Ultraschall in Der Medizin最新文献

{"title":"Revisiting the metacarpophalangeal joint: comparison of ultrasound tissue patterns with its anatomical, histological, and immunohistochemical features.","authors":"Esperanza Naredo, Carlos Guillén-Astete, Otto Olivas-Vergara, Raquel Largo, José Ramón Mérida-Velasco, María Del Carmen Barrio-Asensio, Cristina Vazquez-Carballo, Gabriel Herrero-Beaumont, Jacqueline Uson, Jorge Murillo-González","doi":"10.1055/a-2595-9856","DOIUrl":"10.1055/a-2595-9856","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to identify the structures and tissues of the dorsal aspect of the metacarpophalangeal joint (MCPJ) using ultrasound, with gross anatomy as a comparator and learning source. In addition, the composition of several MCPJ tissues was investigated by histology and immunohistochemistry.</p><p><strong>Materials and methods: </strong>The study comprised 3 steps. First, 4 rheumatologist ultrasonographers identified on B-mode imaging the tissue patterns of the structures in the dorsal aspect of the MCPJ in fresh-frozen cadaveric hands. In the second step, 2 anatomists performed dissections on fresh-frozen and embalmed cadaveric hands to characterize the components of the dorsal MCPJ, providing anatomy-based feedback to aid ultrasound tissue interpretation. Histological and immunohistochemical analyses were also conducted on selected dorsal MCPJ tissues. In the third step, the anatomy and histology-based knowledge were applied to identify and evaluate these structures in healthy subjects using B-mode and Doppler mode ultrasound.</p><p><strong>Results: </strong>Ultrasound examination of the cadaveric hands identified the key dorsal MCPJ structures, including the extensor tendon, joint capsule, dorsal plate, synovial recesses, and metacarpal head cartilage. Anatomical and histological analyses further characterized these structures, enhancing their identification in healthy subjects. Additionally, new insight into the histological and immunohistological features of these structures is provided.</p><p><strong>Conclusion: </strong>Ultrasound successfully identified the main structures of the dorsal MCPJ. Integrating anatomical and histological features improved ultrasound imaging observations and confidence.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"483-492"},"PeriodicalIF":3.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast-enhanced super-resolution imaging of the liver.","authors":"Ernst-Michael Jung, Irmgard Sieber, D A Clevert","doi":"10.1055/a-2917-7232","DOIUrl":"10.1055/a-2917-7232","url":null,"abstract":"<p><strong>Abstract: </strong>The present review of the most common liver lesions describes the possibilities for using the novel super-resolution contrast-enhanced ultrasound technique. There are advantages for visualizing the microvasculature and thus for the characterization of a vascular pattern: in the arterial phase as benign and regular or as malignant and irregular. In the case of hepatocellular carcinomas, small irregular focal lesions or signs of remaining tumor or early tumor recurrence after partial tumor resection or ablation can be identified. Benign tumors usually have a regular vascular pattern. Especially in the case of focal nodular hyperplasia (FNH), the regular vascular pattern can be clearly visualized on super-resolution imaging. In the case of malignant lesions, the technique can show the irregular neovascularization. The case studies relate to the most common liver lesion entities that can be detected and characterized in large clinical studies with high diagnostic certainty with dynamic contrast-enhanced ultrasound (CEUS).</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"442-472"},"PeriodicalIF":3.