Wenyue Cao, Cui Chen, Lan Ma, Xiaoyi Xie, Shulian Gu, Lili Du, Lan He, Yi Yu
{"title":"Multimodality Imaging Assessment of Rosai-Dorfman Disease: A Case Report.","authors":"Wenyue Cao, Cui Chen, Lan Ma, Xiaoyi Xie, Shulian Gu, Lili Du, Lan He, Yi Yu","doi":"10.1055/a-2592-1053","DOIUrl":"10.1055/a-2592-1053","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"417-419"},"PeriodicalIF":3.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13461265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vito Cantisani, Maija Radzina, Christoph F Dietrich, Christian Jenssen, Helmut Prosch, Liat Appelbaum, Richard G Barr, Kunwar S S Bhatia, Manjiri Dighe, Cosimo Durante, Daniele Fresilli, Giorgio Grani, Chris Harvey, Pintong Huang, Gordana Ivanac, Adrian Lim, Süha Süreyya Özbek, Mustafa Secil, Tobias Todsen, Pierpaolo Trimboli
{"title":"EFSUMB Guidelines on Multiparametric Ultrasound Thyroid Nodule Evaluation: PART II.","authors":"Vito Cantisani, Maija Radzina, Christoph F Dietrich, Christian Jenssen, Helmut Prosch, Liat Appelbaum, Richard G Barr, Kunwar S S Bhatia, Manjiri Dighe, Cosimo Durante, Daniele Fresilli, Giorgio Grani, Chris Harvey, Pintong Huang, Gordana Ivanac, Adrian Lim, Süha Süreyya Özbek, Mustafa Secil, Tobias Todsen, Pierpaolo Trimboli","doi":"10.1055/a-2761-1329","DOIUrl":"10.1055/a-2761-1329","url":null,"abstract":"<p><strong>Abstract: </strong>Thyroid nodules are common incidental findings but only a small proportion of cases are malignant (4-6.5%) or symptomatic. Numerous follow-up examinations and invasive diagnostic procedures, such as fine-needle aspiration, fine-needle biopsies, and thyroidectomies, are performed, leading to potentially costly and time-consuming diagnostic procedures and overtreatment. Most experts and scientific societies (EFSUMB, WFUMB, etc.) encourage the use of multiparametric ultrasound (MPUS) evaluation to improve thyroid nodule characterization due to the continuous technological developments including new ultrasound software (microvascular flow imaging, elastosonography, etc.), contrast media (CEUS), and artificial intelligence (AI). Therefore, the recognition and proper use of new multiparametric ultrasound features of thyroid nodules are essential for minimizing unnecessary interventions and guiding appropriate treatment. The goal of these guidelines is to help initiate use of these features in routine clinical practice. In addition, we analyze the use of MPUS in some emblematic thyroid scenarios, such as cytologically indeterminate nodules, multinodular goiters, and extrathyroidal extension of the malignant nodule, and the usefulness of MPUS as a guide for thyroid biopsy/aspiration and in the staging of cervical lymph nodes. Recommendations based on the level of evidence of the published literature and on the EFSUMB expert group's consensus are given for each question.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"361-370"},"PeriodicalIF":3.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nan Bao, Shiying Chen, Meng Dong, Guangyu Zhu, Hong Li, Xinlu Wang
{"title":"Quantitative Cystocele Assessment in Clinical Pelvic Floor Ultrasound Diagnosis.","authors":"Nan Bao, Shiying Chen, Meng Dong, Guangyu Zhu, Hong Li, Xinlu Wang","doi":"10.1055/a-2589-7938","DOIUrl":"10.1055/a-2589-7938","url":null,"abstract":"<p><strong>Purpose: </strong>Cystocele is a pelvic floor dysfunction disease to which women are prone after childbirth. The accuracy of pelvic floor ultrasound as the most commonly used examination method is influenced by subjective factors such as doctor experience and fatigue level, making it challenging to achieve high accuracy, consistency, and repeatability of diagnosis. This study aims to propose a high-precision and fully automatic cystocele evaluation method based on pelvic floor ultrasound video images.