Pedro Henrique Moraes, Maria Cristina Chammas, Felipe Brasileiro Vanderlei, Marcelo Violi Schelini, Carolina De Marqui Milani, Danielle Azevedo Chacon
{"title":"2D Shear Wave Elastography Increases Diagnostic Accuracy of the TIRADS-ACR and ATA Classification System in Thyroid Nodule Selection: Cyto- and Histological Correlation.","authors":"Pedro Henrique Moraes, Maria Cristina Chammas, Felipe Brasileiro Vanderlei, Marcelo Violi Schelini, Carolina De Marqui Milani, Danielle Azevedo Chacon","doi":"10.1055/a-2551-7774","DOIUrl":"https://doi.org/10.1055/a-2551-7774","url":null,"abstract":"<p><strong>Purpose: </strong>The aim was to evaluate whether elastography changes the accuracy of thyroid nodule malignancy risk classification by TI-RADS ACR and ATA systems.</p><p><strong>Materials and methods: </strong>This was a prospective study with 191 nodules (180 patients). Nodule assessments by B-mode ultrasonography (US) and two-dimensional shear wave elastography (2D-SWE) were compared with a) fine-needle aspiration biopsy cytological (Bethesda II) and post-resection histology results (Bethesda III to VI). Nodules were divided into benign and malignant. B-mode US evaluated: echogenicity, composition, dimensions, contours, limits, presence of halo and echogenic foci. Elastography classified nodules from I - completely softened to IV - completely hard; mean nodule deformation value (assessed in m/s and kPa); deformation ratio between nodule and thyroid parenchyma (TDR) and deformation ratio between nodule and prethyroid musculature (MDR).</p><p><strong>Results: </strong>Significant univariate parameters for B-mode: hypoechogenicity, halo, microcalcifications, irregular contours and ill-defined limits; for elastography, all parameters. MDR (in kPa) was the best elastographic parameter: nodules with MDRs> 1.53 exhibited a higher chance of malignancy (AUC-ROC=0.831). B-mode ACR-TIRADS performance had AUC: 0.678; 95% CI: 0.596-0.760 and ATA, AUC: 0.680; 95%: 0.597-0.763. Multivariable analysis indicated that combination of prognostic models with any elastographic parameter increased performance. ATA classification combined with elastogram pattern and MDR (in kPa), increased the AUC to 0.892; 95% IC: 0.845-0.939.</p><p><strong>Conclusion: </strong>2D-SWE can increase accuracy of the most widespread B-mode prognostic models - TI-RADS ACR and ATA.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gábor Szabó, Attila Bokor, Veronika Fancsovits, Ezgi Darici Kurt, Theresa Hudelist, Gernot Hudelist
{"title":"Standardized measurement of the piriformis muscle and the proximal portion of the sacral nerve roots using transvaginal ultrasound.","authors":"Gábor Szabó, Attila Bokor, Veronika Fancsovits, Ezgi Darici Kurt, Theresa Hudelist, Gernot Hudelist","doi":"10.1055/a-2521-9321","DOIUrl":"10.1055/a-2521-9321","url":null,"abstract":"<p><p>To identify the sonomorphological appearance and to measure the thickness of the piriformis muscle (PM) and the proximal portion of the sacral nerve roots S1-S3 in healthy premenopausal women.This prospective multicentric observational study included a consecutive series of women undergoing transvaginal sonography (TVS) at 2 tertiary gynecological referral centers. Standardized assessment of the pelvic organs was performed, followed by an attempt to visualize the right and left PM and sacral nerve roots S1-S3 at their origin in proximity to the sacral neuroforamen. Visualization rates, diameters of the muscle and nerve thickness, and the time needed to identify the PM were recorded.305 patients were included in the study. In 293 women (96.1%), the PM was identified bilaterally. The median diameter of the PM was 18.3mm on the right side and 18.4mm on the left side. S1 nerve roots were successfully identified bilaterally in 224 (73.4%) patients. Their right and left median diameters were 4.8mm. Both S2 nerves were successfully identified in 215 (70.5%) patients. Their median diameter were 4.3mm on both sides. S3 nerve roots were successfully identified in 203 (66.6%) patients. Their median diameter were 3.2mm on both sides.We describe methods which allow consistent and rapid identification of the PM and the S1-S3 sacral nerve roots using TVS. Visualization of the PM and the proximal portion of the sacral plexus may be useful regarding identification of pathological changes in PM thickness and could help to distinguish perineural cysts from other gynecological pathologies.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paul Mick, Katharina Sehmsdorf, Burkhard Lehner, Andreas Geisbüsch, Tobias Renkawitz, Mustafa Hariri, Julian Doll, Stefanos Tsitlakidis