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the Letter to Editor (The Role of Ultrasound in Gynecomastia).","authors":"Dana I Stoian, Andreea Bena, Octavian Neagoe","doi":"10.1055/a-2947-6464","DOIUrl":"https://doi.org/10.1055/a-2947-6464","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensing ultrasound localization microscopy for ultrastructural and functional imaging of neonatal kidneys.","authors":"Henriette Grieshaber-Bouyer Mandelbaum, Felix Wachter, Louise Denis, Chiara Reisinger, Adrian Buehler, Jipeng Yan, Alina C Hilger, Tilman Jobst-Schwan, Steven Hebert, Patrick Morhart, Jörg Jüngert, Olivier Couture, Mario Schiffer, Joachim Woelfle, Heiko Reutter, Ferdinand Knieling, Gregor Hanslik, Adrian P Regensburger","doi":"10.1055/a-2700-9184","DOIUrl":"10.1055/a-2700-9184","url":null,"abstract":"<p><strong>Purpose: </strong>Sensing ultrasound localization microscopy (sULM) enables radiation-free imaging of microvascular architecture and blood flow dynamics by tracking intravasal microbubble contrast agents. This technical development aims to enable the visualization of glomeruli in the renal cortex of neonates serving as a potential imaging biopsy.</p><p><strong>Materials and methods: </strong>This technical report describes the first use of sULM in the human neonatal kidney. Neonatal subjects were examined by transabdominal contrast-enhanced ultrasound using a standard clinical ultrasound device. An image-based motion correction algorithm was implemented and the filtering, localization, and tracking of microbubbles during sULM analysis were refined. sULM algorithms were applied next to depict fast- and slow-moving microbubbles separately and to identify glomeruli by distance metric calculations.</p><p><strong>Results: </strong>Five neonates were investigated. Slow-moving microbubbles were detected mainly in the cortical region, travelling a typical route through a glomerulus. By calculating the cumulative movement of every microbubble, the number of glomeruli could be counted over the entire organ.</p><p><strong>Conclusion: </strong>We report an effective sULM workflow within the human neonate and the first microvascular sULM maps of neonatal renal vascularity up to the scale of a single glomerulus. The assessment of glomeruli as smallest functional units over the whole kidney has high potential to serve as a non-invasive imaging biomarker in future studies.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"512-520"},"PeriodicalIF":3.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145356482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point-of-care ultrasound in primary care - EFSUMB core curriculum and training recommendations - a position paper.","authors":"Camilla Aakjær Andersen, Christian Jenssen, Aaron Poppleton, Eva Leceaga, Mateusz Kosiak, Mihai Sorin Iacob, Mariela Skendi, Thomas Frese, Thomas Løkkegaard, Vesna Homar, Viktor Rüttermann, Caroline Ewertsen","doi":"10.1055/a-2771-2848","DOIUrl":"10.1055/a-2771-2848","url":null,"abstract":"<p><strong>Abstract: </strong>Frontline physicians working in primary care increasingly use diagnostic ultrasound examinations and simple ultrasound-guided procedures as part of their daily practice. Primary care is organized in many ways across Europe and as a result, primary care physicians have different qualifications in terms of using and integrating point-of-care ultrasound in patient care. To ensure high quality and standardized practice across Europe, this position paper of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) describes training recommendations and a generic core curriculum for frontline physicians working in primary care. The core curriculum was developed through a Delphi process and includes basic ultrasound examinations corresponding to the EFSUMB competence level 1 for medical ultrasound practice. The training recommendations are intended to build a common foundation while national adjustments must be made to ensure relevance in the clinical setting and patient population.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"473-482"},"PeriodicalIF":3.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13652634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medial Plantar Proper Digital Nerve Thickening - a Sonographic Finding in Volunteers Without Joplin's Neuroma.","authors":"Veronika Vetchy, Tobias Rossmann, Paata Pruidze, Wolfgang Grisold, Wolfgang Weninger, Stefan Meng","doi":"10.1055/a-2675-5871","DOIUrl":"10.1055/a-2675-5871","url":null,"abstract":"<p><strong>Purpose: </strong>Thickening of the medial plantar proper digital nerve (MPPDN) along the medial aspect of the big toe is frequently observed incidentally during high-resolution ultrasound examinations in asymptomatic individuals. However, the clinical significance of these findings remains unclear, as no study has definitively linked them to symptoms. Although the localization and visualization of the medial plantar nerve using ultrasound have been documented, its cross-sectional area has not yet been utilized to assess thickening at this specific site. The study aimed to assess the frequency and specific locations of MPPDN thickening in asymptomatic individuals and to identify associated characteristics.