{"title":"Complete renal response of IgA vasculitis with steroid and mycophenolate mofetil in an adult HIV patient.","authors":"Naman Mahesh Pathak, Kritika Pant, Jyoti Aggarwal, Joydeep Samanta, Satyaki Ganguly, Vinay Rathore","doi":"10.1177/00494755241282365","DOIUrl":"https://doi.org/10.1177/00494755241282365","url":null,"abstract":"<p><p>IgA vasculitis in adult HIV patients is rare and not well understood. Data on treatment of IgA vasculitis associated with HIV is sparse and limited to case reports. Highly active antiretroviral therapy (HAART) is the mainstay therapy for inducing remission. We report a case of a 41-year old HIV patient who presented with palpable purpura, melaena and oedema and was diagnosed with IgA vasculitis with severe renal (crescentic glomerulonephritis), gastrointestinal and skin involvement. He was treated with immunosuppressive drugs and HAART which led to remission of disease. This case is unusual due to the presence of crescentic glomerulopathy and the requirement of immunosuppression for remission induction.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical predictors of warfarin-associated bleeding: A case-control study.","authors":"Shahanaze Javath Hussain, Surendran Deepanjali, Hemachandren Munuswamy","doi":"10.1177/00494755241287952","DOIUrl":"https://doi.org/10.1177/00494755241287952","url":null,"abstract":"<p><p>Despite the advent of directly acting oral anticoagulants, warfarin is still widely used in resource-poor settings. Bleeding as a result of warfarin overdosage is common and risk factors seem to vary between patient populations. Predictors of bleeding in patients using warfarin were studied using a case-control design. We calculated the Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly, Drugs/Alcohol (HAS-BLED) score (a bleeding risk prediction tool). Cases chosen were adults prescribed warfarin presenting with bleeding and controls were likewise taking warfarin but had no bleeding in the previous six months. The most common indication for warfarin use was venous thromboembolism. Recent decrease in food intake was strongly associated with bleeding. Older age, higher warfarin doses, recent illness in the past fortnight and prior bleeding were also independent predictors. A higher HAS-BLED score was not predictive independently. Closer monitoring of international normalised ratio is therefore advisable during acute illnesses and in those with decreased food intake.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neonatal analgesic prescription practices in central India: A cross-sectional survey.","authors":"Vrinda Agarwal, Jaya Upadhyay, Nency Sahu, Rashmi Parihar, Pawan Agarwal, Dhananjaya Sharma","doi":"10.1177/00494755241288292","DOIUrl":"https://doi.org/10.1177/00494755241288292","url":null,"abstract":"<p><p>This descriptive survey assessed knowledge, attitude and practice regarding analgesic prescription practices in neonates. A web-based questionnaire was developed and circulated to 150 physicians working in public and private neonatal intensive care units, of whom 87% were aware of neonatal pain perception; however, only 57.3% had any definite pain management policy. Some 66% were aware of a pain assessment tool in neonates, yet none had used it, though 80% used analgesics in their neonatal intensive care unit but only 44.3% were satisfied with the subsequent pain management. The most commonly used agents were midazolam and fentanyl. A total of 55% thought that opioid analgesia should not be used in neonates and morphine was used by only 5%; however, there seemed a general acceptance of opioid use since 86% used fentanyl as an analgesic. Non-pharmacological methods were used by 81%. Pain treatment in neonatal intensive care units is thus suboptimal and requires more attention.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tropical DoctorPub Date : 2024-10-07DOI: 10.1177/00494755241287809
Mohammad Yusuf Ali Mazhari, Anukriti Agnihotry, Mayank Priyadarshi, Suman Chaurasia, Poonam Singh, Sriparna Basu
{"title":"Fatal neonatal varicella infection despite intravenous immunoglobulin at birth.","authors":"Mohammad Yusuf Ali Mazhari, Anukriti Agnihotry, Mayank Priyadarshi, Suman Chaurasia, Poonam Singh, Sriparna Basu","doi":"10.1177/00494755241287809","DOIUrl":"https://doi.org/10.1177/00494755241287809","url":null,"abstract":"<p><p>There is a high risk of severe varicella infection in the neonate when the mother develops a rash around the time of delivery. Current guidelines recommend separation of mother-baby dyad and passive immunization to prevent severe infection in such cases. We report a case of severe varicella in a neonate whose mother developed primary varicella infection two days prior to delivery. The neonate had a fatal outcome despite physical separation from mother and passive immunization in the immediate postnatal period.