{"title":"Perfusion based malignancy assessment of soft tissue tumors by contrast-enhanced ultrasound (CEUS): a comprehensive analysis of 187 cases.","authors":"Paul Mick, Katharina Sehmsdorf, Burkhard Lehner, Andreas Geisbüsch, Tobias Renkawitz, Mustafa Hariri, Julian Doll, Stefanos Tsitlakidis","doi":"10.1055/a-2549-6101","DOIUrl":"https://doi.org/10.1055/a-2549-6101","url":null,"abstract":"<p><p>English Purpose This study aimed to examine the perfusion characteristics of benign and malignant soft-tissue tumors (STT) using contrast-enhanced ultrasound (CEUS) and correlate STT microperfusion with malignancy. Findings were compared with patient characteristics, clinical presentations, MRI findings, and histopathological outcomes. Methods This prospective single-center study involved patients with unclear STTs who were scheduled for STT biopsy. Clinical assessments and preoperative MRI were conducted along with CEUS. Perfusion quantification was performed, and perfusion parameters (Peak Enhancement (PE), Rise Time, Wash-in Perfusion Index, and Wash-out Rate) were calculated. Perfusion characteristics of different STT were compared. Results 187 patients were included in the final analysis. Significant differences in CEUS perfusion between benign and non-benign STT were demonstrated. Non-benign tumors showed significantly higher tumor perfusion and differences were also significant when comparing semi-malignant, malignant, and metastatic STTs. (PE-Benign 107.74 (34.65-345.62); PE-Semimalignant 166.06 (60.14-374.47); PE-Malignant 1042.24 (358.15-4917.74); PE-Metastasis 2632.37 (2249.46-3788.94). ROC analysis demonstrated a sensitivity of 80% and a PPV of 69% for malignant tumor detection using a cut-off value for Peak Enhancement of 137 [a.u.]. Conclusion CEUS appears to be a promising tool for primary STT evaluation in addition to MRI. Furthermore, it can detect vital areas within the tumor tissue and could be utilized to increase biopsy accuracy. Abstract Deutsch Ziel Es erfolgte eine Analyse der Perfusionscharakteristika verschiedener gutartiger und bösartiger Weichteiltumoren (WTT) mittels kontrastverstärkten Ultraschalls (CEUS). Die Tumor-Mikroperfusion wurde neben MRT-Bildgebung auch mit den histopathologischen Befunden nach Biopsie korreliert, um die prädiktive Qualität des CEUS zur präoperativen Diagnostik unklarer WTT zu untersuchen. Material & Methoden Es wurden Patienten mit unklarem WTT und geplanter offener Biopsie inkludiert. Klinische Untersuchungen und präoperative MRT-Bildgebung wurden durch eine CEUS-Untersuchung ergänzt. Die WTT-Mikroperfusion wurde mittels CEUS quantifiziert und Perfusionsparameter (Peak Enhancement (PE), Rise Time, Wash-in Perfusion Index und Wash-out Rate) berechnet. Die Perfusionscharakteristika verschiedener WTT wurden verglichen. Ergebnisse 187 Patienten wurden inkludiert. Es zeigten sich unter benignen WTT signifikant niedrigere Perfusionsparameter als unter nicht-benignen WTT. Auch im Vergleich von benignen, semimalignen, malignen WTT und Metastasen zeigten sich charakteristische Unterschiede der CEUS-Mikroperfusion (PE-Benigne 107,74 (34,65-345,62); PE-Semi-Maligne 166,06 (60,14-374,47); PE-Maligne 1042,24 (358,15-4917,74); PE-Metastase 2632,37 (2249,46-3788,94). Für die Detektion eines malignen Tumors ergab sich eine Sensitivität von 80% und ein PPV von 69% bei einem Cut-off von PE=137 [a.u.].","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuela Tavares de Sousa, Bettina Hergert, Fatima Crispi, Olga Gomez, Kurt Hecher
