Taiwanese Journal of Obstetrics & Gynecology最新文献

{"title":"Association between gestation weight gain and postpartum poor sleep quality in postpartum women with weight retention","authors":"Ling Lim ,&nbsp;Chu-Yi Chou ,&nbsp;Tzu-Ling Chen ,&nbsp;Chia-Sui Weng","doi":"10.1016/j.tjog.2024.03.035","DOIUrl":"10.1016/j.tjog.2024.03.035","url":null,"abstract":"<div><h3>Objective</h3><div>Gestational weight gain (GWG) and sleep quality may cause postpartum weight retention (PPWR).</div></div><div><h3>Materials and methods</h3><div>This was a cross-sectional study conducted from January to October 2022. A total of 282 postpartum women were recruited at 6 months postpartum, at which point postpartum weight was measured in our obstetrics and gynecology clinic. We classified participants into the two categories of excessive PPWR (≥5 kg) at 6 months postpartum or those without it. GWG was obtained from maternal health records. Weight gain during pregnancy was described as “insufficient” if below the Institute of Medicine recommendations (2009), “adequate” if within the recommended range, and “excessive” if above the recommendation. The Pittsburgh Sleep Quality Index was used to assess sleep during the previous 7 days.</div></div><div><h3>Results</h3><div>Participants’ mean age was 36.1 ± 5.2 years. Poor sleep quality (OR: 10.9; 95 % CI: 4.04–29.49) was associated with excessive PPWR. Women with insufficient GWG (OR: 0.34; 95 % CI: 0.17–0.65) were less likely to reach substantial PPWR (OR: 0.51; 95 % CI: 0.26–0.98), while those with excessive GWG were more likely to do so (OR: 7.25; 95 % CI: 2.66–19.75).</div></div><div><h3>Conclusion</h3><div>Health-care providers should recognize that encouraging appropriate GWG and the screening for sleep quality of postpartum women may reduce the incidence of substantial PPWR and thus reduce obesity rates in the early postpartum period.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 477-481"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between ovarian reserve and organophosphate flame retardants in women of childbearing age","authors":"Hao-Ting Lien ,&nbsp;Yu-Che Ou ,&nbsp;Yin-Hua Cheng ,&nbsp;Chia-Te Kung ,&nbsp;Yung-Chiao Chang ,&nbsp;Pei-Ling Weng ,&nbsp;Kuo-Chung Lan","doi":"10.1016/j.tjog.2024.11.012","DOIUrl":"10.1016/j.tjog.2024.11.012","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the association between organophosphate flame retardants (OPFRs) and ovarian reserve in women of childbearing age.</div></div><div><h3>Materials and methods</h3><div>In this Cross-sectional study, the participants were recruited from August 2020 to October 2022 at the outpatient department of Obstetrics and Gynecology in Chang Gung Memorial Hospital, Kaohsiung Medical Center in Taiwan. The inclusion criteria were as follows: adult women of childbearing age were eligible to participate. Old age (&gt;50 years old), patients using antidepressants and antipsychotics for over months were excluded. We measured the urinary concentrations of 10 OPFR compounds to assess exposure patterns and compared the clinical and urinary OPFR profiles among subgroups to determine whether these OPFR compounds were independently correlated with AMH, FSH, and LH levels. Environmental and lifestyle factors were assessed using questionnaires to determine the risk factors for OPFR exposure.</div></div><div><h3>Results</h3><div>Total 99 participants were enrolled in our study. after adjusting for covariates, higher urinary concentrations of bis(1,3-dichloro-2-propyl) phosphate (BDCPP) and diphenyl phosphate (DPHP) were predictors of the lower AMH subgroup compared to the high AMH subgroup (low vs. high AMH (cut-off value: 1.5 ng/mL), odds ratio (OR) (95 % confidence interval (CI)), 5.714 (1.435–22.727), p = 0.007; 4.149 (1.004–17.241), p = 0.037, respectively). FSH and LH levels were not significantly associated with the 10 OPFRs in our study.</div></div><div><h3>Conclusion</h3><div>Our study revealed that OPFR exposure was widespread among women of childbearing age, with a 100 % detection rate in urinary samples. Additionally, higher urinary concentrations of BDCPP and DPHP were predictors of the lower AMH subgroup compared to the high AMH subgroup. Further research is required to gain a deeper understanding of the exposure patterns and potential reproductive toxicity of OPFRs in women of childbearing age.