Ultraschall in Der Medizin最新文献

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Conotruncal Anomalies of the Fetus. 胎儿锥体畸形。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-09-08 DOI: 10.1055/a-2620-4784
Ingo Gottschalk, Tina Menzel, Christoph Berg
{"title":"Conotruncal Anomalies of the Fetus.","authors":"Ingo Gottschalk, Tina Menzel, Christoph Berg","doi":"10.1055/a-2620-4784","DOIUrl":"https://doi.org/10.1055/a-2620-4784","url":null,"abstract":"<p><p>Approximately 0.8 % of all children are born with heart defects, with the prenatal incidence naturally being even higher. Among all congenital heart defects (CHD), conotruncal anomalies are the most common critical heart defects - after ventricular and atrial septal defects. Conotruncal anomalies are anomalies of the infundibulum (conus arteriosus) and great vessels (truncus arteriosus). These anomalies predominantly affect the right ventricular outflow tract and account for about 25-30 % of all CHD cases. Based on their incidence and clinical relevance, this article describes perimembranous ventricular septal defects (VSD), tetralogy of Fallot (TOF), pulmonary atresia with VSD (PAVSD), transposition of the great arteries (TGA), and the less common double outlet right ventricle (DORV) and truncus arteriosus communis (TAC). Conotruncal anomalies are usually associated with a normal 4-chamber view, so the prenatal detection rate during prenatal care tends to be low. However, because undetected conotruncal anomalies have high rates of postnatal mortality and morbidity, in accordance with internationally recommended policies, the foetal heart should always be examined systematically and segmentally in different sectional planes, including the outflow tract and in combination with the color Doppler, to achieve a higher detection rate. This article provides an overview of prenatal sonographic diagnosis of conotruncal anomalies based on extensive imaging material.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally invasive ultrasound-guided carpal tunnel release: long-term clinical outcomes. 微创超声引导下的腕管松解术:长期临床结果。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-09-08 DOI: 10.1055/a-2678-8214
Sarah Honold, Alexander Loizides, Elisabeth Skalla, Leonhard Gruber, Michaela Plaikner, Hannes Gruber
{"title":"Minimally invasive ultrasound-guided carpal tunnel release: long-term clinical outcomes.","authors":"Sarah Honold, Alexander Loizides, Elisabeth Skalla, Leonhard Gruber, Michaela Plaikner, Hannes Gruber","doi":"10.1055/a-2678-8214","DOIUrl":"10.1055/a-2678-8214","url":null,"abstract":"<p><p>In cases of severe or refractory carpal tunnel syndrome (CTS), carpal tunnel release (CTR) can be performed using open surgery, endoscopic techniques, or minimally invasive approaches under high-resolution ultrasound (HRUS) guidance. This study aimed to evaluate the long-term clinical outcomes following HRUS-guided CTR.A retrospective analysis was conducted on 302 HRUS-CTR cases. Patients who were available for a phone interview and had a minimum follow-up period of one year were assessed using the Boston Carpal Tunnel Questionnaire (BCTQ). Symptom severity and functional limitations were compared before and after the procedure.Of the 302 cases screened, 111 cases had to be excluded due to unavailability for the phone call, missing data, or death. Accordingly, 191 cases were included. The average patient age was 60.4 ± 15.5 years (range: 19 to 87 years). 126 cases (66%) were female and 65 cases (34.0%) were male. Overall, there was a significant reduction of 91.9% in CTS-related symptom severity and frequency for all items recorded in the questionnaire. Similarly, a significant reduction of 84.8% in difficulty with all self-reported daily activities was found. In addition, the procedures were performed by four physicians showing no significant differences in technical success and symptoms reduction.HRUS-CTR is a safe and effective method for the treatment of CTS, showing a statistically but mostly clinically significant reduction in symptom severity and hand discomfort, which persisted 1 year after release and should therefore be considered as an alternative approach to open or endoscopic CTR.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated breast ultrasound features associated with diagnostic performance of a multiview convolutional neural network according to the level of experience of radiologists. 根据放射科医生的经验,自动乳房超声特征与多视点卷积神经网络的诊断性能相关。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-08-19 DOI: 10.1055/a-2643-9818