{"title":"Imaging the fetal aortic arch and its branching pattern in a midtrimester screening population.","authors":"Manuela Tavares de Sousa, Bettina Hergert, Fatima Crispi, Olga Gomez, Kurt Hecher","doi":"10.1055/a-2548-2411","DOIUrl":"https://doi.org/10.1055/a-2548-2411","url":null,"abstract":"<p><p>Purpose Variants of the aortic arch branching have recently been found to have an impact for neonates undergoing surgical interventions of the thoracic aorta such as repair of aortic coarctation. They have been described prenatally in 6%, whereas they occur in up to 26% postnatally. To explore whether the branching variations might have been under-diagnosed in utero, we comprehensively assessed the aortic arch and its branching patterns in a low-risk population between 19 and 22 weeks of gestation. Material and Methods This prospective cohort study included 139 low-risk singleton pregnancies. During a standardized fetal echocardiography we investigated the aortic arch in a sagittal view according to predefined landmarks. Based on video clips, its branching pattern was categorized in normal branching or branching variants by two operators who were blinded to each other. Results Classification of the aortic arch branching was achieved in 127/139 (91.4%) cases. 103 cases (81.1%) showed a normal pattern and 24 cases (18.9%) a branching variant. Both operators agreed on 18 brachiobicephalic trunks \"(THE SO CALLED BOVINE ARCH)\": , 4 aberrant left vertebral arteries, one aortic arch with five branching vessels and in one case there was disagreement on the type of the variant. Conclusion Prenatal targeted echocardiography could identify a 18.9% prevalence of aortic arch branching variants in a low-risk population. Future studies are warranted to assess the clinical impact of our findings on neonates with congenital heart defects.</p><p><strong>Hintergrund: </strong>Gefäßvarianten der thorakalen Aortenabgänge wurden als Risikofaktoren für Neugeborene identifiziert, die eine Intervention der Aorta, zum Beispiel bei Aortenisthmusstenose, vor sich haben. Pränatal wurde die Häufigkeit mit bis zu 6% beschrieben, während sie postnatal in bis zu 26% gefunden wurden. Um zu untersuchen, ob die Varianten bisher in utero unterdiagnostiziert wurden, untersuchten wir den Aortenbogen und die Abgänge in einer Niedrigrisikogruppe zwischen 19 und 22 Schwangerschaftswochen.</p><p><strong>Material und methoden: </strong>Diese prospektive Kohortenstudie umfasste 139 Einlingsschwangerschaften mit niedrigem Risiko. Während einer standardisierten fetalen Echokardiografie untersuchten wir den Aortenbogen in sagittaler Ebene. Anhand von Videoclips wurden die Abgänge des Aorta von zwei Untersuchenden, die zueinander verblindet waren, entweder als normales Abgangsmuster oder als Variante klassifiziert.</p><p><strong>Ergebnisse: </strong>Die Klassifizierung des Abgänge der fetalen Aorta gelang in 127/139 (91,4 %) der Fälle. In 103 Fällen (81,1 %) wurde ein normales Abgangsmuster beobachtet, während in 24 Fällen (18,9 %) eine Variante vorlag. In 18 Fällen wurde ein Truncus brachiocephalicus (SOGENANNTER BOVINER AORTENBOGEN),: in 4 Fällen eine aberrante linke Vertebralarterie und in einem Fall ein Aortenbogen mit fünf abgehenden Gefäßen gefunden. In einem Fall waren die Untersuc","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emilia Stegemann, Jana Larbig, Irene Portig, Nadine Weiske, Thomas Bürger, Berthold Stegemann
{"title":"Reliability of a Standardized Ultrasound Protocol for the Diagnosis of Thoracic Outlet Syndrome.","authors":"Emilia Stegemann, Jana Larbig, Irene Portig, Nadine Weiske, Thomas Bürger, Berthold Stegemann","doi":"10.1055/a-2532-4823","DOIUrl":"https://doi.org/10.1055/a-2532-4823","url":null,"abstract":"<p><p>Arterial thoracic outlet syndrome (aTOS) is a rare condition, but if undiagnosed, it can have serious consequences for affected patients, up to and including limb loss. Ultrasound could be used here as a widely available method for screening, but it is said to have very high investigator dependence. The fact that ultrasound can be used safely for diagnostic purposes has already been demonstrated. The aim of this study was to evaluate the repeatability of a standardized examination for the diagnosis of aTOS.We recruited inpatients with high-grade suspected arterial thoracic outlet syndrome who were evaluated for invasive therapy at our TOS center. Routine diagnostics were performed according to clinic standards. In