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Low Dose Pediatric CT Head Protocol using Iterative Reconstruction Techniques: A Comparison with Standard Dose Protocol. 使用迭代重建技术的低剂量儿童CT头部方案:与标准剂量方案的比较。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2024-03-01 Epub Date: 2023-11-28 DOI: 10.1007/s00062-023-01361-4
Priyanka, Rajagopal Kadavigere, Suresh Sukumar
{"title":"Low Dose Pediatric CT Head Protocol using Iterative Reconstruction Techniques: A Comparison with Standard Dose Protocol.","authors":"Priyanka, Rajagopal Kadavigere, Suresh Sukumar","doi":"10.1007/s00062-023-01361-4","DOIUrl":"10.1007/s00062-023-01361-4","url":null,"abstract":"<p><strong>Purpose: </strong>Pediatric computed tomography (CT) head examination has also increased in recent years with the advancement in CT technology; however, children exposed to radiation at the youngest age are more vulnerable to the risks of radiation. The aim of the study is to evaluate radiation dose and image quality of low dose pediatric CT head protocol compared to standard dose pediatric CT head protocol.</p><p><strong>Methods: </strong>This was a prospective study. Group 1 included 73 patients aged < 1 year and 70 patients in the 1-5 years age group and had undergone CT head examination using the standard dose protocol. Group 2 included 31 patients aged < 1 year and 40 patients in the 1-5 years age group and had undergone CT head examination using the low dose protocol. The radiation dose was measured and image quality was assessed quantitatively and qualitatively.</p><p><strong>Results: </strong>There was a significant difference in radiation dose between the standard and low dose protocols (p > 0.05) with lower radiation dose for low dose group. The qualitative analysis did not show a significant difference between the standard and low dose protocols. The gray-white matter differentiation (GWMD), attenuation, contrast to noise ratio (CNR) and figure of merit (FOM) were higher in the low dose protocol compared to the standard dose with a significant difference (p > 0.05).</p><p><strong>Conclusion: </strong>The study concludes that a low dose protocol at 80 kV tube voltage/150 mAs tube current exposure time product/iterative reconstruction-iDose<sup>4</sup> (level 3) for < 1 year age group and 100 kV/200m As/iDose<sup>4</sup> (level 3) for 1-5 years age group provides ultra-low effective dose with diagnostically acceptable image quality for pediatric CT head examination compared with standard dose protocol.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"229-239"},"PeriodicalIF":2.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138446771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Societies' Communications. 社团通讯。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2023-12-01 DOI: 10.1007/s00062-023-01360-5
{"title":"Societies' Communications.","authors":"","doi":"10.1007/s00062-023-01360-5","DOIUrl":"10.1007/s00062-023-01360-5","url":null,"abstract":"","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"1165-1167"},"PeriodicalIF":2.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54231904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Freiburg Neuropathology Case Conference : Headache, Mental Confusion and Mild Hemiparesis in a 68-year-old Patient. 弗赖堡神经病理学病例会议:一名68岁患者的头痛、精神错乱和轻度偏瘫。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2023-12-01 Epub Date: 2023-10-23 DOI: 10.1007/s00062-023-01359-y
M Frosch, T Demerath, C Fung, M Prinz, H Urbach, D Erny, C A Taschner
{"title":"Freiburg Neuropathology Case Conference : Headache, Mental Confusion and Mild Hemiparesis in a 68-year-old Patient.","authors":"M Frosch, T Demerath, C Fung, M Prinz, H Urbach, D Erny, C A Taschner","doi":"10.1007/s00062-023-01359-y","DOIUrl":"10.1007/s00062-023-01359-y","url":null,"abstract":"","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"1159-1164"},"PeriodicalIF":2.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49693390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
58. Jahrestagung der Deutschen Gesellschaft für Neuroradiologie e.V. und 30. Jahrestagung der Österreichischen Gesellschaft für Neuroradiologie e.V. 58.德国神经放射学学会年会e.V.和30。奥地利神经放射学学会年会。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2023-09-01 DOI: 10.1007/s00062-023-01336-5
