Clinical Neuroradiology最新文献

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Functional Connectivity of Nucleus Accumbens Is Associated with Lifelong Premature Ejaculation in Male Adults : A Resting-state fMRI Study. 成年男性伏隔核的功能连通性与终身早泄有关:一项静息状态fMRI研究。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2021-10-29 DOI: 10.1007/s00062-021-01105-2
Bowen Geng, Ming Gao, Jiayu Wu, Chengxiang Liu, Ruiqing Piao, Guang Yang, Xiao Zeng, Peng Liu
{"title":"Functional Connectivity of Nucleus Accumbens Is Associated with Lifelong Premature Ejaculation in Male Adults : A Resting-state fMRI Study.","authors":"Bowen Geng,&nbsp;Ming Gao,&nbsp;Jiayu Wu,&nbsp;Chengxiang Liu,&nbsp;Ruiqing Piao,&nbsp;Guang Yang,&nbsp;Xiao Zeng,&nbsp;Peng Liu","doi":"10.1007/s00062-021-01105-2","DOIUrl":"https://doi.org/10.1007/s00062-021-01105-2","url":null,"abstract":"<p><strong>Purpose: </strong>Ejaculation represents a crucial component of sexual behavior in men, which is involved in reward functions of certain brain areas including the nucleus accumbens (NAcc). Lifelong premature ejaculation (PE) is one of the most prevalent sexual dysfunctions in men. It is suggested to be related to abnormal brain function. This study aimed to explore changes of the functional connectivity patterns of NAcc and possible correlations of the neuroimaging abnormalities with clinical features in lifelong PE patients.</p><p><strong>Methods: </strong>The sample consisted with 42 lifelong PE patients and 30 healthy controls. All participants underwent functional magnetic resonance imaging scans and clinical symptoms. The functional connectivity (FC) approach was applied to investigate differences of NAcc-seed intrinsic connectivity between two groups and correlation analysis was used to access possible relationships between the imaging findings and clinical features, such as premature ejaculation diagnostic tool (PEDT) or intravaginal ejaculatory latency time (IELT).</p><p><strong>Results: </strong>Results showed that lifelong PE patients had decreased FC between the NAcc and thalamus, superior temporal pole, superior temporal cortex (STC), inferior frontal gyrus (IFG), orbitofrontal cortex, caudate and putamen. A significantly negative correlation between the PEDT score and NAcc-STC connectivity (r = -0.46) was found in lifelong PE patients, while IELT score positively correlated with the NAcc-IFG connectivity (r = 0.48) and NAcc-thalamus connectivity (r = 0.46).</p><p><strong>Conclusion: </strong>The findings may facilitate a more sophisticated understanding of neural mechanisms of lifelong PE, particularly associated with the NAcc-related intrinsic connectivity during the resting state.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"655-663"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39574030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Navigating the Parotid Glands: Anatomy, Imaging Work-up and Next Steps. 导航腮腺:解剖,成像工作和下一步。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-01-21 DOI: 10.1007/s00062-021-01108-z
Ryan McGeary, Patricia A Rhyner, Amit B Desai, Alok A Bhatt
{"title":"Navigating the Parotid Glands: Anatomy, Imaging Work-up and Next Steps.","authors":"Ryan McGeary,&nbsp;Patricia A Rhyner,&nbsp;Amit B Desai,&nbsp;Alok A Bhatt","doi":"10.1007/s00062-021-01108-z","DOIUrl":"https://doi.org/10.1007/s00062-021-01108-z","url":null,"abstract":"<p><p>Evaluation of lesions affecting the parotid gland is often challenging to both clinicians and radiologists. This article reviews parotid anatomy and function, as it relates to various lesions that may occur within the gland. Key morphlogic features of lesions are discussed with an emphasis on those that warrant biopsy and those that do not need biopsy. Various biopsy methods using ultrasound and computed tomography are reviewed.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"615-623"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39845081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Flow Diverter Treatment of Ruptured Basilar Artery Perforator Aneurysms : A Multicenter Experience. 基底动脉穿支动脉瘤破裂的分流治疗:多中心经验。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-01-20 DOI: 10.1007/s00062-021-01133-y
