Ultraschall in Der Medizin最新文献_第6页

Fetal cardiovascular function in a late-onset SGA and FGR cohort: CURIOSA study. 晚期 SGA 和 FGR 队列中的胎儿心血管功能：CURIOSA 研究。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-11-06 DOI: 10.1055/a-2390-2010

Silvia M Lobmaier, Oliver Graupner, Christina Franke, Nadia Boess, Bernhard Haller, Renate Oberhoffer, Annette Wacker-Gussmann, Javier U Ortiz

{"title":"Fetal cardiovascular function in a late-onset SGA and FGR cohort: CURIOSA study.","authors":"Silvia M Lobmaier, Oliver Graupner, Christina Franke, Nadia Boess, Bernhard Haller, Renate Oberhoffer, Annette Wacker-Gussmann, Javier U Ortiz","doi":"10.1055/a-2390-2010","DOIUrl":"10.1055/a-2390-2010","url":null,"abstract":"The measurement of fetal cardiovascular function parameters is not yet established in prenatal diagnostics. Now that the research field of fetal programming is becoming increasingly important, this might change. Fetal cardiovascular changes have been described above all in early/severe fetal growth restriction (FGR). The aim of this study was to investigate functional echocardiographic parameters in fetuses with late-onset small for gestational age (SGA)/FGR.A prospective cohort of SGA fetuses (including FGR) and a control group with similar distribution of gestational age were studied. Parameters of systolic, diastolic, and global cardiac function, morphometry and measurements of the fetal abdominal aorta were collected.A total of 149 SGA fetuses and 143 control fetuses were included from 32 weeks until term. The total SGA group was further divided into SGA 3rd-10th (fetuses between the 3rd and 10th weight percentile) and FGR subgroups. In the total SGA group, relative right and left ventricular wall thickness, left E/A ratio, isovolumetric contraction time and left myocardial performance index were significantly increased compared to controls after adjustment for gestational age. MAPSE, TAPSE, ejection time, left cardiac output, and abdominal aortic distensibility were significantly lower. The changes were more pronounced in the FGR subgroup.Even in a group of late-onset SGA/FGR, echocardiographic parameters are already altered in utero.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remote out-of-hours ultrasound live supervision in pediatrics - improvement of diagnostics and training. 儿科远程非工作时间超声波现场督导--改进诊断和培训。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-11-04 DOI: 10.1055/a-2421-8319

Metin Cetiner, Selin Kavuk, Ilja Finkelberg, Martin Kreuzer, Christine Okorn, Benas Prusinskas, Felix Schiepek, Johannes Jägers, Lars Pape, Anja Büscher

{"title":"Remote out-of-hours ultrasound live supervision in pediatrics - improvement of diagnostics and training.","authors":"Metin Cetiner, Selin Kavuk, Ilja Finkelberg, Martin Kreuzer, Christine Okorn, Benas Prusinskas, Felix Schiepek, Johannes Jägers, Lars Pape, Anja Büscher","doi":"10.1055/a-2421-8319","DOIUrl":"10.1055/a-2421-8319","url":null,"abstract":"Purpose: Ultrasound (US) is the preferred imaging modality in pediatrics for diagnostic and therapeutic issues. The absence of radiation and the constant on-site accessibility make it the ideal tool for children. However, despite remarkable technical advances in resolution and applicability, many sophisticated medical questions still require profound expertise on the part of the examiner, thus often hampering fast decisions particularly outside regular working hours.Materials and methods: This single-center study, at a university children's hospital evaluated the use of US during emergency service. A four-week documentation period was followed by a subsequent eight-week supervision period with live supervision availability on demand guided by a remote US expert. The demand for expert support, diagnosis, grading of urgency, duration and success of examination, and satisfaction of both examiners were analyzed.Results: 108 patients (mean age 9.7 years) were included. In 38% of cases, US was supervised on demand with a definite diagnosis in 92.6% of cases (25/27). Image quality and technical performance were graded sufficient in 100% of cases. Supervised compared to non-supervised US examinations were prolonged (14.4 min vs. 7.1 min, p<0.001), were more prevalent within the first 24 h in the hospital (70% vs. 56.8%, p=0.06), and were classified more frequently as emergency (22.2% vs. 2.3%; p=0.015). All participants classified the availability of US supervision as decisively helpful.Conclusion: Remote live supervised pediatric US was feasible and effective. It combined timely, high-quality diagnostics even in the case of challenging medical questions with simultaneous US training.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of placenta and fetal lung using shear wave elastography in gestational diabetes mellitus: An innovative approach. 利用剪切波弹性成像技术评估妊娠糖尿病患者的胎盘和胎肺：一种创新方法