{"title":"58. Jahrestagung der Deutschen Gesellschaft für Neuroradiologie e.V. und 30. Jahrestagung der Österreichischen Gesellschaft für Neuroradiologie e.V.","authors":"","doi":"10.1007/s00062-023-01336-5","DOIUrl":"https://doi.org/10.1007/s00062-023-01336-5","url":null,"abstract":"","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"33 Suppl 1","pages":"1-140"},"PeriodicalIF":2.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41171439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comaneci plus Balloon-assisted Embolization of Ruptured Wide-necked Cerebral Aneurysms. 科马内奇+球囊辅助栓塞术治疗脑宽颈动脉瘤破裂。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-01-18 DOI: 10.1007/s00062-021-01115-0
A Sirakov, P Bhogal, S Bogovski, S Matanov, K Minkin, H Hristov, K Ninov, V Karakostov, M Penkov, S Sirakov
{"title":"Comaneci plus Balloon-assisted Embolization of Ruptured Wide-necked Cerebral Aneurysms.","authors":"A Sirakov,&nbsp;P Bhogal,&nbsp;S Bogovski,&nbsp;S Matanov,&nbsp;K Minkin,&nbsp;H Hristov,&nbsp;K Ninov,&nbsp;V Karakostov,&nbsp;M Penkov,&nbsp;S Sirakov","doi":"10.1007/s00062-021-01115-0","DOIUrl":"https://doi.org/10.1007/s00062-021-01115-0","url":null,"abstract":"<p><strong>Background and purpose: </strong>Recently, avant-garde combinations of ancillary devices as an adjunct to coil embolization for acutely ruptured and wide-necked cerebral aneurysms have emerged. This study sought to investigate the feasibility, safety and durability of the simultaneous combination of temporary neck-bridging devices plus balloon-assisted coiling (BAC) to treat acutely ruptured and wide-necked cerebral aneurysms.</p><p><strong>Methods: </strong>A retrospective review was performed of patients with ruptured and wide-necked intracranial bifurcation aneurysms treated with temporary stent plus balloon-assisted coiling. Anatomical features, technical details, intraprocedural complications, clinical and angiographic results were reviewed. Preprocedural and follow-up clinical statuses were evaluated using the modified Rankin scale (mRS).</p><p><strong>Results: </strong>A total of 21 patients (mean age 54.5 years, range 37-72 years) were identified. The immediate postprocedural angiography revealed complete aneurysm occlusion in 85.7% (18/21) of the cases. A periprocedural complication developed in 9.5% of the cases. There was no mortality in this study. The permanent morbidity rate was 4.7%. Long-term follow-up angiography was performed in 18 of 21 patients (85.7%) (the mean follow-up period was 21 months). The rate of complete aneurysm occlusion at final follow-up was 89.4%.</p><p><strong>Conclusion: </strong>The results of this study confirmed that temporary stent plus balloon-assisted coiling is a durable and relatively safe endovascular technique for the treatment of ruptured wide-necked bifurcation aneurysms located in both the posterior and anterior cerebral circulation.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"773-782"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39942962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Benefits from Exclusion Treatment of Unruptured Brain Arteriovenous Malformations on Epilepsy in Adults. 排除治疗未破裂脑动静脉畸形对成人癫痫的益处。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2021-11-22 DOI: 10.1007/s00062-021-01119-w
Romain Capocci, Michaela Bustuchina Vlaicu, Eimad Shotar, Bertrand Mathon, Mariette Delaitre, Kévin Premat, Maichael Talaat, Atika Talbi, Anne-Laure Boch, Stéphanie Lenck, Alexandre Carpentier, Vincent Degos, Nader Antoine Sourour, Frédéric Clarençon
{"title":"Benefits from Exclusion Treatment of Unruptured Brain Arteriovenous Malformations on Epilepsy in Adults.","authors":"Romain Capocci,&nbsp;Michaela Bustuchina Vlaicu,&nbsp;Eimad Shotar,&nbsp;Bertrand Mathon,&nbsp;Mariette Delaitre,&nbsp;Kévin Premat,&nbsp;Maichael Talaat,&nbsp;Atika Talbi,&nbsp;Anne-Laure Boch,&nbsp;Stéphanie Lenck,&nbsp;Alexandre Carpentier,&nbsp;Vincent Degos,&nbsp;Nader Antoine Sourour,&nbsp;Frédéric Clarençon","doi":"10.1007/s00062-021-01119-w","DOIUrl":"https://doi.org/10.1007/s00062-021-01119-w","url":null,"abstract":"<p><strong>Purpose: </strong>In approximately 30% of the patients, brain arteriovenous malformations (bAVMs) are revealed by seizures, which may alter the patients' quality of life. Our objective was to evaluate the benefits of exclusion treatment (radiosurgery, embolization and/or surgery) on posttherapeutic epilepsy in bAVM patients without intracranial hemorrhage prior to treatment.