addition, 2 sonographers, one highly experienced and one less experienced, performed ultrasound diagnosis according to a standardized protocol. Image acquisition and interpretation were performed independently, and sonographers were mutually blinded. For analysis, the experienced sonographer served as a reference. Agreement between assessors was analyzed using concordance analysis.51 consecutive patients (67% female) aged 39.3±13.0 years were included within 11 months. The standardized ultrasound protocol could be performed in all patients. The prevalence of TOS was high (79.4%; CI: 71.4-87.3%) in our cohort. Ultrasound inter-rater agreement using the standardized protocol was very good at 0.820 (CI: 0.624-1.000).Ultrasound diagnosis of TOS using a standardized protocol can be performed effectively and shows a high agreement between 2 sonographers.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sophie Dassen, Loes Monen, Guid Oei, Massimo Mischi, Judith van Laar
{"title":"Reply to Letter to the editor: Safety of contrast-enhanced ultrasound using microbubbles in human pregnancy: A scoping review.","authors":"Sophie Dassen, Loes Monen, Guid Oei, Massimo Mischi, Judith van Laar","doi":"10.1055/a-2479-7946","DOIUrl":"https://doi.org/10.1055/a-2479-7946","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paolo Poisa, Paolo Malerba, Anna Orsini, Linda Sabbadini, Maria Grazia De Tavonatti, Stefania Cecchinel, Paola Orizio, Stefano Caletti, Erkin Saeed Saifi, Matteo Nardin, Giovanni Pelizzari
{"title":"Diagnostic and safety value of ultrasound-guided transthoracic core needle biopsy for mediastinal masses: a single-center experience.","authors":"Paolo Poisa, Paolo Malerba, Anna Orsini, Linda Sabbadini, Maria Grazia De Tavonatti, Stefania Cecchinel, Paola Orizio, Stefano Caletti, Erkin Saeed Saifi, Matteo Nardin, Giovanni Pelizzari","doi":"10.1055/a-2511-5757","DOIUrl":"https://doi.org/10.1055/a-2511-5757","url":null,"abstract":"<p><p>US-guided (Ultrasound-guided) percutaneous transthoracic core needle biopsy (CNB) is a favorable method for establishing the correct diagnosis of mediastinal masses. However, studies in this area are scant and often include small samples, thus making it difficult to provide robust evidence regarding the safety and efficacy of this procedure. Thus, we aimed to report on the 20 years of experience at our center with regard to US-guided CNB.We included all consecutive patients referred to our center to undergo US-guided percutaneous transthoracic CNB for a mediastinal mass between 1999 and 2022. Descriptive statistics were used to display data. A multivariate logistic regression analysis was used to inquire about predictors of diagnostic sampling.The final cohort included 140 patients with a median age of 37 years. In 20.7% of the cases, the mediastinal mass was an incidental finding. The parasternal approach was used most often. US-guided CNB was diagnostic in 84.3% of the patients and most of the diagnoses included hematological neoplasms. The reasons for non-diagnostic sampling included firm lesion consistency, low quantity of samples, and lesion necrosis. The parasternal approach resulted in an independent predictor of diagnostic sampling (AOR 4.16, 95% CI 1.14-15.23, p=0.031), while a bulky feature revealed only a trend for diagnostic sampling. One non-severe adverse event occurred, with spontaneous resolution.US-guided percutaneous transthoracic CNB is an effective and safe procedure that allows the diagnosis of mediastinal masses. The identification of patients that could benefit from this technique should be the next step in researching this topic.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Timo Turowski, Martin Fleck, Boris Ehrenstein, Wolfgang Hartung, Florian Günther
