Ultraschall in Der Medizin最新文献_第4页

Understanding confounding factors allows for accurate interpretation of liver stiffness measurements by ElastQ, a novel 2D shear wave elastography technique. 了解混杂因素有助于准确解释 ElastQ（一种新型二维剪切波弹性成像技术）测量的肝脏硬度。

IF 2.9 3区医学

Ultraschall in Der Medizin Pub Date : 2025-08-01 Epub Date: 2024-08-08 DOI: 10.1055/a-2329-2801

David Jm Bauer, Annalisa De Silvestri, Laura Maiocchi, Ambra Raimondi, Ruxandra Mare, Mattias Mandorfer, Ioan Sporea, Theresa Müllner-Bucsics, Giovanna Ferraioli, Thomas Reiberger

{"title":"Understanding confounding factors allows for accurate interpretation of liver stiffness measurements by ElastQ, a novel 2D shear wave elastography technique.","authors":"David Jm Bauer, Annalisa De Silvestri, Laura Maiocchi, Ambra Raimondi, Ruxandra Mare, Mattias Mandorfer, Ioan Sporea, Theresa Müllner-Bucsics, Giovanna Ferraioli, Thomas Reiberger","doi":"10.1055/a-2329-2801","DOIUrl":"10.1055/a-2329-2801","url":null,"abstract":"Liver stiffness measurement (LSM) using vibration-controlled transient elastography (VCTE) or two-dimensional shear wave elastography (2D-SWE) is recommended to assess the risk of liver fibrosis and advanced chronic liver disease. Even though both techniques measure liver stiffness, their numerical results often diverge. Confounders and reliability criteria for 2D-SWE have not been systematically investigated.We prospectively recruited participants with paired LSM by VCTE and the novel 2D-SWE technique ElastQ (Philips) in three European tertiary centers. The following parameters were recorded: sex, age, body mass index (BMI), etiology, laboratory markers of liver damage and function, as well as cholestasis, LSM by VCTE and controlled attenuation parameter (CAP), interquartile range (IQR)/median for VCTE-LSM and ElastQ-LSM, and the skin-to-liver capsule distance.We included 840 participants: 447 (53.2%) males; median age 57.0 [IQR:19.0] years; median BMI 25.4 [6.0] kg/m2; median VCTE-LSM 7.25 [9.2] kPa; median ElastQ-LSM 6.7 [5.4] kPa. On uni- and multivariable modeling (adjusted for LSM), we found that the discrepancy increased with liver stiffness and markers of disease severity. Skin-to-liver capsule distance and BMI affected VCTE-LSM more compared to ElastQ-LSM and significantly increased the discordance between the two measurements.The discrepancy of ElastQ-LSM to VCTE-LSM increases with liver stiffness and disease severity. BMI and skin-to-liver capsule distance increase the discrepancy between VCTE- and ElastQ-LSM but affect ElastQ-LSM less. The quality criterion IQR/median ≤ 30% indicates reliable ElastQ-LSM.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"363-371"},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141908161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brainstem raphe hypoechogenicity is an independent predictor of post-stroke depression. 脑干神经节瘀血过多是脑卒中后抑郁的独立预测因素。

IF 2.9 3区医学

Ultraschall in Der Medizin Pub Date : 2025-08-01 Epub Date: 2024-06-25 DOI: 10.1055/a-2296-3484

Daniel Richter, Andreas Ebert, Lisa Mazul, Quirin Ruland, Jeyanthan Charles James, Ralf Gold, Georgios Tsivgoulis, Lina Palaiodimou, Georg Juckel, Christos Krogias

