Ladina Rüegg, Julia Zepf, Markus Gonser, Nicole Ochsenbein-Kölble, Ladina Vonzun
{"title":"M-sign in middle cerebral artery Doppler in twin-to-twin transfusion syndrome - A retrospective cohort study.","authors":"Ladina Rüegg, Julia Zepf, Markus Gonser, Nicole Ochsenbein-Kölble, Ladina Vonzun","doi":"10.1055/a-2549-6161","DOIUrl":"https://doi.org/10.1055/a-2549-6161","url":null,"abstract":"<p><p>In twin-to-twin transfusion syndrome (TTTS), unbalanced vascular anastomoses lead to a net transfer of fluid from the donor to the recipient. This triggers compensatory mechanisms resulting in fetal vasoconstriction. Hemodynamic modelling has shown that the appearance of a second systolic peak P2, in addition to the main systolic peak P1, in the middle cerebral artery (MCA) Doppler waveform, thus creating a systolic M-sign, may indicate increased fetal vasoconstriction. Hence, the M-sign could be expected in twins with TTTS. The Quintero staging system has been used to stage TTTS. However, TTTS does not always develop in line with the Quintero stages and/or the criteria are not always fulfilled. This study investigates whether the M-sign could be an additional TTTS criterion indicating significant imbalance between the fetuses.38 women who underwent fetoscopic laser coagulation (FLC) for TTTS were included. The MCA Doppler waveforms were retrospectively analyzed for the presence of an M-sign. We subdivided the M-signs into 2 groups: Group A: the main systolic peak P1 dominates P2, i.e., P2/P1 <1; Group B: P2 exceeds P1: P2/P1 >1.Before FLC, an M-sign was found in 17/38 (45%) pregnancies. Both twins showed M-signs in 9 pregnancies, only the recipient in 6, and only the donor in 2. In 6 (35%) fetuses, an M-sign appeared before the Quintero criteria were fulfilled. Postoperatively, M-signs disappeared in all cases.The appearance of an M-sign could be an additional marker of cardiovascular imbalance in monochorionic-diamniotic twins with developing or already present TTTS. Postoperative M-sign disappearance may indicate fetal recovery.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Esperanza Naredo, Carlos Guillén-Astete, Otto Olivas-Vergara, Raquel Largo, José Ramón Mérida-Velasco, María Del Carmen Barrio-Asensio, Cristina Vazquez-Carballo, Gabriel Herrero-Beaumont, Jacqueline Uson, Jorge Murillo-González
{"title":"Revisiting the metacarpophalangeal joint: comparison of ultrasound tissue patterns with its anatomical, histological, and immunohistochemical features.","authors":"Esperanza Naredo, Carlos Guillén-Astete, Otto Olivas-Vergara, Raquel Largo, José Ramón Mérida-Velasco, María Del Carmen Barrio-Asensio, Cristina Vazquez-Carballo, Gabriel Herrero-Beaumont, Jacqueline Uson, Jorge Murillo-González","doi":"10.1055/a-2595-9856","DOIUrl":"10.1055/a-2595-9856","url":null,"abstract":"<p><p>This study aimed to identify the structures and tissues of the dorsal aspect of the metacarpophalangeal joint (MCPJ) using ultrasound, with gross anatomy as a comparator and learning source. In addition, the composition of several MCPJ tissues was investigated by histology and immunohistochemistry.The study comprised 3 steps. First, 4 rheumatologist ultrasonographers identified on B-mode imaging the tissue patterns of the structures in the dorsal aspect of the MCPJ in fresh-frozen cadaveric hands. In the second step, 2 anatomists performed dissections on fresh-frozen and embalmed cadaveric hands to characterize the components of the dorsal MCPJ, providing anatomy-based feedback to aid ultrasound tissue interpretation. Histological and immunohistochemical analyses were also conducted on selected dorsal MCPJ tissues. In the third step, the anatomy and histology-based knowledge were applied to identify and evaluate these structures in healthy subjects using B-mode and Doppler mode ultrasound.Ultrasound examination of the cadaveric hands identified the key dorsal MCPJ structures, including the extensor tendon, joint capsule, dorsal plate, synovial recesses, and metacarpal head cartilage. Anatomical and histological analyses further characterized these structures, enhancing their identification in healthy subjects. Additionally, new insight into the histological and immunohistological features of these structures is provided.Ultrasound successfully identified the main structures of the dorsal MCPJ. Integrating anatomical and histological features improved ultrasound imaging observations and confidence.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabella Fabietti, Chiara Vassallo, Milena Viggiano, Anna Claudia Massolo, Laura Valfrè, Alessia Sala, Lorenza Driul, Pietro Bagolan, Leonardo Caforio, Francesco Morini
