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Naproxen-induced liver injury in a case of adult-onset Still's disease. 一例成人型斯蒂尔病患者因萘普生引起的肝损伤。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-09-30 DOI: 10.1177/00494755241287261
Suresh Selvam, Ankita Bansal, Harpreet Singh, Deba Prasad Dhibhar, Vikas Suri, Ashish Bhalla
{"title":"Naproxen-induced liver injury in a case of adult-onset Still's disease.","authors":"Suresh Selvam, Ankita Bansal, Harpreet Singh, Deba Prasad Dhibhar, Vikas Suri, Ashish Bhalla","doi":"10.1177/00494755241287261","DOIUrl":"10.1177/00494755241287261","url":null,"abstract":"<p><p>We present the case of a young female with fever, rash, and joint pain without any other history of connective tissue disorder, who was found on evaluation to have neutrophilic leucocytosis, elevated inflammatory markers and lymphadenopathy with hepatosplenomegaly. After extensive workup, the possibility of adult onset Still's disease was suggested by Yamaguchi criteria. She was started on naproxen, but later on developed drug-induced liver injury. She already had central serous retinopathy due to steroid use, and it was difficult to treat the adult-onset Stills disease due to the liver injury in view of contraindication to use of anti-inflammatory drugs but her illness was monocyclic and did not require further immunosuppression.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"62-64"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal neonatal varicella infection despite intravenous immunoglobulin at birth. 新生儿出生后尽管注射了静脉免疫球蛋白，但仍感染了致命的新生儿水痘。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-10-07 DOI: 10.1177/00494755241287809
Mohammad Yusuf Ali Mazhari, Anukriti Agnihotry, Mayank Priyadarshi, Suman Chaurasia, Poonam Singh, Sriparna Basu
{"title":"Fatal neonatal varicella infection despite intravenous immunoglobulin at birth.","authors":"Mohammad Yusuf Ali Mazhari, Anukriti Agnihotry, Mayank Priyadarshi, Suman Chaurasia, Poonam Singh, Sriparna Basu","doi":"10.1177/00494755241287809","DOIUrl":"10.1177/00494755241287809","url":null,"abstract":"<p><p>There is a high risk of severe varicella infection in the neonate when the mother develops a rash around the time of delivery. Current guidelines recommend separation of mother-baby dyad and passive immunization to prevent severe infection in such cases. We report a case of severe varicella in a neonate whose mother developed primary varicella infection two days prior to delivery. The neonate had a fatal outcome despite physical separation from mother and passive immunization in the immediate postnatal period.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"67-68"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Academic surgery: A road less travelled. 学术外科：一条很少有人走过的路。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-12-05 DOI: 10.1177/00494755241301425
Dhananjaya Sharma, Pawan Agarwal, Michael Cotton
{"title":"Academic surgery: A road less travelled.","authors":"Dhananjaya Sharma, Pawan Agarwal, Michael Cotton","doi":"10.1177/00494755241301425","DOIUrl":"10.1177/00494755241301425","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"1-3"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyoscyamus niger poisoning in Sudan: A case report. 苏丹的黑百部中毒：病例报告。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-10-18 DOI: 10.1177/00494755241289456
Ibrahim Nagmeldin Hassan
{"title":"<i>Hyoscyamus niger</i> poisoning in Sudan: A case report.","authors":"Ibrahim Nagmeldin Hassan","doi":"10.1177/00494755241289456","DOIUrl":"10.1177/00494755241289456","url":null,"abstract":"<p><p>Hyoscyamus niger, commonly known as henbane, contains potent alkaloids that can cause anticholinergic toxicity when ingested. This case report describes a 35-year-old male gardener who presented with confusion, hallucinations, dry mouth, and dilated pupils after consuming parts of the plant. The patient was treated with rehydration, activated charcoal, and physostigmine, leading to rapid clinical improvement. This case highlights the importance of recognizing plant-based poisonings and the efficacy of physostigmine in managing anticholinergic syndrome. Public awareness and education on the dangers of unfamiliar plants are essential to prevent accidental ingestions.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"69-70"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal analgesic prescription practices in central India: A cross-sectional survey. 印度中部的新生儿镇痛处方实践：一项横断面调查。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-10-08 DOI: 10.1177/00494755241288292
