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Hepatitis E virus infection in pregnancy: A narrative review. 妊娠期戊型肝炎病毒感染：综述
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-31 DOI: 10.1177/00494755261437453
Madhu Shishodiya, Shiwani Yadav, Komal Thakur, Manash Debnath, Hindol Maity
{"title":"Hepatitis E virus infection in pregnancy: A narrative review.","authors":"Madhu Shishodiya, Shiwani Yadav, Komal Thakur, Manash Debnath, Hindol Maity","doi":"10.1177/00494755261437453","DOIUrl":"https://doi.org/10.1177/00494755261437453","url":null,"abstract":"<p><p>Hepatitis E virus (HEV) infection is an important cause of acute viral hepatitis worldwide and represents a uniquely severe threat in pregnancy in areas where genotypes 1 and 2 circulate. In low-resource tropical settings, and particularly in the World Health Organization (WHO) Southeast Asia region, HEV infection during pregnancy is associated with disproportionately high maternal case fatality, frequent progression to acute liver failure, and devastating foetal and perinatal outcomes. This narrative review synthesises contemporary evidence on epidemiology, pathogenesis, clinical presentation, maternal and foetal outcomes, management challenges, and prevention strategies with a focus on tropical practice. Critical gaps in diagnostic capacity, access to critical care, and vaccine deployment are highlighted, and practical recommendations are offered to clinicians and health systems working in endemic settings. Strengthened surveillance, outbreak preparedness, inclusion of pregnant women in vaccine policy deliberations, and improved antenatal counselling are essential to reduce preventable deaths from HEV in pregnancy.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261437453"},"PeriodicalIF":0.6,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monkey tapeworm infection in a Sri Lankan child. 斯里兰卡儿童猴绦虫感染。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-31 DOI: 10.1177/00494755261437455
Thusharah Thanthirige, Rohinie Premaratne, Samantha Chandrarathna, Rohitha Muthugala
{"title":"Monkey tapeworm infection in a Sri Lankan child.","authors":"Thusharah Thanthirige, Rohinie Premaratne, Samantha Chandrarathna, Rohitha Muthugala","doi":"10.1177/00494755261437455","DOIUrl":"https://doi.org/10.1177/00494755261437455","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261437455"},"PeriodicalIF":0.6,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical profile and predictors of mortality among people living with HIV/AIDS with Mycobacterium tuberculosis detected in blood or bone marrow at a tertiary hospital in Northeast Brazil. 巴西东北部一家三级医院血液或骨髓中检测到结核分枝杆菌的艾滋病毒/艾滋病患者的临床概况和死亡率预测因素。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-30 DOI: 10.1177/00494755261435265
Adriano Monteiro da Silva, Pedro Italo Oliveira Gomes, Ivna Felice Silva Matos, Ednaldo Pereira Lima Sobrinho, Luís Arthur Brasil Gadelha Farias, Lauro Vieira Perdigão Neto
{"title":"Clinical profile and predictors of mortality among people living with HIV/AIDS with <i>Mycobacterium tuberculosis</i> detected in blood or bone marrow at a tertiary hospital in Northeast Brazil.","authors":"Adriano Monteiro da Silva, Pedro Italo Oliveira Gomes, Ivna Felice Silva Matos, Ednaldo Pereira Lima Sobrinho, Luís Arthur Brasil Gadelha Farias, Lauro Vieira Perdigão Neto","doi":"10.1177/00494755261435265","DOIUrl":"https://doi.org/10.1177/00494755261435265","url":null,"abstract":"<p><p><i>Mycobacterium tuberculosis</i> bacteraemia is a severe manifestation of tuberculosis in people living with human immunodeficiency virus acquired immune deficiency syndrome, associated with high mortality. We found patients with fatal outcomes had significantly lower lymphocyte, platelet, and CD4+ T-lymphocyte counts, and higher urea levels (<i>p</i> < 0.05). CD4+ T-lymphocyte count <32 cells/mm<sup>3</sup> was independently associated with mortality (<i>p</i> = 0.005). The oral rifampicin, isoniazid, pyrazinamide, and ethambutol regime was more frequent among survivors. Social vulnerability factors were common but not independently associated with mortality.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261435265"},"PeriodicalIF":0.6,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zika virus infection preceding Guillain-Barré syndrome: Two cases from Southern India. 吉兰-巴罗综合征前寨卡病毒感染：印度南部2例。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-29 DOI: 10.1177/00494755261437243
