Marco Becciolini, Giorgio Tamborrini, Christopher Pivec, Georg Riegler
{"title":"Ultrasound findings in 46 cases of incomplete release of the transverse carpal ligament in carpal tunnel surgery.","authors":"Marco Becciolini, Giorgio Tamborrini, Christopher Pivec, Georg Riegler","doi":"10.1055/a-2672-2835","DOIUrl":"10.1055/a-2672-2835","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the ultrasound (US) features of a complication in patients who have undergone surgery for carpal tunnel syndrome (CTS): the incomplete release of the transverse carpal ligament (TCL).</p><p><strong>Materials and methods: </strong>Reports from two institutions were searched using the keywords \"persistent CTS\" and \"incomplete TCL release\". Post-surgical US examinations were performed using a standardized approach at both institutions, first assessing the muscles supplied by the median nerve (MN) and then conducting a detailed evaluation of the MN course at the wrist. To avoid misinterpreting ligament regrowth, patients with recurrent symptoms two months or later after surgery were excluded. Only cases showing clear compression by the TCL were selected.</p><p><strong>Results: </strong>A total of 46 patients were identified with incomplete release of the TCL, with the average uncut portion of the ligament measuring 6.7 mm. The proximal margin of the TCL was incompletely released in 65% of the cases, while the distal margin was affected in 35%. Symptoms in these patients persisted after surgery, and, in 52%, they were worse than before surgery. A reduction in thenar muscle bulk was observed in 37 patients. Follow-up clinical data were available in eight patients, with three undergoing US evaluation after revision surgery.</p><p><strong>Conclusion: </strong>US can effectively demonstrate the incomplete release of the TCL, visualized as a fibrillar uncut structure compressing the MN and producing an hourglass appearance of the nerve. In addition, US may help detect other factors that contribute to persistent symptoms and help to guide revision surgery.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"284-293"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145985779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Henrique Moraes, Maria Cristina Chammas, Felipe Brasileiro Vanderlei, Marcelo Violi Schelini, Carolina De Marqui Milani, Danielle Azevedo Chacon
{"title":"2D-Shear Wave Elastography Increases the Diagnostic Accuracy of the TIRADS-ACR and ATA Classification Systems in Thyroid Nodule Selection: Cytological and Histological Correlation.","authors":"Pedro Henrique Moraes, Maria Cristina Chammas, Felipe Brasileiro Vanderlei, Marcelo Violi Schelini, Carolina De Marqui Milani, Danielle Azevedo Chacon","doi":"10.1055/a-2551-7774","DOIUrl":"10.1055/a-2551-7774","url":null,"abstract":"<p><strong>Purpose: </strong>The aim was to evaluate whether elastography changes the accuracy of thyroid nodule malignancy risk classification using the TI-RADS ACR and ATA systems.</p><p><strong>Materials and methods: </strong>This was a prospective study with 191 nodules (180 patients). Nodule assessments by B-mode ultrasonography (US) and 2-dimensional shear wave elastography (2D-SWE) were compared with a) fine-needle aspiration biopsy cytological (Bethesda II) and b) post-resection histology results (Bethesda III-VI). Nodules were divided into benign and malignant. B-mode US evaluated echogenicity, composition, dimensions, contours, limits, and presence of halo and echogenic foci. Elastography classified nodules from I (completely softened) to IV (completely hard). The mean nodule deformation value (assessed in m/s and kPa), the deformation ratio between nodule and thyroid parenchyma (TDR), and the deformation ratio between nodule and pre-thyroid musculature (MDR) were calculated.</p><p><strong>Results: </strong>The significant univariate parameters for B-mode were hypoechogenicity, halo, microcalcifications, irregular contours, and ill-defined limits. All parameters were significant for elastography. The MDR (in kPa) was the best elastographic parameter: nodules with MDRs> 1.53 exhibited a higher chance of malignancy (AUC-ROC=0.831). B-mode ACR-TIRADS had an AUC of 0.678; 95% CI: 0.596-0.760, while ATA had an AUC of 0.680; 95%: 0.597-0.763. Multivariable analysis indicated that the combination of prognostic models with any elastographic parameter increased performance. ATA classification, combined with elastogram pattern and MDR (in kPa), increased the AUC to 0.892; 95% IC: 0.845-0.939.