{"title":"Performance of ultra-high-frequency ultrasound in the evaluation of skin atrophy in patients with long-term oral glucocorticoid therapy in a tertiary rheumatology center.","authors":"Timo Turowski, Martin Fleck, Boris Ehrenstein, Wolfgang Hartung, Florian Günther","doi":"10.1055/a-2479-8829","DOIUrl":"https://doi.org/10.1055/a-2479-8829","url":null,"abstract":"<p><p>Ultra-high-frequency ultrasound (UHF-US) allows visualization of the epidermis, dermis, and subcutis and precise measurement of skin thickness. The aim of this study was to assess the performance and interobserver reliability of UHF-US for measuring skin thickness in patients with long-term systemic glucocorticoid (GC) therapy compared to patients without GC therapy or treated for a shorter period.156 patients with known or suspected inflammatory rheumatic diseases underwent US evaluation for skin thickness by 3 experts in 3 anatomical sites (hand, distal, and proximal forearm). 87 patients were classified as \"frequent users\" who had received continuous oral GCs for at least one year or at least 3 years with various interruptions. 69 patients without any oral GC therapy in the past or treated for a shorter period were classified as \"non-frequent users\".UHF-US allowed a precise measurement of skin thickness. Skin thickness at all 3 anatomical sites was significantly decreased in \"frequent users\" of GCs compared to \"non-frequent users\" (distal and proximal forearm: p < 0.001; hand: p < 0.05). At all 3 anatomical sites, skin thickness was decreased in patients with clinically assessed parchment-like skin compared to patients without parchment-like skin (distal and proximal forearm: p < 0.001; hand: p < 0.05). Interobserver variability was excellent [hand intraclass correlation coefficient (ICC) = 0.99; proximal forearm ICC = 0.85; distal forearm ICC = 0.84].These data support the idea of UHF-US as an objective and reliable imaging tool for monitoring skin atrophy as adverse effects of GC therapy.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Swoboda, Johannes Deeg, Daniel Egle, Valentin Ladenhauf, Malik Galijasevic, Christoph Plöbst, Silke Haushammer, Birgit Amort, Mathias Pamminger, Leonhard Gruber
{"title":"Identification of differentiating sonographic features between fibroadenomas and malignant tumors of the breast mimicking fibroadenomas: 10-year experience in 421 histologically verified cases.","authors":"Michael Swoboda, Johannes Deeg, Daniel Egle, Valentin Ladenhauf, Malik Galijasevic, Christoph Plöbst, Silke Haushammer, Birgit Amort, Mathias Pamminger, Leonhard Gruber","doi":"10.1055/a-2474-6617","DOIUrl":"https://doi.org/10.1055/a-2474-6617","url":null,"abstract":"<p><p>Ultrasound is a highly effective imaging tool for assessing abnormalities within the breast. However, especially the identification of malignant tumors of the breast mimicking fibroadenomas (MTMF) by means of breast ultrasound can be challenging. This study aimed to identify reliable imaging characteristics of MTMF.This retrospective study was approved by the local ethics review board. After screening 623 patients, 421 cases with histologically verified fibroadenomas and MTMF between 2011 and 2021 were included. Sonographic features were compared to histopathological results and an algorithm-based quantitative ranking of predictors contributing most to the correct classification of malignant tumors was conducted.A total of 363 benign, 18 intermediate, and 40 malignant lesions were analyzed. Algorithm-based quantitative ranking showed that the most predictive features indicating malignancy were a hyperechoic rim (gain ratio merit 0.135 ± 0.004), an irregular border (0.057 ± 0.002), perilesional stiffening (0.054 ± 0.002), pectoral contact (0.051 ± 0.003), an irregular shape (0.029 ± 0.001), and irregular vasculature (0.027 ± 0.002).Ultrasound findings for fibroadenomas vary, making identification of MTMF challenging. Features such as indistinct margins and increased perilesional echogenicity are predictors for malignancy and should be considered during sonographic evaluation of fibroadenomas and MTMF.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V Cantisani, C F Dietrich, C Jenssen, M Bertolotto, B Brkljačić, A De Silvestri, V Scotti
{"title":"MPUS is a big step forward for small organs.","authors":"V Cantisani, C F Dietrich, C Jenssen, M Bertolotto, B Brkljačić, A De Silvestri, V Scotti","doi":"10.1055/a-2464-5428","DOIUrl":"https://doi.org/10.1055/a-2464-5428","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":"46 1","pages":"8-13"},"PeriodicalIF":3.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}