Samer Elsheikh, Markus Möhlenbruch, Fatih Seker, Ansgar Berlis, Christoph Maurer, Naci Kocer, Ala Jamous, Daniel Behme, Christian Taschner, Horst Urbach, Stephan Meckel
{"title":"Flow Diverter Treatment of Ruptured Basilar Artery Perforator Aneurysms : A Multicenter Experience.","authors":"Samer Elsheikh,&nbsp;Markus Möhlenbruch,&nbsp;Fatih Seker,&nbsp;Ansgar Berlis,&nbsp;Christoph Maurer,&nbsp;Naci Kocer,&nbsp;Ala Jamous,&nbsp;Daniel Behme,&nbsp;Christian Taschner,&nbsp;Horst Urbach,&nbsp;Stephan Meckel","doi":"10.1007/s00062-021-01133-y","DOIUrl":"https://doi.org/10.1007/s00062-021-01133-y","url":null,"abstract":"<p><strong>Purpose: </strong>Ruptured basilar artery perforator aneurysms (BAPAs) represent a very rare cause of subarachnoid hemorrhage and an under-reported subtype of cerebral aneurysm. There is no consensus for the optimal treatment strategy (conservative vs. surgical vs. various endovascular approaches). We aim to present a multicenter experience of BAPA treatment using flow-diverter (FD) stents.</p><p><strong>Methods: </strong>At five tertiary neurovascular centers, all cases of ruptured BAPAs treated by FD were retrospectively collected. Baseline imaging and clinical characteristics, complications, as well as early and long-term angiographic and clinical outcome (mRS) were analyzed.</p><p><strong>Results: </strong>Eighteen patients (mean age, 57 years; SD, ±10.7 years) with acute SAH related to a BAPA were treated using 18 FD stents. Aneurysms were detected on initial imaging study in 28%; delayed diagnosis was triggered by clinical deterioration due to rebleeding in 15%. No rebleeding after FD was seen, 28% developed FD-related ischemic complications. At long term (n = 16), overall mortality was 13% (2/16), and favorable outcome (mRS 0-2) was 81% (13/16). All BAPAs (n = 13) were completely occluded at long-term angiographic follow-up.</p><p><strong>Conclusion: </strong>In our multicenter experience, FD treatment of ruptured BAPAs appears to have comparable safety and efficacy outcomes to FD treatment of other ruptured posterior circulation aneurysms as well as to the conservative management of BAPAs. This treatment strategy for a ruptured BAPA achieved a high rate of angiographic occlusion and favorable clinical outcome; however, as the conservative management also seems to offer similar clinical outcomes an individualized treatment decision is warranted. Future prospective studies comparing both approaches are required.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"783-789"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39845082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
A Novel Subtraction Method to Reduce Metal Artifacts of Cerebral Aneurysm Embolism Coils. 一种减少脑动脉瘤栓塞线圈金属伪影的新减法。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-01-22 DOI: 10.1007/s00062-021-01125-y
Hanpei Zheng, Ming Yang, Yuxi Jia, Lan Zhang, Xiaojie Sun, Yangjing Zhang, Zhuang Nie, Hongying Wu, Xiaohui Zhang, Ziqiao Lei, Wang Jing
{"title":"A Novel Subtraction Method to Reduce Metal Artifacts of Cerebral Aneurysm Embolism Coils.","authors":"Hanpei Zheng,&nbsp;Ming Yang,&nbsp;Yuxi Jia,&nbsp;Lan Zhang,&nbsp;Xiaojie Sun,&nbsp;Yangjing Zhang,&nbsp;Zhuang Nie,&nbsp;Hongying Wu,&nbsp;Xiaohui Zhang,&nbsp;Ziqiao Lei,&nbsp;Wang Jing","doi":"10.1007/s00062-021-01125-y","DOIUrl":"https://doi.org/10.1007/s00062-021-01125-y","url":null,"abstract":"<p><strong>Objective: </strong>To investigate a novel subtraction method (S-MAR), combing metal artifact reduction (MAR), virtual monochromatic imaging (VMI), and subtraction CT angiography (CTA) to remove the metal artifacts of coils after endovascular embolotherapy of intracranial aneurysms.</p><p><strong>Method: </strong>In this retrospective study, 29 patients with 38 coils after endovascular embolotherapy of intracranial aneurysms who underwent cerebral CTA using a dual-layer detector spectral CT were included. Conventional CT images (CI), virtual non-enhanced (VNC) images and VMI ranging from 40 to 120 KeV in steps of 10 were reconstructed. These images were then postprocessed to CI<sub>MAR</sub>, VMI<sub>MAR</sub> and VNC<sub>MAR</sub> with MAR software (O-MAR; Philips Healthcare, Cleveland, OH, USA). The novel subtraction method (S-MAR) was derived from subtraction imaging between VNC<sub>MAR</sub> and the optimal VMI<sub>MAR</sub>. Contrast-to-noise (CNR) and Noise<sub>(Background)</sub> of CI, CI<sub>MAR</sub>, VMI, and VMI<sub>MAR</sub> were calculated quantitatively. Two Independent radiologists qualitatively assessed artifacts in all images using coil artifact score (CA score), a 5-point Likert scale. Besides, all coils were divided into two groups (group 1: diameter < 5.0 mm, group 2: diameter ≥ 5.0 mm). Differences between two groups were statistically analyzed.