</p><p><strong>Conclusion: </strong>2D-SWE can increase the accuracy of the most widespread B-mode prognostic models: TI-RADS ACR and ATA.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"263-274"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk-based ultrasound probe quality assurance - a single center proof-of-concept study.","authors":"Bálint Botz","doi":"10.1055/a-2408-0259","DOIUrl":"10.1055/a-2408-0259","url":null,"abstract":"<p><strong>Purpose: </strong>Ultrasound probe quality assurance is an underserved and underregulated area in medical imaging. While several testing methods exist, their availability and adoption remains varied, and the frequency of testing is often insufficient. Here we aimed to conduct a user-driven simple and rapid probe quality testing approach and to evaluate its rationale.</p><p><strong>Materials and methods: </strong>Testing was based on physical examination of probe integrity (all probes) and in-air reverberation check (for curvilinear and linear array probes), findings, as well as probe age were registered. Prior to assessment, probes were divided into a high-risk vs. a low-risk category, based on the perceived risk of probe damage as a result of the typical application (e.g., non-invasive vs. interventional, inpatient vs. point-of-care).</p><p><strong>Results: </strong>17.4% of the low-risk and 31.4% of high-risk probes demonstrated physical wear or damage. Reverberation artifacts were significantly more frequent (68%) in the high-risk category vs. the low-risk one (29.4%). Probes with either physical or reverberation faults were significantly older on average.</p><p><strong>Conclusion: </strong>The simple, rapid investigational technique uncovered an alarming percentage of probe damage or faults. It also identified immediately solvable technical issues (e.g., poor cable contact mimicking dropout). High-risk probe usage resulted in an increased rate of reverberation errors and physical damage. Risk-based, frequent rapid observational testing of ultrasound probes could substantially improve both diagnostic quality and patient safety.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"294-299"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is the hyper-defense of current patients in clinical research reducing the expectations for the cure of future patients? The case of investigator-initiated imaging and treatment studies becoming no longer sustainable.","authors":"Fabio Piscaglia, Viola Tarterini, Francesca Girolami, Bernardo Stefanini","doi":"10.1055/a-2831-6814","DOIUrl":"https://doi.org/10.1055/a-2831-6814","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":"47 3","pages":"222-224"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148220316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vito Cantisani, Maija Radzina, Christoph F Dietrich, Christian Jenssen, Helmut Prosch, Liat Appelbaum, Richard G Barr, Kunwar S S Bhatia, Manjiri Dighe, Cosimo Durante, Daniele Fresilli, Giorgio Grani, Chris Harvey, Pintong Huang, Gordana Ivanac, Adrian Lim, Süha Süreyya Özbek, Mustafa Secil, Tobias Todsen, Pierpaolo Trimboli
{"title":"EFSUMB Guidelines on Multiparametric Ultrasound Thyroid Nodule Evaluation: PART I.","authors":"Vito Cantisani, Maija Radzina, Christoph F Dietrich, Christian Jenssen, Helmut Prosch, Liat Appelbaum, Richard G Barr, Kunwar S S Bhatia, Manjiri Dighe, Cosimo Durante, Daniele Fresilli, Giorgio Grani, Chris Harvey, Pintong Huang, Gordana Ivanac, Adrian Lim, Süha Süreyya Özbek, Mustafa Secil, Tobias Todsen, Pierpaolo Trimboli","doi":"10.1055/a-2761-1191","DOIUrl":"10.1055/a-2761-1191","url":null,"abstract":"<p><strong>Abstract: </strong>Thyroid nodules are common incidental findings, but only a small proportion of cases are malignant (4-6.5%) or symptomatic. Numerous follow-up examinations and invasive diagnostic procedures, such as fine-needle aspiration, fine-needle biopsies, and thyroidectomies, are performed, leading to potentially costly and time-consuming diagnostic procedures and overtreatment. Most experts and scientific societies (EFSUMB, WFUMB, etc.) encourage the use of multiparametric ultrasound evaluation (MPUS) to improve thyroid nodule characterization due to the continuous technological developments including new ultrasound software (microvascular flow imaging, elastosonography, etc.), contrast media (CEUS), and artificial intelligence (AI). Therefore, the recognition and proper use of new multiparametric ultrasound features of thyroid nodules are essential for minimizing unnecessary interventions and guiding appropriate treatment. The goal of these guidelines is to help initiate use of these features in routine clinical practice. In addition, we analyze the use of MPUS in some emblematic thyroid scenarios, such as cytologically indeterminate nodules, multinodular goiters, and extrathyroidal extension of the malignant nodule, and the usefulness of MPUS as a guide for thyroid biopsy/aspiration and in the staging of cervical lymph nodes. Recommendations based on the level of evidence of the published literature and on the EFSUMB expert group's consensus are given for each question.