</p><p><strong>Methods: </strong>Our retrospective observational single-center study included all consecutive adult patients with an unruptured bAVM and epilepsy, treated at our institution from 1995 to 2019 and who were followed for at least 1 year. Data on angioarchitectural characteristics of bAVMs, on epilepsy and posttreatment modified Rankin Scale (mRS) were collected. The primary endpoint was a seizure-free status (defined as Engel class IA) after exclusion treatment versus conservative management.</p><p><strong>Results: </strong>In this study one hundred and one consecutive adult patients with bAVMs, epilepsy and without bAVM rupture before any treatment were included; 21 (21%) in the conservative management group vs. 80 (79%) in the exclusion treatment group. After exclusion treatment, 55% of the patients from the group were Engel IA after treatment vs. 10% of the conservative management group (odds ratio [OR] 11.37, 95% confidence interval [CI] 2.48-107.24, p < 0.001).</p><p><strong>Conclusion: </strong>Our results suggest that exclusion treatment in unruptured bAVMs with epilepsy is associated with a higher seizure-free rate in comparison with conservative management. Data from randomized controlled studies are necessary to confirm these findings.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"749-760"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39646341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Radiolucent Zone around Screws is Associated with Position Change of Screw-rod Constructs. 螺钉周围的透光区与螺杆结构的位置变化有关。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-01-10 DOI: 10.1007/s00062-021-01132-z
Satoru Tanioka, Masashi Fujimoto, Hirofumi Nishikawa, Katsuhiro Tanaka, Fujimaro Ishida, Atsushi Yamamoto, Munenari Ikezawa, Yusuke Kamei, Hidenori Suzuki, Masaki Mizuno
{"title":"Radiolucent Zone around Screws is Associated with Position Change of Screw-rod Constructs.","authors":"Satoru Tanioka,&nbsp;Masashi Fujimoto,&nbsp;Hirofumi Nishikawa,&nbsp;Katsuhiro Tanaka,&nbsp;Fujimaro Ishida,&nbsp;Atsushi Yamamoto,&nbsp;Munenari Ikezawa,&nbsp;Yusuke Kamei,&nbsp;Hidenori Suzuki,&nbsp;Masaki Mizuno","doi":"10.1007/s00062-021-01132-z","DOIUrl":"https://doi.org/10.1007/s00062-021-01132-z","url":null,"abstract":"<p><strong>Purpose: </strong>A radiologic assessment method to measure position change of screw-rod constructs over time by superposing the 3‑dimensional images assists in quantitative evaluation of screw loosening. We investigated the association between position change and radiolucent zone that was commonly used for diagnosing screw loosening.</p><p><strong>Methods: </strong>In this study 101 patients who underwent lumbar fusion were reviewed. Patient characteristics included age, sex, indications for surgery, number of fused levels, surgical procedures, and timing of follow-up computed tomography (CT, 1-5 months, 6-11 months, and ≥ 12 months). The Hounsfield unit values of L1 vertebra on preoperative CT were measured, and the radiolucent zone on each follow-up CT was evaluated. Using baseline CT on the day after surgery and follow-up CT, 3‑dimensional images of screw-rod constructs were generated and superposed. Position change was assessed by the median of the distances between the 3‑dimensional images at baseline and follow-up using the automated measurement method. Patient characteristics, the Hounsfield unit values of L1, and the amount of position change were categorized into the radiolucent zone presence and absence groups and compared.</p><p><strong>Results: </strong>The medians of position change were 0.281 mm and 0.136 mm in the radiolucent zone presence and absence groups, respectively (P < 0.001 by Mann-Whitney U-test). The area under the curve for position change in identifying radiolucent zone was 0.846; the cut-off value was 1.76 mm. In multivariable analysis, position change was independently associated with radiolucent zone (adjusted odds ratio per 0.1 mm, 2.80, 95% confidence interval 1.70-4.61).</p><p><strong>Conclusion: </strong>Radiolucent zone was associated with position change of screw-rod constructs.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"717-724"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39803045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparison of Four International Guidelines on the Utility of Cranial Imaging Before Lumbar Puncture in Adults with Bacterial Meningitis. 成人细菌性脑膜炎腰椎穿刺前颅成像的四个国际指南的比较。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-02-18 DOI: 10.1007/s00062-022-01143-4
