Taiwanese Journal of Obstetrics & Gynecology最新文献

{"title":"Low-level mosaic trisomy 6 at amniocentesis associated with a favorable fetal outcome and complete cytogenetic discrepancy between cultured amniocytes and uncultured amniocytes","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2024.12.025","DOIUrl":"10.1016/j.tjog.2024.12.025","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 392-393"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis and molecular cytogenetic characterization of mosaicism for r(10) and monosomy 10 at amniocentesis in a fetus associated with perinatal growth restriction but no gross structural abnormalities","authors":"Chih-Ping Chen ,&nbsp;Fang-Tzu Wu ,&nbsp;Yen-Ting Pan ,&nbsp;Peih-Shan Wu ,&nbsp;Meng-Shan Lee ,&nbsp;Chen-Wen Pan ,&nbsp;Wayseen Wang","doi":"10.1016/j.tjog.2024.12.012","DOIUrl":"10.1016/j.tjog.2024.12.012","url":null,"abstract":"<div><h3>Objective</h3><div>We present prenatal diagnosis and molecular cytogenetic characterization of mosaicism for r(10) and monosomy 10 at amniocentesis in a fetus with a 10p15.3 microdeletion and a 10q26.3 microdeletion.</div></div><div><h3>Case report</h3><div>A 37-year-old, gravida 2, para 1, woman underwent amniocentesis at 17 weeks of gestation because of advanced maternal age. Amniocentesis revealed a karyotype of 45,XX, −10[11]/46,XX,r(10)[6]. Prenatal ultrasound was normal. She was referred for genetic counseling, and repeat amniocentesis at 21 weeks of gestation revealed a karyotype of 46,XX,r(10)[15]/45,XX,-10[5]. The parental karyotypes were normal. Simultaneous array comparative genomic hybridization (aCGH) analysis on the DNA extracted from uncultured amniocytes revealed a 2.182-Mb 10p15.3 deletion encompassing the genes of <em>ZMYND11</em> and <em>DIP2C</em>, and a 2.257-Mb 10q26.3 deletion outside the genes of <em>DOCK1</em> and <em>EBF3</em>. Prenatal ultrasound showed intrauterine growth restriction but no gross structural abnormalities. The parents elected to continue the pregnancy, and a 2425-g baby was delivered at 40 weeks of gestation without craniofacial dysmorphism. The cord blood had a karyotype of 46,XX,r(10)[29]/45,XX,-10[9]/47,XX,r(10),+r(10)[1]/46,XX[1]. When follow-up at age four months, the peripheral blood had a karyotype of 46,XX,r(10) [32]/45,XX,-10[8], her body weight was 5.1 Kg (&lt;3 centile), and body height was 58 cm (&lt;3 centile). She did not have craniofacial dysmorphism. When follow-up at age one year and two months, her body weight was 5.9 Kg (&lt;3 centile), and body height was 68.5 cm (&lt;3 centile). She manifested motor and speech developmental delay but no hypotonia. Brain computed tomography and whole-body ultrasound examination showed no abnormalities.</div></div><div><h3>Conclusion</h3><div>Mosaicism for r(10) and monosomy 10 at prenatal diagnosis can be associated with perinatal growth restriction but no gross structural abnormalities.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 339-344"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally invasive surgery for earl-stage cervical cancer","authors":"Peng-Hui Wang,&nbsp;Brahmana Askandar Tjokroprawiro,&nbsp;Szu-Ting Yang","doi":"10.1016/j.tjog.2024.12.004","DOIUrl":"10.1016/j.tjog.2024.12.004","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 213-215"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overcoming extensive abdominal adhesions: Utilizing mini-wound techniques for successful laparoscopic staging in cancer surgery","authors":"Kai-Chung Huang ,&nbsp;Yu-Ting Lin ,&nbsp;Wen-Hsun Chang ,&nbsp;Szu-Ting Yang ,&nbsp;Peng-Hui Wang","doi":"10.1016/j.tjog.2025.01.002","DOIUrl":"10.1016/j.tjog.2025.01.002","url":null,"abstract":"<div><h3>Objective</h3><div>Using an ultra-mini-wound technique to dissect the adhesion surrounding the umbilicus port site aiding laparoscopic staging surgery for treating a woman with an early-stage endometrioid endometrial cancer (E-EC) who had widespread and extensive abdominal adhesions secondary to the previous complicated cesarean section (C/S) and bladder rupture.</div></div><div><h3>Case Report</h3><div>A 70-year-old woman with a history of a previous C/S and complicating bladder rupture treated with the Boari flap repair, leaving a longitudinal depressed scar over the abdomen from the umbilicus site to pubic hair area in her 30s was scheduled for laparoscopic staging surgery due to early-stage E-EC. We performed an ultra-mini midline incision (3-cm) crossing the umbilicus to manually dissect the adhesion surrounding the umbilicus and inserted the main trocar port to establish the workplace for further laparoscopic staging surgery. Additionally, malposition of the right ureter (passing through the dome of the abdominal cavity) secondary to previous Boari flap repair for ruptured urinary bladder was clearly identified. Surgery was completed and uneventful. The patient was discharged on the day 4 with a total length of hospital stay of four days. She is living well and freeing of disease and sequelae.