</p><p><strong>Materials & methods: </strong>In this prospective study, high-resolution ultrasound examination of the MPPDN was performed on asymptomatic volunteers. The cross-sectional areas and their changes along the course of the nerve are evaluated descriptively. Potential contributing demographic factors in participants are captured.</p><p><strong>Results: </strong>56 asymptomatic volunteers, 30 women and 26 men (median age: 28, range: 20-69) participated in this study. 22 individuals (39.3%) showed thickening of the MPPDN at the interphalangeal joint either in one or both feet. More participants above the median population age of 28 showed thickening of the MPPDN (15 [57.7%] versus 7 [23.3%] p = 0.009).</p><p><strong>Conclusion: </strong>Thickening of the MPPDN is frequently observed in asymptomatic individuals, with the likelihood of these findings increasing with age. The pathological significance should however not be overestimated and should be assessed in a clinical context.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"499-504"},"PeriodicalIF":3.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13652633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145985680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refining the Sonographic Stratagem in Gynecomastia.","authors":"Ilker Sengul, Demet Sengul","doi":"10.1055/a-2947-6392","DOIUrl":"https://doi.org/10.1055/a-2947-6392","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative ultrasound detection of arteria lusoria and non-recurrent laryngeal nerve anatomical variation: a retrospective study.","authors":"Jean-Baptiste Safa, Marc Tassart, Jean-Noel Talbot, Pierre-Yves Marcy, Sophie Périé, Isabelle Thomassin-Naggara, Alexandre Faure","doi":"10.1055/a-2731-9908","DOIUrl":"10.1055/a-2731-9908","url":null,"abstract":"<p><strong>Purpose: </strong>Arteria lusoria (AL), a rare vascular variant (prevalence of 0.5-3.2%), is linked to a right non-recurrent laryngeal nerve (RNRLN), thereby increasing nerve injury risk during thyroid and parathyroid surgery. This study evaluates ultrasonography (US) for preoperative AL detection.</p><p><strong>Materials and methods: </strong>Retrospective analysis of 1406 hyperparathyroidism patients undergoing 18F-fluorocholine PET/CT with subgroup analysis in 270 patients with \"expert US\" performed on-site. An experienced senior radiologist assessed the US Y-image (brachiocephalic artery division), with low-dose CT as the standard of truth for AL confirmation.</p><p><strong>Results: </strong>18F-fluorocholine PET/CT analysis found 22 cases of AL (prevalence: 1.57%). US identified 259 Y-images, excluding AL, confirmed by CT. Five absent Y-images indicated AL, all were confirmed by CT. Six non-assessable Y-images were AL-negative on CT. US performance: sensitivity 100% (95% CI: 0.463-1), specificity 98% (95% CI: 0.95-0.99), negative predictive value (NPV) 100%, accuracy 98%.</p><p><strong>Conclusion: </strong>US Y-image assessment reliably excludes AL with an NPV of 100%, offering a non-invasive tool to reduce RNRLN injury risk in thyroid and parathyroid surgery.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"505-511"},"PeriodicalIF":3.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13652632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145369070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital Vaginal and Ultrasound Assessments and the Likelihood of Intrapartum Cesarean Delivery: A Prognostic Factor Study.","authors":"Sana Usman, Birgitte Heiberg Kahrs, Wassim Hassan, Charlotte Wilhelm-Benartzi, Kjell Åsmund Salvesen, Torbjorn Eggebo, Ben Van Calster, Christoph Lees","doi":"10.1055/a-2915-9365","DOIUrl":"10.1055/a-2915-9365","url":null,"abstract":"<p><strong>Abstract: </strong>PURPOSE: Ultrasound offers an objective method of assessing the progress of labor. We sought to examine whether repeat clinical and ultrasound assessments during labor were prognostic of the mode of delivery.