</p><p><strong>Results: </strong>The optimal KeV was 40 KeV. Strong correlations between diameter of coils and the CA score of CI were found (r<sub>s</sub> = 0.652, P < 0.05). CNR, Noise and CA score were significantly improved by CI<sub>MAR</sub> and VMI<sub>MAR</sub> compared with CI (P < 0.05). The S‑MAR showed significantly better performance compared with CI, CI<sub>MAR</sub>, VMI, and VMI<sub>MAR</sub> in reducing metal coil artifacts according to the CA score (P < 0.05), especially in group 2.</p><p><strong>Conclusion: </strong>The novel S‑MAR proved to be a promising method to reduce coil metal artifacts and elevate the vessel visualization adjacent to coils. It could develop to be widely used in cerebral CTA after coiled aneurysms.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"687-694"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39847909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Association of Stent-Retriever Characteristics in Establishing Successful Reperfusion During Mechanical Thrombectomy : Results from the ESCAPE-NA1 Trial. ESCAPE-NA1试验结果:机械取栓过程中支架回收器特性与成功再灌注的关系
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-01-07 DOI: 10.1007/s00062-021-01123-0
Petra Cimflova, Nishita Singh, Johanna M Ospel, Martha Marko, Nima Kashani, Arnuv Mayank, Ricardo Hanel, Diogo C Haussen, Aditya Bharatha, David Volders, Manraj K S Heran, Alexandre Y Poppe, Brian van Adel, Bijoy K Menon, Manish Joshi, Andrew Demchuk, Ryan McTaggart, Raul G Nogueira, Jeremy L Rempel, Charlotte Zerna, Michael Tymianski, Michael D Hill, Mayank Goyal, Mohammed A Almekhlafi
{"title":"Association of Stent-Retriever Characteristics in Establishing Successful Reperfusion During Mechanical Thrombectomy : Results from the ESCAPE-NA1 Trial.","authors":"Petra Cimflova,&nbsp;Nishita Singh,&nbsp;Johanna M Ospel,&nbsp;Martha Marko,&nbsp;Nima Kashani,&nbsp;Arnuv Mayank,&nbsp;Ricardo Hanel,&nbsp;Diogo C Haussen,&nbsp;Aditya Bharatha,&nbsp;David Volders,&nbsp;Manraj K S Heran,&nbsp;Alexandre Y Poppe,&nbsp;Brian van Adel,&nbsp;Bijoy K Menon,&nbsp;Manish Joshi,&nbsp;Andrew Demchuk,&nbsp;Ryan McTaggart,&nbsp;Raul G Nogueira,&nbsp;Jeremy L Rempel,&nbsp;Charlotte Zerna,&nbsp;Michael Tymianski,&nbsp;Michael D Hill,&nbsp;Mayank Goyal,&nbsp;Mohammed A Almekhlafi","doi":"10.1007/s00062-021-01123-0","DOIUrl":"https://doi.org/10.1007/s00062-021-01123-0","url":null,"abstract":"<p><strong>Background: </strong>Successful reperfusion determines the treatment effect of endovascular thrombectomy. We evaluated stent-retriever characteristics and their relation to reperfusion in the ESCAPE-NA1 trial.</p><p><strong>Methods: </strong>Independent re-scoring of reperfusion grade for each attempt was conducted. The following characteristics were evaluated: stent-retriever length and diameter, thrombus position within stent-retriever, bypass effect, deployment in the superior or inferior MCA trunk, use of balloon guide catheter and distal access catheter. Primary outcome was successful reperfusion defined as expanded thrombolysis in cerebral infarction (eTICI) 2b-3 per attempt. The secondary outcome was successful reperfusion eTICI 2b-3 after the first attempt. Separate regression models for each stent-retriever characteristic and an exploratory multivariable modeling to test the impact of all characteristics on successful reperfusion were built.</p><p><strong>Results: </strong>Of 1105 patients in the trial, 809 with the stent-retriever use (1241 attempts) were included in the primary analysis. The stent-retriever was used as the first-line approach in 751 attempts. A successful attempt was associated with thrombus position within the proximal or middle third of the stent (OR 2.06; 95% CI: 1.24-3.40 and OR 1.92; 95% CI: 1.16-3.15 compared to the distal third respectively) and with bypass effect (OR 1.7; 95% CI: 1.07-2.72). Thrombus position within the proximal or middle third (OR 2.80; 95% CI: 1.47-5.35 and OR 2.05; 95% CI: 1.09-3.84, respectively) was associated with first-pass eTICI 2b-3 reperfusion. In the exploratory analysis accounting for all characteristics, bypass effect was the only independent predictor of eTICI 2b-3 reperfusion (OR 1.95; 95% CI: 1.10-3.46).