</div></div><div><h3>Conclusion</h3><div>An ultra-mini wound assisted laparoscopic surgery can be successfully applied in women with an extensive and widespread abdominal adhesion without increasing adverse events or prolonging length of hospital stay.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 364-367"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis of a familial 21q22.3 microduplication encompassing part of Down syndrome critical region in a pregnancy associated with an asymptomatic mother carrier without Down syndrome phenotype","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2024.12.020","DOIUrl":"10.1016/j.tjog.2024.12.020","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 383-384"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The new era of risk assessment for hypertension in pregnancy: From clinical to biochemical markers in a comprehensive predictive model","authors":"Liju Nie ,&nbsp;Ziyu Zhang ,&nbsp;Qinglan Yao ,&nbsp;Huayan Chen ,&nbsp;Chao Xu ,&nbsp;Lin Chen ,&nbsp;Chengcheng Liu ,&nbsp;Lantao Tu ,&nbsp;Yuping Yi ,&nbsp;Tianqiang Huang ,&nbsp;Xiaoming Zeng ,&nbsp;Lamei Yu","doi":"10.1016/j.tjog.2024.10.014","DOIUrl":"10.1016/j.tjog.2024.10.014","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to develop and validate a model based on the weighted random forest (WRF) algorithm to predict early-onset preeclampsia (PE) and to assess the importance of various clinical and biochemical markers in early risk identification.</div></div><div><h3>Materials and methods</h3><div>This study was conducted at the Jiangxi Maternal and Child Health Hospital and involved 12,699 pregnant women from January 2019 to June 2022. Extensive clinical and biochemical markers were collected through prenatal care data, which were used to construct a predictive model for early-onset PE. The model was developed using the WRF and Logistic regression methods, and multivariable analysis was employed to identify markers significantly associated with the risk of PE.</div></div><div><h3>Results</h3><div>The relative importance of various markers was evaluated using the random forest (RF) model in a sample of 1200 patients diagnosed with PE. Blood pressure and pre-pregnancy body mass index (BMI) were identified as the most critical variables affecting the accuracy of the PE prediction model. The WRF model demonstrated higher predictive accuracy (AUC = 0.9614) than the Logistic regression model (AUC = 0.9138), highlighting its superiority in early risk identification for PE.</div></div><div><h3>Conclusion</h3><div>The WRF-based predictive model developed in this study effectively predicts the risk of early-onset PE, with blood pressure and BMI as vital predictive factors. These findings underscore the importance of employing a comprehensive predictive model for risk assessment in early pregnancy, facilitating early intervention and improving health outcomes for pregnant women and their newborns.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 253-264"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in sexually transmitted infection-associated cervical infections in pelvic inflammatory disease patients between adolescents and adults","authors":"Jung Mi Byun ,&nbsp;Dae Hoon Jeong ,&nbsp;Young Nam Kim ,&nbsp;Do Hwa Im ,&nbsp;Da Hyun Kim ,&nbsp;Eun Jeong Jeong ,&nbsp;Eunhye Cho ,&nbsp;Kyung Bok Lee","doi":"10.1016/j.tjog.2024.10.015","DOIUrl":"10.1016/j.tjog.2024.10.015","url":null,"abstract":"<div><h3>Objective</h3><div>Pelvic inflammatory disease (PID) is an infection of female reproductive organs mainly in sexually active patients, which can cause serious complications throughout life. We aimed to analyze the risk factors and differences in sexually transmitted infections (STIs) between adolescents and adult PID patients.</div></div><div><h3>Materials and methods</h3><div>We conducted a retrospective study based on descriptive and statistical analyses of the clinical records of patients with PID treated with antibiotics between January 2013 and December 2023 at Busan Paik Hospital. In this study, we analyzed the clinical characteristics of patients and the types of cultured bacteria in vaginal discharge, as well as their association with STIs according to age.