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 504-511"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental detection of a 1.61-Mb familial Xp22.31 microdeletion encompassing PUDP, STS, VCX and PNPLA4 in a male fetus with cleft lip and palate on prenatal ultrasound and a favorable postnatal outcome","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.03.005","DOIUrl":"10.1016/j.tjog.2025.03.005","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 542-543"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of 3D laparoscopy in gynecology","authors":"Chyi-Long Lee","doi":"10.1016/j.tjog.2025.03.003","DOIUrl":"10.1016/j.tjog.2025.03.003","url":null,"abstract":"<div><div>The advent of three-dimensional (3D) laparoscopy has brought significant advancements in surgical techniques and outcomes in gynecology. This review synthesizes findings from recent studies comparing 3D laparoscopy with traditional two-dimensional (2D) methods. It highlights the advantages, challenges, and clinical outcomes associated with the adoption of 3D technology in gynecological surgeries. Key benefits of 3D laparoscopy include enhanced depth perception and spatial orientation, which lead to improved surgical precision and shorter learning curves for surgeons. Studies have demonstrated that 3D laparoscopy results in reduced operative times, less blood loss, and quicker recovery periods. Moreover, it offers significant advantages in complex procedures such as endometriosis excision and urogynecological surgeries. However, the ergonomic challenges and higher costs associated with 3D systems remain barriers to widespread adoption. Comparative studies have shown that 3D laparoscopy can be a cost-effective alternative to robotic systems, providing similar clinical outcomes. Training with 3D technology has been shown to enhance skill acquisition among trainee surgeons, suggesting that its integration into surgical training programs could be highly beneficial. Despite its advantages, further research is needed to address the ergonomic concerns and to explore the long-term cost-effectiveness of 3D laparoscopy in routine clinical practice. This review underscores the potential of 3D laparoscopy to become a standard approach in gynecological surgery, provided that ongoing technological and ergonomic improvements are made.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 434-437"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complete remission of endometrial cancer stage IVC treated with multimodality treatment including immunotherapy and maintenance PARP inhibitor – A case report","authors":"You-Yan Chen ,&nbsp;Feng-Yuan Liu ,&nbsp;Yin-Yin Chiang ,&nbsp;Chyong-Huey Lai","doi":"10.1016/j.tjog.2024.12.027","DOIUrl":"10.1016/j.tjog.2024.12.027","url":null,"abstract":"<div><h3>Objective</h3><div>Mismatched repair (MMR) deficient, stage IVC endometrial carcinoma (EC) are occasionally reported as cured by immune-checkpoint inhibitors (ICIs). We present an MMR proficient (MMRp) case with long-term survival.</div></div><div><h3>Case report</h3><div>The patient was diagnosed with EC (endometrioid, grade 3, MMRp, programmed death-ligand 1 positive) stage IVC (lung, spine/pelvic bone, paraaortic, pelvic, inguinal and presacral node metastases) with tumor extended from endometrium to cervix, vagina to vulva. After responded to chemoimmunotherapy with paclitaxel/carboplatin then liposomal doxorubicin/carboplatin, pembrolizumab and radiotherapy to pelvis/pelvic bone metastasis, the patient received definitive surgery which showed only residual EC. Olaparib was used as maintenance therapy. The patient developed isolated recurrence in presacral lymph node 2.5 years later, she underwent proton therapy and got complete remission again and maintained with olaparib. She is currently without disease 31 months since recurrence.</div></div><div><h3>Conclusion</h3><div>Initial stage IVC MMRp EC with recurrence is still potentially curable with multimodality treatment including ICI.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 524-527"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The new hope to manage women with mismatch repair proficient endometrial cancer","authors":"Peng-Hui Wang ,&nbsp;Jen-Ruei Chen ,&nbsp;Byoung-Gie Kim","doi":"10.1016/j.tjog.2025.03.002","DOIUrl":"10.1016/j.tjog.2025.03.002","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 410-412"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between exposure to volatile organic compounds and female infertility: An NHANES analysis","authors":"Liang-Sien Chen ,&nbsp;Hung-Keng Wu ,&nbsp;Wen-Hsin Chang ,&nbsp;Wei-Chu Wang ,&nbsp;Chyi-Huey Bai","doi":"10.1016/j.tjog.2024.05.029","DOIUrl":"10.1016/j.tjog.2024.05.029","url":null,"abstract":"<div><h3>Objective</h3><div>Infertility affects a large portion of the global population, with environmental, lifestyle, and biological factors contributing to its incidence. Volatile organic compounds (VOCs) are widely used in consumer products, and are considered environmental pollutants and are associated with various adverse health outcomes. However, their impact on female fertility remains unclear. This study investigated the relation between urinary VOC metabolite levels and infertility in women.