Eun Jung Choi, Yi Wang, Hyemi Choi, Ji Hyun Youk, Jung Hee Byon, Seoyun Choi, Seokbum Ko, Gong Yong Jin
{"title":"Automated breast ultrasound features associated with diagnostic performance of a multiview convolutional neural network according to the level of experience of radiologists.","authors":"Eun Jung Choi, Yi Wang, Hyemi Choi, Ji Hyun Youk, Jung Hee Byon, Seoyun Choi, Seokbum Ko, Gong Yong Jin","doi":"10.1055/a-2643-9818","DOIUrl":"10.1055/a-2643-9818","url":null,"abstract":"<p><p>To investigate automated breast ultrasound (ABUS) features affecting the use of a multiview convolutional neural network (CNN) for breast lesions according to the level of experience of radiologists.A total of 656 breast lesions (152 malignant and 504 benign lesions) were included and reviewed by 6 radiologists for background echotexture, glandular tissue component (GTC), and lesion type and size without as well as with a multiview CNN. The sensitivity, specificity, and the area under the receiver operating curve (AUC) for ABUS features were compared between 2 sessions according to the level of the radiologists' experience.Radiology residents showed significant AUC improvement with the multiview CNN for mass (0.81-0.91, <i>P</i>=0.003) and non-mass lesions (0.56-0.90, <i>P</i>=0.007), all background echotextures (homogeneous-fat: 0.84-0.94, <i>P</i>=0.04; homogeneous-fibroglandular: 0.85-0.93, <i>P</i>=0.01; heterogeneous: 0.68-0.88, <i>P</i>=0.002), all GTC levels (minimal: 0.86-0.93, <i>P</i>=0.001; mild: 0.82-0.94, <i>P</i>=0.003; moderate: 0.75-0.88, <i>P</i>=0.01; marked: 0.68-0.89, <i>P</i><0.001), and lesions ≤10mm (≤5mm: 0.69-0.86, <i>P</i><0.001; 6-10mm: 0.83-0.92, <i>P</i><0.001). Breast specialists showed significant AUC improvement with the multiview CNN in heterogeneous echotexture (0.90-0.95, <i>P</i>=0.03), marked GTC (0.88-0.95, <i>P</i><0.001), and lesions ≤10mm (≤5mm: 0.89-0.93, <i>P</i>=0.02; 6-10mm: 0.95-0.98, <i>P</i>=0.01).With the multiview CNN, ABUS performance among radiology residents was improved regardless of lesion type, background echotexture, or GTC. For breast lesions smaller than 10mm, both radiology residents and breast specialists achieved better ABUS performance.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of head positioning on cerebral blood velocity in the basilar artery in neonates and young infants: A single center, retrospective analysis. 头位对新生儿和婴幼儿基底动脉血流速度的影响:单中心回顾性分析。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-08-18 DOI: 10.1055/a-2685-5506
Malin Reuting, Maren Zapke, Felix Wachter, Roman Raming, Henriette Mandelbaum, Emmanuel Nedoschill, Gregor Siebenlist, Margit Schmid, Joachim Woelfle, Adrian P Regensburger, Jörg Jüngert, Ferdinand Knieling
{"title":"Effect of head positioning on cerebral blood velocity in the basilar artery in neonates and young infants: A single center, retrospective analysis.","authors":"Malin Reuting, Maren Zapke, Felix Wachter, Roman Raming, Henriette Mandelbaum, Emmanuel Nedoschill, Gregor Siebenlist, Margit Schmid, Joachim Woelfle, Adrian P Regensburger, Jörg Jüngert, Ferdinand Knieling","doi":"10.1055/a-2685-5506","DOIUrl":"10.1055/a-2685-5506","url":null,"abstract":"<p><strong>Englisch: </strong>PURPOSE: Head rotation and subsequent hypoperfusion of the brain stem might be a possible causal factor of sudden infant death. This study aimed to determine the quantitative changes of cerebral blood flow as assessed on ultrasound (US) Doppler with respect to dependence on position and age of the subject.</p><p><strong>Material and methods: </strong>This single-center retrospective study was performed to asses US Doppler measurements on vertebral and basilar arteries of neonates and infants. After measuring peak systolic flow (Vs) and time averaged velocity (TAM) in middle supine position, each subject was positioned with head rotated to the right and left both in supine and prone position. Both vertebral arteries were measured and results were correlated to individual age at investigation.