abstract":"<div><h3>Objective</h3><div>To report a rare case of severe endometriosis complicated by deep vein thrombosis (DVT) and pulmonary embolism (PE) without hormone exposure, and review similar cases in the literature.</div></div><div><h3>Case report</h3><div>A 44-year-old woman with severe endometriosis adenomyosis without hormone therapy history, presented with menorrhagia, dysmenorrhea, and an extremely high serum cancer antigen (CA)-125 level (1065.2 U/mL). Prior to scheduled surgery, she developed mild swelling over her left leg and was found to have extensive DVT over left common femoral to popliteal veins and bilateral multi-focal PE. After anticoagulation therapy and inferior vena cava filter placement, she underwent laparotomic total hysterectomy, bilateral salpingectomy, and ovarian tumor excision. Pathology confirmed endometriosis without malignancy. Postoperative follow-up revealed a normalized CA-125 level and resolution of thromboembolism.</div></div><div><h3>Conclusion</h3><div>This case emphasizes the importance of considering thrombotic complications in endometriosis patients with an extremely high CA-125 level, even without hormone exposure or vascular compression.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 5","pages":"Pages 878-881"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prenatal diagnosis of a familial heterozygous pathogenic variant in the PTPN11 gene (c.1510A>G, p.M504V) in a fetus with increased nuchal translucency and pleural effusion and a mother carrier with atypical Noonan syndrome","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.07.002","DOIUrl":"10.1016/j.tjog.2025.07.002","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 5","pages":"Pages 884-885"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pneumothorax during lenvatinib plus pembrolizumab for recurrent endometrial cancer: A case report","authors":"Masahiro Taguchi, Yoshifumi Takahashi, Miku Nakamura, Yuji Takei, Hiroyuki Fujiwara","doi":"10.1016/j.tjog.2025.03.016","DOIUrl":"10.1016/j.tjog.2025.03.016","url":null,"abstract":"<div><h3>Objective</h3><div>Pneumothorax is a rare adverse event in cancer treatment. Lenvatinib, a multi-kinase inhibitor with antiangiogenic activity, may cause organ perforation. We present a case of pneumothorax during lenvatinib plus pembrolizumab (LP) therapy for endometrial cancer.</div></div><div><h3>Case report</h3><div>A 63-year-old woman with stage 1A endometrioid adenocarcinoma underwent hysterectomy, bilateral adnexectomy, and pelvic lymphadenectomy, followed by radiation therapy. Owing to multiple lung and pleural metastases, she underwent thoracoscopic partial resection of the right lung, followed by adriamycin and cisplatin chemotherapy; however, the residual tumors still progressed. LP was then administered, and stable disease was obtained. Seven months after LP introduction, she presented with epigastric pain, thereafter diagnosed with right-lung pneumothorax. After chest tube placement and pleurodesis, lenvatinib was restarted at a reduced dose. Subsequently, the pneumothorax did not recur.</div></div><div><h3>Conclusion</h3><div>This case highlights the possibility of pneumothorax during LP therapy, especially in patients with lung metastases in contact with the pleura.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 5","pages":"Pages 865-867"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mismatch repair (MMR) status detection is the first step for endometrial cancer patients","authors":"Peng-Hui Wang, Szu-Ting Yang, Wen-Hsun Chang","doi":"10.1016/j.tjog.2025.07.018","DOIUrl":"10.1016/j.tjog.2025.07.018","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 5","pages":"Pages 770-772"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"When is induction truly a failure? Toward a more accurate definition","authors":"Chia-Hao Liu, Wei-Ting Chao, Peng-Hui Wang","doi":"10.1016/j.tjog.2025.07.015","DOIUrl":"10.1016/j.tjog.2025.07.015","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 5","pages":"Pages 763-764"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}