{"title":"Strong heart, fit brain. Cardiac impact on brain development in fetuses with congenital diaphragmatic hernia: a prospective cohort study.","authors":"Isabella Fabietti, Chiara Vassallo, Milena Viggiano, Anna Claudia Massolo, Laura Valfrè, Alessia Sala, Lorenza Driul, Pietro Bagolan, Leonardo Caforio, Francesco Morini","doi":"10.1055/a-2618-3187","DOIUrl":"https://doi.org/10.1055/a-2618-3187","url":null,"abstract":"<p><p>Purpose CDH fetuses may present with abnormal brain volume and cerebral fissures. Since cardiac function and size may also be altered, we hypothesized that abnormal cardiac function may contribute in their impaired brain development. The aim of this study is to evaluate if cardiac dimensions and function correlate with brain development in CDH fetuses. Materials and Methods All fetuses with left CDH who underwent ultrasound evaluation of cardiac function and brain development between 2018 and 2023 were included. We analyzed the correlation between cardiac size and function parameters with the parieto-occipital (POF) and Sylvian (SF) fissures and insular depth (ID) at two gestation periods (GP). Cardiac and brain anatomical measures were corrected for head circumference, cardiac function parameters were corrected for estimated fetal weight or GA. Correlations were analyzed using Pearson test, p value <0.05 was considered significant. Results 24 fetuses with left CDH were included. Between 20 and 24 weeks gestation, POF, SF, and ID were significantly correlated with aortic flow. Right ventricle E/A was significantly correlated with POF and SF, with a trend toward correlation with ID, approaching the threshold of significance. In this GP, ID was also significantly correlated to the Left ventricle area, E/A, and E', S' and A'. Most correlations were lost in next GP. Conclusions Between 20 and 24 weeks gestation, brain development of fetuses with CDH is significantly correlated with cardiac function. Most of these correlations were lost at 25-28 weeks' gestation. Further studies are needed to confirm our results and to evaluate if these findings have postnatal clinical significance.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Elshimy, Ghada Elshimy, Ahmed Mohamed Abouelhoda, Ahmed Abdellatif Awad, Omar Farouk
{"title":"Significance of high-resolution ultrasound imaging and elastography as early predictors of diabetic peripheral neuropathy.","authors":"Ahmed Elshimy, Ghada Elshimy, Ahmed Mohamed Abouelhoda, Ahmed Abdellatif Awad, Omar Farouk","doi":"10.1055/a-2589-8675","DOIUrl":"https://doi.org/10.1055/a-2589-8675","url":null,"abstract":"<p><p>To evaluate the significance of high-resolution ultrasound (HRUS) and shear wave elastography (SWE) in the diagnosis of diabetic peripheral neuropathy (DPN) to clarify their possible roles as early predictors of the occurrence of this important complication.The study included 90 patients with diabetes mellitus with different clinical stages of DPN as well as 30 healthy controls. A full history, clinical examination, and assessment of both the Toronto Clinical Neuropathy Score (TCNS) and HbA<sub>1c</sub> were performed, followed by real-time HRUS and SWE examinations of their right and left tibial and median nerves to assess their cross-sectional area (CSA) and nerve stiffness, respectively.The CSA and stiffness of tibial and median nerves were significantly increased in patients with diabetes compared to controls, with higher values