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-11-04 DOI: 10.1055/a-2323-0941

Burak Bayraktar, Hakan Golbasi, Ibrahim Omeroglu, Ceren Golbasi, Sevim Tuncer Can, Onur Ince, Miyase Gizem Bayraktar, Mehmet Ozer, Atalay Ekin

{"title":"Evaluation of placenta and fetal lung using shear wave elastography in gestational diabetes mellitus: An innovative approach.","authors":"Burak Bayraktar, Hakan Golbasi, Ibrahim Omeroglu, Ceren Golbasi, Sevim Tuncer Can, Onur Ince, Miyase Gizem Bayraktar, Mehmet Ozer, Atalay Ekin","doi":"10.1055/a-2323-0941","DOIUrl":"10.1055/a-2323-0941","url":null,"abstract":"Purpose: This study aims to investigate placental and fetal lung stiffness in pregnant women with and without gestational diabetes, considering the well-established delay in fetal lung maturation associated with gestational diabetes.Materials and methods: This prospective cohort study was conducted at a tertiary center and included pregnant women who underwent a 75-gram oral glucose tolerance test between 24-28 weeks of gestation. Elastography measurements were performed using point shear wave elastography (pSWE).Results: The study included 60 pregnant women diagnosed with gestational diabetes and 60 pregnant women in the control group. The SWE velocity of the peripheral placenta, central placenta, and lung was higher in the gestational diabetes group compared to the control group. Furthermore, the SWE velocity of the peripheral placenta, central placenta, and lung was higher in newborns with neonatal respiratory morbidity. Based on the ROC analysis of patients with gestational diabetes, the AUC for lung SWE velocity was 0.88 (cut-off 12.4 kPa, 95% CI: 0.77-0.99, p<0.001) with a sensitivity of 71.4% and specificity of 95.6% for predicting neonatal respiratory morbidity.Conclusion: Fetal placental and lung stiffness increase in fetuses of pregnant women with diabetes. Moreover, higher fetal lung stiffness during the fetal period is associated with increased neonatal respiratory morbidity.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140905171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kaposiform haemangioendothelioma: ultrasonographic features and risk factors for the Kasabach-Merritt phenomenon. 楷模状血管内皮瘤：超声特征和 Kasabach-Merritt 现象的风险因素。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-10-15 DOI: 10.1055/a-2421-6047

Jing Zhao, Jian-Jun Yuan, Chang-Xian Dong, Xiangqin Zhang, Chuang Li, Qi Sun, Gang Wu

{"title":"Kaposiform haemangioendothelioma: ultrasonographic features and risk factors for the Kasabach-Merritt phenomenon.","authors":"Jing Zhao, Jian-Jun Yuan, Chang-Xian Dong, Xiangqin Zhang, Chuang Li, Qi Sun, Gang Wu","doi":"10.1055/a-2421-6047","DOIUrl":"https://doi.org/10.1055/a-2421-6047","url":null,"abstract":"Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular tumor with high morbidity and mortality. The aim of this study was to evaluate ultrasonographic findings associated with KHE.The clinical and ultrasonographic findings of a cohort of 64 cases with pathologically proven KHE were retrospectively reviewed and analyzed between November 2014 and February 2021. Two subtypes were divided according to the presence or absence of the Kasabach-Merritt phenomenon (KMP). The KMP risk factors in patients with KHE were analyzed statistically.Among the 64 cases of KHE, 43 (67.2%) were accompanied by KMP. There was a positive correlation between the appearance of KMP and tumor size. KHEs had an increased risk of developing KMP if the lesions measured were >6 cm and if they belonged to the deep or mixed subtype. On ultrasonography, all KHE lesions were heterogeneous, and 81.3% were hypoechoic; 93.8% of KHEs exhibited ill-defined margins, 68.7% had strands branching into the adjacent tissue, and 84.4% presented marked hypervascularity. Elastography showed that central hypoechogenic lesion areas were hard, and surrounding hyperechogenic lesion areas were soft.KHEs can occur in different parts of childrens' bodies. On ultrasonography, the main findings are heterogeneous low erosions, indistinct margins, branching strangulation into adjacent tissues, and obvious hypervascularity. Patients with lesions larger than 6 cm or belonging to deep or mixed subtypes (musculoskeletal infiltrates) are at risk for developing KMP, and clinicians should be vigilant.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Real-time carotid plaque recognition from dynamic ultrasound videos based on artificial neural network. 基于人工神经网络从动态超声视频中实时识别颈动脉斑块

