Clinical Neuroradiology最新文献

{"title":"Caution for Forearm Radial Artery Tortuosity: a Risk of Transradial Neuroendovascular Procedure Failure.","authors":"Fukutaro Ohgaki, Nagatsuki Tomura, Takashi Shuto, Shigeo Matsunaga, Jo Sasame, Kei Iwamoto, Shuto Fushimi, Hisao Aimi","doi":"10.1007/s00062-025-01541-4","DOIUrl":"https://doi.org/10.1007/s00062-025-01541-4","url":null,"abstract":"<p><strong>Purpose: </strong>The transradial artery approach (TRA) has recently gained popularity in neuroendovascular procedures with its advantages of the fewer complications and reduced invasiveness. However, forearm radial artery (RA) tortuosity has led to procedural failure in some cases. Therefore, this study aimed to investigate the influence of forearm RA tortuosity on TRA failure and evaluate its association with patients' characteristics and the procedure-related factors.</p><p><strong>Methods: </strong>We retrospectively examined the characteristics of 239 patients who underwent neuroendovascular procedures at our facility between January 2023 and November 2024.</p><p><strong>Results: </strong>Among the 239 patients, 28 exhibited forearm RA tortuosity, and switching from TRA was significantly more frequent among these patients (64.3% vs. 5.2%, p < 0.01). Additionally, they were significantly older (74.8 vs. 60.6 [years], p < 0.01), shorter in stature (1.55 vs. 1.62 [m], p < 0.01), and lighter in body weight (53.0 vs. 60.0 [kg], p < 0.01). Moreover, they were complicated with dyslipidemia (57.1% vs. 36.5%, p = 0.04). The cut-off values associated with an increased risk of forearm RA tortuosity were age > 71 years (p < 0.0001), height < 1.60 m for men (p = 0.0365), and height < 1.55 m for women (p = 0.0010).</p><p><strong>Conclusion: </strong>Forearm RA tortuosity significantly influenced the choice of neuroendovasucular approach and was significantly correlated with the age and physique of patients. Pre-procedural evaluation of the forearm RA course is crucial in TRA, and preparation for switching the approach from TRA was hoped in high-risk cases.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subject-specific Functional ROIs Enhance Reliability in Language FMRI.","authors":"Julia My Van Kube, Luisa Katrin Thomas, Peter Dechent, Christian Heiner Riedel, Nicole E Neef","doi":"10.1007/s00062-025-01534-3","DOIUrl":"https://doi.org/10.1007/s00062-025-01534-3","url":null,"abstract":"<p><strong>Purpose: </strong>Functional MRI can be used to identify individual language-sensitive brain regions in the setting of presurgical diagnostics to improve functional postoperative outcome. In this study, a proven language task was adapted into German and tested with regard to its effectiveness, robustness and reliability in a time frame appropriate for the clinical setting. In addition, two different analysis approaches were compared to address the problem of arbitrary statistical thresholds commonly used in the clinical routine to derive contrast maps.</p><p><strong>Methods: </strong>On two different days, 24 healthy volunteers were examined in a 3T MRI, whereby the task was run twice in each session. The fMRI included two conditions in a block design, reading of sentences and reading of pronounceable nonword lists. We quantified brain activity by using subject-specific, functionally defined ROIs on the one hand and standardized, anatomically defined ROIs on the other. We then tested, whether the two different analyses indicated robust activation of language-sensitive brain regions, and whether effect sizes were reliable across sessions.</p><p><strong>Results: </strong>Subject-specific functional ROIs as well as anatomical ROIs led to significant positive effect sizes in the major language sensitive regions of the left hemisphere. However, subject-specific functional ROIs resulted in significantly larger effect sizes and a higher reliability in comparison to anatomical ROIs.</p><p><strong>Conclusion: </strong>The choice of analysis method has a significant impact on the result. For paradigms with short measurement times and little signal change as common in clinical routine, it is highly recommended to use the subject-specific functional ROIs approach.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes and Predictors of Precise Stent Placement in Patients with Isolated Pulsatile Tinnitus.","authors":"Hui Su, Baomin Li, Jun Wang, Zhihua Du, Xinfeng Liu, Rongju Zhang, Bin Lv, Xiangyu Cao","doi":"10.1007/s00062-025-01536-1","DOIUrl":"https://doi.org/10.1007/s00062-025-01536-1","url":null,"abstract":"<p><strong>Purpose: </strong>There is no dedicated stent for isolated venous pulsatile tinnitus (IVPT). This retrospective study aimed to evaluate the the clinical outcomes and associated factors of Precise stent (Cordis) implantation in the management of IVPT.