</p><p><strong>Results: </strong>A total of n=1889 subjects were analyzed. Vs was 63.0±15.3 cm/s in supine middle position and reduced after head rotation to 59.9±21.6 cm/s (P<0.0001, head rotated right) and 59.4±15.6 cm/s (P<0.0001, left). In prone position it was 58.4±14.8 cm/s (P<0.0001, head rotated right) and 58.1±15.0 cm/s (P<0.0001, left). Comparable measurements were made for TAV. There was a correlation of TAV and Vs with individual postnatal age. <b>Conclusion</b> Head rotation and different positioning of the neonate/young infant leads to lower Vs and TAV values in the basilar artery. It remains unclear if these changes may help to identify patients at risk of SIDS. Furthermore, Vs and TAV are age-depend, which should be considered in the workup of transfontanellar US Doppler investigations. <b>Abstract Deutsch</b> <b>Ziel</b> Die Kopfdrehung und die daraus resultierende Hypoperfusion des Hirnstamms könnte ein möglicher kausaler Faktor für den plötzlichen Kindstod (sudden infant death syndrome, SIDS) sein. Ziel dieser Arbeit war es, die quantitativen Veränderungen des zerebralen Blutflusses, gemessen mit Ultraschall (US) Doppler, in Abhängigkeit von Position und Alter zu bestimmen. <b>Material und Methoden</b> In dieser retrospektiven, monozentrischen Studie wurden US-Dopplermessungen an Vertebral- und Basilararterien von Säuglingen durchgeführt. Nach der Messung des systolischen Spitzenflusses (Vs) und der zeitlich gemittelten Geschwindigkeit (TAV) in mittlerer Rückenlage wurde jeder Proband mit nach rechts und links gedrehtem Kopf in Rücken- und Bauchlage geschallt. Beide Vertebralarterien wurden gemessen und die Ergebnisse mit dem individuellen Alter korreliert. <b>Ergebnisse</b> Insgesamt wurden n=1889 Probanden analysiert. Vs betrug 63.0±15.3 cm/s in mittlerer Rückenlage und verringerte sich auf 60.2±21.6 cm/s nach Kopfdrehung (P<0.0001, rechts) und 59.3±15.8 cm/s (P<0.0001, links). In Bauchlage betrug der Wert 58.4±14.9 cm/s (P<0,0001, rechts) und 58.3±17.8 cm/s (P<0.0001, links). Vergleichbare Werte wurden für TAV ermittelt. Es gab eine Korrelation von TAV und Vs mit dem Alter bei Untersuchung. <b>Schlussfolgerun","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Five Growth Charts for Identifying Small-Sized Fetuses and Their Predictive Value for Adverse Neonatal Outcomes. 五种生长图识别小尺寸胎儿的比较及其对新生儿不良结局的预测价值。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-08-15 DOI: 10.1055/a-2619-7071
Ayse Cigdem Bayrak, Erdem Fadiloglu, Betul Gungor, Fatma Caner Çabukoğlu, Shahla Gasimova, Umutcan Kayikci, Ozgur Deren
{"title":"Comparison of Five Growth Charts for Identifying Small-Sized Fetuses and Their Predictive Value for Adverse Neonatal Outcomes.","authors":"Ayse Cigdem Bayrak, Erdem Fadiloglu, Betul Gungor, Fatma Caner Çabukoğlu, Shahla Gasimova, Umutcan Kayikci, Ozgur Deren","doi":"10.1055/a-2619-7071","DOIUrl":"https://doi.org/10.1055/a-2619-7071","url":null,"abstract":"<p><p>The main goal of fetal growth monitoring is to identify fetuses at increased risk of morbidity and mortality. This study compares 5 commonly used growth charts (Hadlock, FMF, NICHD, INTERGROWTH-21<sup>st</sup>, WHO) to assess their ability to identify pregnancies below the 10<sup>th</sup> percentile and predict adverse neonatal outcomes.We retrospectively analyzed 572 singleton pregnancies with an estimated fetal weight (EFW) <10<sup>th</sup> percentile according to Hadlock, excluding multiple pregnancies or cases with maternal comorbidities. Maternal and neonatal data were collected, and EFW and birthweight percentiles were recalculated using the different growth charts. Statistical analyses assessed the association between these charts and adverse neonatal outcomes.The WHO chart classified the fewest pregnancies below the 10<sup>th</sup> percentile and showed significant differences in composite adverse outcomes between the groups (p < 0.05). Despite a lack of statistical significance, the WHO chart had better prediction for NICU admission compared to others. At the 3<sup>rd</sup> percentile cutoff, all charts showed similar results for NICU admission and adverse outcomes (p < 0.01). For severe adverse outcomes, only the WHO and FMF charts showed significant differences (p = 0.043, p = 0.029).The WHO chart showed superior performance at the 10<sup>th</sup> percentile cutoff, while all charts were comparable at the 3<sup>rd</sup> percentile. Notably, the WHO and FMF charts significantly differentiated between patients with severe composite adverse outcomes at the 3<sup>rd</sup> percentile to improve the accuracy of diagnosing and predicting neonatal outcomes in small-sized fetuses.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2D-Shear Wave Elastography Increases the Diagnostic Accuracy of the TIRADS-ACR and ATA Classification Systems in Thyroid Nodule Selection: Cytological and Histological Correlation. 二维剪切波弹性成像提高了甲状腺结节选择中 TIRADS-ACR 和 ATA 分类系统的诊断准确性:细胞学和组织学相关性。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-08-14 DOI: 10.1055/a-2551-7774