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-10-01 Epub Date: 2023-12-19 DOI: 10.1055/a-2180-8405

Yao Wei, Bin Yang, Ling Wei, Jun Xue, Yicheng Zhu, Jianchu Li, Mingwei Qin, Shuyang Zhang, Qing Dai, Meng Yang

{"title":"Real-time carotid plaque recognition from dynamic ultrasound videos based on artificial neural network.","authors":"Yao Wei, Bin Yang, Ling Wei, Jun Xue, Yicheng Zhu, Jianchu Li, Mingwei Qin, Shuyang Zhang, Qing Dai, Meng Yang","doi":"10.1055/a-2180-8405","DOIUrl":"10.1055/a-2180-8405","url":null,"abstract":"Purpose: Carotid ultrasound allows noninvasive assessment of vascular anatomy and function with real-time display. Based on the transfer learning method, a series of research results have been obtained on the optimal image recognition and analysis of static images. However, for carotid plaque recognition, there are high requirements for self-developed algorithms in real-time ultrasound detection. This study aims to establish an automatic recognition system, Be Easy to Use (BETU), for the real-time and synchronous diagnosis of carotid plaque from ultrasound videos based on an artificial neural network.Materials and methods: 445 participants (mean age, 54.6±7.8 years; 227 men) were evaluated. Radiologists labeled a total of 3259 segmented ultrasound images from 445 videos with the diagnosis of carotid plaque, 2725 images were collected as a training dataset, and 554 images as a testing dataset. The automatic plaque recognition system BETU was established based on an artificial neural network, and remote application on a 5G environment was performed to test its diagnostic performance.Results: The diagnostic accuracy of BETU (98.5%) was consistent with the radiologist's (Kappa = 0.967, P < 0.001). Remote diagnostic feedback based on BETU-processed ultrasound videos could be obtained in 150ms across a distance of 1023 km between the ultrasound/BETU station and the consultation workstation.Conclusion: Based on the good performance of BETU in real-time plaque recognition from ultrasound videos, 5G plus Artificial intelligence (AI)-assisted ultrasound real-time carotid plaque screening was achieved, and the diagnosis was made.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"493-500"},"PeriodicalIF":3.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138812365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic ultrasound-guided ethanol ablation versus surgical resection of insulinomas. 内镜超声引导下乙醇消融与胰岛素瘤手术切除的比较。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-10-01 Epub Date: 2023-11-06 DOI: 10.1055/a-2204-5814

Christian Jürgensen, Marius Eckart, Linus Haberbosch, Frank Tacke, Arvid Sandforth, Andreas L Birkenfeld, Dietrich Overkamp, Martin Daniels, Martina Mogl, Peter Goretzki, Christian Strasburger, Knut Mai, Joachim Spranger, Reiner Jumpertz von Schwartzenberg

{"title":"Endoscopic ultrasound-guided ethanol ablation versus surgical resection of insulinomas.","authors":"Christian Jürgensen, Marius Eckart, Linus Haberbosch, Frank Tacke, Arvid Sandforth, Andreas L Birkenfeld, Dietrich Overkamp, Martin Daniels, Martina Mogl, Peter Goretzki, Christian Strasburger, Knut Mai, Joachim Spranger, Reiner Jumpertz von Schwartzenberg","doi":"10.1055/a-2204-5814","DOIUrl":"10.1055/a-2204-5814","url":null,"abstract":"Purpose: Insulinoma is a rare tumor of the pancreas that can lead to hypoglycemia. To date, the standard therapy is surgical resection. After the first case report of successful endoscopic ultrasound-guided (EUS) ethanol injection 16 years ago, the need for establishing an alternative treatment method remains unchanged given the high morbidity rates of surgery and its unsuitability in some patients.Materials and methods: Here, we provide retrospective data from 33 insulinoma patients that were treated at our center between 2010 and 2021. Of these, 9 patients were treated with EUS-guided ethanol injection and 24 underwent pancreatic surgery.Results: The ethanol group was older (ethanol: mean ± SE 67.8±11.2 years vs. surgery: 52.3±15.7, p=0.014) with a higher Charlson Comorbidity Index (3.0 (1.0;4.0) vs. 1.0 (0.0;2.0), p=0.008). The lowest glucose values were similar between groups before (ethanol: 2.09±0.17 mmol/l vs. surgery: 1.81±0.08, p=0.158) and after (4.95±0.74 vs. 5.41±0.28, p=0.581) the respective treatments. Complications occurred more frequently in the surgery group (11 % vs. 54 %, p=0.026). One patient after prior partial pancreatectomy died postoperatively. The hospitalization time was significantly shorter in the ethanol group (4.78±0.78 days vs. 19.88±4.07, p<0.001).Conclusion: EUS-guided ethanol injection can be similarly effective for the treatment of hyperinsulinemic hypoglycemia compared with pancreatic surgery but seems to be associated with less severe complications. This implies the need for prospective randomized trials in insulinoma patients with a low risk for malignancy.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"519-527"},"PeriodicalIF":3.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71488017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bridging the notch: quantification of the end diastolic notch to better predict fetal growth restriction. 连接缺口：量化舒张末期切迹，更好地预测胎儿生长受限。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-10-01 Epub Date: 2024-01-31 DOI: 10.1055/a-2257-8557