</p><p><strong>Conclusion: </strong>The presence of bypass effect and thrombus positioning within the proximal and middle third of the stent-retriever were strongly associated with successful reperfusion.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"799-807"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39905417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Efficient Claustrum Segmentation in T2-weighted Neonatal Brain MRI Using Transfer Learning from Adult Scans. 利用成人扫描的迁移学习对t2加权新生儿脑MRI进行有效的屏状体分割。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-01-24 DOI: 10.1007/s00062-021-01137-8
Antonia Neubauer, Hongwei Bran Li, Jil Wendt, Benita Schmitz-Koep, Aurore Menegaux, David Schinz, Bjoern Menze, Claus Zimmer, Christian Sorg, Dennis M Hedderich
{"title":"Efficient Claustrum Segmentation in T2-weighted Neonatal Brain MRI Using Transfer Learning from Adult Scans.","authors":"Antonia Neubauer,&nbsp;Hongwei Bran Li,&nbsp;Jil Wendt,&nbsp;Benita Schmitz-Koep,&nbsp;Aurore Menegaux,&nbsp;David Schinz,&nbsp;Bjoern Menze,&nbsp;Claus Zimmer,&nbsp;Christian Sorg,&nbsp;Dennis M Hedderich","doi":"10.1007/s00062-021-01137-8","DOIUrl":"https://doi.org/10.1007/s00062-021-01137-8","url":null,"abstract":"<p><strong>Purpose: </strong>Intrauterine claustrum and subplate neuron development have been suggested to overlap. As premature birth typically impairs subplate neuron development, neonatal claustrum might indicate a specific prematurity impact; however, claustrum identification usually relies on expert knowledge due to its intricate structure. We established automated claustrum segmentation in newborns.</p><p><strong>Methods: </strong>We applied a deep learning-based algorithm for segmenting the claustrum in 558 T2-weighted neonatal brain MRI of the developing Human Connectome Project (dHCP) with transfer learning from claustrum segmentation in T1-weighted scans of adults. The model was trained and evaluated on 30 manual bilateral claustrum annotations in neonates.</p><p><strong>Results: </strong>With only 20 annotated scans, the model yielded median volumetric similarity, robust Hausdorff distance and Dice score of 95.9%, 1.12 mm and 80.0%, respectively, representing an excellent agreement between the automatic and manual segmentations. In comparison with interrater reliability, the model achieved significantly superior volumetric similarity (p = 0.047) and Dice score (p < 0.005) indicating stable high-quality performance. Furthermore, the effectiveness of the transfer learning technique was demonstrated in comparison with nontransfer learning. The model can achieve satisfactory segmentation with only 12 annotated scans. Finally, the model's applicability was verified on 528 scans and revealed reliable segmentations in 97.4%.</p><p><strong>Conclusion: </strong>The developed fast and accurate automated segmentation has great potential in large-scale study cohorts and to facilitate MRI-based connectome research of the neonatal claustrum. The easy to use models and codes are made publicly available.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"665-676"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39855217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Signal Intensity Evaluation in the Dentate Nucleus and Subcortical Gray Matter : Effect of Several Administrations of Gadoterate Meglumine in Multiple Sclerosis. 齿状核和皮层下灰质的信号强度评估:多发性硬化症患者多次服用Gadoterate Meglumine的效果。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2021-02-25 DOI: 10.1007/s00062-021-00995-6
Salem Hannoun, Gabriel Kocevar, Pekes Codjia, Delphine Maucort-Boulch, François Cotton, Sandra Vukusic, Françoise Durand-Dubief, Dominique Sappey-Marinier