</p><p><strong>Abstract: </strong>MATERIALS AND METHODS: Term nulliparous women underwent ultrasound assessment of fetal head position, head descent measured as head-perineum distance, caput succedaneum, molding, umbilical, and middle cerebral artery Doppler, as well as assessment of cervical dilatation by digital vaginal examination. Univariable and multivariable logistic regression analyses were used to investigate a prognostic model for intrapartum cesarean delivery.</p><p><strong>Abstract: </strong>RESULTS: Of 270 participants, 269 were able to be evaluated. Two hundred nineteen (81%) had repeat ultrasound and clinical assessments; intrapartum cesarean delivery was required in 79 (29%). The most important parameters to determine the likelihood of intrapartum cesarean delivery from the initial assessment were head station (adjusted odds ratio [AOR] 1.08 per mm, 95% CI 1.04-1.13, <i>p</i> < 0.0001) and cervical dilatation (AOR, 0.78 per cm, (95% CI 0.66-0.92, <i>p</i> = 0.0025). For repeat assessments, change in cervical dilatation per hour was the most important (AOR, 0.10 per cm, [95% CI 0.03-0.26, <i>p</i> < 0.0001]). Multivariable analysis of the initial assessment including gestational age, head descent, cervical dilatation, and caput succedaneum gave an area under the curve of 0.72 and 0.78 when cervical dilatation and caput succedaneum were included.</p><p><strong>Abstract: </strong>CONCLUSION: This study identifies the key parameters associated with mode of delivery during labor. Clinical assessment of cervical dilatation and ultrasound measurement of head station at the initial assessment are the most promising prognostic parameters for intrapartum cesarean delivery. Repeat assessment including change in cervical dilatation improved the prediction to a level that is potentially clinically useful.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Device-Specific Cut-Offs of Canon Aplio i800 2D Shear Wave Elastography for Advanced Fibrosis in MASLD: A Histologically Validated Study.","authors":"Wolfgang Kratzer, Andreas Binzberger, Stefan G Kauschke, Finn Dolze, Markus Werner, Thomas F E Barth, Madeleine Feller, Heike Neubauer, Eric Simon, Andreas-David Brunner, Benedikt Haggenmüller, Mark M Hänle","doi":"10.1055/a-2942-6555","DOIUrl":"https://doi.org/10.1055/a-2942-6555","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diagnostic accuracy of Canon Aplio i800 two-dimensional shear wave elastography (2D-SWE) for detecting advanced fibrosis (≥ F3) in metabolically associated steatotic liver disease (MASLD) using histology as reference, and to compare its performance with the FIB-4 index.</p><p><strong>Materials and methods: </strong>In this prospective single-center study, 49 patients with MASLD and available liver histology were included. Fibrosis staging (F0-F4) was assessed by three blinded pathologists according to Brown and Kleiner. Shear wave velocity (m/s) served as the primary elastography parameter. Diagnostic performance for ≥ F3 was assessed by ROC analysis, and clinically applicable rule-in and rule-out thresholds were determined using predefined sensitivity- and specificity-based criteria.</p><p><strong>Results: </strong>Advanced fibrosis (≥ F3) was present in 15/49 patients (30.6%). 2D-SWE demonstrated an AUROC of 0.88 (95% CI 0.78-0.96) for ≥ F3, compared with 0.84 (95% CI 0.71-0.96) for FIB-4 (p = 0.39). A threshold of 1.45 m/s (6.3 kPa) achieved 100% sensitivity and negative predictive value. A threshold of 1.85 m/s (11.0 kPa) yielded 94% specificity and 82% positive predictive value.</p><p><strong>Conclusion: </strong>Canon Aplio i800 2D-SWE provides robust and clinically applicable, device-specific non-invasive detection of advanced fibrosis in MASLD and supports implementation into guideline-based stepwise risk stratification.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149018620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}