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tuberculous calcific constrictive pericarditis in an adult female with a past history of abdominal tuberculosis.","authors":"Dhruv Bansal, Moti Lal Negi, Priya Bansal, Aakash Pandey","doi":"10.1177/00494755241282226","DOIUrl":"https://doi.org/10.1177/00494755241282226","url":null,"abstract":"<p><p>Tuberculous pericarditis, one of the rarer extrapulmonary manifestations of tuberculosis, remains a challenge in endemic countries such as India. As the clinical presentation of tuberculous pericarditis is highly variable, the diagnosis is often missed, delayed, or incorrectly diagnosed. Constrictive pericarditis (CP) is one of tuberculous pericarditis's most serious and advanced sequelae. Several invasive and non-invasive diagnostic modalities are crucial to address the challenges of confirming the diagnosis of CP in suspected cases. This study reports the case of an Indian adult female with a past history of previously treated abdominal tuberculosis diagnosed anew with tuberculous calcific constrictive pericarditis.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enteral feeding in neonates ≥34 weeks of gestation with moderate to severe birth asphyxia: A retrospective observational study.","authors":"Sandeep Jhajra, Debasish Nanda, Jagjit Singh Dalal","doi":"10.1177/00494755241255162","DOIUrl":"10.1177/00494755241255162","url":null,"abstract":"<p><p>There are no standard guidelines regarding time for initiation of feeds in moderate to severely asphyxiated neonates and data regarding the same in neonates are scanty. Case sheets of all neonates born ≥34 weeks of gestation who satisfied the definition were analysed. The early feeding group was defined as those in whomh feeds were started <24 h and the late feeding group as those started ≥24 h of life. The primary outcome of the study was time to achieve full enteral feeds. A total of 184 neonates were enrolled. Mean time to reach full enteral feeding was 53.7 ± 24.8 h in the early feeding group as compared to 95.0 ± 81.1 h in late enteral feeding group, with a mean difference of 41.3 (25.7-56.8) h. The incidence of adverse secondary outcomes was higher in the late feeding group.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141066335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tropical DoctorPub Date : 2024-10-01Epub Date: 2024-07-23DOI: 10.1177/00494755241260477
Yashita Gupta, Vats Mehta
{"title":"Granulomatous mycosis fungoides: A difficult diagnosis!","authors":"Yashita Gupta, Vats Mehta","doi":"10.1177/00494755241260477","DOIUrl":"10.1177/00494755241260477","url":null,"abstract":"<p><p>Mycosis fungoides (MF) is the most common type of cutaneous lymphoma. However, granulomatous MF remains a rare subtype. Its incidence is estimated in the literature to be 6.3%. Clinical and pathological diagnosis of this entity is difficult owing to clinical heterogenicity and various histopathological mimics. We report one such case.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Navigating the disappointment of manuscript rejection: An author's dialogue with a reviewer and editor of tropical doctor (TD).","authors":"Kaushik Bhattacharya, Dhananjaya Sharma, Micheal Cotton","doi":"10.1177/00494755241271955","DOIUrl":"10.1177/00494755241271955","url":null,"abstract":"<p><p>With the majority of medical journals having a rejection rate of >80% of submitted manuscripts, it does come as a shock and as grief to the author who great expectations before submission. Though the majority of literature available does mention how to overcome the lacunae in the manuscript before considering resubmission in another journal, none addresses the mental agony and setback the author faces and the way to overcome this setback. Every author should develop immunity and also be adequately mentally prepared to overcome this misery.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Escherichia coli</i> infected scalp abscess with osteomyelitis following a cephalhaematoma in a neonate.","authors":"Achanya Palayullakandi, Pradeep Kumar Gunasekaran, Arushi Gahlot Saini, Apoorva Sood, Anmol Bhatia, Jogender Kumar","doi":"10.1177/00494755241257557","DOIUrl":"10.1177/00494755241257557","url":null,"abstract":"<p><p>We discuss an illustrative case of <i>Escherichia coli</i> infected scalp abscess with osteomyelitis following a cephalhaematoma in a 19-day-old neonate. Cephalhaematoma is a common occurrence in neonates after prolonged labour, instrument-assisted, and traumatic deliveries and resolves spontaneously in the majority of cases. Infection may follow haematogenous dissemination or direct inoculation via a skin breach. Complications such as scalp abscess, sepsis, and osteomyelitis of the skull present with local signs, including increasing size, local erythema and tenderness, and fluctuant swelling.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}