Taiwanese Journal of Obstetrics & Gynecology最新文献

{"title":"Complex tumor microenvironment of endometrial cancer","authors":"Szu-Ting Yang, Che-Wei Chang, Peng-Hui Wang","doi":"10.1016/j.tjog.2024.03.033","DOIUrl":"10.1016/j.tjog.2024.03.033","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 407-409"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous rupture of left common iliac artery after cesarean section: A rare case of hypovolemic shock in Obstetrics","authors":"FengXiang Yao, LinLin Wang, Li Wang, LiangLiang Xiao, YanQing Qi","doi":"10.1016/j.tjog.2024.11.011","DOIUrl":"10.1016/j.tjog.2024.11.011","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 583-585"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis of geleophysic dysplasia with ADAMTSL2 mutations","authors":"Yu-Ting Jiang ,&nbsp;Shao-Bin Lin ,&nbsp;Cai-Xin Huang ,&nbsp;Liu Du ,&nbsp;Hong-Ning Xie","doi":"10.1016/j.tjog.2024.10.021","DOIUrl":"10.1016/j.tjog.2024.10.021","url":null,"abstract":"<div><h3>Objectives</h3><div>We present prenatal diagnosis of Geleophysic dysplasia (GD) at 22 weeks gestation with prenatal ultrasound findings, molecular genetic analysis and postmortem examination.</div></div><div><h3>Case report</h3><div>A 27-year-old primigravida was referred at 22 + 4 weeks gestation for detailed anomaly scanning due to routine ultrasound detection of short limbs. Chorionic villus sampling followed by family-based whole-exome sequencing identified two missense ADAMTSL2 variants, both classified as variants of uncertain significance. Detailed ultrasound screening showed short limbs, small hands and feet, typical facial appearance, cardiac and pulmonary anomalies. The association of phenotype and genotype support the diagnosis of GD. Postmortem examination confirmed the prenatal ultrasound findings and the diagnosis of GD.</div></div><div><h3>Conclusion</h3><div>Two missense ADAMTSL2 variants in this case may add new evidence to the molecular diagnosis of GD. Prenatal ultrasound assessment of the fetal phenotype helps us to better interpret fetal genotype, and find the potential causative variants.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 528-530"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis of SRY(+) 45,X male and the confirmation of high-level mosaicism for 45,X in 45,X/46,X,del(Y) (q11.222) in a fetus with a favorable fetal outcome and perinatal progressive decrease of the 45,X cell line","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.03.006","DOIUrl":"10.1016/j.tjog.2025.03.006","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 544-550"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between gestation weight gain and postpartum poor sleep quality in postpartum women with weight retention","authors":"Ling Lim ,&nbsp;Chu-Yi Chou ,&nbsp;Tzu-Ling Chen ,&nbsp;Chia-Sui Weng","doi":"10.1016/j.tjog.2024.03.035","DOIUrl":"10.1016/j.tjog.2024.03.035","url":null,"abstract":"<div><h3>Objective</h3><div>Gestational weight gain (GWG) and sleep quality may cause postpartum weight retention (PPWR).</div></div><div><h3>Materials and methods</h3><div>This was a cross-sectional study conducted from January to October 2022. A total of 282 postpartum women were recruited at 6 months postpartum, at which point postpartum weight was measured in our obstetrics and gynecology clinic. We classified participants into the two categories of excessive PPWR (≥5 kg) at 6 months postpartum or those without it. GWG was obtained from maternal health records. Weight gain during pregnancy was described as “insufficient” if below the Institute of Medicine recommendations (2009), “adequate” if within the recommended range, and “excessive” if above the recommendation. The Pittsburgh Sleep Quality Index was used to assess sleep during the previous 7 days.</div></div><div><h3>Results</h3><div>Participants’ mean age was 36.1 ± 5.2 years. Poor sleep quality (OR: 10.9; 95 % CI: 4.04–29.49) was associated with excessive PPWR. Women with insufficient GWG (OR: 0.34; 95 % CI: 0.17–0.65) were less likely to reach substantial PPWR (OR: 0.51; 95 % CI: 0.26–0.98), while those with excessive GWG were more likely to do so (OR: 7.25; 95 % CI: 2.66–19.75).</div></div><div><h3>Conclusion</h3><div>Health-care providers should recognize that encouraging appropriate GWG and the screening for sleep quality of postpartum women may reduce the incidence of substantial PPWR and thus reduce obesity rates in the early postpartum period.