</div></div><div><h3>Results</h3><div>Three hundred patients required hospitalization and treatment with antibiotics. Thirty-nine (13.0 %) were adolescent patients, and 261 (87 %) were adult patients. Infections of <em>Chlamydia trachomatis</em>, <em>Neisseria gonorrhoeae</em>, <em>Mycoplasma genitalium</em>, <em>Mycoplasma hominis</em>, <em>Ureaplasma urealyticum,</em> and <em>Trichomonas vaginalis</em> were more prevalent in adolescents than in adult patients (<em>P</em> &lt; 0.001, 0.001, 0.013, &lt;0.001, 0.004 and 0.010, respectively)<em>.</em> Although <em>Lactobacillus spp</em>. was predominant among the cultured strains in both adolescents and adults, it was detected in 29.6 % of adolescent patients and 48.4 % of adults; its detection rates were relatively lower among adolescents (<em>P</em> = 0.071). Among adolescents, 30.6 % were smokers, while 13.3 % were smokers among adult patients. Although there was a higher prevalence of smoking among adolescents, the statistical analysis did not show a significant difference in smoking prevalence between adolescents and adults (<em>P</em> = 0.08).</div></div><div><h3>Conclusion</h3><div>In this study, adolescents with PID exhibited a higher prevalence of STIs compared to adults. Additionally, One-third of these adolescents were smokers and did not use barrier protection. PID in adolescents has distinct risk factors, causative bacteria, and clinical features compared to adults. Hence, it is crucial to develop effective strategies for treating and preventing STIs in this population.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 265-271"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum hemorrhage (PPH)","authors":"Yiu-Tai Li,&nbsp;Szu-Ting Yang,&nbsp;Peng-Hui Wang","doi":"10.1016/j.tjog.2024.12.005","DOIUrl":"10.1016/j.tjog.2024.12.005","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 216-218"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis of familial 46,X,del(X)(q27.1) with an Xq27.1-q28 deletion and an Xp22.33 microduplication in an asymptomatic mother carrier","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2024.12.017","DOIUrl":"10.1016/j.tjog.2024.12.017","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 375-378"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel technique with cool-tip radiofrequency ablation for selective fetal reduction in complicated monochorionic twin","authors":"Ting Yi Chu ,&nbsp;Chih-Ping Chen ,&nbsp;Pei-Chen Chen ,&nbsp;Yu-Chen Chien ,&nbsp;Hsing-Tse Yu ,&nbsp;Liang-Ming Lo ,&nbsp;T'sang-T'ang Hsieh ,&nbsp;Steven W. Shaw","doi":"10.1016/j.tjog.2024.11.007","DOIUrl":"10.1016/j.tjog.2024.11.007","url":null,"abstract":"<div><h3>Objective</h3><div>To invent a novel method for selective fetal reduction in monochorionic (MC) twin using cool-tip radiofrequency ablation (RFA) and analysis the perinatal outcome.</div></div><div><h3>Material and methods</h3><div>Complicated MC twins including twin-to twin transfusion syndrome (TTTS), selective fetal growth restriction (sFGR) and twin reverse arterial perfusion sequence (TRAP) were enrolled from 2020 to 2024. All cases were indicated for selective fetal reduction due to expected poor outcome. Equilateral triangle method using single puncture 4 times ablation with 17G cool-tip RFA to cord insertion site, umbilical vein and two umbilical arteries for complete stopping the blood flow. The power was starting from 60 W, 80 W, 80 W and 100 W 1 min each site. Outcome were analyzed.</div></div><div><h3>Results</h3><div>A total of 51 cases were collected and treated in a single medical center. We divided first 20 cases as tradition group using single point ablation and novel 4-point ablation group after 21st cases. The overall co-twin survival rate after RFA procedure was 88 % (45 out of 51) in whole series. However, the co-twin survival rate in the novel 4-point group was better than single point group (93.5 % vs 80 %) with statistically significance. The maternal age, procedure at gestational age, procedure time and preterm birth rate did not show statistically difference between two groups.</div></div><div><h3>Conclusions</h3><div>This novel equilateral triangle method to stop all the umbilical blood flow achieved the high successful rate without maternal complication. The 17 g cool-tip RFA worked at low temperature to avoid thermal damage. This might be the new choice of RFA in monochorionic pregnancies.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 2","pages":"Pages 298-302"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}