associated with the severity of their DPN. Both parameters were correlated with each other and with the duration of the disease, TCNS, and HbA<sub>1c</sub>. The CSA cut-off value of both tibial and median nerves to detect DPN in patients was 13.5 mm<sup>2</sup>, meanwhile, the SWE cut-off values were 68.5 and 61.5 KPa, respectively. SWE showed a higher AUC than CSA for the prediction of DPN.Measurement of the CSA and stiffness of the peripheral nerves could be a reliable tool for early detection of DPN. Therefore, we recommend adding these noninvasive diagnostic parameters as complementary diagnostic tools to the routine follow-up schedule of diabetic complications, especially in long-standing cases.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fetal Cerebral Ventricular Asymmetry Without Dilation: A Systematic Review.","authors":"Inshirah Sgayer, Nizar Khatib, Lior Lowenstein, Marwan Odeh","doi":"10.1055/a-2548-6131","DOIUrl":"https://doi.org/10.1055/a-2548-6131","url":null,"abstract":"<p><p>The aim of this systematic review was to investigate the outcomes of pregnancies with fetal cerebral lateral ventricle asymmetry without dilation. We conducted a comprehensive literature search in the Embase, Medline, and Web of Science databases until April 29, 2024, of observational cohort studies that reported fetal ventricular asymmetry without dilation detected on ultrasound or magnetic resonance imaging. Of the 150 studies identified, 6 met the inclusion criteria. Among the cases of non-dilated ventricular asymmetry, 36.8-46.2% progressed to ventriculomegaly on follow-up by neurosonography or magnetic resonance imaging. Additional findings in the central nervous system were observed in 5.5-10.5% of cases, while 7.6% had additional fetal body findings. Abnormal genetic findings were present in 5.1% of cases. Postnatal follow-up indicated no abnormal developmental findings during the first year of life. By the age of 9-11 years, lower writing speed was observed, yet verbal fluency scores were higher than in the general population. In conclusion, non-dilated ventricular asymmetry in fetuses showed the potential for progression to ventriculomegaly, and linkage to genetic abnormalities. Larger prospective studies are essential to fully elucidate the condition's natural history and refine clinical management strategies.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenyue Cao, Cui Chen, Lan Ma, Xiaoyi Xie, Shulian Gu, Lili Du, Lan He, Yi Yu
{"title":"Multimodality Imaging Assessment of Rosai-Dorfman Disease:A Case Report.","authors":"Wenyue Cao, Cui Chen, Lan Ma, Xiaoyi Xie, Shulian Gu, Lili Du, Lan He, Yi Yu","doi":"10.1055/a-2592-1053","DOIUrl":"https://doi.org/10.1055/a-2592-1053","url":null,"abstract":"<p><p>n/a.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camilla Aakjær Andersen, Thomas Løkkegaard, Leizl Joy Nayahangan, Hazel Edwards, Mihai Sorin Iacob, Kristina Lebedevaite, Mateusz Kosiak, Elena Codruta Gheorghe, Adib Salim, Viktor Rüttermann, Caroline Ewertsen, Christian Jenssen
{"title":"A core curriculum of point-of-care ultrasound examinations for frontline physicians in primary care: results from a European Delphi study.","authors":"Camilla Aakjær Andersen, Thomas Løkkegaard, Leizl Joy Nayahangan, Hazel Edwards, Mihai Sorin Iacob, Kristina Lebedevaite, Mateusz Kosiak, Elena Codruta Gheorghe, Adib Salim, Viktor Rüttermann, Caroline Ewertsen, Christian Jenssen","doi":"10.1055/a-2590-5242","DOIUrl":"https://doi.org/10.1055/a-2590-5242","url":null,"abstract":"<p><p>Point-of-care ultrasound (PoCUS) has found its way into primary care in some, but not all, European countries. A prerequisite for reliable and Europe-wide comparable diagnostic reliability of PoCUS performed by primary care physicians is high-quality training limited to relevant, frequently encountered PoCUS applications that are easy to learn and master. A European Federation of Societies for Ultrasound in Medicine (EFSUMB) task force commenced with a brainstorming exercise to identify all possible ultrasound examinations