Pedro Henrique Moraes, Maria Cristina Chammas, Felipe Brasileiro Vanderlei, Marcelo Violi Schelini, Carolina De Marqui Milani, Danielle Azevedo Chacon
{"title":"2D-Shear Wave Elastography Increases the Diagnostic Accuracy of the TIRADS-ACR and ATA Classification Systems in Thyroid Nodule Selection: Cytological and Histological Correlation.","authors":"Pedro Henrique Moraes, Maria Cristina Chammas, Felipe Brasileiro Vanderlei, Marcelo Violi Schelini, Carolina De Marqui Milani, Danielle Azevedo Chacon","doi":"10.1055/a-2551-7774","DOIUrl":"10.1055/a-2551-7774","url":null,"abstract":"<p><p>The aim was to evaluate whether elastography changes the accuracy of thyroid nodule malignancy risk classification using the TI-RADS ACR and ATA systems.This was a prospective study with 191 nodules (180 patients). Nodule assessments by B-mode ultrasonography (US) and 2-dimensional shear wave elastography (2D-SWE) were compared with a) fine-needle aspiration biopsy cytological (Bethesda II) and b) post-resection histology results (Bethesda III-VI). Nodules were divided into benign and malignant. B-mode US evaluated echogenicity, composition, dimensions, contours, limits, and presence of halo and echogenic foci. Elastography classified nodules from I (completely softened) to IV (completely hard). The mean nodule deformation value (assessed in m/s and kPa), the deformation ratio between nodule and thyroid parenchyma (TDR), and the deformation ratio between nodule and pre-thyroid musculature (MDR) were calculated.The significant univariate parameters for B-mode were hypoechogenicity, halo, microcalcifications, irregular contours, and ill-defined limits. All parameters were significant for elastography. The MDR (in kPa) was the best elastographic parameter: nodules with MDRs> 1.53 exhibited a higher chance of malignancy (AUC-ROC=0.831). B-mode ACR-TIRADS had an AUC of 0.678; 95% CI: 0.596-0.760, while ATA had an AUC of 0.680; 95%: 0.597-0.763. Multivariable analysis indicated that the combination of prognostic models with any elastographic parameter increased performance. ATA classification, combined with elastogram pattern and MDR (in kPa), increased the AUC to 0.892; 95% IC: 0.845-0.939.2D-SWE can increase the accuracy of the most widespread B-mode prognostic models: TI-RADS ACR and ATA.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative Cystocele Assessment in Clinical Pelvic Floor Ultrasound Diagnosis. 临床盆底超声诊断中膀胱膨出定量评估。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-08-14 DOI: 10.1055/a-2589-7938
Nan Bao, Shiying Chen, Meng Dong, Guangyu Zhu, Hong Li, Xinlu Wang
{"title":"Quantitative Cystocele Assessment in Clinical Pelvic Floor Ultrasound Diagnosis.","authors":"Nan Bao, Shiying Chen, Meng Dong, Guangyu Zhu, Hong Li, Xinlu Wang","doi":"10.1055/a-2589-7938","DOIUrl":"10.1055/a-2589-7938","url":null,"abstract":"<p><p>Cystocele is a pelvic floor dysfunction disease to which women are prone after childbirth. The accuracy of pelvic floor ultrasound as the most commonly used examination method is influenced by subjective factors such as doctor experience and fatigue level, making it challenging to achieve high accuracy, consistency, and repeatability of diagnosis. This study aims to propose a high-precision and fully automatic cystocele evaluation method based on pelvic floor ultrasound video images.This study retrospectively collected pelvic floor ultrasound images of 158 female G1P1 (first gestation and first parturition) patients from 2020 to 2024. According to the ultrasound diagnosis made by two senior doctors as the standard, 81 cystoceles and 66 non-cystocele patients were enrolled. Firstly, the ResNet34-UNet was used for automatic urethra segmentation. Then, key points were generated based on the automatically