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"253-262"},"PeriodicalIF":3.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Hashim, Alice Giamperoli, Madalina-Gabriela Indre, Fabio Piscaglia
{"title":"The application of Artificial Intelligence in the ultrasound-based diagnosis of liver disease: current status, hurdles, and prospects.","authors":"Ahmed Hashim, Alice Giamperoli, Madalina-Gabriela Indre, Fabio Piscaglia","doi":"10.1055/a-2809-9211","DOIUrl":"10.1055/a-2809-9211","url":null,"abstract":"<p><strong>Abstract: </strong>Over the past decade, there has been marked progress in artificial intelligence (AI) and its application in medicine. In the field of hepatology, AI can aid in predicting disease risk and prognosis, optimizing patient care through improvements in diagnostic efficiency, and developing therapeutic strategies. Therefore, it seems that physicians must become more acquainted with the different AI modalities and their potential applications. In this article, we explore the current status and applications of AI in liver ultrasound illustrating the key principles and concepts in the field. We also highlight the main obstacles facing AI implementation in clinical practice and the potential future benefits and directions.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"226-252"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147845083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ehsan Safai Zadeh, Christian Görg, Hajo Findeisen, Philip Eckwolf, Lea Dibon, Helmut Prosch
{"title":"Contrast-enhanced ultrasound (CEUS) is helpful for the characterization of solitary fibrous tumors of the pleura.","authors":"Ehsan Safai Zadeh, Christian Görg, Hajo Findeisen, Philip Eckwolf, Lea Dibon, Helmut Prosch","doi":"10.1055/a-2627-8336","DOIUrl":"10.1055/a-2627-8336","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the perfusion patterns of solitary fibrous tumors of the pleura (SFTP) using contrast-enhanced ultrasound (CEUS).</p><p><strong>Materials and methods: </strong>Between November 2012 and 2024, six patients with histologically confirmed SFTP underwent B-mode ultrasound (B-US) and CEUS. Parameters from the arterial phase, including flow-in pattern, extent of enhancement (EE; marked or reduced/absent), and homogeneity of enhancement (HE; homogeneous or inhomogeneous) were retrospectively analyzed.</p><p><strong>Results: </strong>All 6 lesions displayed a flow-in perfusion pattern that originated from a peripheral point. Five lesions (83.3%) exhibited arterial hyperenhancement and 1 (16.7%) showed hypoenhancement. HE was inhomogeneous in 5 lesions (83.3%) and homogeneous in 1 (16.7%).</p><p><strong>Conclusion: </strong>On CEUS, all cases showed an arterial flow-in perfusion that originated from a peripheral point in an SFT, which could be a diagnostic clue for the non-invasive diagnosis of SFTPs. Given the risk of tumor seeding, direct surgical resection may be preferable to biopsy in these cases.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"300-305"},"PeriodicalIF":3.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13288283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriel Eisenkolb, Chiara Lecce, Nina Draeger, Anne Karge, Silvia M Lobmaier, Kathrin Abel, Eva Ostermayer, Bettina Kuschel, Javier U Ortiz, Oliver Graupner