that could be performed in primary care. A three-stage Delphi process was launched. Delphi panellists were 95 primary care physicians from 28 European countries with more than two years of experience using and teaching ultrasound. Solely focusing on the complexity of performing PoCUS, panellists stepwise reduced the brainstorming list to a basic core curriculum intended for primary care frontline physicians including 40 diagnostic PoCUS examinations within 13 different anatomical areas and no ultrasound-guided procedures. A 75% cut-off was used for agreement. Despite the great heterogeneity of the Delphi panel representing different views and contexts from across Europe, kappa statistics showed substantial or moderate agreement across Delphi round two and three for 85% of the 40 diagnostic PoCUS applications. The results of this study offer guidance for EFSUMB to establish training recommendations for the basic core curriculum that can be adapted to the needs of different regions of Europe and thus create a basis for PoCUS to become a reliable diagnostic service in primary care across Europe, based on common quality standards.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nan Bao, Shiying Chen, Meng Dong, Guangyu Zhu, Hong Li, Xinlu Wang
{"title":"Quantitative Cystocele Assessment in Clinical Pelvic Floor Ultrasound Diagnosis.","authors":"Nan Bao, Shiying Chen, Meng Dong, Guangyu Zhu, Hong Li, Xinlu Wang","doi":"10.1055/a-2589-7938","DOIUrl":"https://doi.org/10.1055/a-2589-7938","url":null,"abstract":"<p><strong>Purpose: </strong>Cystocele is a pelvic floor dysfunction disease prone to occur in women after childbirth. As the most commonly used examination method, the accuracy of pelvic floor ultrasound diagnosis is influenced by subjective factors such as doctor experience and fatigue level, making it challenging to achieve high accuracy, consistency, and repeatability of diagnosis. This study aims to propose a high-precision and fully automatic cystocele evaluation method based on pelvic floor ultrasound video images.</p><p><strong>Materials and methods: </strong>This study retrospectively collected pelvic floor ultrasound images of 158 female G1P1 (first gestation and first parturition) patients from 2020 to 2024. According to the the ultrasound diagnosis of two senior doctors as the standard, 81 cystoceles and 66 non-cystocele patients were enrolled. Firstly, the ResNet34-UNet was used for automatic urethra segmentation. Then, key points were generated based on the automatically extracted urethra centerline. Features such as urethral key point displacement, urethral curvature change, and urethral inclination angles and their change were extracted for patients between rest and maximum Valsalva states. The support vector machine (SVM) classification model was used for cystocele prediction.</p><p><strong>Results: </strong>This study constructed two classification models to predict cystocele. One extracted the above features based on the automatic urethra segmention, while the other extracted them based on the doctor-annotated urethra. The experimental results show that both models have achieved good prediction results, with AUCs of 91.37% and 98.58%, respectively. Model performance based on the urethral image delineated by the doctor is better, with an AUC improvement of 7.21% on the independent test set.</p><p><strong>Conclusion: </strong>The proposed method can achieve high-precision, repeatable, fully automatic quantitative cystocele evaluation in pelvic floor ultrasound examinations.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriel Eisenkolb, Chiara Lecce, Nina Draeger, Anne Karge, Silvia M Lobmaier, Kathrin Abel, Eva Ostermayer, Bettina Kuschel, Javier U Ortiz, Oliver Graupner