Nicola Park, Masayuki Nigo, Rodrigo Hasbun
{"title":"Comparison of Four International Guidelines on the Utility of Cranial Imaging Before Lumbar Puncture in Adults with Bacterial Meningitis.","authors":"Nicola Park,&nbsp;Masayuki Nigo,&nbsp;Rodrigo Hasbun","doi":"10.1007/s00062-022-01143-4","DOIUrl":"https://doi.org/10.1007/s00062-022-01143-4","url":null,"abstract":"<p><strong>Background: </strong>International guidelines exist for obtaining a head computed tomography (CT) scan before a lumbar puncture (LP) in adults with suspected meningitis but there are no studies comparing them in their ability to identify intracranial abnormalities.</p><p><strong>Methods: </strong>A retrospective study of 202 cases of adults with community-acquired bacterial meningitis at 16 hospitals in Houston from December 2004 until May 2019 to compare the 4 guidelines' ability in identifying minor and major intracranial findings, cases in which CT findings changed management, and patients who suffered cerebral herniation.</p><p><strong>Results: </strong>Minor and major intracranial findings were seen in 69 (34.1%) and in 24 (11.8%) of the patients, respectively. A total of nine (37.5%) of the major intracranial findings prompted a neurosurgical intervention. A total of four (1.9%) patients had cerebral herniation. The Infectious Diseases of America (IDSA), the United Kingdom (UK), the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), and the Swedish guidelines for cranial imaging were met in 92.1%, 54%, 41.6%, and in 23.3% of the patients, respectively. The IDSA, UK, European, and the Swedish guidelines missed 0%, 20.8%, 41.7%, and 70.8% of the major intracranial findings and 0, 1, 3 and 4 of the 9 patients that prompted a neurosurgical intervention, respectively. All four patients with cerebral herniation met the criteria for all four guidelines.</p><p><strong>Conclusion: </strong>Out of the four international guidelines, only the IDSA recommendations for cranial imaging did not miss any major intracranial abnormality or any finding that prompted a neurosurgical intervention but all guidelines identified herniation.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"857-862"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39936325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Endovascular Treatment of Cavernous Sinus Dural Arteriovenous Fistulas. Institutional Series, Systematic Review and Meta-Analysis. 海绵窦硬膜动静脉瘘的血管内治疗。制度系列、系统回顾与元分析。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2021-12-15 DOI: 10.1007/s00062-021-01107-0
Andrea M Alexandre, Carmelo Lucio Sturiale, Andrea Bartolo, Andrea Romi, Alba Scerrati, Maria Elena Flacco, Francesco D'Argento, Luca Scarcia, Giuseppe Garignano, Iacopo Valente, Emilio Lozupone, Alessandro Pedicelli
{"title":"Endovascular Treatment of Cavernous Sinus Dural Arteriovenous Fistulas. Institutional Series, Systematic Review and Meta-Analysis.","authors":"Andrea M Alexandre,&nbsp;Carmelo Lucio Sturiale,&nbsp;Andrea Bartolo,&nbsp;Andrea Romi,&nbsp;Alba Scerrati,&nbsp;Maria Elena Flacco,&nbsp;Francesco D'Argento,&nbsp;Luca Scarcia,&nbsp;Giuseppe Garignano,&nbsp;Iacopo Valente,&nbsp;Emilio Lozupone,&nbsp;Alessandro Pedicelli","doi":"10.1007/s00062-021-01107-0","DOIUrl":"https://doi.org/10.1007/s00062-021-01107-0","url":null,"abstract":"<p><strong>Purpose: </strong>Endovascular treatment represents the first-line therapy for cavernous sinus dural arteriovenous fistulas (CS-dAVF); however, different approaches and embolic agents as well as occlusion rates, complications and clinical outcomes are reported among the published series. In this study we performed a comprehensive meta-analysis to investigate clinical and radiological outcomes after endovascular treatment of CS-dAVFs.</p><p><strong>Methods: </strong>PubMed, Ovid Medline, Ovid EMBASE, Scopus, and Web of Science were screened for a comprehensive literature review from 1990 to 2020 regarding series of patients treated for CS-dAVF with endovascular approaches. We performed a proportion meta-analysis estimating the pooled rates of each outcome also including data of patients treated in our center.