Vrinda Agarwal, Jaya Upadhyay, Nency Sahu, Rashmi Parihar, Pawan Agarwal, Dhananjaya Sharma
{"title":"Neonatal analgesic prescription practices in central India: A cross-sectional survey.","authors":"Vrinda Agarwal, Jaya Upadhyay, Nency Sahu, Rashmi Parihar, Pawan Agarwal, Dhananjaya Sharma","doi":"10.1177/00494755241288292","DOIUrl":"10.1177/00494755241288292","url":null,"abstract":"<p><p>This descriptive survey assessed knowledge, attitude and practice regarding analgesic prescription practices in neonates. A web-based questionnaire was developed and circulated to 150 physicians working in public and private neonatal intensive care units, of whom 87% were aware of neonatal pain perception; however, only 57.3% had any definite pain management policy. Some 66% were aware of a pain assessment tool in neonates, yet none had used it, though 80% used analgesics in their neonatal intensive care unit but only 44.3% were satisfied with the subsequent pain management. The most commonly used agents were midazolam and fentanyl. A total of 55% thought that opioid analgesia should not be used in neonates and morphine was used by only 5%; however, there seemed a general acceptance of opioid use since 86% used fentanyl as an analgesic. Non-pharmacological methods were used by 81%. Pain treatment in neonatal intensive care units is thus suboptimal and requires more attention.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"11-14"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical predictors of warfarin-associated bleeding: A case-control study. 华法林相关出血的临床预测因素：病例对照研究
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-10-10 DOI: 10.1177/00494755241287952
Shahanaze Javath Hussain, Surendran Deepanjali, Hemachandren Munuswamy
{"title":"Clinical predictors of warfarin-associated bleeding: A case-control study.","authors":"Shahanaze Javath Hussain, Surendran Deepanjali, Hemachandren Munuswamy","doi":"10.1177/00494755241287952","DOIUrl":"10.1177/00494755241287952","url":null,"abstract":"<p><p>Despite the advent of directly acting oral anticoagulants, warfarin is still widely used in resource-poor settings. Bleeding as a result of warfarin overdosage is common and risk factors seem to vary between patient populations. Predictors of bleeding in patients using warfarin were studied using a case-control design. We calculated the Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly, Drugs/Alcohol (HAS-BLED) score (a bleeding risk prediction tool). Cases chosen were adults prescribed warfarin presenting with bleeding and controls were likewise taking warfarin but had no bleeding in the previous six months. The most common indication for warfarin use was venous thromboembolism. Recent decrease in food intake was strongly associated with bleeding. Older age, higher warfarin doses, recent illness in the past fortnight and prior bleeding were also independent predictors. A higher HAS-BLED score was not predictive independently. Closer monitoring of international normalised ratio is therefore advisable during acute illnesses and in those with decreased food intake.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"5-10"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Less invasive surfactant administration with specially designed semirigid catheter: Experience from a tertiary level neonatal unit of a lower middle-income country. 使用特殊设计的半硬质导管进行微创表面活性物质给药：一个中低收入国家三级新生儿科的经验。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-10-14 DOI: 10.1177/00494755241288931
Sourabh Kumar, Pankaj Chaudhary, Mayank Priyadarshi, Suman Chaurasia, Poonam Singh, Sriparna Basu
{"title":"Less invasive surfactant administration with specially designed semirigid catheter: Experience from a tertiary level neonatal unit of a lower middle-income country.","authors":"Sourabh Kumar, Pankaj Chaudhary, Mayank Priyadarshi, Suman Chaurasia, Poonam Singh, Sriparna Basu","doi":"10.1177/00494755241288931","DOIUrl":"10.1177/00494755241288931","url":null,"abstract":"<p><p>Clinical outcomes of 74 preterm neonates, who received surfactant replacement therapy (SRT), were collected retrospectively, to compare the following modes of administration: (1) less invasive surfactant administration (LISA) via a specially designed semirigid catheter (<i>Surfcath</i>), (2) INtubate-SURfactant-Extubate (INSURE) and (3) through endotracheal tube (ETT), in neonates requiring mechanical ventilation. The primary composite outcome of mortality or bronchopulmonary dysplasia (BPD) at 36 weeks' post-menstrual age was 41% in LISA, 38% in INSURE and 77% in ETT groups (<i>p</i> < 0.01), the difference being mainly due to the high incidence of mortality in the latter. LISA, via a specially designed semirigid catheter, was safe and feasible in preterm neonates.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"15-21"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary tuberculosis and renal amyloidosis: A rare entity in children. 肺结核和肾淀粉样变性：儿童中的罕见病例