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 477-481"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the enigma of shoulder pain post laparoscopic surgery: exploring influencing factors and recovery trajectories","authors":"Pei-Shan Lee ,&nbsp;Chyi-Long Lee","doi":"10.1016/j.tjog.2024.06.016","DOIUrl":"10.1016/j.tjog.2024.06.016","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the recovery trajectories of shoulder pain after gynecological laparoscopic surgery and identify the factors influencing its occurrence.</div></div><div><h3>Materials and methods</h3><div>A longitudinal research design with repeated tests was employed using self-administered questionnaires and visual analogue scales of pain. In a tertiary center, a total of 97 participants who underwent gynecological laparoscopic benign surgery were recruited. The data were analyzed using independent t-tests, chi-squared tests, and generalized estimating equations (GEE) in SPSS for Windows Version 15.0. A two-tailed p-value &lt;.05 was considered statistically significant.</div></div><div><h3>Results</h3><div>The prevalence of shoulder pain after gynecological laparoscopic surgery was 77.3 %, with a higher incidence of pain reported on the right side (58.7 %). Several factors were found to influence shoulder pain after gynecological laparoscopic surgery, including the operation time and use of analgesic (p = .01). Furthermore, postoperative shoulder pain demonstrated a significant negative correlation with pain satisfaction (p &lt; .01) and a significant positive correlation with the use of analgesic injections (p = .05). The shoulder pain score decreased at 24 h after surgery and reached its lowest point at 36 h after surgery (P &lt; .01).</div></div><div><h3>Conclusions</h3><div>Following gynecological laparoscopic surgery, 77.3 % of patients suffered from shoulder pain, correlating with longer operation times and increased analgesic use. Shoulder pain tended to peak at 12 h post-surgery. Effective pain relief strategies can significantly improve pain management for minimally invasive therapy, enhancing patient satisfaction and recovery outcomes.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 482-486"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between ovarian reserve and organophosphate flame retardants in women of childbearing age","authors":"Hao-Ting Lien ,&nbsp;Yu-Che Ou ,&nbsp;Yin-Hua Cheng ,&nbsp;Chia-Te Kung ,&nbsp;Yung-Chiao Chang ,&nbsp;Pei-Ling Weng ,&nbsp;Kuo-Chung Lan","doi":"10.1016/j.tjog.2024.11.012","DOIUrl":"10.1016/j.tjog.2024.11.012","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the association between organophosphate flame retardants (OPFRs) and ovarian reserve in women of childbearing age.</div></div><div><h3>Materials and methods</h3><div>In this Cross-sectional study, the participants were recruited from August 2020 to October 2022 at the outpatient department of Obstetrics and Gynecology in Chang Gung Memorial Hospital, Kaohsiung Medical Center in Taiwan. The inclusion criteria were as follows: adult women of childbearing age were eligible to participate. Old age (&gt;50 years old), patients using antidepressants and antipsychotics for over months were excluded. We measured the urinary concentrations of 10 OPFR compounds to assess exposure patterns and compared the clinical and urinary OPFR profiles among subgroups to determine whether these OPFR compounds were independently correlated with AMH, FSH, and LH levels. Environmental and lifestyle factors were assessed using questionnaires to determine the risk factors for OPFR exposure.</div></div><div><h3>Results</h3><div>Total 99 participants were enrolled in our study. after adjusting for covariates, higher urinary concentrations of bis(1,3-dichloro-2-propyl) phosphate (BDCPP) and diphenyl phosphate (DPHP) were predictors of the lower AMH subgroup compared to the high AMH subgroup (low vs. high AMH (cut-off value: 1.5 ng/mL), odds ratio (OR) (95 % confidence interval (CI)), 5.714 (1.435–22.727), p = 0.007; 4.149 (1.004–17.241), p = 0.037, respectively). FSH and LH levels were not significantly associated with the 10 OPFRs in our study.