</p><p><strong>Results: </strong>A total of 22 studies reporting 1043 patients and 1066 procedures were included. Chemosis was reported in 559 out of 1043 patients (45.9%), proptosis in 498 (41.5%), and ophthalmoplegia in 344 (23.5%). A transvenous embolization was preferred in 753 cases (63.2%) and coils were used in 712 out of 1066 procedures (57.8%). Overall, 85% (95% confidence interval, CI 69.5-96.1%) of patients had a complete resolution of symptoms, while complications occurred in 7.75% (95% CI 3.82-12.7%) with minimal permanent deficits (0.15%). The mortality rate was 1 out of 1043 patients (< 0.001).</p><p><strong>Conclusion: </strong>A transvenous coiling is the most common endovascular approach for CS-dAVF, achieving a high percentage of radiological and clinical resolution and low complication rates. Transvenous approaches show less complications than transarterial ones, and coils appear safer than liquid embolic agents.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"761-771"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39604453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Hybrid [18F]-F-DOPA PET/MRI Interpretation Criteria and Scores for Glioma Follow-up After Radiotherapy. 脑胶质瘤放疗后随访的杂种[18F]-F-DOPA PET/MRI解释标准及评分。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-02-11 DOI: 10.1007/s00062-022-01139-0
Marc Bertaux, Arnaud Berenbaum, Anna-Luisa Di Stefano, Laura Rozenblum, Marine Soret, Sebastien Bergeret, Khé Hoang-Xuan, Laure-Eugenie Tainturier, Brian Sgard, Marie-Odile Habert, Jean-Yves Delattre, Caroline Dehais, Ahmed Idbaih, Nadya Pyatigorskaya, Aurelie Kas
{"title":"Hybrid [<sup>18</sup>F]-F-DOPA PET/MRI Interpretation Criteria and Scores for Glioma Follow-up After Radiotherapy.","authors":"Marc Bertaux,&nbsp;Arnaud Berenbaum,&nbsp;Anna-Luisa Di Stefano,&nbsp;Laura Rozenblum,&nbsp;Marine Soret,&nbsp;Sebastien Bergeret,&nbsp;Khé Hoang-Xuan,&nbsp;Laure-Eugenie Tainturier,&nbsp;Brian Sgard,&nbsp;Marie-Odile Habert,&nbsp;Jean-Yves Delattre,&nbsp;Caroline Dehais,&nbsp;Ahmed Idbaih,&nbsp;Nadya Pyatigorskaya,&nbsp;Aurelie Kas","doi":"10.1007/s00062-022-01139-0","DOIUrl":"https://doi.org/10.1007/s00062-022-01139-0","url":null,"abstract":"<p><strong>Objective: </strong><sup>18</sup>F‑fluoro-L‑3,4‑dihydroxyphenylalanine positron emission tomography (F‑DOPA PET) is used in glioma follow-up after radiotherapy to discriminate treatment-related changes (TRC) from tumor progression (TP). We compared the performances of a combined PET and MRI analysis with F‑DOPA current standard of interpretation.</p><p><strong>Methods: </strong>We included 76 consecutive patients showing at least one gadolinium-enhanced lesion on the T1‑w MRI sequence (T1G). Two nuclear medicine physicians blindly analyzed PET/MRI images. In addition to the conventional PET analysis, they looked for F‑DOPA uptake(s) outside T1G-enhanced areas (T1G/PET), in the white matter (WM/PET), for T1G-enhanced lesion(s) without sufficiently concordant F‑DOPA uptake (T1G+/PET), and F‑DOPA uptake(s) away from hemorrhagic changes as shown with a susceptibility weighted imaging sequence (SWI/PET). We measured lesions' F‑DOPA uptake ratio using healthy brain background (TBR) and striatum (T/S) as references, and lesions' perfusion with arterial spin labelling cerebral blood flow maps (rCBF). Scores were determined by logistic regression.</p><p><strong>Results: </strong>53 and 23 patients were diagnosed with TP and TRC, respectively. The accuracies were 74% for T/S, 76% for TBR, and 84% for rCBF, with best cut-off values of 1.3, 3.7 and 1.25, respectively. For hybrid variables, best accuracies were obtained with conventional analysis (82%), T1G+/PET (82%) and SWI/PET (81%). T1G+/PET, SWI/PET and rCBF ≥ 1.25 were selected to construct a 3-point score. It outperformed conventional analysis and rCBF with an AUC of 0.94 and an accuracy of 87%.</p><p><strong>Conclusions: </strong>Our scoring approach combining F‑DOPA PET and MRI provided better accuracy than conventional PET analyses for distinguishing TP from TRC in our patients after radiation therapy.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"735-747"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39606273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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