{"title":"Value of cerebroplacental ratio in predicting adverse perinatal outcome in uncomplicated twin pregnancies: a retrospective study.","authors":"Gabriel Eisenkolb, Chiara Lecce, Nina Draeger, Anne Karge, Silvia M Lobmaier, Kathrin Abel, Eva Ostermayer, Bettina Kuschel, Javier U Ortiz, Oliver Graupner","doi":"10.1055/a-2566-8912","DOIUrl":"https://doi.org/10.1055/a-2566-8912","url":null,"abstract":"<p><p>To evaluate the performance of the cerebroplacental ratio (CPR) in predicting operative delivery for intrapartum fetal compromise (OD for IFC) and adverse perinatal outcomes in uncomplicated twin pregnancies with attempted vaginal delivery.This was a retrospective cohort study of 72 twin pregnancies in a single tertiary referral center between January 2018 and August 2024. All MCDA and DCDA twin pregnancies with an attempted vaginal delivery after 34+0 weeks were screened for eligibility and those without further risk factors were included in the study. Outcome parameters were OD for IFC and a composite of adverse perinatal outcomes (CAPO) including OD for IFC, 5-minute Apgar score <7, umbilical artery pH <7.10, or admission to the neonatal intensive care unit (NICU). The predictive performance of CPR was evaluated using ROC analyses and multivariable logistic regression.16 MCDA and 56 DCDA pregnancies met the inclusion criteria. CAPO of at least one of the twins occurred in 27 (37.5%) of the cases. ROC analyses showed that low CPR MoM of neither the presenting twin nor the second twin predicted CAPO. Similarly, the prediction of the need for OD for IFC of twin 2 was not possible using low CPR MoM as the predicting variable. However, logistic regression analyses showed that nulliparity and twin-to-twin delivery time interval were independently associated with CAPO.Low CPR MoM was not predictive for CAPO or OD for IFC in uncomplicated twin pregnancies after 34 weeks of gestation. However, nulliparity and twin-to-twin delivery time interval were independently associated with CAPO.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stine Maya Dreier Carstensen, Lawrence Grierson, Lars Konge, Søren Andreas Just, Mogens Pfeiffer-Jensen, Mikkel Ostergaard, Ingrid Möller, Maribel Miguel, Luis Coronel, David Bong, Lene Terslev
{"title":"Expert learning in musculoskeletal ultrasound - an international observational study.","authors":"Stine Maya Dreier Carstensen, Lawrence Grierson, Lars Konge, Søren Andreas Just, Mogens Pfeiffer-Jensen, Mikkel Ostergaard, Ingrid Möller, Maribel Miguel, Luis Coronel, David Bong, Lene Terslev","doi":"10.1055/a-2532-6860","DOIUrl":"https://doi.org/10.1055/a-2532-6860","url":null,"abstract":"<p><p>To examine the effect of discovery learning on musculoskeletal ultrasound (MSUS) performance and to explore how expert learners engage in a collaborative learning environment.Experts in MSUS participated in a discovery learning session where they were divided into groups. Each participant had one attempt to solve the same MSUS case and could seek assistance from other group members or learning resources. The video-recorded sessions were analyzed using both quantitative and qualitative methods. Performance was assessed using the validated Objective Structured Assessment of Ultrasound Skills (OSAUS) tool (1-5 points per item), and an outcome score was calculated based on the number of correct MSUS images (0-4). Participants' comfort and perception of discovery learning were evaluated using a 5-point Likert scale questionnaire.28 MSUS experts from 13 different countries completed the study. The mean OSAUS score (standard deviation) was 3.96 (0.5), and the mean outcome score was 1.89 (0.9). Using Pearson's correlation coefficient, we found a significant correlation between the OSAUS score and the outcome score (0.72, p < .001). The qualitative analysis revealed that the experts used actions associated with adaptive expertise and that social hierarchy persisted in the collaborative learning environment. Finally, we found high comfort with and acceptance of the discovery learning approach.Discovery learning may be an effective teaching strategy for future advanced MSUS courses, including international Teach-the-Teachers courses. Since social hierarchy was present, a facilitator is necessary during collaborative training.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}