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Before Guillain-Barré syndrome is attributed to a Zika infection, the presence of flavivirus RNA must be confirmed by PCR. 在将吉兰-巴罗综合征归因于寨卡病毒感染之前，必须通过聚合酶链反应确认黄病毒RNA的存在。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-16 DOI: 10.1177/00494755261499943
Fulvio Scorza, Josef Finsterer
{"title":"Before Guillain-Barré syndrome is attributed to a Zika infection, the presence of flavivirus RNA must be confirmed by PCR.","authors":"Fulvio Scorza, Josef Finsterer","doi":"10.1177/00494755261499943","DOIUrl":"https://doi.org/10.1177/00494755261499943","url":null,"abstract":"<p><p>The Zika virus, an RNA arbovirus, is known to trigger Guillain-Barré syndrome (GBS). However, to establish that the Zika virus is indeed the causative agent, its presence must be confirmed - preferably via direct PCR. Detection of anti-Zika IgM antibodies should not be used for this purpose, as they can persist. Confirming Zika as the trigger for GBS also requires ruling out all other potential causes of the syndrome. Furthermore, all comorbidities and concomitant medications must be documented and included in the analysis. Finally, it is essential to refer GBS patients, regardless of the underlying cause, to a specialized department as soon as typical clinical symptoms appear.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261499943"},"PeriodicalIF":0.6,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149197228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimising empirical therapy for actinomycetoma in diagnostic-limited settings: Prioritising Amikacin and Linezolid via an Integrated Evidence-Concordance Framework. 在诊断受限的情况下优化放线菌瘤的经验疗法：通过综合证据-一致性框架优先考虑阿米卡星和利奈唑胺。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-15 DOI: 10.1177/00494755261499053
Mohamed E Hamid, Mohamed Saadeldein
{"title":"Optimising empirical therapy for actinomycetoma in diagnostic-limited settings: Prioritising Amikacin and Linezolid via an Integrated Evidence-Concordance Framework.","authors":"Mohamed E Hamid, Mohamed Saadeldein","doi":"10.1177/00494755261499053","DOIUrl":"https://doi.org/10.1177/00494755261499053","url":null,"abstract":"<p><p>Actinomycetoma is a chronic, destructive infection of the skin and subcutaneous tissues that is often treated empirically in endemic settings because species identification and antimicrobial susceptibility testing are unavailable or delayed. We developed an Evidence-Concordance Framework (ECF) integrating published clinical outcomes, phenotypic susceptibility data and CARD-RGI resistome predictions for major <i>Nocardia</i>, <i>Actinomadura</i> and <i>Streptomyces</i> pathogens. Amikacin and linezolid showed the strongest concordance across the three evidence domains. Trimethoprim-sulfamethoxazole (TMP-SMX) remained the therapeutic backbone despite variable in vitro susceptibility, particularly among <i>Streptomyces</i>. Genomic resistance determinants often showed limited agreement with phenotypic or clinical outcomes. The ECF therefore supports TMP-SMX-based therapy, with amikacin and linezolid as strongly supported adjunctive or alternative agents. Genomic prediction should complement, not replace, clinical judgement, species identification and phenotypic susceptibility testing.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261499053"},"PeriodicalIF":0.6,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149197186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute hepatitis E presenting with fulminant myocarditis and cardiogenic shock: A case report from Nepal. 急性戊型肝炎并发暴发性心肌炎和心源性休克：尼泊尔一例报告。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-15 DOI: 10.1177/00494755261499050
Ajay Bhatta, Astha Wagle, Birendra Bhandari, Sarita Kunwar, Sudip Lamsal
{"title":"Acute hepatitis E presenting with fulminant myocarditis and cardiogenic shock: A case report from Nepal.","authors":"Ajay Bhatta, Astha Wagle, Birendra Bhandari, Sarita Kunwar, Sudip Lamsal","doi":"10.1177/00494755261499050","DOIUrl":"https://doi.org/10.1177/00494755261499050","url":null,"abstract":"<p><p>Hepatitis E virus infection is endemic in Nepal and commonly presents as an acute self-limiting hepatitis. Cardiac involvement is extremely rare and may be life-threatening. We report a case of a young female who presented with fever, jaundice, progressive dyspnea and hypotension. Laboratory assessment confirmed acute hepatitis E infection. Chest radiography revealed cardiomegaly with bilateral pulmonary infiltrates. Transthoracic echocardiography demonstrated left ventricular dysfunction. Other infectious causes of myocarditis were excluded. The patient improved with inotropic support, heart failure treatment and other supportive management, with complete clinical recovery on follow-up. This case highlights the importance of early cardiac evaluation in patients with acute hepatitis E with features of heart failure.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261499050"},"PeriodicalIF":0.6,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149197225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The 'lived-in experience' of global health: The grassroots wisdom we risk losing. 全球卫生的“亲身体验”：我们可能失去的草根智慧
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-14 DOI: 10.1177/00494755261499021
Dhananjaya Sharma