extracted urethra centerline. Features such as urethral key point displacement, urethral curvature change, and urethral inclination angles and their change were extracted for patients between rest and maximum Valsalva states. The support vector machine (SVM) classification model was used for cystocele prediction.This study constructed two classification models to predict cystocele. One extracted the above features based on the automatic urethra segmentation, while the other extracted them based on the doctor-annotated urethra. The experimental results show that both models have achieved good prediction results, with AUCs of 91.37% and 98.58%, respectively. Model performance based on the urethral image delineated by the doctor is better, with an AUC improvement of 7.21% based on the independent test set.The proposed method can achieve high-precision, repeatable, fully automatic quantitative cystocele evaluation in pelvic floor ultrasound examinations.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UDFF and Auto pSWE accurately assess liver steatosis and fibrosis risk in obese patients with MASLD. UDFF和Auto pSWE可准确评估肥胖MASLD患者的肝脏脂肪变性和纤维化风险。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-08-07 DOI: 10.1055/a-2592-1431
Nina Dominik, Larissa Nixdorf, Michael Schwarz, Benedikt Silvester Hofer, Lukas Hartl, Lorenz Balcar, Georg Semmler, Benedikt Simbrunner, Laurenz Fritz, Laurenz Hauptmann, Mathias Jachs, Julia Jedamzik, Behrang Mozayani, Lisa Gensthaler, Daniel Moritz Felsenreich, Mattias Mandorfer, Felix Langer, Michael Trauner, Thomas Reiberger, Gerhard Prager, David Jm Bauer
{"title":"UDFF and Auto pSWE accurately assess liver steatosis and fibrosis risk in obese patients with MASLD.","authors":"Nina Dominik, Larissa Nixdorf, Michael Schwarz, Benedikt Silvester Hofer, Lukas Hartl, Lorenz Balcar, Georg Semmler, Benedikt Simbrunner, Laurenz Fritz, Laurenz Hauptmann, Mathias Jachs, Julia Jedamzik, Behrang Mozayani, Lisa Gensthaler, Daniel Moritz Felsenreich, Mattias Mandorfer, Felix Langer, Michael Trauner, Thomas Reiberger, Gerhard Prager, David Jm Bauer","doi":"10.1055/a-2592-1431","DOIUrl":"https://doi.org/10.1055/a-2592-1431","url":null,"abstract":"<p><p>Metabolic dysfunction-associated steatotic liver disease (MASLD) can progress to fibrosis and cirrhosis. Fibrosis and steatosis assessment with vibration-controlled transient elastography (VCTE) and controlled attenuation parameter (CAP) requires a dedicated device and time to obtain ≥10 reliable measurements. Auto pSWE allows for the simultaneous collection of 15 ARFI-based liver stiffness measurements (LSM) and UDFF-based steatosis assessment in a single acquisition.This prospective study included patients undergoing liver biopsy, primarily during bariatric surgery, between 11/2021-12/2023. Paired LSM by Auto pSWE/VCTE and steatosis assessments by UDFF/CAP were performed within a median of 1 day before or after biopsy.134 patients (65% women, mean age: 42.6±13.3 years) with a high prevalence of obesity (mean BMI: 42.7±10.4; MASLD etiology: 88%) were included. Liver biopsy showed significant fibrosis (≥F2) in 27% of patients and moderate steatosis (≥S2) in 51%. A single 1×15 Auto pSWE acquisition and one UDFF measurement were as accurate as the median of 5 measurements. Auto pSWE (AUC: ≥F2=0.58, ≥F3=0.96, F4=0.97) and VCTE (AUC: ≥F2=0.60, ≥F3=0.92, F4=0.93) demonstrated high accuracy for advanced fibrosis stages. UDFF (AUC: ≥S1=0.79, ≥S2=0.78, S3=0.67) and CAP showed similar diagnostic accuracy.Auto pSWE and UDFF provide accurate, noninvasive tests for advanced liver fibrosis and steatosis in MASLD, even in severely obese patients. Notably, Auto pSWE captures 15 LSM with UDFF in a single acquisition, saving time and eliminating the need for a dedicated device.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The reliability and validity of superb microvascular imaging as a potential disease activity marker in rheumatoid arthritis. 超级微血管成像作为类风湿关节炎潜在疾病活动标志物的可靠性和有效性。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-08-01 Epub Date: 2024-11-07 DOI: 10.1055/a-2463-8297
Esin Kurtulus Ozturk, Saffet Ozturk, Ayse Bahar Kelesoglu Dincer