</p><p><strong>Materials and methods: </strong>This study retrospectively collected pelvic floor ultrasound images of 158 female G1P1 (first gestation and first parturition) patients from 2020 to 2024. According to the ultrasound diagnosis made by two senior doctors as the standard, 81 cystoceles and 66 non-cystocele patients were enrolled. Firstly, the ResNet34-UNet was used for automatic urethra segmentation. Then, key points were generated based on the automatically extracted urethra centerline. Features such as urethral key point displacement, urethral curvature change, and urethral inclination angles and their change were extracted for patients between rest and maximum Valsalva states. The support vector machine (SVM) classification model was used for cystocele prediction.</p><p><strong>Results: </strong>This study constructed two classification models to predict cystocele. One extracted the above features based on the automatic urethra segmentation, while the other extracted them based on the doctor-annotated urethra. The experimental results show that both models have achieved good prediction results, with AUCs of 91.37% and 98.58%, respectively. Model performance based on the urethral image delineated by the doctor is better, with an AUC improvement of 7.21% based on the independent test set.</p><p><strong>Conclusion: </strong>The proposed method can achieve high-precision, repeatable, fully automatic quantitative cystocele evaluation in pelvic floor ultrasound examinations.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"397-406"},"PeriodicalIF":3.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unicornuate Uterus: Ultrasound Diagnosis and Implications for Early Pregnancy.","authors":"Markus Hoopmann","doi":"10.1055/a-2876-6129","DOIUrl":"https://doi.org/10.1055/a-2876-6129","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":"47 4","pages":"324"},"PeriodicalIF":3.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Boccatonda, Cosima Schiavone, Carla Serra, Fabio Piscaglia
{"title":"Gallbladder polyps: ultrasound diagnosis, updated guidelines, and clinical management.","authors":"Andrea Boccatonda, Cosima Schiavone, Carla Serra, Fabio Piscaglia","doi":"10.1055/a-2655-8601","DOIUrl":"10.1055/a-2655-8601","url":null,"abstract":"<p><strong>Abstract: </strong>Ultrasound is a relevant tool in the diagnosis and characterization of gallbladder polyps. B-mode imaging can be used for the identification of echogenic formations attached to the gallbladder wall, while advanced techniques such as color Doppler, power Doppler, and micro-flow allow a thorough assessment of polyp vascularization. The integration of CEUS further improves diagnostic accuracy by confirming the integrity of the wall and the absence of pathological washout, which is characteristic of malignant lesions. In recent years, several guidelines have been published on the integrated clinical and ultrasound management of polypoid formations of the gallbladder. This review aims to summarize the main evidence regarding the ultrasound study of gallbladder polyps and to provide the sonographer with a clear and practical approach to the clinical management and follow-up of these patients.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"371-381"},"PeriodicalIF":3.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabella Fabietti, Chiara Vassallo, Milena Viggiano, Anna Claudia Massolo, Laura Valfrè, Alessia Sala, Lorenza Driul, Pietro Bagolan, Leonardo Caforio, Francesco Morini
{"title":"Strong heart, fit brain. Cardiac impact on brain development in fetuses with congenital diaphragmatic hernia: a prospective cohort study.","authors":"Isabella Fabietti, Chiara Vassallo, Milena Viggiano, Anna Claudia Massolo, Laura Valfrè, Alessia Sala, Lorenza Driul, Pietro Bagolan, Leonardo Caforio, Francesco Morini","doi":"10.1055/a-2618-3187","DOIUrl":"10.1055/a-2618-3187","url":null,"abstract":"<p><strong>Purpose: </strong>CDH fetuses may present with abnormal brain volume and cerebral fissures. Since cardiac function and size may also be altered, we hypothesized that abnormal cardiac function may contribute to the impaired brain development in these fetuses. The aim of this study is to evaluate whether cardiac dimensions and function correlate with brain development in CDH fetuses.