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Effect of pantoprazole as an adjunct to standard medical therapy in patients with uncomplicated amoebic liver abscess: A randomised pilot study. 泮托拉唑作为标准药物治疗对无并发症阿米巴肝脓肿患者的辅助作用：一项随机试验研究。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-01-01 DOI: 10.1177/00494755241305213
Rishabh Patel, Ramesh Kumar, Rajeev Nayan Priyadarshi, Sudhir Kumar, Ruchika Narayan, Jinit R Soni
{"title":"Effect of pantoprazole as an adjunct to standard medical therapy in patients with uncomplicated amoebic liver abscess: A randomised pilot study.","authors":"Rishabh Patel, Ramesh Kumar, Rajeev Nayan Priyadarshi, Sudhir Kumar, Ruchika Narayan, Jinit R Soni","doi":"10.1177/00494755241305213","DOIUrl":"10.1177/00494755241305213","url":null,"abstract":"<p><p>Amoebic liver abscess (ALA), a common tropical infection, is caused by <i>Entamoeba histolytica</i> (EH). For decades, the first-line treatment for ALA has been metronidazole which has several drawbacks. The thioredoxin reductase enzyme in EH is essential for its anti-oxidative defence and survival during tissue invasion. Recently, the benzimidazole nucleus of proton pump inhibitors has been found to inhibit it quite effectively. An <i>in vitro</i> study found pantoprazole to be over 100 times more potent than metronidazole. We therefore conducted a randomised open-label pilot study, comparing adjunct pantoprazole with standard medical therapy in patients with uncomplicated ALA. We found this resulted in a shorter hospital stay and faster resolution of fever, abdominal pain, and leucocytosis, compared to standard therapy.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"85-88"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inguinal hernia mesh infections: Chronic challenges, atypical pathogens and lessons in sterilisation. 腹股沟疝网感染：慢性挑战，非典型病原体和消毒教训。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-01-13 DOI: 10.1177/00494755241313152
Debaraj S Purkayastha, Anowar A Mallick, Gautam Das, Satakshi S Purkayastha
{"title":"Inguinal hernia mesh infections: Chronic challenges, atypical pathogens and lessons in sterilisation.","authors":"Debaraj S Purkayastha, Anowar A Mallick, Gautam Das, Satakshi S Purkayastha","doi":"10.1177/00494755241313152","DOIUrl":"10.1177/00494755241313152","url":null,"abstract":"<p><p>Chronic mesh infections after inguinal hernia repair present significant clinical challenges due to biofilm-mediated resistance, involvement of multidrug-resistant and atypical pathogens, and gaps in preventive strategies. Our case series of four patients highlights critical research gaps, including the overlooked role of atypical pathogens such as <i>Mycobacterium tuberculosis</i>, diagnostic challenges in detecting slow-growing or resistant organisms and perioperative sterilisation lapses, especially inconsistent Glutaraldehyde use during late-day operations. Many patients suffered with persistent sinuses and recurrent hernias months after surgery. Microbiological analyses identified <i>Pseudomonas aeruginosa, Klebsiella pneumoniae, Mycobacterium tuberculosis</i> and mixed flora. Complete mesh removal and culture-directed antimicrobial therapy resolved all cases within 8-12 months. Our study underscores the need for robust sterilisation protocols, advanced diagnostic measures and biofilm-resistant biomaterials.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"134-138"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paediatric acral pigmentation related to a beetle contact. 与甲虫接触有关的小儿口角色素沉着。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-01-28 DOI: 10.1177/00494755241313073
Or Kaplan, Gidon Test, Inbal Kestenbom, Oren Tavor
{"title":"Paediatric acral pigmentation related to a beetle contact.","authors":"Or Kaplan, Gidon Test, Inbal Kestenbom, Oren Tavor","doi":"10.1177/00494755241313073","DOIUrl":"10.1177/00494755241313073","url":null,"abstract":"<p><p>We report a case of the appearance of dark pigmented skin on the plantar surface of the foot and toes in a young child, likely caused by the beetle <i>Carabus impressus.</i> Few such documented cases occur in the literature and none reported from our region. Identifying the cause is important to avoid unnecessary investigations and treatment, and to provide reassurance to patients.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"146-147"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating obstetric enigma: Placenta accreta spectrum masquerading as gestational trophoblastic neoplasia. 导航产科之谜：胎盘增生谱伪装成妊娠滋养细胞瘤。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2024-12-26 DOI: 10.1177/00494755241306171
Medha Davile, Avantika Gupta, Anita Yadav, Shuchita Mundle
{"title":"Navigating obstetric enigma: Placenta accreta spectrum masquerading as gestational trophoblastic neoplasia.","authors":"Medha Davile, Avantika Gupta, Anita Yadav, Shuchita Mundle","doi":"10.1177/00494755241306171","DOIUrl":"10.1177/00494755241306171","url":null,"abstract":"<p><p>Placenta accreta spectrum (PAS) represents a complex obstetric condition characterised by the abnormal invasion of anchoring villi and trophoblast into the myometrium. This case report explores two instances where the diagnosis of PAS was overlooked during antenatal care leading to significant complications during conservative management. Both patients presented with heavy menstrual bleeding and raised beta human chorionic gonadotrophin (β-hCG), mimicking gestational trophoblastic disease. The report delves into the clinical presentations, diagnostic challenges, and outcomes of two cases, shedding light on the importance of effective communication and follow-up in the management of PAS.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"139-142"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnetic beads masquerading as a bracelet causing ileal volvulus with multiple ileoileal fistulae in a child: A case report with systematic literature review. 磁珠假手环致儿童回肠扭转并多发回肠瘘1例并系统文献复习。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-03-17 DOI: 10.1177/00494755251328480