{"title":"Signal Intensity Evaluation in the Dentate Nucleus and Subcortical Gray Matter : Effect of Several Administrations of Gadoterate Meglumine in Multiple Sclerosis.","authors":"Salem Hannoun,&nbsp;Gabriel Kocevar,&nbsp;Pekes Codjia,&nbsp;Delphine Maucort-Boulch,&nbsp;François Cotton,&nbsp;Sandra Vukusic,&nbsp;Françoise Durand-Dubief,&nbsp;Dominique Sappey-Marinier","doi":"10.1007/s00062-021-00995-6","DOIUrl":"https://doi.org/10.1007/s00062-021-00995-6","url":null,"abstract":"<p><strong>Purpose: </strong>Several studies reported gadolinium deposition in the dentate nuclei (DN) and the globus pallidus (GP) that was associated to linear GBCA administrations rather than macrocyclic. It is therefore imperative to evaluate and assess the safety of cumulative administration of gadoterate meglumine (macrocyclic). Thus, T1-weighted images (T1WI) of multiple sclerosis (MS) patients longitudinally followed for 4 years were retrospectively analyzed.</p><p><strong>Methods: </strong>In this study 44 patients, 10 with clinically isolated syndrome (CIS), 24 relapsing-remitting MS (RRMS) and 10 primary-progressive MS (PPMS) were examined every 6 months (first four scans) and then with a 1-year interval (last two scans). Image processing consisted in reorienting unenhanced T1WI to standard space, followed by B1 inhomogeneity correction. A patient-specific template was then generated to normalize T1WI signal intensity (SI) and segment the DN and subcortical GM structures. All structures were then transformed to each patient space in order to measure the SI in each region. The cerebellar peduncles (CP) and semi-oval (SO) white matter were then manually delineated and used as reference to calculate SI ratios in the DN and subcortical GM structures. A linear mixed-effect model was finally applied to longitudinally analyze SI variations.</p><p><strong>Results: </strong>The SI measurements performed in all structures showed no significant increases with the cumulative GBCA administration.</p><p><strong>Conclusion: </strong>This study showed no significant SI increases within the DN and subcortical GM structures of longitudinally followed MS patients even with the cumulative administration of the macrocyclic GBCA gadoterate meglumine.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"677-685"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00062-021-00995-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25403075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Direct Endovascular Thrombectomy Alone vs. Bridging Thrombolysis for Patients with Acute Ischemic Stroke : A Meta-analysis. 急性缺血性卒中患者直接血管内取栓vs桥式溶栓:荟萃分析
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2021-11-12 DOI: 10.1007/s00062-021-01116-z
Kyoung Min Jang, Hyun Ho Choi, Myoung-Jin Jang, Young Dae Cho
{"title":"Direct Endovascular Thrombectomy Alone vs. Bridging Thrombolysis for Patients with Acute Ischemic Stroke : A Meta-analysis.","authors":"Kyoung Min Jang,&nbsp;Hyun Ho Choi,&nbsp;Myoung-Jin Jang,&nbsp;Young Dae Cho","doi":"10.1007/s00062-021-01116-z","DOIUrl":"https://doi.org/10.1007/s00062-021-01116-z","url":null,"abstract":"<p><strong>Purpose: </strong>Although the current guidelines recommend bridging thrombolysis (BT) therapy, which is intravenous thrombolysis (IVT) followed by endovascular thrombectomy (EVT), for patients with acute ischemic stroke from large vessel occlusion (AIS-LVO), the effectiveness and safety of IVT remain controversial. We performed a meta-analysis to demonstrate the non-inferiority of direct EVT alone (DEVT) compared to BT for the efficacy and safety in patients with AIS-LVO who were eligible for IVT.</p><p><strong>Methods: </strong>The literature was searched in big databases between 1 January 1990 and 1 April 2021. The search included both randomized clinical trials (RCTs) and nonrandomized studies (NRSs) that compared DEVT with BT for patients with AIS-LVO who were eligible for IVT (time from stroke onset ≤ 4.5 h). Only NRSs with good intergroup variable matching were included in the study. Outcomes measured included 90-day functional independence, mortality, symptomatic intracranial hemorrhage (sICH), and successful recanalization. The noninferiority margin for risk difference was set at 5% from the literature review.