Sheila Yu, Ananya Gopika Nair, Tianhua Huang, Nir Melamed, Elad Mei Dan, Amir Aviram

{"title":"Bridging the notch: quantification of the end diastolic notch to better predict fetal growth restriction.","authors":"Sheila Yu, Ananya Gopika Nair, Tianhua Huang, Nir Melamed, Elad Mei Dan, Amir Aviram","doi":"10.1055/a-2257-8557","DOIUrl":"10.1055/a-2257-8557","url":null,"abstract":"Purpose: We aimed to evaluate several quantitative methods to describe the diastolic notch (DN) and compare their performance in the prediction of fetal growth restriction.Materials and methods: Patients who underwent a placental scan at 16-26 weeks of gestation and delivered between Jan 2016 and Dec 2020 were included. The uterine artery pulsatility index was measured for all of the patients. In patients with a DN, it was quantified using the notch index and notch depth index. Odds ratios for small for gestational age neonates (defined as birth weight <10th and <5th percentile) were calculated. Predictive values of uterine artery pulsatility, notch, and notch depth index for fetal growth restriction were calculated.Results: Overall, 514 patients were included, with 69 (13.4%) of them delivering a small for gestational age neonate (birth weight<10th percentile). Of these, 20 (20.9%) had a mean uterine artery pulsatility index >95th percentile, 13 (18.8%) had a unilateral notch, and 11 (15.9%) had a bilateral notch. 16 patients (23.2%) had both a high uterine artery pulsatility index (>95th percentile) and a diastolic notch. Comparison of the performance between uterine artery pulsatility, notch, and notch depth index using receiver operating characteristic curves to predict fetal growth restriction <10th percentile found area under the curve values of 0.659, 0.679, and 0.704, respectively, with overlapping confidence intervals.Conclusion: Quantifying the diastolic notch at 16-26 weeks of gestation did not provide any added benefit in terms of prediction of neonatal birth weight below the 10th or 5th percentile for gestational age, compared with uterine artery pulsatility index.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"501-508"},"PeriodicalIF":3.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

B-Mode Ultrasound and Contrast-Enhanced Ultrasound for the Detection of Splenic Involvement in Hodgkin Lymphoma: A Retrospective Analysis of 112 Patients. B型超声和对比增强超声检测霍奇金淋巴瘤脾脏受累：112例患者的回顾性分析。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-10-01 Epub Date: 2023-10-20 DOI: 10.1055/a-2173-2361

Hajo Findeisen, Christian Görg, Helen Winter, Corinna Trenker, Christoph F Dietrich, Amjad Alhyari, Friederike Eilsberger, Ehsan Safai Zadeh

