{"title":"一名成年艾滋病患者在使用类固醇和霉酚酸酯治疗 IgA 血管炎后,肾脏出现完全反应。","authors":"Naman Mahesh Pathak, Kritika Pant, Jyoti Aggarwal, Joydeep Samanta, Satyaki Ganguly, Vinay Rathore","doi":"10.1177/00494755241282365","DOIUrl":null,"url":null,"abstract":"<p><p>IgA vasculitis in adult HIV patients is rare and not well understood. Data on treatment of IgA vasculitis associated with HIV is sparse and limited to case reports. Highly active antiretroviral therapy (HAART) is the mainstay therapy for inducing remission. We report a case of a 41-year old HIV patient who presented with palpable purpura, melaena and oedema and was diagnosed with IgA vasculitis with severe renal (crescentic glomerulonephritis), gastrointestinal and skin involvement. He was treated with immunosuppressive drugs and HAART which led to remission of disease. This case is unusual due to the presence of crescentic glomerulopathy and the requirement of immunosuppression for remission induction.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Complete renal response of IgA vasculitis with steroid and mycophenolate mofetil in an adult HIV patient.\",\"authors\":\"Naman Mahesh Pathak, Kritika Pant, Jyoti Aggarwal, Joydeep Samanta, Satyaki Ganguly, Vinay Rathore\",\"doi\":\"10.1177/00494755241282365\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>IgA vasculitis in adult HIV patients is rare and not well understood. Data on treatment of IgA vasculitis associated with HIV is sparse and limited to case reports. Highly active antiretroviral therapy (HAART) is the mainstay therapy for inducing remission. We report a case of a 41-year old HIV patient who presented with palpable purpura, melaena and oedema and was diagnosed with IgA vasculitis with severe renal (crescentic glomerulonephritis), gastrointestinal and skin involvement. He was treated with immunosuppressive drugs and HAART which led to remission of disease. This case is unusual due to the presence of crescentic glomerulopathy and the requirement of immunosuppression for remission induction.</p>\",\"PeriodicalId\":49415,\"journal\":{\"name\":\"Tropical Doctor\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2024-10-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tropical Doctor\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/00494755241282365\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tropical Doctor","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00494755241282365","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
摘要
成人艾滋病病毒感染者的 IgA 血管炎非常罕见,人们对其了解也不多。与艾滋病相关的 IgA 血管炎的治疗数据很少,且仅限于病例报告。高活性抗逆转录病毒疗法(HAART)是诱导病情缓解的主要疗法。我们报告了一例 41 岁的艾滋病患者,他出现可触及的紫癜、黑便和水肿,被诊断为 IgA 血管炎,并伴有严重的肾脏(新月体肾小球肾炎)、胃肠道和皮肤受累。他接受了免疫抑制剂和 HAART 治疗,病情得到缓解。由于新月体性肾小球病变的存在以及需要使用免疫抑制剂来诱导病情缓解,该病例并不常见。
Complete renal response of IgA vasculitis with steroid and mycophenolate mofetil in an adult HIV patient.
IgA vasculitis in adult HIV patients is rare and not well understood. Data on treatment of IgA vasculitis associated with HIV is sparse and limited to case reports. Highly active antiretroviral therapy (HAART) is the mainstay therapy for inducing remission. We report a case of a 41-year old HIV patient who presented with palpable purpura, melaena and oedema and was diagnosed with IgA vasculitis with severe renal (crescentic glomerulonephritis), gastrointestinal and skin involvement. He was treated with immunosuppressive drugs and HAART which led to remission of disease. This case is unusual due to the presence of crescentic glomerulopathy and the requirement of immunosuppression for remission induction.
期刊介绍:
The only journal written by and for health workers in low and middle-income countries, Tropical Doctor provides medical expertise and practical advice on how to apply current medical knowledge to the special circumstances of LMIC countries. This journal provides an ideal forum for sharing experiences and establishing best practice, aiding communication between medical professionals in different environments.