</p><p><strong>Methods: </strong>We analyzed data from IVPT patients treated at our center between December 2009 and August 2024. Baseline characteristics, venous sinus morphology, endovascular techniques, clinical outcomes, and follow-up data were reviewed.</p><p><strong>Results: </strong>Among 111 IVPT patients, 64 (57.7%) underwent cranial venous sinus stenting (CVSS) using the Precise stent, with 59 (92.2%) being women. IVPT resolved immediately after CVSS in all cases. Over a mean follow-up of 90.9 ± 42.7 months, 18 patients (28.1%) experienced postoperative headaches, all female, with 61.1% reporting symptoms within the first week. Headaches had a mean duration of 44.9 ± 70.5 days and an average visual analog scale score of 3.4 ± 1.5, with 94.5% described as pressure-like. Younger age was significantly associated with headache occurrence (P < 0.05), while other factors, including stent size and operation time, showed no correlation.</p><p><strong>Conclusion: </strong>Precise stent implantation in venous sinus is highly effective for treating IVPT, but postoperative headaches, particularly in younger women, are a common complication. Further research is needed to mitigate these side effects and enhance long-term patient outcomes.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Learning Model for Automated Segmentation of Orbital Structures in MRI Images.","authors":"Esmira Bakhshaliyeva, Lara Noelle Reiner, Moudather Chelbi, Jawed Nawabi, Anna Tietze, Michael Scheel, Mike Wattjes, Andrea Dell'Orco, Aymen Meddeb","doi":"10.1007/s00062-025-01535-2","DOIUrl":"https://doi.org/10.1007/s00062-025-01535-2","url":null,"abstract":"<p><strong>Background: </strong>Magnetic resonance imaging (MRI) is a crucial tool for visualizing orbital structures and detecting eye pathologies. However, manual segmentation of orbital anatomy is challenging due to the complexity and variability of the structures. Recent advancements in deep learning (DL), particularly convolutional neural networks (CNNs), offer promising solutions for automated segmentation in medical imaging. This study aimed to train and evaluate a U-Net-based model for the automated segmentation of key orbital structures.</p><p><strong>Methods: </strong>This retrospective study included 117 patients with various orbital pathologies who underwent orbital MRI. Manual segmentation was performed on four anatomical structures: the ocular bulb, ocular tumors, retinal detachment, and the optic nerve. Following the UNet autoconfiguration by nnUNet, we conducted a five-fold cross-validation and evaluated the model's performances using Dice Similarity Coefficient (DSC) and Relative Absolute Volume Difference (RAVD) as metrics.</p><p><strong>Results: </strong>nnU-Net achieved high segmentation performance for the ocular bulb (mean DSC: 0.931) and the optic nerve (mean DSC: 0.820). Segmentation of ocular tumors (mean DSC: 0.788) and retinal detachment (mean DSC: 0.550) showed greater variability, with performance declining in more challenging cases. Despite these challenges, the model achieved high detection rates, with ROC AUCs of 0.90 for ocular tumors and 0.78 for retinal detachment.</p><p><strong>Conclusions: </strong>This study demonstrates nnU-Net's capability for accurate segmentation of orbital structures, particularly the ocular bulb and optic nerve. However, challenges remain in the segmentation of tumors and retinal detachment due to variability and artifacts. Future improvements in deep learning models and broader, more diverse datasets may enhance segmentation performance, ultimately aiding in the diagnosis and treatment of orbital pathologies.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isochrone-based Identification of Gaps in Neurovascular Care in Germany.","authors":"Marius Vach, Christian Rubbert, Julian Caspers, Sven G Meuth, Marc Pawlitzki, Lars Masanneck","doi":"10.1007/s00062-025-01537-0","DOIUrl":"https://doi.org/10.1007/s00062-025-01537-0","url":null,"abstract":"<p><strong>Purpose: </strong>Modern endovascular techniques enable the treatment of various neurovascular diseases. Given the complexity of these interventions, a certification system was introduced to ensure standardized care at specialized treatment centers. We used a driving-time-based isochrone approach to identify care gaps in different German Society of Interventional Radiology (DeGIR) certified neurovascular treatment centers.</p><p><strong>Methods: </strong>DeGIR-certified neurovascular centers for minimally invasive stroke care (module E), neurovascular vessel anomalies (module F), and neurovascular therapy (module EF) were geocoded and driving-time-based isochrones were calculated for 30, 60, 90, and 120 min. The resulting contours were aggregated and combined with the 2025 population estimates from the Global Human Settlement Layer to estimate residents' access.