</p><p><strong>Results: </strong>Three RCTs (n = 1094) and four NRSs (n = 1366) were included in the meta-analysis. There were 1227 patients (49.9%) in the DEVT group and 1233 patients (50.1%) in the BT group. A statistically significant noninferiority of DEVT compared to BT was concluded in 90-day functional independence, mortality and successful reperfusion. Even in the sICH rate, DEVT group showed a superiority (risk difference, -2%; 95% confidence interval, -4 to -0.002%).</p><p><strong>Conclusion: </strong>Evidence from RCTs and observational NRSs supports the use of DEVT (without IVT) as the first choice for treatment of patients with AIS-LVO within a time span of 4.5 h or less from stroke onset.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"603-613"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39615242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Compressed SENSE in Pediatric Brain Tumor MR Imaging : Assessment of Image Quality, Examination Time and Energy Release. 压缩感在儿童脑肿瘤磁共振成像中的应用:图像质量、检查时间和能量释放的评估。
IF 2.8 3区 医学
Clinical Neuroradiology Pub Date : 2022-09-01 Epub Date: 2022-01-07 DOI: 10.1007/s00062-021-01112-3
Rieke L Meister, Michael Groth, Julian H W Jürgens, Shuo Zhang, Jan H Buhk, Jochen Herrmann
{"title":"Compressed SENSE in Pediatric Brain Tumor MR Imaging : Assessment of Image Quality, Examination Time and Energy Release.","authors":"Rieke L Meister,&nbsp;Michael Groth,&nbsp;Julian H W Jürgens,&nbsp;Shuo Zhang,&nbsp;Jan H Buhk,&nbsp;Jochen Herrmann","doi":"10.1007/s00062-021-01112-3","DOIUrl":"https://doi.org/10.1007/s00062-021-01112-3","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the image quality, examination time, and total energy release of a standardized pediatric brain tumor magnetic resonance imaging (MRI) protocol performed with and without compressed sensitivity encoding (C-SENSE). Recently introduced as an acceleration technique in MRI, we hypothesized that C‑SENSE would improve image quality, reduce the examination time and radiofrequency-induced energy release compared with conventional examination in a pediatric brain tumor protocol.</p><p><strong>Methods: </strong>This retrospective study included 22 patients aged 2.33-18.83 years with different brain tumor types who had previously undergone conventional MRI examination and underwent follow-up C‑SENSE examination. Both examinations were conducted with a 3.0-Tesla device and included pre-contrast and post-contrast T1-weighted turbo-field-echo, T2-weighted turbo-spin-echo, and fluid-attenuated inversion recovery sequences. Image quality was assessed in four anatomical regions of interest (tumor area, cerebral cortex, basal ganglia, and posterior fossa) using a 5-point scale. Reader preference between the standard and C‑SENSE images was evaluated. The total examination duration and energy deposit were compared based on scanner log file analysis.</p><p><strong>Results: </strong>Relative to standard examinations, C‑SENSE examinations were characterized by shorter total examination times (26.1 ± 3.93 vs. 22.18 ± 2.31 min; P = 0.001), reduced total energy deposit (206.0 ± 19.7 vs. 92.3 ± 18.2 J/kg; P < 0.001), and higher image quality (overall P < 0.001).</p><p><strong>Conclusion: </strong>C‑SENSE contributes to the improvement of image quality, reduction of scan times and radiofrequency-induced energy release relative to the standard protocol in pediatric brain tumor MRI.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 3","pages":"725-733"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39793432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
The case against endovascular thrombectomy in neonates with arterial ischemic stroke. 血管内血栓切除术治疗新生儿动脉缺血性脑卒中
IF 2.4 3区 医学
Clinical Neuroradiology Pub Date : 2022-06-01 DOI: 10.1007/s00062-022-01153-2
Adam Kirton, Lori C Jordan, Darren B Orbach, Heather J Fullerton
{"title":"The case against endovascular thrombectomy in neonates with arterial ischemic stroke.","authors":"Adam Kirton, Lori C Jordan, Darren B Orbach, Heather J Fullerton","doi":"10.1007/s00062-022-01153-2","DOIUrl":"10.1007/s00062-022-01153-2","url":null,"abstract":"","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":"32 1","pages":"581-582"},"PeriodicalIF":2.4,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47565597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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