{"title":"B-Mode Ultrasound and Contrast-Enhanced Ultrasound for the Detection of Splenic Involvement in Hodgkin Lymphoma: A Retrospective Analysis of 112 Patients.","authors":"Hajo Findeisen, Christian Görg, Helen Winter, Corinna Trenker, Christoph F Dietrich, Amjad Alhyari, Friederike Eilsberger, Ehsan Safai Zadeh","doi":"10.1055/a-2173-2361","DOIUrl":"10.1055/a-2173-2361","url":null,"abstract":"Purpose: To assess splenic involvement using B-mode ultrasound (US) and contrast-enhanced ultrasound (CEUS) compared with standard imaging with contrast-enhanced computerized tomography (CT) / 18-fluorodeoxyglucose positron-emission tomography (PET-CT) in patients with Hodgkin lymphoma.Materials and methods: Imaging data from 112 patients from 12/2003 to 10/2022 with histologically confirmed Hodgkin lymphoma during staging or relapse were analyzed for splenic lymphoma involvement. In all patients, standard imaging (CT/PET-CT), along with B-mode US and CEUS examinations, was performed. Evidence of focal splenic lesions (FSLs) found by imaging procedures was suggestive of splenic involvement. Follow-up imaging was performed in each patient after treatment, and treatment response indicated definitive splenic involvement.Results: 40 patients (35.7%) were identified by imaging modalities as having splenic involvement, which was confirmed by response during follow-up. Standard CT/PET-CT imaging detected splenic involvement in 36/112 patients (32.1%). FSLs were detected with B-mode US in 38 patients (33.9%) and CEUS in 36 patients (32.1%). The sensitivity of standard imaging, B-mode US, and CEUS was 90%, 95%, and 90%, respectively.Conclusion: B-mode US examination is a diagnostic method used in addition to standard imaging for the detection of splenic involvement in Hodgkin lymphoma. CEUS does not provide additional benefit compared to B-mode US and the standard reference procedure.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"484-492"},"PeriodicalIF":3.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49684179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contrast-enhanced ultrasound reveals perfusion differences between benign lipoma and semi-malignant atypical lipomatous tumors: A prospective clinical study. 超声造影显示良性脂肪瘤和半恶性非典型脂肪瘤之间的灌注差异：一项前瞻性临床研究。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-10-01 Epub Date: 2023-10-11 DOI: 10.1055/a-2189-5412

Paul Mick, Antonia Seeberger, Tobias Renkawitz, Burkhard Lehner, Mustafa Hariri, Christian Fischer, Julian Doll

{"title":"Contrast-enhanced ultrasound reveals perfusion differences between benign lipoma and semi-malignant atypical lipomatous tumors: A prospective clinical study.","authors":"Paul Mick, Antonia Seeberger, Tobias Renkawitz, Burkhard Lehner, Mustafa Hariri, Christian Fischer, Julian Doll","doi":"10.1055/a-2189-5412","DOIUrl":"10.1055/a-2189-5412","url":null,"abstract":"Purpose: Soft tissue tumors (STT) are difficult to diagnose accurately, and distinguishing between benign and malignant tumors is challenging. Lipoma is the most common STT, while atypical lipomatous tumors (ALT) can dedifferentiate into malignant lipomatous tumors like grade 1 liposarcoma and require more radical therapy. This study aims to investigate the potential of contrast-enhanced ultrasound (CEUS) to differentiate between lipoma and ALT based on tumor perfusion.Materials and methods: We prospectively examined 52 patients who were scheduled for biopsy for suspected lipoma or ALT. The CEUS examination was performed using SonoVue as a contrast agent to quantify tumor perfusion using VueBox V7.1 software. Peak enhancement (PE), rise time (RT), wash-in perfusion index (WiPI), and wash-out rate (WoR) were used to assess contrast enhancement inside the STT.Results: Among 50 tumors examined, 30 were lipomas, and 20 were ALTs. We found significant differences in perfusion between lipomas and ALTs (PE: 49.22 ± 45.75 a.u. vs. 165.67 ± 174.80; RT: 23.86 ± 20.47s vs. 10.72 ± 5.34 s; WiPI: 33.06 ± 29.94 dB vs. 107.21 ± 112.43 dB; WoR: 2.44 ± 3.70 dB/s vs. 12.75 ± 15.80 dB/s; p<.001). ROC analysis of PE resulted in a diagnostic accuracy of 74% for the detection of an ALT, and 77% for the detection of a lipoma.Conclusion: CEUS may enhance the differential diagnosis of benign lipomas and ALTs, with ALTs showing higher levels of perfusion. If larger prospective studies confirm these findings, CEUS could enhance diagnostic accuracy, guide surgical planning, and potentially reduce unnecessary treatments for patients presenting with ambiguous lipomatous tumors like lipoma or ALT.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"509-518"},"PeriodicalIF":3.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41217741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial intelligence in Ultrasound: Pearls and pitfalls in 2024. 超声波领域的人工智能：2024 年的珍珠和陷阱超声波领域的人工智能：2024 年的珍珠和陷阱。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2024-10-01 Epub Date: 2024-09-06 DOI: 10.1055/a-2368-9201

Bernardo Stefanini, Alice Giamperoli, Eleonora Terzi, Fabio Piscaglia

引用次数: 0