</p><p><strong>Results: </strong>The analysis identified gaps in under-60-minute reachability, notably in northeastern Germany and parts of Rhineland-Palatinate, Saarland, and the southwest, with modules EF and F most affected, while module E fared better. Within 120 min, coverage was nearly complete across all modules. On a population level, 59.4% of residents lived within 30 min, 92.81% within 60 min, and 99.98% within 120 min of a module E center. Module F reached 45.8%, 84.26%, and 99.73%, respectively, with module EF showing intermediate accessibility.</p><p><strong>Discussion: </strong>The driving-time-based isochrone approach identifies regions where access to specialized neurovascular care is limited-a critical issue in emergencies like stroke or aneurysm hemorrhage. Although immediate stroke care is generally more accessible than care for neurovascular anomalies, thrombectomy within an acceptable timeframe is not available to the entire population. These findings can guide strategies to enhance neurovascular care across Germany.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microstructural Characteristics of Cervical Spinal Cord Using High Angular Resolution Diffusion Imaging (HARDI) and Tractography in Healthy Subjects.","authors":"Corentin Dauleac, Amine Boukhari, Timothée Jacquesson, Carole Frindel, François Cotton","doi":"10.1007/s00062-024-01481-5","DOIUrl":"10.1007/s00062-024-01481-5","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to characterize spinal cord microstructure in healthy subjects using high angular resolution diffusion imaging (HARDI) and tractography.</p><p><strong>Methods: </strong>Forty-nine healthy subjects (18-50 years, divided into 2 age groups) were included in a prospective study. HARDI of the cervical spinal cord were acquired using a 3T MRI scanner with: 64 directions, b‑value: 1000s/mm², reduced field-of-view (zonally magnified oblique multi-slice), and opposed phase-encoding directions. Distortions were corrected using the FSL software package. Fiber tracking was performed using a deterministic approach with DSI-Studio software. Tensor metrics-fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), radial diffusivity (RD)-and tractography statistics were then extracted, at each spine level, and after grey-white matter segmentation.</p><p><strong>Results: </strong>The microstructural organization of the spinal cord differed between upper and lower cervical spine levels: FA, and AD significantly decreased (p < 0.001); and RD significantly increased (p < 0.05) in lower levels, demonstrating changes in axonal density and myelinated fibers according to a cranio-caudal axis. FA, MD, AD, and RD values were significantly higher in spinal cord white matter (p < 0.0001), compared to grey matter. Age was not associated with a significant change in FA, while there is for MD, AD and RD (p < 0.05). Spinal cord tractography may provide information on the architectural organization of fibers and spinal tracts.</p><p><strong>Conclusion: </strong>This study proposes a database in cervical spinal cord HARDI, allowing to study the microstructural organization of the spinal cord in healthy subjects, and providing a foundation for comparison with patients presenting spinal cord pathologies.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"315-324"},"PeriodicalIF":2.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Intracranial Aneurysms with the FRED X Flow Diverter Stent: Mid-term Angiographic and Safety Results.","authors":"David W Wen, James Ayre, Mani Puthuran, Paul Maliakal, Souhyb Masri, Richard Pullicino, Aubrey Smith, Feyi Babatola, Gilbert Gravino, Nasr Abdelsalam, Hamed Nejadhamzeeigilani, Arun Chandran","doi":"10.1007/s00062-024-01487-z","DOIUrl":"10.1007/s00062-024-01487-z","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of our study was to assess the mid-term efficacy and safety of the FRED X flow diverting stent (FDS) in the treatment of intracranial aneurysms. The FRED X FDS is relatively new with limited data on its longer-term effectiveness and safety profile.</p><p><strong>Methods: </strong>Patients with intracranial aneurysms treated with the FRED X FDS at two UK centres, between March 2021 and July 2022 with at least 18 months follow-up, were retrospectively reviewed. Clinical, procedural and imaging data was analyzed.</p><p><strong>Results: </strong>Twenty-two patients with 24 aneurysms treated with the FRED X device, and had completed at least 18 months of follow-up, were included in this study. The rate of complete aneurysm occlusion (Raymond-Roy Class I) was 83.3% at a mean follow-up duration of 21.5 months. One case of major adverse event (4.3%) related to a post-procedural stroke which is also the only case of permanent neurological deficit (4.3%) in our cohort. Three cases of minor adverse events (13.0%) and 2 cases of asymptomatic adverse events (8.7%) were also recorded.</p><p><strong>Conclusion: </strong>Use of the FRED X FDS to treat intracranial aneurysms has acceptable safety profile and efficacy in the mid-term.