Aditya J Baindur, Pradeep K Gupta, Atul Kumar Khare
{"title":"Magnetic beads masquerading as a bracelet causing ileal volvulus with multiple ileoileal fistulae in a child: A case report with systematic literature review.","authors":"Aditya J Baindur, Pradeep K Gupta, Atul Kumar Khare","doi":"10.1177/00494755251328480","DOIUrl":"10.1177/00494755251328480","url":null,"abstract":"<p><p>Multiple magnetic foreign body ingestion can cause serious complications in children. Such events are now more frequently seen. We report such a case and present a systematic review to identify the variety of fistulae thereby caused. Timely diagnosis through radiographic imaging plays a pivotal role in guiding clinical decisions.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"155-160"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shaping global health: The indispensable role of biomedical engineers. 塑造全球健康：生物医学工程师不可或缺的角色。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-04-13 DOI: 10.1177/00494755251333530
Tim Horeman, Dhananjaya Sharma, Michael Cotton
{"title":"Shaping global health: The indispensable role of biomedical engineers.","authors":"Tim Horeman, Dhananjaya Sharma, Michael Cotton","doi":"10.1177/00494755251333530","DOIUrl":"https://doi.org/10.1177/00494755251333530","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":"55 2","pages":"83-84"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated tuberculosis after splenectomy: An uncommon event. 脾切除术后的播散性结核病：不常见的事件。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2024-11-22 DOI: 10.1177/00494755241298875
Deepak Iype Koshy, Joydeep Samanta, Jhasaketan Meher, Vanitha Raj R, Vinay R Pandit, Narendra K Bodhey
{"title":"Disseminated tuberculosis after splenectomy: An uncommon event.","authors":"Deepak Iype Koshy, Joydeep Samanta, Jhasaketan Meher, Vanitha Raj R, Vinay R Pandit, Narendra K Bodhey","doi":"10.1177/00494755241298875","DOIUrl":"10.1177/00494755241298875","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"166-168"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender-based violence against female patients in hospitals. 针对医院女病人的性别暴力。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-02-06 DOI: 10.1177/00494755251318089
Surajit Bhattacharya, Kaushik Bhattacharya, Neeta Bhattacharya, Neela Bhattacharya
{"title":"Gender-based violence against female patients in hospitals.","authors":"Surajit Bhattacharya, Kaushik Bhattacharya, Neeta Bhattacharya, Neela Bhattacharya","doi":"10.1177/00494755251318089","DOIUrl":"10.1177/00494755251318089","url":null,"abstract":"<p><p>Gender-based violence (GBV) against female patients in Indian hospitals is an under-recognized but critical issue that undermines the principles of equitable healthcare. This phenomenon encompasses physical, verbal, emotional, and structural abuse, often exacerbated by deeply entrenched societal norms, gender discrimination, and systemic inefficiencies in healthcare delivery. Female patients in India frequently encounter GBV in its various forms, namely neglect, inappropriate physical contact, discriminatory attitudes, and breaches of confidentiality. Women from marginalized communities (lower socio-economic or minority groups) are particularly vulnerable. Contributing factors include insufficient privacy protocols, overburdened healthcare facilities, inadequate staff training on gender sensitivity, and power dynamics, all of which particularly disadvantage female patients. The consequences of GBV are profound, leading to psychological trauma, diminished trust in healthcare systems, or delayed or avoided medical care. Despite its prevalence, GBV in Indian hospital settings remains under-reported owing to fear of stigma, societal pressure, and lack of accessible reporting mechanisms.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"96-99"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant renal angiomyolipomas in tuberous sclerosis complex. 结节性硬化症并发巨大肾血管平滑肌脂肪瘤。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2024-12-09 DOI: 10.1177/00494755241303808
Rakesh Kodati, Narendra Kumar Narahari, Visweswaran Balasubramanian, Sriharish Vankayalapati, Anu Kapoor, Parmajyothi Gongati
{"title":"Giant renal angiomyolipomas in tuberous sclerosis complex.","authors":"Rakesh Kodati, Narendra Kumar Narahari, Visweswaran Balasubramanian, Sriharish Vankayalapati, Anu Kapoor, Parmajyothi Gongati","doi":"10.1177/00494755241303808","DOIUrl":"10.1177/00494755241303808","url":null,"abstract":"<p><p>Angiomyolipomas are the benign tumours of the kidney which occur either sporadically or in association with tuberous sclerosis complex (TSC). Symptoms typically develop with an increase in the size of the lesion. We present a clinical image of a patient with giant renal angiomyolipomas who had other clinical features of TSC (facial angiofibromas, periungual fibroma, subependymal nodules in the brain, and lung cysts).</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"172-173"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of typhoid fever in dengue patients: Insights from a retrospective study at a tertiary care hospital in Delhi. 登革热患者伤寒的流行：来自德里一家三级保健医院回顾性研究的见解。
IF 0.5 4区 医学
Tropical Doctor Pub Date : 2025-04-01 Epub Date: 2025-02-03 DOI: 10.1177/00494755251317562
Anandi Goel, Arpita Panda, Belinda Jothi J, Monika Matlani, Shilpee Kumar, Deepthi Nair
{"title":"Prevalence of typhoid fever in dengue patients: Insights from a retrospective study at a tertiary care hospital in Delhi.","authors":"Anandi Goel, Arpita Panda, Belinda Jothi J, Monika Matlani, Shilpee Kumar, Deepthi Nair","doi":"10.1177/00494755251317562","DOIUrl":"10.1177/00494755251317562","url":null,"abstract":"","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"131-133"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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