{"title":"Brainstem raphe hypoechogenicity is an independent predictor of post-stroke depression.","authors":"Daniel Richter, Andreas Ebert, Lisa Mazul, Quirin Ruland, Jeyanthan Charles James, Ralf Gold, Georgios Tsivgoulis, Lina Palaiodimou, Georg Juckel, Christos Krogias","doi":"10.1055/a-2296-3484","DOIUrl":"10.1055/a-2296-3484","url":null,"abstract":"Post-stroke depression (PSD) is a common complication after stroke and has a substantial effect on the quality of life of patients. Nevertheless, reliable individual prediction of PSD is not possible. As depressive symptoms have been associated with brainstem raphe (BR) hypoechogenicity on transcranial sonography (TCS), we aimed to explore the association of BR hypoechogenicity and the occurrence of PSD.The Prognostic Markers of Post-Stroke Depression (PROMoSD) study is a prospective, observational, single-center, investigator-initiated study that included patients with acute ischemic stroke (AIS) to investigate the presence of BR hypoechogenicity by TCS early after symptom onset. The primary outcome was the presence of PSD assessed at the three-month follow-up investigation by a blinded psychiatrist and defined according to the fifth version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V criteria).From 105 included AIS patients, 99 patients completed the study. AIS patients with a hypoechogenic BR developed a PSD at three months more frequently compared to patients with normal echogenicity (48.0% versus 4.1%, P <0.001). After adjustment for confounders (sex, mRS at follow-up, previous depressive episode), a hypoechogenic BR remained independently associated with a substantial increase in the appearance of PSD (adjusted OR: 6.371, 95%-CI: 1.181-34.362).A hypoechogenic BR is a strong and independent predictor of PSD at three months after AIS. TCS could be a routine tool to assess PSD risk in clinical practice, thereby streamlining diagnostic and therapeutic algorithms.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"356-362"},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141452033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sonography of Salivary Gland Tumors and Disorders. 唾液腺肿瘤和疾病的超声检查。

IF 2.9 3区医学

Ultraschall in Der Medizin Pub Date : 2025-08-01 Epub Date: 2025-01-17 DOI: 10.1055/a-2481-7248

Felix Johnson, Alessandro Bozzato, Naglaa Mansour, Konstantinos Mantsopoulos, Georgios Psychogios, Pamela Zengel, Benedikt Hofauer

引用次数: 0

Correction: Best Practice Guidelines - DEGUM Recommendations on Breast Ultrasound. 更正：乳腺超声最佳实践指南- DEGUM建议。

IF 2.9 3区医学

Ultraschall in Der Medizin Pub Date : 2025-08-01 Epub Date: 2025-03-26 DOI: 10.1055/a-2556-4960

Claudia M Vogel-Minea, Werner Bader, Jens-Uwe Blohmer, Volker Duda, Christian Eichler, Eva Fallenberg, André Farrokh, Michael Golatta, Ines Gruber, Bernhard-Joachim Hackelöer, Jörg Heil, Helmut Madjar, Ellen Marzotko, Eberhard Merz, Alexander Mundinger, Markus Müller-Schimpfle, Ralf Ohlinger, Uwe Peisker, Ruediger Schulz-Wendtland, Fritz K W Schäfer, Christine Solbach, Mathias Warm, Dirk Watermann, Sebastian Wojcinski, Markus Hahn

引用次数: 0

Super resolution ultrasound localization microscopy - is it ready to be incorporated into clinical practice? 超分辨率超声定位显微镜-它是否准备纳入临床实践？

IF 2.9 3区医学

Ultraschall in Der Medizin Pub Date : 2025-08-01 Epub Date: 2025-08-06 DOI: 10.1055/a-2595-7852

Adrian Lim, Meng-Xing Tang

引用次数: 0

Contrast-enhanced ultrasound features as a potential biomarker for the prediction of breast cancer recurrence. 对比增强超声波特征是预测乳腺癌复发的潜在生物标志物。

IF 2.9 3区医学

Ultraschall in Der Medizin Pub Date : 2025-08-01 Epub Date: 2024-05-27 DOI: 10.1055/a-2333-7589