{"title":"The reliability and validity of superb microvascular imaging as a potential disease activity marker in rheumatoid arthritis.","authors":"Esin Kurtulus Ozturk, Saffet Ozturk, Ayse Bahar Kelesoglu Dincer","doi":"10.1055/a-2463-8297","DOIUrl":"10.1055/a-2463-8297","url":null,"abstract":"<p><p>Rheumatoid arthritis (RA) is a systemic autoimmune disease of unknown etiology that causes progressive and destructive inflammation in the joints. Superb microvascular imaging (SMI) is a new ultrasound technique that allows visualization of slow blood flow in synovitis. This study aimed to report on the clinical value and utility of the SMI technique and its grading for monitoring RA by determining the correlation with clinical disease activity scores (DAS 28) and power Doppler ultrasound (PDUS).All RA patients with clinically apparent synovitis were assessed using DAS 28. Synovitis was investigated with PDUS and SMI and each joint was graded semi-quantitatively. All assessments were carried out at baseline and repeated at least at the 4-month follow-up. Correlations between scores were investigated using Spearman's correlation.60 RA patients with 552 affected joints were recruited. Clinical and sonographic scores were significantly improved at follow-up (p<0.001). SMI showed significantly more joint count and flow signal scores than clinical examination and PDUS. Moderate correlations were found between the SMI score and clinical scores (p<0.001, 0.586 for SMI score vs. DAS 28-CRP, p=0.001, 0.432 for SMI vs. DAS 28-ESR). There were also stronger correlations between the SMI score and PDUS score at both baseline and follow-up (p<0.001, r = 0.817, 0.842 respectively).SMI provides greater utility and ability to detect synovial vascularity and to monitor disease activity than PDUS. A new activity scoring system based on SMI and clinical objective findings is required to improve reliability and validity.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"388-395"},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Best Practice Guidelines - DEGUM Recommendations on Breast Ultrasound. 最佳实践指南-乳腺超声DEGUM建议。
IF 2.9 3区 医学
Ultraschall in Der Medizin Pub Date : 2025-08-01 Epub Date: 2025-01-14 DOI: 10.1055/a-2487-5111
Claudia M Vogel-Minea, Werner Bader, Jens-Uwe Blohmer, Volker Duda, Christian Eichler, Eva Fallenberg, André Farrokh, Michael Golatta, Ines Gruber, Bernhard-Joachim Hackelöer, Jörg Heil, Helmut Madjar, Ellen Marzotko, Eberhard Merz, Alexander Mundinger, Markus Müller-Schimpfle, Ralf Ohlinger, Uwe Peisker, Ruediger Schulz-Wendtland, Fritz K W Schäfer, Christine Solbach, Mathias Warm, Dirk Watermann, Sebastian Wojcinski, Markus Hahn
{"title":"Best Practice Guidelines - DEGUM Recommendations on Breast Ultrasound.","authors":"Claudia M Vogel-Minea, Werner Bader, Jens-Uwe Blohmer, Volker Duda, Christian Eichler, Eva Fallenberg, André Farrokh, Michael Golatta, Ines Gruber, Bernhard-Joachim Hackelöer, Jörg Heil, Helmut Madjar, Ellen Marzotko, Eberhard Merz, Alexander Mundinger, Markus Müller-Schimpfle, Ralf Ohlinger, Uwe Peisker, Ruediger Schulz-Wendtland, Fritz K W Schäfer, Christine Solbach, Mathias Warm, Dirk Watermann, Sebastian Wojcinski, Markus Hahn","doi":"10.1055/a-2487-5111","DOIUrl":"10.1055/a-2487-5111","url":null,"abstract":"<p><p>Breast ultrasound has been established for many years as an important method in addition to mammography for clarifying breast findings. The goal of the Best Practice Guidelines Part III of the DEGUM breast ultrasound working group is to provide colleagues working in senology with information regarding the specific medical indications for breast ultrasound in addition to the current ultrasound criteria and assessment categories published in part I and the additional and optional sonographic diagnostic methods described in part II. The value of breast ultrasound for specific indications including follow-up, evaluation of breast implants, diagnostic workup of dense breast tissue, diagnostic workup during pregnancy and lactation, and the diagnostic workup of breast findings in men is discussed. Each section after the general information section contains a description of specific pathologies, followed by a short summary and DEGUM recommendations for the particular indications. The latest S3 guidelines and AGO guidelines were taken into consideration.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"345-355"},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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