Amrita Pattanaik, Nidhi Ashtaputre, Reeta S Mani, Chiranjay Mukhopadhyay, Aparna R Pai
{"title":"Zika virus infection preceding Guillain-Barré syndrome: Two cases from Southern India.","authors":"Amrita Pattanaik, Nidhi Ashtaputre, Reeta S Mani, Chiranjay Mukhopadhyay, Aparna R Pai","doi":"10.1177/00494755261437243","DOIUrl":"https://doi.org/10.1177/00494755261437243","url":null,"abstract":"<p><p>Guillain-Barré syndrome (GBS) is a leading cause of acute flaccid paralysis and has been associated with several arboviral infections. It is an acute immune-mediated polyradiculo-neuropathy characterised by rapidly progressive limb weakness, areflexia, and variable cranial nerve involvement. Antecedent infections are reported in the majority of patients, most commonly gastro-intestinal or respiratory. In recent years, arboviruses such as Dengue, Chikungunya, and Zika have emerged as important infectious triggers of GBS, particularly in tropical regions. Zika virus infection is often asymptomatic or presents with non-specific febrile illness, making it likely to be under-diagnosed in endemic settings.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261437243"},"PeriodicalIF":0.6,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An "ABCDE" Approach to Poorly Controlled Asthma for Clinicians in Low-Middle Income Countries. 中低收入国家临床医生控制不良哮喘的“ABCDE”方法
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-27 DOI: 10.1177/00494755261436081
Isaac Ks Ng, Justin Jang, Wilson Gw Goh, Christopher Thong
{"title":"An \"ABCDE\" Approach to Poorly Controlled Asthma for Clinicians in Low-Middle Income Countries.","authors":"Isaac Ks Ng, Justin Jang, Wilson Gw Goh, Christopher Thong","doi":"10.1177/00494755261436081","DOIUrl":"https://doi.org/10.1177/00494755261436081","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261436081"},"PeriodicalIF":0.6,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ovophis tonkinensis envenoming presenting with severe isolated thrombocytopenia and local necrosis: A case report. 以严重孤立性血小板减少和局部坏死为主要表现的东京卵母鼠发病1例。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-26 DOI: 10.1177/00494755261435153
Nguyen Dang Duc, Lam Nguyen Hong Anh, Lam Nguyen Hong Khanh, Nguyen Dang Bach
{"title":"<i>Ovophis tonkinensis</i> envenoming presenting with severe isolated thrombocytopenia and local necrosis: A case report.","authors":"Nguyen Dang Duc, Lam Nguyen Hong Anh, Lam Nguyen Hong Khanh, Nguyen Dang Bach","doi":"10.1177/00494755261435153","DOIUrl":"https://doi.org/10.1177/00494755261435153","url":null,"abstract":"<p><p>Pit viper envenoming commonly causes venom-induced consumption coagulopathy with hypofibrinogenaemia. However, isolated thrombocytopenia without fibrinogen depletion is less recognised and may alter transfusion strategy. We report a confirmed <i>Ovophis tonkinensis</i> bite from northern Vietnam presenting with severe isolated thrombocytopenia and local necrosis. The case highlights the importance of serial platelet monitoring, awareness of fibrinogen availability and appropriate timing of antivenom and platelet support in resource-limited tropical settings.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261435153"},"PeriodicalIF":0.6,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147516217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatic histoplasmosis presenting as portal hypertension in an immunocompetent elderly male: A multidisciplinary case report. 肝组织浆菌病表现为门静脉高压症的免疫能力老年男性：多学科病例报告。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-23 DOI: 10.1177/00494755261435267
Divya Jyoti, Priti Singh, L H Ghotekar
{"title":"Hepatic histoplasmosis presenting as portal hypertension in an immunocompetent elderly male: A multidisciplinary case report.","authors":"Divya Jyoti, Priti Singh, L H Ghotekar","doi":"10.1177/00494755261435267","DOIUrl":"https://doi.org/10.1177/00494755261435267","url":null,"abstract":"<p><p>Histoplasmosis, caused by <i>Histoplasma capsulatum</i>, is a dimorphic fungus typically endemic to parts of the Americas, Africa, and Asia. Inhalational exposure leads primarily to pulmonary infection, and extrapulmonary or isolated hepatic presentations are rare, particularly in immuno-competent individuals. We present an unusual case of hepatic histoplasmosis with no evident lung involvement, highlighting a diagnostic challenge and a rewarding pathologic discovery.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261435267"},"PeriodicalIF":0.6,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe thrombocytopenia without major haemorrhage in dengue in a patient on dual antiplatelet therapy; a real world clinical experience. 接受双重抗血小板治疗的登革热患者无大出血的严重血小板减少真实世界的临床经验。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-23 DOI: 10.1177/00494755261433316