</p><p><strong>Materials and methods: </strong>All fetuses with left CDH who underwent ultrasound evaluation of cardiac function and brain development between 2018 and 2023 were included. We analyzed the correlation between cardiac size and function parameters with the parieto-occipital (POF) and Sylvian (SF) fissures and insular depth (ID) in 2 gestational periods (GP). Cardiac and brain anatomical measures were corrected for head circumference, and cardiac function parameters were corrected for estimated fetal weight or GA. Correlations were analyzed using the Pearson test. A p-value <0.05 was considered significant.</p><p><strong>Results: </strong>24 fetuses with left CDH were included. Between 20 and 24 weeks of gestation, POF, SF, and ID were significantly correlated with aortic flow. Right ventricle E/A was significantly correlated with POF and SF, with a trend toward a correlation with ID, approaching the threshold of significance. In this GP, the ID was also significantly correlated with the left ventricle area, E/A, and E', S' and A'. Most correlations were lost in the next GP.</p><p><strong>Conclusion: </strong>Between 20 and 24 weeks of gestation, brain development in fetuses with CDH is significantly correlated with cardiac function. Most of these correlations were lost at 25-28 weeks of gestation. Further studies are needed to confirm our results and to evaluate whether these findings have postnatal clinical significance.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"382-388"},"PeriodicalIF":3.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound-guided spinal interventions in pain medicine.","authors":"Peter Schwarzkopf, Karsten Pracht","doi":"10.1055/a-2840-1286","DOIUrl":"10.1055/a-2840-1286","url":null,"abstract":"<p><strong>Abstract: </strong>Spinal pain interventions are traditionally performed exclusively using landmarks or fluoroscopy or computed tomography. However, ultrasound offers a radiation-free method that not only takes individual anatomy into account but also allows for highly precise infiltration. This significantly reduces intervention times and improves patient comfort.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"334-360"},"PeriodicalIF":3.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147976705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Five Growth Charts for Identifying Small-Sized Fetuses and Their Predictive Value for Adverse Neonatal Outcomes.","authors":"Ayse Cigdem Bayrak, Erdem Fadiloglu, Betul Gungor, Fatma Caner Çabukoğlu, Shahla Gasimova, Umutcan Kayikci, Ozgur Deren","doi":"10.1055/a-2619-7071","DOIUrl":"10.1055/a-2619-7071","url":null,"abstract":"<p><strong>Purpose: </strong>The main goal of fetal growth monitoring is to identify fetuses at increased risk of morbidity and mortality. This study compares 5 commonly used growth charts (Hadlock, FMF, NICHD, INTERGROWTH-21<sup>st</sup>, WHO) to assess their ability to identify pregnancies below the 10<sup>th</sup> percentile and predict adverse neonatal outcomes.</p><p><strong>Materials and methods: </strong>We retrospectively analyzed 572 singleton pregnancies with an estimated fetal weight (EFW) <10<sup>th</sup> percentile according to Hadlock, excluding multiple pregnancies or cases with maternal comorbidities. Maternal and neonatal data were collected, and EFW and birthweight percentiles were recalculated using the different growth charts. Statistical analyses assessed the association between these charts and adverse neonatal outcomes.</p><p><strong>Results: </strong>The WHO chart classified the fewest pregnancies below the 10<sup>th</sup> percentile and showed significant differences in composite adverse outcomes between the groups (p < 0.05). Despite a lack of statistical significance, the WHO chart had better prediction for NICU admission compared to others. At the 3<sup>rd</sup> percentile cutoff, all charts showed similar results for NICU admission and adverse outcomes (p < 0.01). For severe adverse outcomes, only the WHO and FMF charts showed significant differences (p = 0.043, p = 0.029).</p><p><strong>Conclusion: </strong>The WHO chart showed superior performance at the 10<sup>th</sup> percentile cutoff, while all charts were comparable at the 3<sup>rd</sup> percentile. Notably, the WHO and FMF charts significantly differentiated between patients with severe composite adverse outcomes at the 3<sup>rd</sup> percentile to improve the accuracy of diagnosing and predicting neonatal outcomes in small-sized fetuses.