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-11-15 DOI: 10.1177/00494755241293181
Vernika Tyagi, Mukta Mantan, Vineeta V Batra
{"title":"Pulmonary tuberculosis and renal amyloidosis: A rare entity in children.","authors":"Vernika Tyagi, Mukta Mantan, Vineeta V Batra","doi":"10.1177/00494755241293181","DOIUrl":"10.1177/00494755241293181","url":null,"abstract":"<p><p>Amyloidosis is a group of disorders with extracellular accumulation of autologous fibrillary insoluble proteins in various tissues and organs such as the kidneys, liver, spleen, heart, and gastrointestinal tract leading to impaired function. Renal amyloidosis is usually considered to be a progressive disease manifesting as nephrotic syndrome and renal insufficiency with tuberculosis being one of the most common causes in adults. However, the occurrence of similar associations is rarely described in children. We report a case of an 11-year old girl who presented with nephrotic syndrome and pulmonary tuberculosis and attained disease remission with successful treatment of tuberculosis.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"71-72"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reactive arthritis in connective tissue diseases; one should be vigilant for joint tuberculosis. 结缔组织病中的反应性关节炎；应警惕关节结核。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-10-29 DOI: 10.1177/00494755241293186
Leng Qian-Ying, Chen Yao
{"title":"Reactive arthritis in connective tissue diseases; one should be vigilant for joint tuberculosis.","authors":"Leng Qian-Ying, Chen Yao","doi":"10.1177/00494755241293186","DOIUrl":"10.1177/00494755241293186","url":null,"abstract":"<p><p>The incidence of tuberculosis (TB) is increasing worldwide. Bone and joint TB are the most common types of extra-pulmonary TB, but can easily be misdiagnosed, since articular TB commonly mimics other joint diseases, including reactive and degenerative arthritis, and articular manifestations associated with systemic autoimmune diseases. Furthermore, patients with systemic auto-immune diseases are often more prone to mycobacterial infection. The diagnosis of joint TB can be made using a combination of the following methods: clinical evaluation, imaging, tuberculin skin test, interferon-gamma release assays, nucleic acid amplification tests, and Gene X-pert MTB/rifampicin assay.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"45-47"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tuberculous calcific constrictive pericarditis in an adult female with a past history of abdominal tuberculosis. 一名既往有腹腔结核病史的成年女性患结核性钙化性收缩性心包炎。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-01-01 Epub Date: 2024-10-03 DOI: 10.1177/00494755241282226
Dhruv Bansal, Moti Lal Negi, Priya Bansal, Aakash Pandey
{"title":"Tuberculous calcific constrictive pericarditis in an adult female with a past history of abdominal tuberculosis.","authors":"Dhruv Bansal, Moti Lal Negi, Priya Bansal, Aakash Pandey","doi":"10.1177/00494755241282226","DOIUrl":"10.1177/00494755241282226","url":null,"abstract":"<p><p>Tuberculous pericarditis, one of the rarer extrapulmonary manifestations of tuberculosis, remains a challenge in endemic countries such as India. As the clinical presentation of tuberculous pericarditis is highly variable, the diagnosis is often missed, delayed, or incorrectly diagnosed. Constrictive pericarditis (CP) is one of tuberculous pericarditis's most serious and advanced sequelae. Several invasive and non-invasive diagnostic modalities are crucial to address the challenges of confirming the diagnosis of CP in suspected cases. This study reports the case of an Indian adult female with a past history of previously treated abdominal tuberculosis diagnosed anew with tuberculous calcific constrictive pericarditis.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"57-59"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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