Youn Joo Lee, Sung Hun Kim, Bong Joo Kang, Yun Ju Kim

{"title":"Contrast-enhanced ultrasound features as a potential biomarker for the prediction of breast cancer recurrence.","authors":"Youn Joo Lee, Sung Hun Kim, Bong Joo Kang, Yun Ju Kim","doi":"10.1055/a-2333-7589","DOIUrl":"10.1055/a-2333-7589","url":null,"abstract":"To investigate the associations between contrast-enhanced ultrasound imaging features and disease recurrence among patients with locally advanced breast cancer treated with neoadjuvant chemotherapy.In the study, pre- and post-neoadjuvant chemotherapy contrast-enhanced ultrasound images of 43 patients with breast cancer were retrospectively analysed. Post-acquisition image processing involved the placement of freehand-drawn regions of interest, followed by the generation of blood flow kinetics representing blood volume and velocity for these regions of interest. Qualitative and quantitative contrast-enhanced ultrasound parameters were compared to predict recurrence, and receiver operating characteristic analysis was used to evaluate predictive ability.Among the 43 patients, 10 (23%) exhibited disease recurrence (median [range]: 27 [4-68] months). Post-neoadjuvant chemotherapy peak enhancement, wash-in area under the curve, wash-out area under the curve, and wash-in and wash-out area under the curve (p=0.003, p=0.004, p=0.026, and p=0.014, respectively) differed between the no-recurrence and recurrence groups. The area under the receiver operating characteristic curve (0.88; 95% confidence interval: 0.75-1.00) for post-neoadjuvant chemotherapy peak enhancement was the highest among the contrast-enhanced ultrasound parameters, with a cut-off of 13.33 arbitrary units.Higher peak enhancement on post-neoadjuvant chemotherapy contrast-enhanced ultrasound images was associated with recurrence in women with locally advanced breast cancer and is a potential biomarker of tumor recurrence.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"381-387"},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of placenta and fetal lung using shear wave elastography in gestational diabetes mellitus: An innovative approach. 利用剪切波弹性成像技术评估妊娠糖尿病患者的胎盘和胎肺：一种创新方法

IF 2.9 3区医学

Ultraschall in Der Medizin Pub Date : 2025-08-01 Epub Date: 2024-05-10 DOI: 10.1055/a-2323-0941

Burak Bayraktar, Hakan Golbasi, Ibrahim Omeroglu, Ceren Golbasi, Sevim Tuncer Can, Onur Ince, Miyase Gizem Bayraktar, Mehmet Ozer, Atalay Ekin

{"title":"Evaluation of placenta and fetal lung using shear wave elastography in gestational diabetes mellitus: An innovative approach.","authors":"Burak Bayraktar, Hakan Golbasi, Ibrahim Omeroglu, Ceren Golbasi, Sevim Tuncer Can, Onur Ince, Miyase Gizem Bayraktar, Mehmet Ozer, Atalay Ekin","doi":"10.1055/a-2323-0941","DOIUrl":"10.1055/a-2323-0941","url":null,"abstract":"This study aims to investigate placental and fetal lung stiffness in pregnant women with and without gestational diabetes, considering the well-established delay in fetal lung maturation associated with gestational diabetes.This prospective cohort study was conducted at a tertiary center and included pregnant women who underwent a 75-gram oral glucose tolerance test between 24-28 weeks of gestation. Elastography measurements were performed using point shear wave elastography (pSWE).The study included 60 pregnant women diagnosed with gestational diabetes and 60 pregnant women in the control group. The SWE velocity of the peripheral placenta, central placenta, and lung was higher in the gestational diabetes group compared to the control group. Furthermore, the SWE velocity of the peripheral placenta, central placenta, and lung was higher in newborns with neonatal respiratory morbidity. Based on the ROC analysis of patients with gestational diabetes, the AUC for lung SWE velocity was 0.88 (cut-off 12.4 kPa, 95% CI: 0.77-0.99, p<0.001) with a sensitivity of 71.4% and specificity of 95.6% for predicting neonatal respiratory morbidity.Fetal placental and lung stiffness increase in fetuses of pregnant women with diabetes. Moreover, higher fetal lung stiffness during the fetal period is associated with increased neonatal respiratory morbidity.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"372-380"},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140905171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systolic rise time in neurovascular duplex sonography: an important indicator of upstream vascular stenosis. 神经血管双超声收缩期上升时间：上游血管狭窄的重要指标。

IF 2.9 3区医学

Ultraschall in Der Medizin Pub Date : 2025-07-31 DOI: 10.1055/a-2649-3400

Benjamin Würzer, Thorsten Schmelzer, Tobias Braun

引用次数: 0

A core curriculum of point-of-care ultrasound examinations for frontline physicians in primary care: results from a European Delphi study. 初级保健一线医生的护理点超声检查的核心课程：来自欧洲德尔菲研究的结果。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2025-06-04 DOI: 10.1055/a-2590-5242