{"title":"The 'lived-in experience' of global health: The grassroots wisdom we risk losing.","authors":"Dhananjaya Sharma","doi":"10.1177/00494755261499021","DOIUrl":"https://doi.org/10.1177/00494755261499021","url":null,"abstract":"<p><p>Global Health has accumulated unprecedented knowledge through frameworks, indicators, guidelines, datasets and increasingly powerful digital tools. Yet one valuable resource remains remarkably underused: the lived-in experience of people who have spent decades delivering grassroots health care. This experience is more than accumulated information; it is tacit wisdom shaped by repeated encounters with patients, communities, health systems, scarcity, failure, adaptation and unintended consequences. Such wisdom reveals what actually works, what fails, why programmes succeed or falter at the last mile, and where globally developed guidance requires local adaptation. As experienced health workers retire, this unwritten knowledge risks disappearing. Listening to them is therefore both a practical necessity and a form of respect.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261499021"},"PeriodicalIF":0.6,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The surgical sustainability phenotype (SSP): A proposed framework for environmental phenotyping in surgery. 手术可持续性表型（SSP）：手术环境表型的建议框架。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-14 DOI: 10.1177/00494755261492935
Dhananjaya Sharma, Michael Cotton
{"title":"The surgical sustainability phenotype (SSP): A proposed framework for environmental phenotyping in surgery.","authors":"Dhananjaya Sharma, Michael Cotton","doi":"10.1177/00494755261492935","DOIUrl":"https://doi.org/10.1177/00494755261492935","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261492935"},"PeriodicalIF":0.6,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrating artificial intelligence in research: The supremacy of idea and the I.D.E.A. Framework. 将人工智能整合到研究中：思想的至高无上性和I.D.E.A.框架。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-14 DOI: 10.1177/00494755261499546
Pankaj Garg, Vipul Yagnik
{"title":"Integrating artificial intelligence in research: The supremacy of idea and the I.D.E.A. Framework.","authors":"Pankaj Garg, Vipul Yagnik","doi":"10.1177/00494755261499546","DOIUrl":"https://doi.org/10.1177/00494755261499546","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261499546"},"PeriodicalIF":0.6,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal pulmonary melioidosis presenting as thoracic empyema and septic shock in an arid region of India. 致命的肺类鼻疽症表现为胸脓肿和败血性休克在印度干旱地区。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-09 DOI: 10.1177/00494755261488196
Anamika S Parvati, Meenakshi Pareek, Kumar S Abhishek, Yogendra S Rathore, Taruna Yadav, Vibhor Tak
{"title":"Fatal pulmonary melioidosis presenting as thoracic empyema and septic shock in an arid region of India.","authors":"Anamika S Parvati, Meenakshi Pareek, Kumar S Abhishek, Yogendra S Rathore, Taruna Yadav, Vibhor Tak","doi":"10.1177/00494755261488196","DOIUrl":"https://doi.org/10.1177/00494755261488196","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261488196"},"PeriodicalIF":0.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of artificial intelligence chatbots for generating management plans in paediatric intensive care and pulmonology cases: A comparative study. 评估人工智能聊天机器人在儿科重症监护和肺科病例中生成管理计划：一项比较研究。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-09 DOI: 10.1177/00494755261493668
Lalit Takia, Poonam Godhwal, Varsha Mishra, Deepsekhar Das, Atindra Narayan
{"title":"Evaluation of artificial intelligence chatbots for generating management plans in paediatric intensive care and pulmonology cases: A comparative study.","authors":"Lalit Takia, Poonam Godhwal, Varsha Mishra, Deepsekhar Das, Atindra Narayan","doi":"10.1177/00494755261493668","DOIUrl":"https://doi.org/10.1177/00494755261493668","url":null,"abstract":"<p><p>Artificial intelligence (AI) chatbots are increasingly explored as clinical decision support tools, but their accuracy and applicability remain insufficiently evaluated. We therefore evaluated and compared the accuracy, completeness, readability, and real-world applicability of four AI chatbots in generating treatment plans for Paediatric Pulmonology Intensive care and Emergency cases.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261493668"},"PeriodicalIF":0.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute mesenteric ischaemia after prolonged entrapment in an earthquake survivor with crush syndrome. 挤压综合征地震幸存者长时间夹持后急性肠系膜缺血。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-08 DOI: 10.1177/00494755261495783
Adem Şafak
{"title":"Acute mesenteric ischaemia after prolonged entrapment in an earthquake survivor with crush syndrome.","authors":"Adem Şafak","doi":"10.1177/00494755261495783","DOIUrl":"https://doi.org/10.1177/00494755261495783","url":null,"abstract":"<p><p>Acute mesenteric ischaemia is a life-threatening emergency that is easily overlooked when several body systems are injured at once. We describe a 51-year old woman extricated 50 h after the earthquake of 6 February 2023 in Kahramanmaraş, Turkey, who presented with crush syndrome, oliguric acute kidney injury and peritoneal signs; her abdominal pain had begun while she was still trapped. Prolonged immobility and hypovolaemia during entrapment may produce <i>in situ</i> mesenteric thrombosis, and the abdomen of a crush victim warrants repeated examination.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261495783"},"PeriodicalIF":0.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A failing arsenal: Preserving newborn health amid pan-drug resistance. 失败的武器库：在普遍耐药性中保护新生儿健康。
IF 0.6 4区 医学
Tropical Doctor Pub Date : 2026-10-08 DOI: 10.1177/00494755261495792
Shahid Akhtar Siddiqui
{"title":"A failing arsenal: Preserving newborn health amid pan-drug resistance.","authors":"Shahid Akhtar Siddiqui","doi":"10.1177/00494755261495792","DOIUrl":"https://doi.org/10.1177/00494755261495792","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755261495792"},"PeriodicalIF":0.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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