Tropical DoctorPub Date : 2026-10-01Epub Date: 2026-05-30DOI: 10.1177/00494755261456537
Nguyen Dang Duc, Nguyen Trung Nguyen, Lam Nguyen Hong Anh, Lam Nguyen Hong Khanh, Nguyen Dang Bach
{"title":"Methanol concentration predicts severe outcomes in acute methanol poisoning: A Vietnamese cohort.","authors":"Nguyen Dang Duc, Nguyen Trung Nguyen, Lam Nguyen Hong Anh, Lam Nguyen Hong Khanh, Nguyen Dang Bach","doi":"10.1177/00494755261456537","DOIUrl":"10.1177/00494755261456537","url":null,"abstract":"<p><p>Methanol poisoning is a life-threatening condition frequently associated with severe metabolic acidosis, organ failure, and death, particularly in low- and middle-income countries. Early identification of patients at high risk of deterioration is essential for timely intensive management. Unfortunately, patients typically present late after ingestion. Most required intensive care support.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"681-683"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148057876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tropical DoctorPub Date : 2026-10-01Epub Date: 2026-06-02DOI: 10.1177/00494755261456497
Sowmya Gopalan, Datla Pravarshini, Preetam Arthur
{"title":"Methotrexate-related pancytopenia-factors that contribute to its development and outcomes.","authors":"Sowmya Gopalan, Datla Pravarshini, Preetam Arthur","doi":"10.1177/00494755261456497","DOIUrl":"10.1177/00494755261456497","url":null,"abstract":"<p><p>Methotrexate, a commonly used disease-modifying anti-rheumatoid drug, rarely causes bone marrow suppression and pancytopenia. Consequently, we made a retrospective analysis of all patients who were admitted with pancytopenia following low-dose methotrexate intake between 2019 and 2025. Factors that were associated with the development of toxicity, clinical features and outcomes were evaluated. Among those who developed early toxicity, the majority had inadvertently taken daily instead of weekly doses. Renal failure, elderly age and hypoalbuminaemia contributed to delayed toxicity. All were given Folinic acid rescue therapy and 20% needed transfusion support. Two succumbed due to severe neutropenia-related sepsis. Simple patient education on once a week use, dose adjustment and frequent monitoring in the elderly and those with renal failure may help to reduce toxicity.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"701-703"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148145253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tropical DoctorPub Date : 2026-10-01Epub Date: 2026-06-11DOI: 10.1177/00494755261459740
Md Ali Osama, Sanjana Goyal, Nikita Jakhar, Rachna Seth, Asit Ranjan Mridha
{"title":"Fatal haemophagocytic lymphohistiocytosis in a two-month-old infant: An autopsy-based report.","authors":"Md Ali Osama, Sanjana Goyal, Nikita Jakhar, Rachna Seth, Asit Ranjan Mridha","doi":"10.1177/00494755261459740","DOIUrl":"10.1177/00494755261459740","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"782-786"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148220332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rapid turn for the worse: Steroid-responsive pulmonary haemorrhage in leptospirosis.","authors":"Kuljeet Singh, Vinay Venugopal, Kumar Puskar, Bhoomika Kaushik, Praveen Kumar Dubey","doi":"10.1177/00494755261467825","DOIUrl":"10.1177/00494755261467825","url":null,"abstract":"<p><p>A 43-year old man presented with fever and cough and was initially treated for community-acquired pneumonia. Within 24 h, he deteriorated and was admitted with type 1 respiratory failure. A recent history of exposure to waterlogged fields, along with progressive decline in haemoglobin, platelet counts and deranged liver function tests, raised suspicion for leptospirosis, later confirmed by positive IgM serology. With progressive clinical and radiological worsening, severe pulmonary haemorrhagic syndrome was considered. He was managed with oxygen, noninvasive ventilation (NIV), ceftriaxone, doxycycline, cotrimoxazole, and pulse methylprednisolone. He showed significant improvement and was successfully weaned off NIV and oxygen. This case highlights the importance of early recognition and timely initiation of steroid therapy in severe leptospiral pulmonary involvement.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"773-775"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148399886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tropical DoctorPub Date : 2026-10-01Epub Date: 2026-04-20DOI: 10.1177/00494755261442629