</div></div><div><h3>Materials and methods</h3><div>This cross-sectional analysis utilized data from the National Health and Nutrition Examination Survey (NHANES) for the years 2013–2018. Female participants 18–45 years old with reproductive health data were included. Infertility status was determined through questionnaire responses, and urinary VOC metabolite levels were obtained from the NHANES laboratory data. The associations between VOC levels and infertility were assessed through univariate and multivariable regression analyses.</div></div><div><h3>Results</h3><div>Of the 29,400 female participants in the NHANES data set, 1097 women met the inclusion criteria. Multivariable analysis adjusted for confounders showed significant associations between 12 specific VOC metabolites and an increased likelihood of infertility, with N-Acetyl-S-(3,4-dihydroxybutyl)-<span>l</span>-cysteine (DHBMA) (adjusted odds ratio [aOR] = 1.48, 95 % confidence interval [CI]: 1.04–2.12, p = 0.030) and N-Acetyl-S-(2-hydroxypropyl)-<span>l</span>-cysteine (2HPMA) (aOR = 1.41, 95 % CI:1.07–1.85, p = 0.016) showing the strongest associations.</div></div><div><h3>Conclusions</h3><div>Our study highlights a significant association between specific urinary VOC metabolites and an increased likelihood of infertility in women. While causality cannot be conclusively determined, the findings offer an initial insight into the reproductive health risks linked to VOC exposure.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 493-498"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometrial cancer: Part II. Multimodality treatment of uterine high-grade serous carcinoma (clinical course I)","authors":"Che-Wei Chang ,&nbsp;Szu-Ting Yang ,&nbsp;Chia-Hao Liu ,&nbsp;Wen-Hsun Chang ,&nbsp;Wen-Ling Lee ,&nbsp;Peng-Hui Wang","doi":"10.1016/j.tjog.2024.03.034","DOIUrl":"10.1016/j.tjog.2024.03.034","url":null,"abstract":"<div><div>Endometrial cancer (EC) is the most frequently diagnosed gynecological malignancy with rapid growth of incidence in the high-income countries and Taiwan. Since the integration of modern molecular pathology into traditional clinico-pathology for the diagnosis and classification of EC, the treatment is apparently switched to more precise molecular-guided or -targeted therapy, having been reviewed in the part I (2022). The current review is the part II describing the previous history (clinical course I) of the complex clinical course occurred in a 66-year-old woman with uterine high-grade serous carcinoma (HGSC, post-curettage diagnosis), who was treated with robotic staging surgery without additional postoperative adjuvant therapy due to absence of any residual malignancy in February 2019 (Rationales and controversial issues 1–5). Recurrences at the multiple sites, including vaginal cuff, liver, adrenal and lung metastases occurred in December 2020. Suboptimal cytoreductive surgery and following 6 cycles of paclitaxel-carboplatin regimen between January and April 2021 achieved nearly complete remission (Rationales 6,7 and controversial issues 6,7 for the first recurrence). However, this equivocal clinical situation made the following treatment in confusion. Using positron emission tomography/magnetic resonance image (MRI) or computed tomography (CT) not only serving as a valuable tool for detecting occult metastatic lesions but also giving an answer for uncertain clinical diagnosis provided the additional therapy (Rationales 8–10 and Controversial issues 7–9). This case highlights an aggressive nature of uterine HGSC, even though the initial diagnosis was an early-stage disease (no residual tumor) and the hospital shopping makes the clinical course much complex. This part II (Clinical course I) has explored the first journey from the initial diagnosis and initial treatment at the hospital “A” and “B” to the subsequent management of the recurrent disease at the hospitals “C,D,E,F”, including the rationale and controversial issues in the clinical course I.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 413-424"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invisible demerits of ChatGPT in medical writing","authors":"Shigeki Matsubara,&nbsp;Daisuke Matsubara","doi":"10.1016/j.tjog.2025.01.005","DOIUrl":"10.1016/j.tjog.2025.01.005","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 581-582"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis of a 4p16.3 microdeletion and a 11p15.5p15.4 microduplication in a fetus with increased nuchal translucency. Dandy-Walker malformation and intrauterine growth restriction","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.03.013","DOIUrl":"10.1016/j.tjog.2025.03.013","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 571-575"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}