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"379-384"},"PeriodicalIF":2.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epstein-Barr Virus Encephalitis Mimicking Herpes Encephalitis On Neuroimaging: A Case Report.","authors":"Negin Eissazade, Mahsa Peykani, Mostafa Almasi-Dooghaee","doi":"10.1007/s00062-024-01485-1","DOIUrl":"10.1007/s00062-024-01485-1","url":null,"abstract":"","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"413-415"},"PeriodicalIF":2.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperdense Middle Cerebral Artery Sign as a Predictor of First-Pass Recanalization and Favorable Outcomes in Direct Thrombectomy Patients.","authors":"Yiyang Sun, Dapeng Sun, Baixue Jia, Xiaochuan Huo, Xu Tong, Anxin Wang, Ning Ma, Feng Gao, Dapeng Mo, Zhongrong Miao","doi":"10.1007/s00062-024-01484-2","DOIUrl":"10.1007/s00062-024-01484-2","url":null,"abstract":"<p><strong>Background: </strong>The Hyperdense Middle Cerebral Artery Sign (HMCAS) is an early marker of acute MCA occlusion on non-contrast CT (NCCT), which has been linked with stroke type and thrombus composition.</p><p><strong>Aims: </strong>To assess the prognostic value of HMCAS in M1 occlusion patients treated with endovascular thrombectomy and explore its predictive value across different patients.</p><p><strong>Methods: </strong>Patients with M1 occlusion were selected from the ANGEL-ACT registry, which comprised 1793 individuals. Cohorts were divided based on the presence of HMCAS. The primary outcome was functional independence (mRS 0-2) at 90 days. Secondary outcomes included excellent outcome (mRS 0-1), good functional outcome (mRS 0-3), modified first pass effect (mFPE), successful recanalization, intracranial hemorrhage, and 90-day mortality. Propensity score matching (PSM) was employed to adjust for confounders, with 96 patients in each matched group. Subgroup analysis was performed to determine whether the effect of HMCAS on clinical outcomes differed between groups.</p><p><strong>Results: </strong>Among 714 acute M1 occlusion patients, 96 (13.4%) had HMCAS. PSM analysis showed that HMCAS was independently associated with mFPE (OR: 1.97, 95% CI: 1.04-3.75, p = 0.038) but had no significant effects on other clinical outcomes. There was a significant association between HMCAS and functional independence for patients who underwent direct thrombectomy but not for patients who underwent bridging therapy (P for interaction = 0.033).</p><p><strong>Conclusion: </strong>This study indicates that in patients with acute M1 occlusion undergoing EVT, HMCAS on pretreatment NCCT is not significantly associated with functional independence but is linked to a higher first-pass recanalization rate. Its clinical impact on outcomes depends on whether intravenous thrombolysis is administered before thrombectomy.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"325-336"},"PeriodicalIF":2.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Influencing Favourable Clinical Outcomes in Idiopathic Intracranial Hypertension with Venous Sinus Stenosis Stenting.","authors":"Jie He, Hongchao Yang, Raynald, Xu Tong, Yilong Wang, Zhongrong Miao, Dapeng Mo","doi":"10.1007/s00062-024-01477-1","DOIUrl":"10.1007/s00062-024-01477-1","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the factors influencing favourable clinical outcomes in idiopathic intracranial hypertension (IIH) patients with venous sinus stenosis (VSS) who received stenting treatment.</p><p><strong>Methods: </strong>In this prospective cohort study, we analyzed a total of 172 IIH patients with VSS treated with venous sinus stenting. Clinical outcomes were categorized as either \"complete resolved\" or \"improved\". We employed multivariable logistic regression modeling to identify independent factors associated with the clinical outcomes. The predictive accuracy of the model was assessed using receiver operating characteristic (ROC) analysis.</p><p><strong>Results: </strong>Out of the total cohort, 126 patients exhibited asymptomatic clinical outcomes, while 46 patients showed improved clinical outcomes. Patients with asymptomatic clinical outcomes demonstrated notably lower preoperative BMI (26.8 kg/m² versus 28.7 kg/m², P = 0.013). In multivariate analysis, preoperative BMI (odds ratio [OR] = 1.108, 95% confidence interval [CI] = 1.009-1.216) was an independent factor of complete resolution of the symptoms. In the receiver operating characteristic (ROC) analysis, the identified cut-off BMI for the highest sensitivity (0.5) and specificity (0.754) was determined to be 29.3 kg/m².</p><p><strong>Conclusion: </strong>Lower BMI may be associated with the complete resolution of symptoms in IIH patients with VSS who received venous sinus stenting treatment.</p>","PeriodicalId":49298,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"287-293"},"PeriodicalIF":2.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}