Anne Thushara Matthias, Viduni Suraweera
{"title":"Severe thrombocytopenia without major haemorrhage in dengue in a patient on dual antiplatelet therapy; a real world clinical experience.","authors":"Anne Thushara Matthias, Viduni Suraweera","doi":"10.1177/00494755261433316","DOIUrl":"https://doi.org/10.1177/00494755261433316","url":null,"abstract":"<p><p>Dengue is endemic in tropical regions and bleeding, ranging from minor to life-threatening, is a dreaded complication. With the increasing incidence of atherosclerotic cardiovascular disease in low- to middle-income countries where Dengue is prevalent, whether to stop or continue antiplatelet agents in patients with thrombocytopenia is a clinical conundrum.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261433316"},"PeriodicalIF":0.6,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complicated versus uncomplicated amoebic liver abscess in adult: A prospective analysis of clinical presentation, disease course, and outcomes. 成人阿米巴肝脓肿的复杂性与非复杂性：临床表现、病程和结局的前瞻性分析。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-23 DOI: 10.1177/00494755261432412
Jinit R Soni, Ramesh Kumar, Sudhir Kumar, Rajeev N Priyadarshi, Utpal Anand, Rishabh Patel
{"title":"Complicated versus uncomplicated amoebic liver abscess in adult: A prospective analysis of clinical presentation, disease course, and outcomes.","authors":"Jinit R Soni, Ramesh Kumar, Sudhir Kumar, Rajeev N Priyadarshi, Utpal Anand, Rishabh Patel","doi":"10.1177/00494755261432412","DOIUrl":"https://doi.org/10.1177/00494755261432412","url":null,"abstract":"<p><p>Amoebic liver abscess (ALA) is often associated with significant complications. Contemporary prospective data comprehensively characterizing complicated and uncomplicated ALA are limited. This prospective cohort study followed 150 patients with ALA and found that 60.7% experienced at least one complication. The significant complications were peritoneal rupture, pleural rupture, venous thrombosis, biliary fistula, secondary bacterial infection, and organ dysfunction. Patients with complicated ALA had larger abscesses, higher inflammatory markers, and greater liver dysfunction than those without complications. The types of complications were influenced by the location of the ALA. Additionally, subcapsular abscesses and lower baseline HDL-cholesterol levels were independently linked to complicated cases of ALA. Although complications were common, both groups showed favourable outcomes. Mortality was 2%, occurring only in the complicated group. At three months, both groups had comparable rates of symptom resolution, cavity disappearance, and relapse.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261432412"},"PeriodicalIF":0.6,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abdominal actinomycosis as a mimic of intestinal cancer: Case report. 腹腔放线菌病与肠癌的相似：1例报告。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-03-19 DOI: 10.1177/00494755261428913
Lady Viviana Acosta Castillo, Carlos Daniel Ortega Uribe, Paula Andrea Salas Espinosa, Martin Ocampo Posada, Andres David Sastre Martinez, Hernán Mauricio Ocampo Aguirre
{"title":"Abdominal actinomycosis as a mimic of intestinal cancer: Case report.","authors":"Lady Viviana Acosta Castillo, Carlos Daniel Ortega Uribe, Paula Andrea Salas Espinosa, Martin Ocampo Posada, Andres David Sastre Martinez, Hernán Mauricio Ocampo Aguirre","doi":"10.1177/00494755261428913","DOIUrl":"https://doi.org/10.1177/00494755261428913","url":null,"abstract":"<p><p>Actinomycosis is an uncommon, chronic bacterial infection caused by <i>Actinomyces spp</i>, whose abdominal form often mimics malignant disease and poses a diagnostic challenge.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261428913"},"PeriodicalIF":0.6,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147488169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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