Camilla Aakjær Andersen, Thomas Løkkegaard, Leizl Joy Nayahangan, Hazel Edwards, Mihai Sorin Iacob, Kristina Lebedevaite, Mateusz Kosiak, Elena Codruta Gheorghe, Adib Salim, Viktor Rüttermann, Caroline Ewertsen, Christian Jenssen

{"title":"A core curriculum of point-of-care ultrasound examinations for frontline physicians in primary care: results from a European Delphi study.","authors":"Camilla Aakjær Andersen, Thomas Løkkegaard, Leizl Joy Nayahangan, Hazel Edwards, Mihai Sorin Iacob, Kristina Lebedevaite, Mateusz Kosiak, Elena Codruta Gheorghe, Adib Salim, Viktor Rüttermann, Caroline Ewertsen, Christian Jenssen","doi":"10.1055/a-2590-5242","DOIUrl":"10.1055/a-2590-5242","url":null,"abstract":"Point-of-care ultrasound (PoCUS) has found its way into primary care in some, but not all, European countries. A prerequisite for achieving Europe-wide comparable diagnostic reliability of PoCUS performed by primary care physicians is high-quality training that is limited to relevant, frequently encountered PoCUS applications that are easy to learn and master. A European Federation of Societies for Ultrasound in Medicine (EFSUMB) task force performed a brainstorming exercise to identify all possible ultrasound examinations that could be performed in primary care. A 3-stage Delphi process was launched. The Delphi panelists were 95 primary care physicians from 28 European countries with more than 2 years of experience using and teaching ultrasound. Solely focusing on the complexity of performing PoCUS, the panelists reduced the brainstorming list in a stepwise manner to a basic core curriculum intended for primary care frontline physicians including 40 diagnostic PoCUS examinations within 13 different anatomical areas and no ultrasound-guided procedures. A 75% cut-off was used for agreement. Despite the great heterogeneity of the Delphi panel representing different views and contexts from across Europe, kappa statistics showed substantial or moderate agreement across Delphi rounds 2 and 3 for 85% of the 40 diagnostic PoCUS applications. The results of this study offer guidance for EFSUMB to establish training recommendations for a basic core curriculum that can be adapted to the needs of different regions of Europe and thus create a basis for PoCUS to become a reliable diagnostic tool in primary care across Europe, based on common quality standards.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety of contrast-enhanced ultrasound using microbubbles in human pregnancy: A scoping review. 人类妊娠使用微气泡造影剂增强超声波的安全性：范围审查。

IF 3.1 3区医学

Ultraschall in Der Medizin Pub Date : 2025-06-01 Epub Date: 2024-06-24 DOI: 10.1055/a-2351-0747

Sophie Dassen, Loes Monen, Guid Oei, Massimo Mischi, Judith van Laar

{"title":"Safety of contrast-enhanced ultrasound using microbubbles in human pregnancy: A scoping review.","authors":"Sophie Dassen, Loes Monen, Guid Oei, Massimo Mischi, Judith van Laar","doi":"10.1055/a-2351-0747","DOIUrl":"10.1055/a-2351-0747","url":null,"abstract":"Successful placentation is crucial for fetal development and maintaining a healthy pregnancy. Placental insufficiency can cause a variety of obstetric complications. Despite the many efforts to enhance diagnosing placental insufficiency, no imaging technique has proven satisfactory. A promising imaging technique is contrast-enhanced ultrasound (CEUS) using microbubbles which has proven capable of (micro)vascular imaging. Its use for placental vascularization assessment in human pregnancies remains constrained by limited evidence and safety concerns. This scoping review aims to demonstrate the safety of CEUS used in human pregnancy in the published literature to date.A systematic search using PubMed, Medline, Embase, and Cochrane databases was performed. All studies where contrast-enhanced ultrasound was used in pregnant humans were included. Studies, where there was a planned termination of pregnancy, were excluded. To assess the safety of CEUS during pregnancy, relevant outcomes were divided into the following 3 categories; fetal outcome, maternal outcome, and pregnancy and neonatal outcomes.A total of 13 articles were included, in which 256 women underwent CEUS during pregnancy. No clinically significant maternal or fetal adverse events or negative pregnancy or neonatal outcomes associated with CEUS were described.Based on our findings, we consider expanding the knowledge of this promising diagnostic technique in future larger clinical studies to be safe and relevant.","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"259-269"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12143933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0