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"389-396"},"PeriodicalIF":3.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scaling Expertise in Endometriosis Diagnosis: Can Artificial Intelligence Close the Gap?","authors":"Michael Bajka, Markus Hoopmann","doi":"10.1055/a-2876-6072","DOIUrl":"https://doi.org/10.1055/a-2876-6072","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":"47 4","pages":"325-333"},"PeriodicalIF":3.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuela Tavares de Sousa, Fatima Crispi, Olga Gomez, Bettina Hergert, Kurt Hecher
{"title":"The carotid-subclavian artery index (CSAI) in the fetal aortic arch with classical branching and brachiobicephalic trunk in a midtrimester low risk population.","authors":"Manuela Tavares de Sousa, Fatima Crispi, Olga Gomez, Bettina Hergert, Kurt Hecher","doi":"10.1055/a-2922-1435","DOIUrl":"https://doi.org/10.1055/a-2922-1435","url":null,"abstract":"<p><p>Purpose The carotid-subclavian artery index (CSAI) has shown high sensitivity and specificity for diagnosing coarctation of the aorta (CoA) in fetuses and neonates. We investigated whether variations in aortic arch (AA) branching without CoA affect CSAI by comparing fetuses with the classical pattern to those with a brachiobicephalic trunk (BBCT), the most frequent variant. Material and Methods In this prospective cohort study of 335 low-risk singleton pregnancies (19 - 22 weeks of gestation), standardized fetal echocardiography was used to assess AA branching in a sagittal view. Two blinded observers classified branching patterns and calculated CSAI. Results Adequate image quality was obtained in 262/335 (78.2%). 194/262 (74%) fetuses showed a classical pattern and 66 (25.2%) a branching variant. Furthermore, two fetuses (0.8%) due to disagreement on branching pattern. 50/66 (76.8%) fetuses with isolated BBCT were compared with 194 cases with classical AA branching pattern. 16 other variants were excluded. Interobserver agreement showed an intraclass correlation coefficient (ICC) of 0.87 (95%CI: 0.89-0.95). Mean CSAI was significantly lower in BBCT (0.71 ± 0.14) than in classical branching (1.46 ± 0.37; P < 0.001). None required cardiac intervention within two years. Conclusions Targeted fetal echocardiography showed a lower CSAI in cases with BBCT than in classical branching pattern. Future studies are warranted to assess the diagnostic impact of our findings in the setting of suspected CoA. Zielsetzung: Der Carotis-Subclavian-Artery-Index (CSAI) wird in der Diagnostik der Aortenisthmusstenose (CoA) eingesetzt. Wir untersuchten, ob der CSAI bei Feten mit Varianten der Aortenabgänge eine Rolle spielt und verglichen diesen mit Werten bei Aortenbögen mit klassischen Abgängen. Material und Methoden: In dieser prospektiven Kohortenstudie wurden 335 Einlingsschwangerschaften mit niedrigem Risiko zwischen der 19. und 22. Schwangerschaftswoche mittels standardisierter fetaler Echokardiografie untersucht. Der Aortenbogen wurde in sagittaler Ebene dargestellt. Zwei voneinander unabhängige Untersuchende beurteilten verblindet das Abgangsmuster und berechneten den CSAIErgebnisse: Eine ausreichende Bildqualität konnte bei 262 von 335 Fällen (78,2 %) erzielt werden. 194/262 (74 %) Feten zeigten ein klassisches Abgangsmuster, 66 (25,2 %) eine Variante. Bei zwei Feten (0,8 %) bestand Uneinigkeit über das Abgangsmuster. 50/66 (76,8 %) Feten mit isoliertem BBCT wurden mit den 194 Fällen mit klassischem Abgang verglichen; 16 weitere Varianten wurden ausgeschlossen. Die Interobserver-Übereinstimmung zeigte einen Intraklassen-Korrelationskoeffizienten (ICC) von 0,87 (95 %-KI: 0,89-0,95). Der mittlere CSAI war bei BBCT signifikant niedriger (0,71 ± 0,14) als bei klassischem Abgang (1,46 ± 0,37; p < 0,001). Kein Kind benötigte innerhalb von zwei Jahren eine kardiale Intervention. Schlussfolgerung: Die gezielte fetale Echokardiografie zeigte einen signifikant ni","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148581064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}