Pankaj Garg, Kaushik Bhattacharya, Vipul Yagnik
{"title":"Ultrasound-based scoring to predict long-term healing in anal fistula: A practical alternative or complementary to the MRI-based Garg scoring system?","authors":"Pankaj Garg, Kaushik Bhattacharya, Vipul Yagnik","doi":"10.1177/00494755261442629","DOIUrl":"10.1177/00494755261442629","url":null,"abstract":"<p><p>The published study highlights an important gap in current practice. While MRI remains the gold standard for postoperative evaluation due to its high sensitivity and specificity, its cost and limited availability in some regions may limit routine use. In this context, the development of a Jabalpur Transperineal Ultrasonography-Based Scoring System (J-TPUSS) represents a pragmatic attempt to bridge this disparity. However, several methodological and interpretative concerns merit consideration, which we have discussed in the letter.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"824-825"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tropical DoctorPub Date : 2026-10-01Epub Date: 2026-04-30DOI: 10.1177/00494755261445180
Ram Arvind Viswanathan
{"title":"Rheumatoid-type hand deformities in psoriatic arthritis: An illustrative case.","authors":"Ram Arvind Viswanathan","doi":"10.1177/00494755261445180","DOIUrl":"10.1177/00494755261445180","url":null,"abstract":"<p><p>Psoriatic arthritis (PsA) is a heterogeneous inflammatory arthritis that may mimic rheumatoid arthritis with classical deformities. We report a 65-year old female with established psoriasis presenting with inflammatory hand pain, swan neck and Boutonniere deformities, distal interphalangeal joint tenderness, and hallux varum, along with active psoriatic plaques over the interphalangeal joints. This case underscores the importance of recognising psoriatic arthritis manifesting as classical rheumatoid arthritis hand deformities, given its distinctive treatment implications.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"809-811"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147822850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tropical DoctorPub Date : 2026-10-01Epub Date: 2026-05-30DOI: 10.1177/00494755261455632
Aditya Hemendra Bhatt
{"title":"Antimicrobial stewardship in NICUs of low- and lower-middle-income countries - A narrative review.","authors":"Aditya Hemendra Bhatt","doi":"10.1177/00494755261455632","DOIUrl":"10.1177/00494755261455632","url":null,"abstract":"<p><p>High neonatal sepsis burden and limited diagnostics in low- and lower-middle-income countries (LMICs) drive empiric antibiotic use in neonatal intensive care units (NICUs), increasing antimicrobial resistance. This review examines 19 reports on efforts to kerb this trend. Importantly, reduced use was not associated with increased mortality, sepsis recurrence, necrotising enterocolitis or re-admissions.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"623-625"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148057874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differentiating leptospirosis from Rickettsial diseases and Q fever: A syndrome-based study in Southern Taiwan.","authors":"Shih-Hao Lo, Chung-Hao Huang, Tun-Chieh Chen, Chun-Yu Lin, Po-Liang Lu, Ko Chang","doi":"10.1177/00494755261454021","DOIUrl":"10.1177/00494755261454021","url":null,"abstract":"<p><p>Leptospirosis, Q fever, scrub typhus, and murine typhus are endemic zoonotic diseases in southern Taiwan that often present as acute undifferentiated febrile illness. We retrospectively compared epidemiological, clinical, laboratory, and outcome characteristics of leptospirosis (n = 41) and rickettsial infections, including Q fever, scrub typhus, and murine typhus (QSM; n = 103), in Kaohsiung City from 2013 to 2024. Leptospirosis occurred mainly during rainy and typhoon seasons and was associated with myalgia, gastrointestinal symptoms, jaundice, conjunctival suffusion, hepatic and renal dysfunction, leukocytosis, elevated C-reactive protein, and higher rates of acute kidney injury and shock. QSM occurred year-round, with eschar characteristic of scrub typhus, while prolonged activated partial thromboplastin time and relative bradycardia were more common in QSM. QSM generally showed a milder clinical course, particularly Q fever. Distinct clinical and seasonal patterns may facilitate early differentiation and risk stratification in endemic areas.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"675-680"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148018494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}