{"title":"Value of cerebroplacental ratio in predicting adverse perinatal outcome in uncomplicated twin pregnancies: a retrospective study.","authors":"Gabriel Eisenkolb, Chiara Lecce, Nina Draeger, Anne Karge, Silvia M Lobmaier, Kathrin Abel, Eva Ostermayer, Bettina Kuschel, Javier U Ortiz, Oliver Graupner","doi":"10.1055/a-2566-8912","DOIUrl":"10.1055/a-2566-8912","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the performance of the cerebroplacental ratio (CPR) in predicting operative delivery for intrapartum fetal compromise (OD for IFC) and adverse perinatal outcomes in uncomplicated twin pregnancies with attempted vaginal delivery.</p><p><strong>Materials and methods: </strong>This was a retrospective cohort study of 72 twin pregnancies in a single tertiary referral center between January 2018 and August 2024. All MCDA and DCDA twin pregnancies with an attempted vaginal delivery after 34+0 weeks were screened for eligibility and those without further risk factors were included in the study. Outcome parameters were OD for IFC and a composite of adverse perinatal outcomes (CAPO) including OD for IFC, 5-minute Apgar score <7, umbilical artery pH <7.10, or admission to the neonatal intensive care unit (NICU). The predictive performance of CPR was evaluated using ROC analyses and multivariable logistic regression.</p><p><strong>Results: </strong>16 MCDA and 56 DCDA pregnancies met the inclusion criteria. CAPO of at least one of the twins occurred in 27 (37.5%) of the cases. ROC analyses showed that low CPR MoM of neither the presenting twin nor the second twin predicted CAPO. Similarly, the prediction of the need for OD for IFC of twin 2 was not possible using low CPR MoM as the predicting variable. However, logistic regression analyses showed that nulliparity and twin-to-twin delivery time interval were independently associated with CAPO.</p><p><strong>Conclusion: </strong>Low CPR MoM was not predictive for CAPO or OD for IFC in uncomplicated twin pregnancies after 34 weeks of gestation. However, nulliparity and twin-to-twin delivery time interval were independently associated with CAPO.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"275-283"},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Denis Terziev, Hanna Wußling, Judith Schaffrath, Christin Busse, Stephan Eisenmann, Valentin Blank
{"title":"Fatal disseminated Rhizomucor pusillus mucormycosis with pulmonary involvement diagnosed by contrast-enhanced ultrasound (CEUS) and transcutaneous biopsy in a patient with acute myeloid leukemia.","authors":"Denis Terziev, Hanna Wußling, Judith Schaffrath, Christin Busse, Stephan Eisenmann, Valentin Blank","doi":"10.1055/a-2809-9260","DOIUrl":"https://doi.org/10.1055/a-2809-9260","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147989678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kim Nylund, Ole Kristian Horpestad, Fredrik Sævik, Odd Helge Gilja
{"title":"Submucosal bowel wall layer thickness predicts endoscopic activity in Crohn's disease.","authors":"Kim Nylund, Ole Kristian Horpestad, Fredrik Sævik, Odd Helge Gilja","doi":"10.1055/a-2789-6390","DOIUrl":"10.1055/a-2789-6390","url":null,"abstract":"<p><strong>Purpose: </strong>Gastrointestinal ultrasound is a well-established method for diagnosing and monitoring Crohn's disease (CD). The aim of this study was to investigate whether wall layer data measured on gastrointestinal ultrasound could predict endoscopic activity in CD.</p><p><strong>Materials and methods: </strong>64 CD patients underwent a gastrointestinal ultrasound examination and endoscopy ± 2 weeks apart in a single-center prospective study. Bowel wall thickness and the thickness of individual wall layers corresponding to the mucosa, submucosa and the proper muscle wall were measured and compared with the simple endoscopic score of Crohn's disease (SES-CD) in the most affected bowel segment where SES-CD >2 was defined as activity.</p><p><strong>Results: </strong>There was increased absolute thickness of the mucosa (1.8 versus 1.1mm, p =0.001), submucosa (2.8 versus 1.2mm, p <0.001), and proper muscle (1.6 versus 1.1mm, p =0.006) in patients with endoscopic activity. After an ROC analysis, Youden's index suggested a 1.8 mm cut-off for submucosal thickness and disease activity resulting in a sensitivity of 90%, specificity of 78.3%, and accuracy of 84.9%. In contrast, a bowel wall thickness of 3 mm had a sensitivity of 97.3%, specificity of 52.0%, and accuracy of 79.0%. The submucosa was also relatively thicker (0.45 versus 0.36, p=0.008), while the proper muscle was relatively thinner (0.25 versus 0.34, p=0.001) in endoscopic activity.</p><p><strong>Conclusion: </strong>Patients with Crohn's disease and endoscopic activity had an increased thickness of all bowel wall layers in affected areas. Measurements of the submucosa may be used to assess disease activity with results similar to bowel wall thickness.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145991606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}