</div></div><div><h3>Conclusion</h3><div>Our study revealed that OPFR exposure was widespread among women of childbearing age, with a 100 % detection rate in urinary samples. Additionally, higher urinary concentrations of BDCPP and DPHP were predictors of the lower AMH subgroup compared to the high AMH subgroup. Further research is required to gain a deeper understanding of the exposure patterns and potential reproductive toxicity of OPFRs in women of childbearing age.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 504-511"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental detection of a 1.61-Mb familial Xp22.31 microdeletion encompassing PUDP, STS, VCX and PNPLA4 in a male fetus with cleft lip and palate on prenatal ultrasound and a favorable postnatal outcome","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2025.03.005","DOIUrl":"10.1016/j.tjog.2025.03.005","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 542-543"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of 3D laparoscopy in gynecology","authors":"Chyi-Long Lee","doi":"10.1016/j.tjog.2025.03.003","DOIUrl":"10.1016/j.tjog.2025.03.003","url":null,"abstract":"<div><div>The advent of three-dimensional (3D) laparoscopy has brought significant advancements in surgical techniques and outcomes in gynecology. This review synthesizes findings from recent studies comparing 3D laparoscopy with traditional two-dimensional (2D) methods. It highlights the advantages, challenges, and clinical outcomes associated with the adoption of 3D technology in gynecological surgeries. Key benefits of 3D laparoscopy include enhanced depth perception and spatial orientation, which lead to improved surgical precision and shorter learning curves for surgeons. Studies have demonstrated that 3D laparoscopy results in reduced operative times, less blood loss, and quicker recovery periods. Moreover, it offers significant advantages in complex procedures such as endometriosis excision and urogynecological surgeries. However, the ergonomic challenges and higher costs associated with 3D systems remain barriers to widespread adoption. Comparative studies have shown that 3D laparoscopy can be a cost-effective alternative to robotic systems, providing similar clinical outcomes. Training with 3D technology has been shown to enhance skill acquisition among trainee surgeons, suggesting that its integration into surgical training programs could be highly beneficial. Despite its advantages, further research is needed to address the ergonomic concerns and to explore the long-term cost-effectiveness of 3D laparoscopy in routine clinical practice. This review underscores the potential of 3D laparoscopy to become a standard approach in gynecological surgery, provided that ongoing technological and ergonomic improvements are made.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 434-437"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complete remission of endometrial cancer stage IVC treated with multimodality treatment including immunotherapy and maintenance PARP inhibitor – A case report","authors":"You-Yan Chen ,&nbsp;Feng-Yuan Liu ,&nbsp;Yin-Yin Chiang ,&nbsp;Chyong-Huey Lai","doi":"10.1016/j.tjog.2024.12.027","DOIUrl":"10.1016/j.tjog.2024.12.027","url":null,"abstract":"<div><h3>Objective</h3><div>Mismatched repair (MMR) deficient, stage IVC endometrial carcinoma (EC) are occasionally reported as cured by immune-checkpoint inhibitors (ICIs). We present an MMR proficient (MMRp) case with long-term survival.</div></div><div><h3>Case report</h3><div>The patient was diagnosed with EC (endometrioid, grade 3, MMRp, programmed death-ligand 1 positive) stage IVC (lung, spine/pelvic bone, paraaortic, pelvic, inguinal and presacral node metastases) with tumor extended from endometrium to cervix, vagina to vulva. After responded to chemoimmunotherapy with paclitaxel/carboplatin then liposomal doxorubicin/carboplatin, pembrolizumab and radiotherapy to pelvis/pelvic bone metastasis, the patient received definitive surgery which showed only residual EC. Olaparib was used as maintenance therapy. The patient developed isolated recurrence in presacral lymph node 2.5 years later, she underwent proton therapy and got complete remission again and maintained with olaparib. She is currently without disease 31 months since recurrence.</div></div><div><h3>Conclusion</h3><div>Initial stage IVC MMRp EC with recurrence is still potentially curable with multimodality treatment including ICI.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 3","pages":"Pages 524-527"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}